2,955
Views
49
CrossRef citations to date
0
Altmetric
Original Articles

Proton and carbon ion radiotherapy for primary brain tumors and tumors of the skull base

, , , , &
Pages 1504-1509 | Received 21 May 2013, Accepted 13 Jun 2013, Published online: 21 Aug 2013

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (3)

Johannes Müller, Christian Neubert, Cläre von Neubeck, Michael Baumann, Mechthild Krause, Wolfgang Enghardt, Rebecca Bütof, Antje Dietrich & Armin Lühr. (2017) Proton radiography for inline treatment planning and positioning verification of small animals. Acta Oncologica 56:11, pages 1399-1405.
Read now
Cai Grau, Jens Overgaard, Morten Høyer, Kari Tanderup, Jacob Christian Lindegaard & Ludvig Paul Muren. (2015) Biology-guided adaptive radiotherapy (BiGART) is progressing towards clinical reality. Acta Oncologica 54:9, pages 1245-1250.
Read now
Brita S. Sørensen, Michael R. Horsman, Jan Alsner, Jens Overgaard, Marco Durante, Michael Scholz, Thomas Friedrich & Niels Bassler. (2015) Relative biological effectiveness of carbon ions for tumor control, acute skin damage and late radiation-induced fibrosis in a mouse model. Acta Oncologica 54:9, pages 1623-1630.
Read now

Articles from other publishers (46)

