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Original Article

Animal Models of Liver Fibrosis

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Pages 1137-1143 | Published online: 08 Jul 2009

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Maryam Barghi, Mahboobeh Ashrafi, Mahmoud Aminlari, Fateme Namazi & Saeed Nazifi. (2021) The protective effect of Zataria multiflora Boiss essential oil on CCl4 induced liver fibrosis in rats. Drug and Chemical Toxicology 44:3, pages 229-237.
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Abdel Nasser B. Singab, Nahla A. Ayoub, Eman N. Ali & Nada M. Mostafa. (2010) Antioxidant and hepatoprotective activities of Egyptian moraceous plants against carbon tetrachloride-induced oxidative stress and liver damage in rats. Pharmaceutical Biology 48:11, pages 1255-1264.
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Jian Wu, Åke Danielsson & Mark A Zern. (1999) Toxicity of hepatotoxins: new insights into mechanisms and therapy. Expert Opinion on Investigational Drugs 8:5, pages 585-607.
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Articles from other publishers (40)

Jian Wu. (2016) Utilization of animal models to investigate nonalcoholic steatohepatitis-associated hepatocellular carcinoma. Oncotarget 7:27, pages 42762-42776.
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Mi-Gyeong Gwon, Jung-Yeon Kim, Hyun-Jin An, Woon-Hae Kim, Hyemin Gu, Min-Kyung Kim, Sok Pak & Kwan-Kyu Park. (2018) Antifibrotic Effect of Smad Decoy Oligodeoxynucleotide in a CCl4-Induced Hepatic Fibrosis Animal Model. Molecules 23:8, pages 1991.
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Ahmed Sekkien, Noha Swilam, Sherif Ebada, Ahmed Esmat, Ahmed El-Khatib, Michael Linscheid & Abdel Singab. (2018) Polyphenols from Tamarix nilotica: LC–ESI-MSn Profiling and In Vivo Antifibrotic Activity. Molecules 23:6, pages 1411.
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Yoshihisa Takahashi & Toshio Fukusato. 2017. Animal Models for the Study of Human Disease. Animal Models for the Study of Human Disease 313 339 .
Joyeeta Dutta-Moscato, Alexey Solovyev, Qi Mi, Taichiro Nishikawa, Alejandro Soto-Gutierrez, Ira J. Fox & Yoram Vodovotz. (2014) A Multiscale Agent-Based in silico Model of Liver Fibrosis Progression. Frontiers in Bioengineering and Biotechnology 2.
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Yan LiuChristoph MeyerChengfu Xu, Honglei WengClaus Hellerbrand, Peter ten DijkeSteven Dooley. (2013) Animal models of chronic liver diseases. American Journal of Physiology-Gastrointestinal and Liver Physiology 304:5, pages G449-G468.
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April M. Chow, Mingqian Tan, Darwin S. Gao, Shu Juan Fan, Jerry S. Cheung, Zhongwei Qiao, Kwan Man, Zheng-Rong Lu & Ed X. Wu. (2013) Molecular MRI of Liver Fibrosis by a Peptide-Targeted Contrast Agent in an Experimental Mouse Model. Investigative Radiology 48:1, pages 46-54.
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Yuki Ikebuchi, Hidetoshi Shimizu, Kousei Ito, Takashi Yoshikado, Yoshihide Yamanashi, Tappei Takada & Hiroshi Suzuki. (2012) Ursodeoxycholic acid stimulates the formation of the bile canalicular network. Biochemical Pharmacology 84:7, pages 925-935.
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April M. Chow, Darwin S. Gao, Shu Juan Fan, Zhongwei Qiao, Frank Y. Lee, Jian Yang, Kwan Man & Ed X. Wu. (2012) Liver fibrosis: An intravoxel incoherent motion (IVIM) study. Journal of Magnetic Resonance Imaging 36:1, pages 159-167.
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April M. Chow, Darwin S. Gao, Shu Juan Fan, Zhongwei Qiao, Frank Y. Lee, Jian Yang, Kwan Man & Ed X. Wu. (2012) Measurement of liver T 1 and T 2 relaxation times in an experimental mouse model of liver fibrosis . Journal of Magnetic Resonance Imaging 36:1, pages 152-158.
