Acta Oncologica, Volume 49, Issue 7 (2010)

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Acta Oncologica, Volume 49, Issue 7 (2010)

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Editorial

Editorial
Biology-guided adaptive radiation therapy – presence or future?
Cai Grau, Dag Rune Olsen, Jens Overgaard, Morten Høyer, Jacob Christian Lindegaard & Ludvig Paul Muren
Pages: 884-887
Published online: 13 Sep 2010
First Page PreviewforBiology-guided adaptive radiation therapy – presence or future? | Full Text | References | PDF (56.4 KB)
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Original Article

Article
Array CGH as a potential predictor of radiocurability in intermediate risk prostate cancer
Adrian S. Ishkanian, Gaetano Zafarana, John Thoms & Robert G. Bristow
Pages: 888-894
Published online: 30 Jun 2010
AbstractforArray CGH as a potential predictor of radiocurability in intermediate risk prostate cancer | Full Text | References | PDF (209.5 KB)
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Research Article

Article
Identifying pH independent hypoxia induced genes in human squamous cell carcinomas in vitro
Brita Singers Sørensen, Kasper Toustrup, Michael R. Horsman, Jens Overgaard & Jan Alsner
Pages: 895-905
Published online: 13 Sep 2010
AbstractforIdentifying pH independent hypoxia induced genes in human squamous cell carcinomas in vitro | Full Text | References | PDF (250.6 KB) | Supplemental
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Article
Non-invasive imaging of combretastatin activity in two tumor models: Association with invasive estimates
Thomas Nielsen, Rumi Murata, Ross J. Maxwell, Hans Stødkilde-Jørgensen, Leif Østergaard, Carsten D. Ley, Paul E. G. Kristjansen & Michael R. Horsman
Pages: 906-913
Published online: 13 Sep 2010
AbstractforNon-invasive imaging of combretastatin activity in two tumor models: Association with invasive estimates | Full Text | References | PDF (169.5 KB)
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Article
Preclinical dynamic 18F-FDG PET – tumor characterization and radiotherapy response assessment by kinetic compartment analysis
Kathrine Røe, Thomas B. Aleksandersen, Alexandr Kristian, Line B. Nilsen, Therese Seierstad, Hong Qu, Anne H. Ree, Dag R. Olsen & Eirik Malinen
Pages: 914-921
Published online: 13 Sep 2010
AbstractforPreclinical dynamic 18F-FDG PET – tumor characterization and radiotherapy response assessment by kinetic compartment analysis | Full Text | References | PDF (289 KB)
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Article
Assessing hypoxia in animal tumor models based on pharmocokinetic analysis of dynamic FAZA PET
Morten Busk, Ole Lajord Munk, Steen Jakobsen, Tobias Wang, Marianne Skals, Torben Steiniche, Michael Robert Horsman & Jens Overgaard
Pages: 922-933
Published online: 13 Sep 2010
AbstractforAssessing hypoxia in animal tumor models based on pharmocokinetic analysis of dynamic FAZA PET | Full Text | References | PDF (531.9 KB)
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Article
Identifying hypoxia in human tumors: A correlation study between 18F-FMISO PET and the Eppendorf oxygen-sensitive electrode
Lise Saksø Mortensen, Simon Buus, Marianne Nordsmark, Lise Bentzen, Ole Lajord Munk, Susanne Keiding & Jens Overgaard
Pages: 934-940
Published online: 13 Sep 2010
AbstractforIdentifying hypoxia in human tumors: A correlation study between 18F-FMISO PET and the Eppendorf oxygen-sensitive electrode | Full Text | References | PDF (262.5 KB)
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Article
Evaluating repetitive 18F-fluoroazomycin-arabinoside (18FAZA) PET in the setting of MRI guided adaptive radiotherapy in cervical cancer
Matthias Schuetz, Maximilian P. Schmid, Richard Pötter, Spyridoula Kommata, Dietmar Georg, Dobrica Lukic, Robert Dudczak, Kurt Kletter, Johannes Dimopoulos, Georgios Karanikas & Barbara Bachtiary
Pages: 941-947
Published online: 13 Sep 2010
AbstractforEvaluating repetitive 18F-fluoroazomycin-arabinoside (18FAZA) PET in the setting of MRI guided adaptive radiotherapy in cervical cancer | Full Text | References | PDF (204.3 KB)
