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Research Article

Hypofractionation does not increase radiation pneumonitis risk with modern conformal radiation delivery techniques

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Pages 1052-1057 | Received 20 May 2010, Accepted 02 Jun 2010, Published online: 13 Sep 2010

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Sana D Karam, Zachary D Horne, Robert L Hong, Don McRae, David Duhamel & Nadim M Nasr. (2014) Hypofractionated stereotactic body radiation therapy for elderly patients with stage IIB–IV nonsmall cell lung cancer who are ineligible for or refuse other treatment modalities. Lung Cancer: Targets and Therapy 5, pages 59-66.
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Ivan R. Vogelius, David C. Westerly, Marianne C. Aznar, George M. Cannon, Stine S. Korreman, Thomas R. Mackie, Minesh P. Mehta & Søren M. Bentzen. (2011) Estimated radiation pneumonitis risk after photon versus proton therapy alone or combined with chemotherapy for lung cancer. Acta Oncologica 50:6, pages 772-776.
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Articles from other publishers (21)

Albrecht Weiß, Steffen Löck, Ting Xu, Zhongxing Liao, Aswin L. Hoffmann & Esther G.C. Troost. (2024) Prediction of radiation pneumonitis using the effective α/β of lungs and heart in NSCLC patients treated with proton beam therapy. Radiotherapy and Oncology 190, pages 110013.
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Till Tobias Böhlen, Jean‐François Germond, Jean Bourhis, Marie‐Catherine Vozenin, Claude Bailat, François Bochud & Raphaël Moeckli. (2021) Technical Note: Break‐even dose level for hypofractionated treatment schedules. Medical Physics 48:11, pages 7534-7540.
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Alan E. Nahum & Richard P. Hill. 2018. Alternate Fractionation in Radiotherapy. Alternate Fractionation in Radiotherapy 5 19 .
Jing Zhao, Ellen D. Yorke, Ling Li, Brian D. Kavanagh, X. Allen Li, Shiva Das, Moyed Miften, Andreas Rimner, Jeffrey Campbell, Jinyu Xue, Andrew Jackson, Jimm Grimm, Michael T. Milano & Feng-Ming (Spring) Kong. (2016) Simple Factors Associated With Radiation-Induced Lung Toxicity After Stereotactic Body Radiation Therapy of the Thorax: A Pooled Analysis of 88 Studies. International Journal of Radiation Oncology*Biology*Physics 95:5, pages 1357-1366.
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Cathy Fleming, Daniel N. Cagney, Serena O’Keeffe, Sinead M. Brennan, John G. Armstrong & Brendan McClean. (2016) Normal tissue considerations and dose–volume constraints in the moderately hypofractionated treatment of non-small cell lung cancer. Radiotherapy and Oncology 119:3, pages 423-431.
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Michele Avanzo, Marco Trovo, Joseph Stancanello, Rajesh Jena, Mario Roncadin, Giulia Toffoli, Chiara Zuiani & Elvira Capra. (2015) Hypofractionation of partial breast irradiation using radiobiological models. Physica Medica 31:8, pages 1022-1028.
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Yasutaka Sugano, Masahiro Mizuta, Seishin Takao, Hiroki Shirato, Kenneth L. Sutherland & Hiroyuki Date. (2015) Optimization of the fractionated irradiation scheme considering physical doses to tumor and organ at risk based on dose–volume histograms. Medical Physics 42:11, pages 6203-6210.
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Alan E. Nahum. (2015) The Radiobiology of Hypofractionation. Clinical Oncology 27:5, pages 260-269.
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M. Avanzo, M. Trovo, C. Furlan, L. Barresi, A. Linda, J. Stancanello, L. Andreon, E. Minatel, M. Bazzocchi, M.G. Trovo & E. Capra. (2015) Normal tissue complication probability models for severe acute radiological lung injury after radiotherapy for lung cancer. Physica Medica 31:1, pages 1-8.