Alexander Helm & Claudia Fournier. (2023) High-LET charged particles: radiobiology and application for new approaches in radiotherapy. Strahlentherapie und Onkologie 199:12, pages 1225-1241.
Crossref
Xianxin Qiu, Jing Gao, Jiyi Hu, Jing Yang, Weixu Hu, Qingting Huang, Haojiong Zhang, Jiade J. Lu & Lin Kong. (2023) Particle beam radiotherapy in the treatment of WHO grade 2 and 3 meningiomas: an early experience from Shanghai Proton and Heavy Ion Center. Journal of Neuro-Oncology 165:2, pages 241-250.
Crossref
Raffaella De Pietro, Lucy Zaccaro, Francesco Marampon, Paolo Tini, Francesca De Felice & Giuseppe Minniti. (2023) The evolving role of reirradiation in the management of recurrent brain tumors. Journal of Neuro-Oncology.
Crossref
Alberto Iannalfi, Giulia Riva, Lucia Ciccone & Ester Orlandi. (2023) The role of particle radiotherapy in the treatment of skull base tumors. Frontiers in Oncology 13.
Crossref
Lorenzo Vagnoni, Sami Aburas, Martina Giraffa, Ivana Russo, Vito Chiarella, Sergio Paolini, Paolo Tini & Giuseppe Minniti. (2022) Radiation therapy for atypical and anaplastic meningiomas: an overview of current results and controversial issues. Neurosurgical Review 45:5, pages 3019-3033.
Crossref
Ruirui Liu, Xiandong Zhao & Maria Medrano. (2022) Experimental validation of proton physics models of Geant4 for calculating stopping power ratio. Journal of Radiological Protection 42:2, pages 021530.
Crossref
Dr. Kim Melanie Kraus & Univ. Prof. Dr. Stephanie E. Combs. 2022. Principles and Practice of Particle Therapy. Principles and Practice of Particle Therapy 225 237 .
Raees TonseMDMD, Pouya SabouriPhDPhD, Minesh P. MehtaMDMD & Rupesh KotechaMDMD. 2022. Principles and Practice of Particle Therapy. Principles and Practice of Particle Therapy 177 199 .
Laura Ghesquière‐Diérickx, Renato Félix‐Bautista, Annika Schlechter, Laurent Kelleter, Marvin Reimold, Gernot Echner, Pavel Soukup, Oliver Jäkel, Tim Gehrke & Maria Martišíková. (2022) Detecting perturbations of a radiation field inside a head‐sized phantom exposed to therapeutic carbon‐ion beams through charged‐fragment tracking. Medical Physics 49:3, pages 1776-1792.
Crossref
Milena Simovic, Michiel Bolkestein, Mahmoud Moustafa, John K L Wong, Verena Körber, Sarah Benedetto, Umar Khalid, Hannah Sophia Schreiber, Manfred Jugold, Andrey Korshunov, Daniel Hübschmann, Norman Mack, Stephan Brons, Pei-Chi Wei, Michael O Breckwoldt, Sabine Heiland, Martin Bendszus, Jürgen Debus, Thomas Höfer, Marc Zapatka, Marcel Kool, Stefan M Pfister, Amir Abdollahi & Aurélie Ernst. (2021) Carbon ion radiotherapy eradicates medulloblastomas with chromothripsis in an orthotopic Li-Fraumeni patient-derived mouse model. Neuro-Oncology 23:12, pages 2028-2041.
Crossref
Guang Ma, Bingxin Gu, Jiyi Hu, Lin Kong, Jiangang Zhang, Zili Li, Yangbo Xue, Jiade Lu, Junning Cao, Jingyi Cheng, Yingjian Zhang, Shaoli Song & Zhongyi Yang. (2021) Pretreatment 18F-FDG uptake heterogeneity can predict treatment outcome of carbon ion radiotherapy in patients with locally recurrent nasopharyngeal carcinoma. Annals of Nuclear Medicine 35:7, pages 834-842.
Crossref
Jie-yun Li, Jing-wen Li, Yuan-chang Jin, Mei-xuan Li, Li-ping Guo, Zhi-tong Bing, Qiu-ning Zhang, Fei Bai, Xiao-hu Wang, Xiu-xia Li & Ke-hu Yang. (2021) The Efficacy and Safety of Carbon Ion Radiotherapy for Meningiomas: A Systematic Review and Meta-Analysis. Frontiers in Oncology 11.
Crossref
Ruirui Liu, Baozhou Sun, Tiezhi Zhang, Jeffery F. Williamson, Joseph A. O’Sullivan & Tianyu Zhao. (2021) Dosimetric impact of range uncertainty in passive scattering proton therapy. Journal of Applied Clinical Medical Physics 22:5, pages 6-14.
Crossref
Almut Dutz, Armin Lühr, Linda Agolli, Rebecca Bütof, Chiara Valentini, Esther G.C. Troost, Michael Baumann, Xavier Vermeren, Dirk Geismar, Nayan Lamba, Emily S. Lebow, Meghan Bussière, Jillian E. Daly, Marc R. Bussière, Mechthild Krause, Beate Timmermann, Helen A. Shih & Steffen Löck. (2021) Modelling of late side-effects following cranial proton beam therapy. Radiotherapy and Oncology 157, pages 15-23.
Crossref