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Article
Strategies of assessing and quantifying radiation treatment metabolic tumor response using F18 FDG Positron Emission Tomography (PET)
Martin Fuss
Pages: 948-955
Published online: 13 Sep 2010
AbstractforStrategies of assessing and quantifying radiation treatment metabolic tumor response using F18 FDG Positron Emission Tomography (PET) | Full Text | References | PDF (283 KB)
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Article
The use of FDG-PET/CT and diffusion-weighted magnetic resonance imaging for response prediction before, during and after preoperative chemoradiotherapy for rectal cancer
Maarten Lambrecht, Christophe Deroose, Sarah Roels, Vincent Vandecaveye, Freddy Penninckx, Xavier Sagaert, Eric van Cutsem, Frederik de Keyzer & Karin Haustermans
Pages: 956-963
Published online: 30 Jun 2010
AbstractforThe use of FDG-PET/CT and diffusion-weighted magnetic resonance imaging for response prediction before, during and after preoperative chemoradiotherapy for rectal cancer | Full Text | References | PDF (225.9 KB)
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Article
Feasibility of dose painting using volumetric modulated arc optimization and delivery
Stine S. Korreman, Silke Ulrich, Steve Bowen, Michael Deveau, Søren M. Bentzen & Robert Jeraj
Pages: 964-971
Published online: 13 Sep 2010
AbstractforFeasibility of dose painting using volumetric modulated arc optimization and delivery | Full Text | References | PDF (207.6 KB)
  • 1031 Views
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Article
Adaptive radiotherapy based on contrast enhanced cone beam CT imaging
Åste Søvik, Jan Rødal, Hege K. Skogmo, Christoffer Lervåg, Karsten Eilertsen & Eirik Malinen
Pages: 972-977
Published online: 13 Sep 2010
AbstractforAdaptive radiotherapy based on contrast enhanced cone beam CT imaging | Full Text | References | PDF (214.2 KB)
  • 1325 Views
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Article
Apparent diffusion coefficients in GEC ESTRO target volumes for image guided adaptive brachytherapy of locally advanced cervical cancer
Søren Haack, Erik Morre Pedersen, Sune N. Jespersen, Jesper F. Kallehauge, Jacob Christian Lindegaard & Kari Tanderup
Pages: 978-983
Published online: 13 Sep 2010
AbstractforApparent diffusion coefficients in GEC ESTRO target volumes for image guided adaptive brachytherapy of locally advanced cervical cancer | Full Text | References | PDF (154 KB)
  • 1356 Views
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Article
Methodologies for localizing loco-regional hypopharyngeal carcinoma recurrences in relation to FDG-PET positive and clinical radiation therapy target volumes
Anne K. Due, Stine Korreman, Søren M. Bentzen, Wolfgang Tomé, Edward Bender, Marianne Aznar, Ivan Vogelius, Anne K. Berthelsen, Claus A. Kristensen & Lena Specht
Pages: 984-990
Published online: 13 Sep 2010
AbstractforMethodologies for localizing loco-regional hypopharyngeal carcinoma recurrences in relation to FDG-PET positive and clinical radiation therapy target volumes | Full Text | References | PDF (123 KB)
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Article
Feasibility and sensitivity study of helical tomotherapy for dose painting plans
Michael A. Deveau, Stephen R. Bowen, David C. Westerly & Robert Jeraj
Pages: 991-996
Published online: 13 Sep 2010
AbstractforFeasibility and sensitivity study of helical tomotherapy for dose painting plans | Full Text | References | PDF (215.9 KB)
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Review Article

Review Article
Imaging of normal lung, liver and parotid gland function for radiotherapy
Mike Partridge, Tokihiro Yamamoto, Cai Grau, Morten Høyer & Ludvig Paul Muren
Pages: 997-1011
Published online: 13 Sep 2010
AbstractforImaging of normal lung, liver and parotid gland function for radiotherapy | Full Text | References | PDF (341.5 KB)
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Original Article