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Zong Xia Yang, Jian Tong Shen, You Ping Li, Kun Zhao, Cheng Hu Shi, Yue Xiao, Jia Jie Yu, Wu Dong Guo, Cui Cui Li, Ying Qiang Wang & Xiang Lian Li. (2014) Helical tomotherapy for cancer treatment: a rapid health technology assessment. Journal of Evidence-Based Medicine 7:3, pages 192-218.
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Vieri Scotti, Livia Marrazzo, Calogero Saieva, Benedetta Agresti, Icro Meattini, Isacco Desideri, Sara Cecchini, Silvia Bertocci, Ciro Franzese, Carla De Luca Cardillo, Giacomo Zei, Mauro Loi, Daniela Greto, Monica Mangoni, Pieroluigi Bonomo, Lorenzo Livi & Gian Paolo Biti. (2013) Impact of a breathing-control system on target margins and normal-tissue sparing in the treatment of lung cancer: experience at the radiotherapy unit of Florence University. La radiologia medica 119:1, pages 13-19.
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Guanzhong Gong, Ruozheng Wang, Yujie Guo, Deyin Zhai, Tonghai Liu, Jie Lu, Jinhu Chen, Chengxin Liu & Yong Yin. (2013) Reduced lung dose during radiotherapy for thoracic esophageal carcinoma: VMAT combined with active breathing control for moderate DIBH. Radiation Oncology 8:1.
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Aswin L Hoffmann & Alan E Nahum. (2013) Fractionation in normal tissues: the (α/β) eff concept can account for dose heterogeneity and volume effects . Physics in Medicine and Biology 58:19, pages 6897-6914.
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A.L. Appelt, I.R. Vogelius & S.M. Bentzen. (2013) Modern Hypofractionation Schedules for Tangential Whole Breast Irradiation Decrease the Fraction Size-corrected Dose to the Heart. Clinical Oncology 25:3, pages 147-152.
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Jan Unkelbach, David Craft, Ehsan Salari, Jagdish Ramakrishnan & Thomas Bortfeld. (2013) The dependence of optimal fractionation schemes on the spatial dose distribution. Physics in Medicine and Biology 58:1, pages 159-167.
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Heng-Jui Chang, Hui-Ling Ko, Cheng-Yen Lee, Ren-Hong Wu, Yu-Wung Yeh, Jiunn-Song Jiang, Shang-Jyh Kao & Kwan-Hwa Chi. (2012) Hypofractionated radiotherapy for primary or secondary oligometastatic lung cancer using Tomotherapy. Radiation Oncology 7:1.
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Masahiro Mizuta, Seishin Takao, Hiroyuki Date, Naoki Kishimoto, Kenneth L. Sutherland, Rikiya Onimaru & Hiroki Shirato. (2012) A Mathematical Study to Select Fractionation Regimen Based on Physical Dose Distribution and the Linear–Quadratic Model. International Journal of Radiation Oncology*Biology*Physics 84:3, pages 829-833.
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Jin-Bo Ma, Lin Wei, Er-Cheng Chen, Guang Qin, Yi-Peng Song, Xiang-Ming Chen & Chuan-Guo Hao. (2012) Moderately Hypofractionated Conformal Radiation Treatment of Thoracic Esophageal Carcinoma. Asian Pacific Journal of Cancer Prevention 13:8, pages 4163-4167.
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Aswin L. Hoffmann, Esther G.C. Troost, Henk Huizenga, Johannes H.A.M. Kaanders & Johan Bussink. (2012) Individualized Dose Prescription for Hypofractionation in Advanced Non-Small-Cell Lung Cancer Radiotherapy: An in silico Trial. International Journal of Radiation Oncology*Biology*Physics 83:5, pages 1596-1602.
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Alan E. Nahum & Julien Uzan. (2012) (Radio)Biological Optimization of External-Beam Radiotherapy. Computational and Mathematical Methods in Medicine 2012, pages 1-13.
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Nam P. Nguyen, Shane P. Krafft, Vincent Vinh-Hung, Paul Vos, Fabio Almeida, Siyoung Jang, Misty Ceizyk, Anand Desai, Rick Davis, Russ Hamilton, Homayoun Modarresifar, Dave Abraham & Lexie Smith-Raymond. (2011) Feasibility of tomotherapy to reduce normal lung and cardiac toxicity for distal esophageal cancer compared to three-dimensional radiotherapy. Radiotherapy and Oncology 101:3, pages 438-442.
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