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Xenobiotica
the fate of foreign compounds in biological systems
Volume 45, 2015 - Issue 6
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Research Article

In vitro metabolism of a novel JNK inhibitor tanzisertib: interspecies differences in oxido-reduction and characterization of enzymes involved in metabolism

Christian AtsrikuDepartment of Drug Metabolism and Pharmacokinetics, Celgene Corporation, Summit, NJ, USA and Correspondence[email protected]
,
Matthew HoffmannDepartment of Drug Metabolism and Pharmacokinetics, Celgene Corporation, Summit, NJ, USA and
,
Mehran MoghaddamDepartment of Drug Metabolism and Pharmacokinetics, Celgene Corporation, San Diego, CA, USA
,
Gondi KumarDepartment of Drug Metabolism and Pharmacokinetics, Celgene Corporation, Summit, NJ, USA and
&
Sekhar SurapaneniDepartment of Drug Metabolism and Pharmacokinetics, Celgene Corporation, Summit, NJ, USA and
Pages 465-480 | Received 15 Oct 2014, Accepted 20 Nov 2014, Published online: 05 Dec 2014

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