Article
Variability of textural features in FDG PET images due to different acquisition modes and reconstruction parameters
Paulina E. Galavis, Christian Hollensen, Ngoneh Jallow, Bhudatt Paliwal & Robert Jeraj
Pages: 1012-1016
Published online: 13 Sep 2010
AbstractforVariability of textural features in FDG PET images due to different acquisition modes and reconstruction parameters | Full Text | References | PDF (133.9 KB)
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Research Article

Article
Apparent Diffusion Coefficient (ADC) as a quantitative parameter in diffusion weighted MR imaging in gynecologic cancer: Dependence on b-values used
Jesper Folsted Kallehauge, Kari Tanderup, Søren Haack, Thomas Nielsen, Ludvig Paul Muren, Lars Fokdal, Jacob Christian Lindegaard & Erik Morre Pedersen
Pages: 1017-1022
Published online: 13 Sep 2010
AbstractforApparent Diffusion Coefficient (ADC) as a quantitative parameter in diffusion weighted MR imaging in gynecologic cancer: Dependence on b-values used | Full Text | References | PDF (198.9 KB)
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Article
Propagation of target and organ at risk contours in radiotherapy of prostate cancer using deformable image registration
Sara Thörnqvist, Jørgen B. B. Petersen, Morten Høyer, Lise N. Bentzen & Ludvig Paul Muren
Pages: 1023-1032
Published online: 13 Sep 2010
AbstractforPropagation of target and organ at risk contours in radiotherapy of prostate cancer using deformable image registration | Full Text | References | PDF (417.8 KB)
  • 1840 Views
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Article
Prediction of residual metabolic activity after treatment in NSCLC patients
Emmanuel Rios Velazquez, Hugo J. W. L. Aerts, Cary Oberije, Dirk De Ruysscher & Philippe Lambin
Pages: 1033-1039
Published online: 13 Sep 2010
AbstractforPrediction of residual metabolic activity after treatment in NSCLC patients | Full Text | References | PDF (173.2 KB)
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Article
Normal Tissue Complication Probability (NTCP) modeling of late rectal bleeding following external beam radiotherapy for prostate cancer: A Test of the QUANTEC-recommended NTCP model
Mitchell Liu, Vitali Moiseenko, Alexander Agranovich, Anand Karvat, Winkle Kwan, Ziad H. Saleh, Aditya A. Apte & Joseph O. Deasy
Pages: 1040-1044
Published online: 13 Sep 2010
AbstractforNormal Tissue Complication Probability (NTCP) modeling of late rectal bleeding following external beam radiotherapy for prostate cancer: A Test of the QUANTEC-recommended NTCP model | Full Text | References | PDF (184.8 KB)
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Article
Evaluation of adaptive radiotherapy of bladder cancer by image-based tumour control probability modelling
Pauliina Wright, Ludvig P. Muren, Morten Høyer & Eirik Malinen
Pages: 1045-1051
Published online: 13 Sep 2010
AbstractforEvaluation of adaptive radiotherapy of bladder cancer by image-based tumour control probability modelling | Full Text | References | PDF (214.3 KB)
  • 989 Views
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Article
Hypofractionation does not increase radiation pneumonitis risk with modern conformal radiation delivery techniques
Ivan S. Vogelius, David C. Westerly, George M. Cannon & Søren M. Bentzen
Pages: 1052-1057
Published online: 13 Sep 2010
AbstractforHypofractionation does not increase radiation pneumonitis risk with modern conformal radiation delivery techniques | Full Text | References | PDF (361.1 KB)
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Letter to the Editor

Letter
Cardiac toxicity and radiation dose to the heart in definitive treated non-small cell lung cancer
Tine Schytte, Olfred Hansen, Thomine Stolberg-Rohr & Carsten Brink
Pages: 1058-1060
Published online: 13 Sep 2010
First Page PreviewforCardiac toxicity and radiation dose to the heart in definitive treated non-small cell lung cancer | Full Text | References | PDF (84.3 KB)
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Original Article

Article
Rectum motion and morbidity prediction: Improving correlation between late morbidity and DVH parameters through use of rectum planning organ at risk volumes
Maria Thor, Michael Væth, Ása Karlsdottir & Ludvig Paul Muren
Pages: 1061-1068
Published online: 13 Sep 2010
AbstractforRectum motion and morbidity prediction: Improving correlation between late morbidity and DVH parameters through use of rectum planning organ at risk volumes | Full Text | References | PDF (213.3 KB)
  • 918 Views
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Research Article

