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Xenobiotica
the fate of foreign compounds in biological systems
Volume 41, 2011 - Issue 3
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Animal Pharmacokinetics and Metabolism

Pharmacokinetics of the prodrug thiamphenicol glycinate and its active parent compound thiamphenicol in beagle dogs following intravenous administration

Bing Yang
,
Yang LuCenter of Drug Metabolism and Pharmacokinetics, China Pharmaceutical University, Nanjing 210009, P. R. China
,
Jianheng ZhengCenter of Drug Metabolism and Pharmacokinetics, China Pharmaceutical University, Nanjing 210009, P. R. China
,
Jing ZhuCenter of Drug Metabolism and Pharmacokinetics, China Pharmaceutical University, Nanjing 210009, P. R. China
,
Jiake HeCenter of Drug Metabolism and Pharmacokinetics, China Pharmaceutical University, Nanjing 210009, P. R. China
,
Di ZhaoCenter of Drug Metabolism and Pharmacokinetics, China Pharmaceutical University, Nanjing 210009, P. R. China
,
Pengfei SongDepartment of Preclinical Development and Clinical Pharmacology, ArQule Inc., Woburn, MA 01801, USA
&
Xijing ChenCenter of Drug Metabolism and Pharmacokinetics, China Pharmaceutical University, Nanjing 210009, P. R. ChinaCorrespondence[email protected]
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Pages 226-231 | Received 03 Aug 2010, Accepted 24 Oct 2010, Published online: 23 Nov 2010

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Bing Yang, Ning Li, Yang Lu, Zhixia Qiu, Di Zhao, Pengfei Song & Xijing Chen. (2014) Pharmacokinetics of thiamphenicol glycinate and its active metabolite by single and multiple intravenous infusions in healthy Chinese volunteers. Xenobiotica 44:9, pages 819-826.
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Ning Li, Zhixia Qiu, Xuliang Wang, Tingting Li, Hui Ji, Yihua Zhang, Yang Lu, Di Zhao & Xijing Chen. (2014) Pharmacokinetics in Sprague-Dawley rats and Beagle dogs and in vitro metabolism of ZJM-289, a novel nitric dioxide donor. Xenobiotica 44:1, pages 59-69.
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Articles from other publishers (2)

Zhe Wang, Hui Yang, Wei Sun, Cheng-ke Huang, Xiao Cui, Xiang-jun Qiu, Qing-quan Lian & Zeng-shou Wang. (2014) UPLC?MS/MS determination of thiamphenicol in human plasma and its application to a pharmacokinetic study. Journal of Chromatography B 967, pages 235-239.
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Zhixia Qiu, Ning Li, Xin Wang, Fengjie Tian, Qi Liu, Ling Song, Zhen Fan, Yang Lu & Xijing Chen. (2013) Pharmacokinetics of Vicagrel, a Promising Analog of Clopidogrel, in Rats and Beagle Dogs. Journal of Pharmaceutical Sciences 102:2, pages 741-749.
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