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Research Article

Expression of ghrelin is correlated to a favorable outcome in invasive breast cancer

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Pages 386-393 | Received 09 Jun 2011, Accepted 01 Oct 2011, Published online: 09 Nov 2011

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Sheren Fouad Younes, Hayam Aiad, Mona Kandil & Fatma Samir El Kalashy. (2015) Expression and Clinical Significance of Ghrelin in Endometrial Hyperplasia and Carcinoma of Egyptian Patients. Ultrastructural Pathology 39:3, pages 207-213.
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Maria Angela Guzzardi, Gabriella Pugliese, Filomena Bottiglieri, Caterina Pelosini, Giovanna Muscogiuri, Luigi Barrea, Silvia Savastano & Annamaria Colao. (2021) Obesity-related gut hormones and cancer: novel insight into the pathophysiology. International Journal of Obesity 45:9, pages 1886-1898.
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Irene Spiridon, Delia Ciobanu, Simona Giușcă & Irina Căruntu. (2021) Ghrelin and its role in gastrointestinal tract tumors (Review). Molecular Medicine Reports 24:3.
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Berna SARUHAN, Hakan SAĞSÖZ & Uğur TOPALOĞLU. (2020) Sıçanların Meme Dokusunda Gebelik, Laktasyon ve İnvolusyon Periyodları Süresince Ghrelin, Obestatin ve Leptin Dağılımı. Dicle Üniversitesi Veteriner Fakültesi Dergisi 13:2, pages 166-171.
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CheukMan C Au, John B Furness, Kara Britt, Sofya Oshchepkova, Heta Ladumor, Kai Ying Soo, Brid Callaghan, Celine Gerard, Giorgio Inghirami, Vivek Mittal, Yufeng Wang, Xin Yun Huang, Jason A Spector, Eleni Andreopoulou, Paul Zumbo, Doron Betel, Lukas Dow & Kristy A Brown. (2020) Three-dimensional growth of breast cancer cells potentiates the anti-tumor effects of unacylated ghrelin and AZP-531. eLife 9.
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Saeed Soleyman-Jahi, Fatemeh Sadeghi, Amin Pastaki Khoshbin, Leila Khani, Venus Roosta & Kazem Zendehdel. (2019) Attribution of Ghrelin to Cancer; Attempts to Unravel an Apparent Controversy. Frontiers in Oncology 9.
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William H. WalkerIIII & Jeremy C. Borniger. (2019) Molecular Mechanisms of Cancer-Induced Sleep Disruption. International Journal of Molecular Sciences 20:11, pages 2780.
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Malin Grönberg, Cecilia Nilsson, Ida Markholm, Ingrid Hedenfalk, Carl Blomqvist, Lars Holmberg, Eva Tiensuu Janson & Marie-Louise Fjällskog. (2018) Ghrelin expression is associated with a favorable outcome in male breast cancer. Scientific Reports 8:1.
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Hanna Komarowska, Marcin Rucinski, Marianna Tyczewska, Nadia Sawicka-Gutaj, Marta Szyszka, Aleksandra Hernik, Anna Klimont, Paulina Milecka, Laura Migasiuk, Mateusz Biczysko, Ilona Idasiak-Piechocka, Marek Karczewski & Marek Ruchala. (2018) Ghrelin as a potential molecular marker of adrenal carcinogenesis: In vivo and in vitro evidence. Clinical Endocrinology 89:1, pages 36-45.
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David Rincón-Fernández, Michael D Culler, Natia Tsomaia, Gema Moreno-Bueno, Raúl M Luque, Manuel D Gahete & Justo P Castaño. (2018) In1-ghrelin splicing variant is associated with reduced disease-free survival of breast cancer patients and increases malignancy of breast cancer cells lines. Carcinogenesis 39:3, pages 447-457.
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Malin Grönberg, Cecilia Ahlin, Ylva Naeser, Eva Tiensuu Janson, Lars Holmberg & Marie-Louise Fjällskog. (2017) Ghrelin is a prognostic marker and a potential therapeutic target in breast cancer. PLOS ONE 12:4, pages e0176059.
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CheukMan Cherie Au, John B. Furness & Kristy A. Brown. (2017) Ghrelin and Breast Cancer: Emerging Roles in Obesity, Estrogen Regulation, and Cancer. Frontiers in Oncology 6.
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Saeed Soleyman-Jahi, Afshin Abdirad, Amir Afraz Fallah, Sevil Ghasemi, Fatemeh Sadeghi, Reza Heidari, Habibollah Mahmoodzadeh & Kazem Zendehdel. (2017) Prognostic Significance of Preoperative and Postoperative Plasma Levels of Ghrelin in Gastric Cancer: 3-Year Survival Study. Clinical and Translational Gastroenterology 8:1, pages e209.
