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Xenobiotica
the fate of foreign compounds in biological systems
Volume 45, 2015 - Issue 2
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Research Article

Immunochemical quantification of cynomolgus CYP2J2, CYP4A and CYP4F enzymes in liver and small intestine

Shotaro UeharaPharmacokinetics and Bioanalysis Center, Shin Nippon Biomedical Laboratories, Ltd., Kainan, Wakayama, Japan, ;Laboratory of Drug Metabolism and Pharmacokinetics, Showa Pharmaceutical University, Machida, Tokyo, Japan,
,
Norie MurayamaLaboratory of Drug Metabolism and Pharmacokinetics, Showa Pharmaceutical University, Machida, Tokyo, Japan,
,
Yasuharu NakanishiPharmacokinetics and Bioanalysis Center, Shin Nippon Biomedical Laboratories, Ltd., Kainan, Wakayama, Japan,
,
Chika NakamuraPharmacokinetics and Bioanalysis Center, Shin Nippon Biomedical Laboratories, Ltd., Kainan, Wakayama, Japan,
,
Takanori HashizumeFaculty of Pharmacy, Osaka Ohtani University, Tondabayashi, Osaka, Japan, and
,
Darryl C. ZeldinDivision of Intramural Research, National Institute of Environmental Health Sciences, Research Triangle Park, Durham, NC, USA
,
Hiroshi YamazakiLaboratory of Drug Metabolism and Pharmacokinetics, Showa Pharmaceutical University, Machida, Tokyo, Japan, Correspondence[email protected]
&
Yasuhiro UnoPharmacokinetics and Bioanalysis Center, Shin Nippon Biomedical Laboratories, Ltd., Kainan, Wakayama, Japan, Correspondence[email protected]
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Pages 124-130 | Received 17 Jul 2014, Accepted 05 Aug 2014, Published online: 20 Aug 2014

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Ayaka Kojima, Ayuka Sogabe, Masayuki Nadai & Miki Katoh. (2021) Species differences in oxidative metabolism of regorafenib. Xenobiotica 51:12, pages 1400-1407.
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Shotaro Uehara, Yasuhiro Uno, Takashi Inoue, Eriko Okamoto, Erika Sasaki & Hiroshi Yamazaki. (2016) Marmoset cytochrome P450 2J2 mainly expressed in small intestines and livers effectively metabolizes human P450 2J2 probe substrates, astemizole and terfenadine. Xenobiotica 46:11, pages 977-985.
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Maret G. Traber. 2023. Encyclopedia of Human Nutrition. Encyclopedia of Human Nutrition 545 555 .
Yasuhiro Uno, Norie Murayama, Moe Ijiri, Hiroaki Kawaguchi, Osamu Yamato, Mitsuya Shiraishi, Atsushi Asano, Hiroki Teraoka, Hazuki Mizukawa, Shouta M.M. Nakayama, Yoshinori Ikenaka, Mayumi Ishizuka & Hiroshi Yamazaki. (2022) Cytochrome P450 2J Genes Are Expressed in Dogs, Cats, and Pigs, and Encode Functional Drug-Metabolizing Enzymes . Drug Metabolism and Disposition 50:11, pages 1434-1441.
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Dmitri R. Davydov, Bikash Dangi, Guihua Yue, Deepak S. Ahire, Bhagwat Prasad & Victor G. Zgoda. (2022) Exploring the Interactome of Cytochrome P450 2E1 in Human Liver Microsomes with Chemical Crosslinking Mass Spectrometry. Biomolecules 12:2, pages 185.
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Cong Hu, Hong-Wei Li, Jia-Qun Ke, Xue-Chun Yu, Mei-Yu Zhao, Xin-Yue Shi, Lin-Jing Wu, Xi-Lan Tang & Yin-Hua Xiong. (2022) Metabolic profiling of lysophosphatidylcholines in chlorpromazine hydrochloride- and N -acetyl- p -amino-phenoltriptolide-induced liver injured rats based on ultra-performance liquid chromatography quadrupole time-of-flight mass spectrometry . Human & Experimental Toxicology 41, pages 096032712211083.
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Yasuhiro Uno, Shotaro Uehara & Hiroshi Yamazaki. 2022. Pharmacology and Toxicology of Cytochrome P450 – 60th Anniversary. Pharmacology and Toxicology of Cytochrome P450 – 60th Anniversary 329 364 .
Maret G. Traber & Brian Head. (2021) Vitamin E: How much is enough, too much and why!. Free Radical Biology and Medicine 177, pages 212-225.
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Maret G Traber, Scott W Leonard, Ifechukwude Ebenuwa, Pierre-Christian Violet, Mahtab Niyyati, Sebastian Padayatty, Sheila Smith, Gerd Bobe & Mark Levine. (2021) Vitamin E catabolism in women, as modulated by food and by fat, studied using 2 deuterium-labeled α-tocopherols in a 3-phase, nonrandomized crossover study. The American Journal of Clinical Nutrition 113:1, pages 92-103.
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Meetal Solanki, Amy Pointon, Barry Jones & Karl Herbert. (2018) Cytochrome P450 2J2: Potential Role in Drug Metabolism and Cardiotoxicity. Drug Metabolism and Disposition 46:8, pages 1053-1065.
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Shotaro Uehara, Yasuhiro Uno & Hiroshi Yamazaki. (2017) Hepatic expression of cytochrome P450 enzymes in non-human primate species. Journal of Medical Primatology 46:6, pages 347-351.
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Fang Xie, Xinxin Ding & Qing-Yu Zhang. (2016) An update on the role of intestinal cytochrome P450 enzymes in drug disposition. Acta Pharmaceutica Sinica B 6:5, pages 374-383.
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R. S. Foti & D. K. Dalvie. (2016) Cytochrome P450 and Non-Cytochrome P450 Oxidative Metabolism: Contributions to the Pharmacokinetics, Safety, and Efficacy of Xenobiotics. Drug Metabolism and Disposition 44:8, pages 1229-1245.
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