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Original Article

Vitamin A is present as retinol in the tears of humans and rabbits

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Pages 815-822 | Received 15 Sep 1983, Accepted 27 Mar 1984, Published online: 02 Jul 2009

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (12)

Elias Chelala, Ali Dirani, Ali Fadlallah & Sharbel Fahd. (2013) The role of topical vitamin A in promoting healing in surface refractive procedures: a prospective randomized controlled study. Clinical Ophthalmology 7, pages 1913-1918.
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Akito Odaka, Hiroshi Toshida, Toshihiko Ohta, Nobuhito Tabuchi, Daisuke Koike, Chikako Suto & Akira Murakami. (2012) Efficacy of retinol palmitate eye drops for dry eye in rabbits with lacrimal gland resection. Clinical Ophthalmology 6, pages 1585-1593.
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Hiroshi Toshida, Akito Odaka, Daisuke Koike & Akira Murakami. (2008) Effect of Retinol Palmitate Eye Drops on Experimental Keratoconjunctival Epithelial Damage Induced byn-Heptanol in Rabbit. Current Eye Research 33:1, pages 13-18.
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Ben J. Glasgow, Adil R. Abduragimov, Zohreh Toossi Farahbakhsh, Kym F. Faull & Wayne L. Hubbell. (1995) Tear lipocalins bind a broad array of lipid ligands. Current Eye Research 14:5, pages 363-372.
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John L. Ubels, Megan H. Dennis, Brian W. Rigatti, Jean-Paul Vergnes, Randall Beatty & Paul R. Kinchington. (1995) Nuclear retinoic acid receptors in the lacrimal gland. Current Eye Research 14:11, pages 1055-1062.
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Ben J. Glasgow, Camilla Heinzmann, Tracy Kojis, Robert S. Sparkes, Thuluvancheri Mohandas & J. Bronwyn Bateman. (1993) Assignment of tear lipocalin gene to human chromosome 9q34–9qter. Current Eye Research 12:11, pages 1019-1023.
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A.K. Dobie, K.Y. Yang & N.C. De. (1991) High Performance Liquid Chromatographic Procedure for Retinoic Acid in Ophthalmic Solution. Journal of Liquid Chromatography 14:6, pages 1219-1226.
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Eric J. van Agtmaal, Martin W. Bloem, Andries J. Speek, Sastri Saowakontha, Wil H.P. Schreurs & Nicolaas J. van Haeringen. (1988) The effect of vitamin a supplementation on tear fluid retinol levels of marginally nourished preschool children. Current Eye Research 7:1, pages 43-48.
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A. Boonstra, A. C. Breebaart, C. J. J. Brinkman, L. Luyendijk, A. Kuizenga & A. Kijlstra. (1988) Factors influencing the quantitative determination of tear proteins by high performance liquid chromatography. Current Eye Research 7:9, pages 893-901.
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Andries J. Speek, Eric J. van Agtmaal, Sastri Saowakontha, Wil H.P. Schreurs & Nicolaas J. van Haeringen. (1986) Fluorometric determination of retinol in human tear fluid using high-performance liquid chromatography. Current Eye Research 5:11, pages 841-845.
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Chien-Chyou W. Chao & Susan M. Butala. (1986) Isolation and preliminary characterization of tear prealbumin from human ocular mucus. Current Eye Research 5:12, pages 895-901.
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John L. Ubels, Henry F. Edelhauser, Kevin M. Foley, John C. Liao & Philip Gressel. (1985) The efficacy of retinoic acid ointment for treatment of xerophthalmia and corneal epithelial wounds. Current Eye Research 4:10, pages 1049-1057.
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F W Fraunfelder, F T Fraunfelder & D R Illingworth. (1995) Adverse ocular effects associated with niacin therapy.. British Journal of Ophthalmology 79:1, pages 54-56.
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N. J. van Haeringen, V. M. W. Bodelier & P. S. J. Klaver. 1994. Lacrimal Gland, Tear Film, and Dry Eye Syndromes. Lacrimal Gland, Tear Film, and Dry Eye Syndromes 327 330 .
Sudi Patel, Colin Ferrier & Jeff Plaskow. 1994. Lacrimal Gland, Tear Film, and Dry Eye Syndromes. Lacrimal Gland, Tear Film, and Dry Eye Syndromes 285 287 .
S. Patel, J. Plaskow & C. Ferrier. (2009) The influence of vitamins and trace element supplements on the stability of the pre‐corneal tear film. Acta Ophthalmologica 71:6, pages 825-829.
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V. M. W. Bodelier, N. J. van Haeringen & P. S. Y. Klaver. (1993) Species differences in tears; Comparative investigation in the chimpanzee (Pan troglodytes). Primates 34:1, pages 77-84.
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A. Delaire, H. Lassagne & A.M.F. Gachon. (1992) New members of the lipocalin family in human tear fluid. Experimental Eye Research 55:4, pages 645-647.
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Elaine R. BermanElaine R. Berman. 1991. Biochemistry of the Eye. Biochemistry of the Eye 63 88 .
F.T. Fraunfelder & S. Martha Meyer. (1990) Amantadine and Corneal Deposits. American Journal of Ophthalmology 110:1, pages 96-97.
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A. Robinson, M. Prialnic, D. Deutsch & H. Savir. (1990) The Onset of Malignant Glaucoma After Prophylactic Laser Iridotomy. American Journal of Ophthalmology 110:1, pages 95-96.
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Hugh DavsonHugh Davson. 1990. Physiology of the Eye. Physiology of the Eye 786 807 .
Jimmy D. Bartlett & Siret D. Jaanus. 1989. Clinical Ocular Pharmacology. Clinical Ocular Pharmacology 801 842 .
Vivian Rismondo, John L. Ubels & Thomas B. Osgood. (1988) Tear secretion and lacrimal gland function of rabbits treated with isotretinoin. Journal of the American Academy of Dermatology 19:2, pages 280-285.
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Mark A. Lebowitz & Diane S. Berson. (1988) Ocular effects of oral retinoids. Journal of the American Academy of Dermatology 19:1, pages 209-211.
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A J Bron. (1988) Eyelid secretions and the prevention and production of disease. Eye 2:2, pages 164-171.
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F.T. Fraunfelder, James M. LaBraico & S. Martha Meyer. (1985) Adverse Ocular Reactions Possibly Associated With Isotretinoin. American Journal of Ophthalmology 100:4, pages 534-537.
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Sophie Catanese, Raoul Kanav Khanna, Antoine Lefevre, Hugo Alarcan, Pierre-Jean Pisella, Patrick Emond & Hélène Blasco. (2022) Validation of Metabolomic and Lipidomic Analyses of Human Tears Using Ultra-High-Performance Liquid Chromatography Tandem Mass Spectrometry. SSRN Electronic Journal.
Crossref

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