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Roni Allaoui, Caroline Bergenfelz, Sofie Mohlin, Catharina Hagerling, Kiarash Salari, Zena Werb, Robin L. Anderson, Stephen P. Ethier, Karin Jirström, Sven Påhlman, Daniel Bexell, Balázs Tahin, Martin E. Johansson, Christer Larsson & Karin Leandersson. (2016) Cancer-associated fibroblast-secreted CXCL16 attracts monocytes to promote stroma activation in triple-negative breast cancers. Nature Communications 7:1.
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Andrew J. Pellatt, Abbie Lundgreen, Roger K. Wolff, Lisa Hines, Esther M. John & Martha L. Slattery. (2015) Energy homeostasis genes and survival after breast cancer diagnosis: the Breast Cancer Health Disparities Study. Cancer Causes & Control 27:1, pages 47-57.
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Meliha Mehmeti, Roni Allaoui, Caroline Bergenfelz, Lao H. Saal, Stephen P. Ethier, Martin E. Johansson, Karin Jirström & Karin Leandersson. (2015) Expression of functional toll like receptor 4 in estrogen receptor/progesterone receptor-negative breast cancer. Breast Cancer Research 17:1.
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Caroline Bergenfelz, Alexander Gaber, Roni Allaoui, Meliha Mehmeti, Karin Jirström, Tomas Leanderson & Karin Leandersson. (2015) S100A9 expressed in ER−PgR− breast cancers induces inflammatory cytokines and is associated with an impaired overall survival. British Journal of Cancer 113:8, pages 1234-1243.
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Xuyi Wang, Evan R. Simpson & Kristy A. Brown. (2015) Aromatase overexpression in dysfunctional adipose tissue links obesity to postmenopausal breast cancer. The Journal of Steroid Biochemistry and Molecular Biology 153, pages 35-44.
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JUNWEN WANG, SONGBO GUO, LIN HAN, MINGBO FANG, LEI WANG, JÖRG W. BARTSCH & JUN LI. (2015) Correlation of ghrelin and growth hormone secretagogue receptor expression with clinical features in human pituitary adenomas. Experimental and Therapeutic Medicine 9:5, pages 1909-1914.
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Aleksandra Matuszyk, Dagmara Ceranowicz, Zygmunt Warzecha, Piotr Ceranowicz, Krzysztof Fyderek, Krystyna Gałązka, Jakub Cieszkowski, Joanna Bonior, Jolanta Jaworek, Małgorzata Pihut & Artur Dembiński. (2015) The Influence of Ghrelin on the Development of Dextran Sodium Sulfate-Induced Colitis in Rats. BioMed Research International 2015, pages 1-9.
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Brid Callaghan & John B. Furness. (2014) Novel and Conventional Receptors for Ghrelin, Desacyl-Ghrelin, and Pharmacologically Related Compounds. Pharmacological Reviews 66:4, pages 984-1001.
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Maria M. Docanto, Fangyuan Yang, Brid Callaghan, CheukMan C. Au, Rahini Ragavan, Xuyi Wang, John B. Furness, Zane B. Andrews & Kristy A. Brown. (2014) Ghrelin and des-acyl ghrelin inhibit aromatase expression and activity in human adipose stromal cells: suppression of cAMP as a possible mechanism. Breast Cancer Research and Treatment 147:1, pages 193-201.
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Chuang Tian, Lianhai Zhang, Daohu Hu & Jiafu Ji. (2013) Ghrelin induces gastric cancer cell proliferation, migration, and invasion through GHS-R/NF-κB signaling pathway. Molecular and Cellular Biochemistry 382:1-2, pages 163-172.
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Sara Pellegrino, Massimiliano Ruscica, Paolo Magni, Giulio Vistoli & Maria Luisa Gelmi. (2013) Antiproliferative activity on human prostate carcinoma cell lines of new peptidomimetics containing the spiroazepinoindolinone scaffold. Bioorganic & Medicinal Chemistry 21:17, pages 5470-5479.
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Lisa K. Chopin, Inge Seim, Carina M. Walpole & Adrian C. Herington. (2012) The Ghrelin Axis—Does It Have an Appetite for Cancer Progression?. Endocrine Reviews 33:6, pages 849-891.
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