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Kei Moriya, Keiko Sakai, Michel H. Yan & Takao Sakai. (2012) Fibronectin is essential for survival but is dispensable for proliferation of hepatocytes in acute liver injury in mice. Hepatology 56:1, pages 311-321.
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Nadia M. Hamdy & Ebtehal El-Demerdash. (2012) New therapeutic aspect for carvedilol: Antifibrotic effects of carvedilol in chronic carbon tetrachloride-induced liver damage. Toxicology and Applied Pharmacology 261:3, pages 292-299.
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Ahmad R. Bassiouny, Amira Zaky, Faten Fawky & Kamal M. Kandeel. (2011) Alteration of AP-endonuclease1 expression in curcumin-treated fibrotic rats. Annals of Hepatology 10:4, pages 516-530.
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Ruchi Bansal, Eduard Post, Johannes H. Proost, Alie de Jager-Krikken, Klaas Poelstra & Jai Prakash. (2011) PEGylation improves pharmacokinetic profile, liver uptake and efficacy of Interferon gamma in liver fibrosis. Journal of Controlled Release 154:3, pages 233-240.
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Aly M. El-Sayed, Shahira M. Ezzat, Maha M. Salama & Amany A. Sleem. (2011) Hepatoprotective and cytotoxic activities of Delonix regia flower extracts. Pharmacognosy Journal 3:19, pages 49-56.
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Rebecca G. Wells. 2011. Molecular Pathology of Liver Diseases. Molecular Pathology of Liver Diseases 449 466 .
Jerry S. Cheung, Shu Juan Fan, Darwin S. Gao, April M. Chow, Kwan Man & Ed X. Wu. (2010) Diffusion tensor imaging of liver fibrosis in an experimental model. Journal of Magnetic Resonance Imaging 32:5, pages 1141-1148.
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Myung-Ae Bae, Sang Dal Rhee, Won Hoon Jung, Jin Hee Ahn, Byoung-Joon Song & Hyae Gyeong Cheon. (2010) Selective inhibition of activated stellate cells and protection from carbon tetrachloride-induced liver injury in rats by a new PPARγ agonist KR62776. Archives of Pharmacal Research 33:3, pages 433-442.
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Li-ping Yuan, Fei-hu Chen, Lu Ling, Hu Bo, Zhi-wu Chen, Fan Li, Ming-mei Zhong & Li-juan Xia. (2008) Protective effects of total flavonoids of Bidens bipinnata L. against carbon tetrachloride-induced liver fibrosis in rats . Journal of Pharmacy and Pharmacology 60:10, pages 1393-1402.
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. (2009) Inhibitory Effects of Chimeric Decoy Oligodeoxynucleotide in the Regulation of Transcription Factors NF-κB and Sp1 in an Animal Model of Liver Cirrhosis. Journal of Life Science 19:10, pages 1360-1367.
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Perumal Nagarajan, Ramasamy Venkatesan, Mahesh Kumar, Abul Usmani & Subeer S. Majumdar. (2008) Macaca radiata (bonnet monkey): a spontaneous model of nonalcoholic fatty liver disease. Liver International 28:6, pages 856-864.
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Kazuhiro Suzumura, Tadamichi Hirano, Gakuhei Son, Yuji Iimuro, Hiroaki Mizukami, Keiya Ozawa & Jiro Fujimoto. (2007) Adeno-associated virus vector-mediated production of hepatocyte growth factor attenuates liver fibrosis in mice. Hepatology International 2:1, pages 80-88.
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Gakuhei Son, Yuji Iimuro, Ekihiro Seki, Tadamichi Hirano, Yasufumi Kaneda & Jiro Fujimoto. (2007) Selective inactivation of NF-κB in the liver using NF-κB decoy suppresses CCl 4 -induced liver injury and fibrosis . American Journal of Physiology-Gastrointestinal and Liver Physiology 293:3, pages G631-G639.
