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Xenobiotica
the fate of foreign compounds in biological systems
Volume 41, 2011 - Issue 12
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Clinical Pharmacokinetics and Metabolism

Disposition, metabolism and mass balance of [14C]apremilast following oral administration

Matthew HoffmannDrug Metabolism and Pharmacokinetics Department, Celgene, Summit, NJ, USACorrespondence[email protected]
,
Gondi KumarDrug Metabolism and Pharmacokinetics Department, Celgene, Summit, NJ, USA
,
Peter SchaferTranslational Development Department, Celgene, Summit, NJ, USA
,
Dorota CedzikTranslational Development Department, Celgene, Summit, NJ, USA
,
Lori CaponeTranslational Development Department, Celgene, Summit, NJ, USA
,
Kei-Lai FongAccellient Partners LLC, Berkeley, CA, USA
,
Zheming GuXenoBiotic Laboratories, Plainsboro, NJ, USA
,
Dennis HellerXenoBiotic Laboratories, Plainsboro, NJ, USA
,
Hao FengXenoBiotic Laboratories, Plainsboro, NJ, USA
,
Sekhar SurapaneniDrug Metabolism and Pharmacokinetics Department, Celgene, Summit, NJ, USA
,
Oscar LaskinR2D Pharma Services LLC, Princeton, NJ, USA
&
Anfan WuExploratory Clinical Pharmacology Department, Celgene, Summit, NJ, USA
 show all
Pages 1063-1075 | Received 26 May 2011, Accepted 08 Jul 2011, Published online: 23 Aug 2011

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Pooja Kulkarni & Ashwini Deshpande. (2021) Analytical Methods for Determination of Apremilast from Bulk, Dosage Form and Biological Fluids: A Critical Review. Critical Reviews in Analytical Chemistry 51:3, pages 258-267.
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Leigh C Walker & Andrew J Lawrence. (2018) Investigational drug therapies in phase I and phase II clinical trials for alcohol use disorders. Expert Opinion on Investigational Drugs 27:8, pages 677-690.
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Luca Bianchi, Ester Del Duca, Marco Romanelli, Rosita Saraceno, Sergio Chimenti & Andrea Chiricozzi. (2016) Pharmacodynamic assessment of apremilast for the treatment of moderate-to-severe plaque psoriasis. Expert Opinion on Drug Metabolism & Toxicology 12:9, pages 1121-1128.
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Alejandro Souto & Juan J Gómez-Reino. (2015) Apremilast for the treatment of psoriatic arthritis. Expert Review of Clinical Immunology 11:12, pages 1281-1290.
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Swapna Busa & Arthur Kavanaugh. (2015) Drug safety evaluation of apremilast for treating psoriatic arthritis. Expert Opinion on Drug Safety 14:6, pages 979-985.
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Sowmya Varada, Suzanne J Tintle & Alice B Gottlieb. (2014) Apremilast for the treatment of psoriatic arthritis. Expert Review of Clinical Pharmacology 7:3, pages 239-250.
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Brandon Shutty, Cameron West, Megan Pellerin & Steven Feldman. (2012) Apremilast as a treatment for psoriasis. Expert Opinion on Pharmacotherapy 13:12, pages 1761-1770.
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Neal Kumar, Ari M Goldminz, Noori Kim & Alice B Gottlieb. (2013) Phosphodiesterase 4-targeted treatments for autoimmune diseases. BMC Medicine 11:1.
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