Article
A comparison of three different adaptive strategies in image-guided radiotherapy of bladder cancer
Anne Vestergaard, Jimmi Søndergaard, Jørgen B. Petersen, Morten Høyer & Ludvig Paul Muren
Pages: 1069-1076
Published online: 13 Sep 2010
AbstractforA comparison of three different adaptive strategies in image-guided radiotherapy of bladder cancer | Full Text | References | PDF (219 KB)
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Article
Daily cone-beam computed tomography used to determine tumour shrinkage and localisation in lung cancer patients
Marianne Marquard Knap, Lone Hoffmann, Marianne Nordsmark & Anne Vestergaard
Pages: 1077-1084
Published online: 13 Sep 2010
AbstractforDaily cone-beam computed tomography used to determine tumour shrinkage and localisation in lung cancer patients | Full Text | References | PDF (185.1 KB)
  • 2125 Views
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Article
Clinical evaluation of 3D/3D MRI-CBCT automatching on brain tumors for online patient setup verification – A step towards MRI-based treatment planning
Sune K. Buhl, Anne K. Duun-Christensen, Brian H. Kristensen & Claus F. Behrens
Pages: 1085-1091
Published online: 13 Sep 2010
AbstractforClinical evaluation of 3D/3D MRI-CBCT automatching on brain tumors for online patient setup verification – A step towards MRI-based treatment planning | Full Text | References | PDF (176.7 KB)
  • 1149 Views
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Article
Dynamic MLC tracking of moving targets with a single kV imager for 3D conformal and IMRT treatments
Per R. Poulsen, Byungchul Cho, Amit Sawant, Dan Ruan & Paul J. Keall
Pages: 1092-1100
Published online: 13 Sep 2010
AbstractforDynamic MLC tracking of moving targets with a single kV imager for 3D conformal and IMRT treatments | Full Text | References | PDF (466.5 KB)
  • 1018 Views
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Article
Daily kV cone-beam CT and deformable image registration as a method for studying dosimetric consequences of anatomic changes in adaptive IMRT of head and neck cancer
Ulrik V. Elstrøm, Barbara A. Wysocka, Ludvig P. Muren, Jørgen B.B. Petersen & Cai Grau
Pages: 1101-1108
Published online: 13 Sep 2010
AbstractforDaily kV cone-beam CT and deformable image registration as a method for studying dosimetric consequences of anatomic changes in adaptive IMRT of head and neck cancer | Full Text | References | PDF (506.3 KB)
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Article
A study of image-guided radiotherapy of bladder cancer based on lipiodol injection in the bladder wall
Jimmi Søndergaard, Kasper Ørding Olsen, Ludvig Paul Muren, Ulrik Vindelev Elstrøm, Cai Grau & Morten Høyer
Pages: 1109-1115
Published online: 29 Apr 2010
AbstractforA study of image-guided radiotherapy of bladder cancer based on lipiodol injection in the bladder wall | Full Text | References | PDF (188.9 KB)
  • 1485 Views
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Article
Influence of MLC leaf width on biologically adapted IMRT plans
Jan Rødal, Åste Søvik & Eirik Malinen
Pages: 1116-1123
Published online: 13 Sep 2010
AbstractforInfluence of MLC leaf width on biologically adapted IMRT plans | Full Text | References | PDF (389.1 KB)
  • 726 Views
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Commentary

Article Commentary
The role of protons in modern and biologically-guided radiotherapy
Håkan Nyström
Pages: 1124-1131
Published online: 13 Sep 2010
AbstractforThe role of protons in modern and biologically-guided radiotherapy | Full Text | References | PDF (257.7 KB)
  • 780 Views
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Original Article

Article
Heidelberg Ion Therapy Center (HIT): Initial clinical experience in the first 80 patients
Stephanie E. Combs, Malte Ellerbrock, Thomas Haberer, Daniel Habermehl, Angelika Hoess, Oliver Jäkel, Alexandra Jensen, Swantje Klemm, Marc Münter, Jakob Naumann, Anna Nikoghosyan, Susanne Oertel, Katia Parodi, Stefan Rieken & Jürgen Debus
Pages: 1132-1140
Published online: 13 Sep 2010
AbstractforHeidelberg Ion Therapy Center (HIT): Initial clinical experience in the first 80 patients | Full Text | References | PDF (329.6 KB)
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Research Article

