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Research Article

Preparation of biodegradable microcapsules containing zidovudine (AZT) using solvent evaporation technique

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Pages 257-267 | Received 22 Nov 1994, Accepted 27 Jul 1995, Published online: 27 Sep 2008

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Jucimary V. Santos, Maria Eugénia T. Pina, M. Paula M. Marques & Luís A. E. Batista de Carvalho. (2013) New sustained release of Zidovudine Matrix tablets − cytotoxicity toward Caco-2 cells. Drug Development and Industrial Pharmacy 39:8, pages 1154-1166.
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Boris Polyak & Gary Friedman. (2009) Magnetic targeting for site-specific drug delivery: applications and clinical potential. Expert Opinion on Drug Delivery 6:1, pages 53-70.
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T.K. Mandal. (1999) Effect of solvent on the characteristics of pentamidine loaded microcapsule. Journal of Biomaterials Science, Polymer Edition 10:1, pages 1-17.
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Tarun K. Mandal. (1998) Evaluation of a Novel Phase Separation Technique for the Encapsulation of Water-Soluble Drugs in Biodegradable Polymer. Drug Development and Industrial Pharmacy 24:7, pages 623-629.
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D. J. Burgess & S. Ponsart. (1998) β-Glucuronidase activity following complex coacervation and spray drying microencapsulation. Journal of Microencapsulation 15:5, pages 569-579.
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T. K. Mandal, M. Shekleton, E. Onyebueke, L. Washington & T. Penson. (1996) Effect of formulation and processing factors on the characteristics of biodegradable microcapsules of zidovudine. Journal of Microencapsulation 13:5, pages 545-557.
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Articles from other publishers (9)

R. Ramanathan, Y. Jiang, B. Read, S. Golan-Paz & K.A. Woodrow. (2016) Biophysical characterization of small molecule antiviral-loaded nanolipogels for HIV-1 chemoprophylaxis and topical mucosal application. Acta Biomaterialia 36, pages 122-131.
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Giovanna Giacalone, Hervé Hillaireau & Elias Fattal. (2015) Improving bioavailability and biodistribution of anti-HIV chemotherapy. European Journal of Pharmaceutical Sciences 75, pages 40-53.
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Raghavendra C. Mundargi, Vidhya Rangaswamy & Tejraj M. Aminabhavi. (2011) Spray drying technique to produce controlled release formulations of zidovudine—an anti‐HIV drug. Journal of Applied Polymer Science 122:4, pages 2244-2251.
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Valquíria Miwa Hanai Yoshida, José Martins de Oliveira Junior, Marcos Moisés Gonçalves, Marta Maria Duarte Carvalho Vila & Marco Vinícius Chaud. (2011) Development and Evaluation of a Floating Multiparticulate Gastroretentive System for Modified Release of AZT. AAPS PharmSciTech 12:2, pages 658-664.
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Christoph Brochhausen, Rolf Zehbe, Bernhard Watzer, Sven Halstenberg, Franziska Gabler, Helmut Schubert & Charles James Kirkpatrick. (2009) Immobilization and controlled release of prostaglandin E 2 from poly-L-lactide- co -glycolide microspheres . Journal of Biomedical Materials Research Part A 91A:2, pages 454-462.
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Hong Zhao, Jeffrey Gagnon & Urs O Häfeli. (2007) Process and formulation variables in the preparation of injectable and biodegradable magnetic microspheres. BioMagnetic Research and Technology 5:1.
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T.K. Mandal, L.A. Bostanian, R.A. Graves, S.R. Chapman & T.U. Idodo. (2001) Porous biodegradable microparticles for delivery of pentamidine. European Journal of Pharmaceutics and Biopharmaceutics 52:1, pages 91-96.
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Diana P. Callender, Nalini Jayaprakash, Aaron Bell, Vidmantas Petraitis, Ruta Petratienes, Myrna Candelario, Robert Schaufele, James M. Dunn, Shizuko Sei, Thomas J. Walsh & Frank M. Balis. (1999) Pharmacokinetics of Oral Zidovudine Entrapped in Biodegradable Nanospheres in Rabbits. Antimicrobial Agents and Chemotherapy 43:4, pages 972-974.
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Tarun K. Mandal & Srini Tenjarla. (1996) Preparation of biodegradable microcapsules of zidovudine using solvent evaporation: Effect of the modification of aqueous phase. International Journal of Pharmaceutics 137:2, pages 187-197.
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