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Xenobiotica
the fate of foreign compounds in biological systems
Volume 45, 2015 - Issue 6
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Research Article

The mechanism of rapamycin in the intervention of paraquat-induced acute lung injury in rats

Da ChenEmergency Department, the First Affiliated Hospital of China Medical University, Shenyang, China and
,
Guangyu JiaoRespiratory Department and Intensive Care Unit, Shengjing Hospital of China Medical University, Shenyang, China
,
Tao MaEmergency Department, the First Affiliated Hospital of China Medical University, Shenyang, China and
,
Xiaowei LiuEmergency Department, the First Affiliated Hospital of China Medical University, Shenyang, China and
,
Chen YangEmergency Department, the First Affiliated Hospital of China Medical University, Shenyang, China and
&
Zhi LiuEmergency Department, the First Affiliated Hospital of China Medical University, Shenyang, China and Correspondence[email protected]
Pages 538-546 | Received 28 Oct 2014, Accepted 02 Dec 2014, Published online: 19 Dec 2014

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Read on this site (2)

Rajasekaran Subbiah & Rajnarayan R. Tiwari. (2021) The herbicide paraquat-induced molecular mechanisms in the development of acute lung injury and lung fibrosis. Critical Reviews in Toxicology 51:1, pages 36-64.
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Yue Hu, Jian Lou, Yuan-Yuan Mao, Tian-Wen Lai, Li-Yao Liu, Chen Zhu, Chao Zhang, Juan Liu, Yu-Yan Li, Fan Zhang, Wen Li, Song-Min Ying, Zhi-Hua Chen & Hua-Hao Shen. (2016) Activation of MTOR in pulmonary epithelium promotes LPS-induced acute lung injury. Autophagy 12:12, pages 2286-2299.
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Articles from other publishers (8)

Xuxia Wei, Xiaomeng Yi, Haijin Lv, Xin Sui, Pinglan Lu, Lijuan Li, Yuling An, Yang Yang, Huimin Yi & Guihua Chen. (2020) MicroRNA-377-3p released by mesenchymal stem cell exosomes ameliorates lipopolysaccharide-induced acute lung injury by targeting RPTOR to induce autophagy. Cell Death & Disease 11:8.
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Justine R. Horne & Marie-Claude Vohl. (2020) Biological plausibility for interactions between dietary fat, resveratrol, ACE2 , and SARS-CoV illness severity . American Journal of Physiology-Endocrinology and Metabolism 318:5, pages E830-E833.
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Nagaraja SreeHarsha. (2020) Embelin impact on paraquat‐induced lung injury through suppressing oxidative stress, inflammatory cascade, and MAPK/NF‐κB signaling pathway. Journal of Biochemical and Molecular Toxicology 34:4.
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Wenlin Tai, Shuhao Deng, Wenjuan Wu, ZhenKun Li, Wen Lei, Yin Wang, Chanthasone Vongphouttha, Tao Zhang & Zhaoxing Dong. (2019) Rapamycin attenuates the paraquat‐induced pulmonary fibrosis through activating Nrf2 pathway. Journal of Cellular Physiology 235:2, pages 1759-1768.
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Jennifer Carlson, Lindsey Price & Huai Deng. 2020. Nrf2 and its Modulation in Inflammation. Nrf2 and its Modulation in Inflammation 51 76 .
N Feng, Z Bian, X Zhang, C Wang & J Chen. (2019) Rapamycin reduces mortality in acute-stage paraquat-induced toxicity in zebrafish. Singapore Medical Journal 60:5, pages 241-246.
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Qiong-Feng Chen, Xiao-Dong Kuang, Qi-Feng Yuan, Hua Hao, Ting Zhang, Yong-Hong Huang & Xiao-Yan Zhou. (2018) Lipoxin A 4 attenuates LPS-induced acute lung injury via activation of the ACE2-Ang-(1-7)-Mas axis . Innate Immunity 24:5, pages 285-296.
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Kerui Fan, Ling Lin, Qing Ai, Jingyuan Wan, Jie Dai, Gang Liu, Li Tang, Yongqiang Yang, Pu Ge, Rong Jiang & Li Zhang. (2018) Lipopolysaccharide-Induced Dephosphorylation of AMPK-Activated Protein Kinase Potentiates Inflammatory Injury via Repression of ULK1-Dependent Autophagy. Frontiers in Immunology 9.
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