Article
A treatment planning study of the potential of geometrical tracking for intensity modulated proton therapy of lung cancer
Per Munck Af Rosenschöld, Marianne C. Aznar, Ditte E. Nygaard, Gitte F. Persson, Stine S. Korreman, Svend Aage Engelholm & Håkan Nyström
Pages: 1141-1148
Published online: 13 Sep 2010
AbstractforA treatment planning study of the potential of geometrical tracking for intensity modulated proton therapy of lung cancer | Full Text | References | PDF (261.8 KB)
  • 864 Views
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Article
Neutron Fluence in Antiproton Radiotherapy, Measurements and Simulations
Niels Bassler, Michael H. Holzscheiter & Jørgen B. Petersen
Pages: 1149-1159
Published online: 13 Sep 2010
AbstractforNeutron Fluence in Antiproton Radiotherapy, Measurements and Simulations | Full Text | References | PDF (363.7 KB)
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Article
Investigation of the dosimetric impact of a Ni-Ti fiducial marker in carbon ion and proton beams
Rochus Herrmann, Jesper Carl, Oliver Jäkel, Niels Bassler & Jørgen B. B. Petersen
Pages: 1160-1164
Published online: 13 Sep 2010
AbstractforInvestigation of the dosimetric impact of a Ni-Ti fiducial marker in carbon ion and proton beams | Full Text | References | PDF (324.3 KB)
  • 732 Views
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Article
Dose calculation in biological samples in a mixed neutron-gamma field at the TRIGA reactor of the University of Mainz
Tobias Schmitz, Matthias Blaickner, Christian Schütz, Norbert Wiehl, Jens V. Kratz, Niels Bassler, Michael H. Holzscheiter, Hugo Palmans, Peter Sharpe, Gerd Otto & Gabriele Hampel
Pages: 1165-1169
Published online: 13 Sep 2010
AbstractforDose calculation in biological samples in a mixed neutron-gamma field at the TRIGA reactor of the University of Mainz | Full Text | References | PDF (202.9 KB)
  • 915 Views
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Article
Dose- and LET-painting with particle therapy
Niels Bassler, Oliver Jäkel, Christian Skou Søndergaard & Jørgen B. Petersen
Pages: 1170-1176
Published online: 13 Sep 2010
AbstractforDose- and LET-painting with particle therapy | Full Text | References | PDF (249.8 KB)
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Article
Inter- and intrafractional localisation errors in cone-beam CT guided stereotactic radiation therapy of tumours in the liver and lung
Esben S. Worm, Anders T. Hansen, Jørgen B. Petersen, Ludvig P. Muren, Lars H. Præstegaard & Morten Høyer
Pages: 1177-1183
Published online: 30 Jun 2010
AbstractforInter- and intrafractional localisation errors in cone-beam CT guided stereotactic radiation therapy of tumours in the liver and lung | Full Text | References | PDF (166.1 KB)
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Article
Evaluation of setup accuracy for NSCLC patients; studying the impact of different types of cone-beam CT matches based on whole thorax, columna vertebralis, and GTV
Wiviann Ottosson, Mariwan Baker, Mattias Hedman, Claus F. Behrens & David Sjöström
Pages: 1184-1191
Published online: 13 Sep 2010
AbstractforEvaluation of setup accuracy for NSCLC patients; studying the impact of different types of cone-beam CT matches based on whole thorax, columna vertebralis, and GTV | Full Text | References | PDF (251.4 KB)
  • 1981 Views
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Article
Investigation of respiration induced intra- and inter-fractional tumour motion using a standard Cone Beam CT
Karina L. Gottlieb, Christian R. Hansen, Olfred Hansen, Jonas Westberg & Carsten Brink
Pages: 1192-1198
Published online: 13 Sep 2010
AbstractforInvestigation of respiration induced intra- and inter-fractional tumour motion using a standard Cone Beam CT | Full Text | References | PDF (185.2 KB)
  • 1036 Views
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