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Xenobiotica
the fate of foreign compounds in biological systems
Volume 45, 2015 - Issue 6
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Research Article

Key determinants of the circulatory exposure of organic anions: differences in hepatic uptake between multidrug resistance-associated protein 2 (Mrp2)-deficient rats and wild-type rats

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Pages 556-562 | Received 22 Oct 2014, Accepted 09 Dec 2014, Published online: 24 Dec 2014

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A. L. Dzierlenga, J. D. Clarke, D. M. Klein, T. Anumol, S. A. Snyder, H. Li & N. J. Cherrington. (2016) Biliary Elimination of Pemetrexed Is Dependent on Mrp2 in Rats: Potential Mechanism of Variable Response in Nonalcoholic Steatohepatitis. Journal of Pharmacology and Experimental Therapeutics 358:2, pages 246-253.
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