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Young-Suk Lim, Han Chu Lee & Hyo-Suk Lee. (2006) Switch of cadherin expression from E- to N-type during the activation of rat hepatic stellate cells. Histochemistry and Cell Biology 127:2, pages 149-160.
Crossref
David Shaw. 2007. xPharm: The Comprehensive Pharmacology Reference. xPharm: The Comprehensive Pharmacology Reference 1 5 .
Atef M. Al-Attar. (2006) Chemopreventive Effect of Cinnamon Extract on Carbon Tetrachloride-Induced Physiological Changes in the Frog, Rana ridibunda. Journal of Applied Sciences 7:1, pages 79-90.
Crossref
Kan-Zhi Liu, Angela Man, R. Anthony Shaw, Binhua Liang, Zhaolin Xu & Yuwen Gong. (2006) Molecular determination of liver fibrosis by synchrotron infrared microspectroscopy. Biochimica et Biophysica Acta (BBA) - Biomembranes 1758:7, pages 960-967.
Crossref
Nicholas J. Laping & StÉphane Huet. 2006. Smad Signal Transduction. Smad Signal Transduction 443 459 .
Joan Clària & Wladimiro Jiménez. 2005. Ascites and Renal Dysfunction in Liver Disease. Ascites and Renal Dysfunction in Liver Disease 215 226 .
Abdel Nasser B. Singab, Diaa T. A. Youssef, Eman Noaman & Saeed Kotb. (2005) Hepatoprotective effect of flavonol glycosides rich fraction from egyptianVicia calcarata desf. Against CCI4-induced liver damage in rats. Archives of Pharmacal Research 28:7, pages 791-798.
Crossref
Anne-Charlotte de Gouville, Valerie Boullay, Gael Krysa, Julia Pilot, Jean-Marie Brusq, Florence Loriolle, Jean-Michel Gauthier, Stephen A Papworth, Alain Laroze, Françoise Gellibert & Stephane Huet. (2005) Inhibition of TGF- β signaling by an ALK5 inhibitor protects rats from dimethylnitrosamine-induced liver fibrosis . British Journal of Pharmacology 145:2, pages 166-177.
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Ming-Ling Chang. (2005) Comparison of murine cirrhosis models induced by hepatotoxin administration and common bile duct ligation. World Journal of Gastroenterology 11:27, pages 4167.
Crossref
JC Lambert & GE Arteel. 2005. Comprehensive Handbook of Alcohol Related Pathology. Comprehensive Handbook of Alcohol Related Pathology 1535 1549 .
Jian-Gao Fan. (2003) Effects of low-calorie diet on steatohepatitis in rats with obesity and hyperlipidemia. World Journal of Gastroenterology 9:9, pages 2045.
Crossref
Andreas Geier, Suk Kyum Kim, Thomas Gerloff, Christoph G Dietrich, Frank Lammert, Saul J Karpen, Bruno Stieger, Peter J Meier, Siegfried Matern & Carsten Gartung. (2002) Hepatobiliary organic anion transporters are differentially regulated in acute toxic liver injury induced by carbon tetrachloride. Journal of Hepatology 37:2, pages 198-205.
Crossref
S Dogru-Abbasoglu, J Balkan, Ö Kanbaglõ, U Cevikbas, G Aykac-Toker & M Uysal. (2016) Aminoguanidine, an inducible nitric oxide synthase inhibitor, plus N-acetylcysteine treatment reduce the lipopolysaccharideaugmented hepatotoxicity in rats with cirrhosis. Human & Experimental Toxicology 21:7, pages 359-364.
Crossref
J Balkan, S Dogğru-Abbasoğlul, ö Kanbaglil, U Çevikbas, G Aykaç-Toker & M Uysal. (2016) Taurine has a protective effect against thioacetamide-induced liver cirrhosis by decreasing oxidative stress. Human & Experimental Toxicology 20:5, pages 251-254.
Crossref
Kaori Kajihara Takai, Shunji Hattori & Shinkichi Irie. (2001) Type V Collagen Distribution in Liver Is Reconstructed in Coculture System of Hepatocytes and Stellate Cells; The Possible Functions of Type V Collagen in Liver under Normal and Pathological Conditions.. Cell Structure and Function 26:5, pages 289-302.
Crossref
M.V. Kudryavtseva, A.V. Emelyanov, G.A. Sakuta, N.N. Bezborodkina & B.N. Kudryavtsev. (1998) Glycogen-forming function of hepatocytes in the rat regenerating cirrhotic liver after a partial hepatectomy. Tissue and Cell 30:2, pages 261-267.
Crossref

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