William C. Stross, Timothy D. Malouff, Mark R. Waddle, Robert C. Miller, Jennifer Peterson & Daniel M. Trifiletti. (2020) Proton beam therapy utilization in adults with primary brain tumors in the United States. Journal of Clinical Neuroscience 75, pages 112-116.
Crossref
Heike Thomas & Beate Timmermann. (2020) Paediatric proton therapy. The British Journal of Radiology 93:1107, pages 20190601.
Crossref
Timothy D. Malouff, Anita Mahajan, Sunil Krishnan, Chris Beltran, Danushka S. Seneviratne & Daniel Michael Trifiletti. (2020) Carbon Ion Therapy: A Modern Review of an Emerging Technology. Frontiers in Oncology 10.
Crossref
Jac A. Nickoloff, Neelam Sharma & Lynn Taylor. (2020) Clustered DNA Double-Strand Breaks: Biological Effects and Relevance to Cancer Radiotherapy. Genes 11:1, pages 99.
Crossref
David G. BrachmanEmad YoussefChristopher J. Dardis, Nader Sanai, Joseph M. Zabramski, Kris A. Smith, Andrew S. Little, Andrew G. Shetter, Theresa Thomas, Heyoung L. McBride, Stephen Sorensen, Robert F. Spetzler & Peter Nakaji. (2019) Resection and permanent intracranial brachytherapy using modular, biocompatible cesium-131 implants: results in 20 recurrent, previously irradiated meningiomas. Journal of Neurosurgery 131:6, pages 1819-1828.
Crossref
William S. Coggins, Nguyen K. Pham, Anthony V. Nguyen, Daniel W. Branch, June Y. Guillet, Genevieve Korst & Rishi R. Lall. (2019) A Systematic Review of Ion Radiotherapy in Maintaining Local Control Regarding Atypical and Anaplastic Meningiomas. World Neurosurgery 132, pages 282-291.
Crossref
Timothy D. Malouff, Jennifer L. Peterson, Anita Mahajan & Daniel M. Trifiletti. (2019) Carbon ion radiotherapy in the treatment of gliomas: a review. Journal of Neuro-Oncology 145:2, pages 191-199.
Crossref
Adela WuMichael C. Jin, Antonio MeolaHong-nei Wong & Steven D. Chang. (2019) Efficacy and toxicity of particle radiotherapy in WHO grade II and grade III meningiomas: a systematic review. Neurosurgical Focus 46:6, pages E12.
Crossref
Christin Glowa, Peter Peschke, Stephan Brons, Jürgen Debus & Christian P. Karger. (2019) Intrinsic and extrinsic tumor characteristics are of minor relevance for the efficacy of split-dose carbon ion irradiation in three experimental prostate tumors. Radiotherapy and Oncology 133, pages 120-124.
Crossref
Almut Dutz, Armin Lühr, Linda Agolli, Esther G.C. Troost, Mechthild Krause, Michael Baumann, Xavier Vermeren, Dirk Geismar, Emily F. Schapira, Meghan Bussière, Jillian E. Daly, Marc R. Bussière, Beate Timmermann, Helen A. Shih & Steffen Löck. (2019) Development and validation of NTCP models for acute side-effects resulting from proton beam therapy of brain tumours. Radiotherapy and Oncology 130, pages 164-171.
Crossref
Falk Stade, Jan-Oliver Dittmar, Oliver Jäkel, Clemens Kratochwil, Uwe Haberkorn, Jürgen Debus & Stephanie E. Combs. (2018) Influence of 68Ga-DOTATOC on sparing of normal tissue for radiation therapy of skull base meningioma: differential impact of photon and proton radiotherapy. Radiation Oncology 13:1.
Crossref
Erik Thurin, Petra W. Nyström, Anja Smits, Katja Werlenius, Anna Bäck, Ann Liljegren, Eva-Lotte Daxberg & Asgeir Store Jakola. (2018) Proton therapy for low-grade gliomas in adults: A systematic review. Clinical Neurology and Neurosurgery 174, pages 233-238.
Crossref
M. Wank, D. Schilling, J. Reindl, B. Meyer, J. Gempt, S. Motov, F. Alexander, J. J. Wilkens, J. Schlegel, T. E. Schmid & S. E. Combs. (2018) Evaluation of radiation-related invasion in primary patient-derived glioma cells and validation with established cell lines: impact of different radiation qualities with differing LET. Journal of Neuro-Oncology 139:3, pages 583-590.
Crossref
Andrew Orton, Jonathan Frandsen, Randy Jensen, Dennis C. Shrieve & Gita Suneja. (2018) Anaplastic meningioma: an analysis of the National Cancer Database from 2004 to 2012. Journal of Neurosurgery 128:6, pages 1684-1689.
Crossref
Stephanie E. Combs, Mostafa Farzin, Julia Boehmer, Oliver Oehlke, Michael Molls, Jürgen Debus & Anca-Ligia Grosu. (2018) Clinical outcome after high-precision radiotherapy for skull base meningiomas: Pooled data from three large German centers for radiation oncology. Radiotherapy and Oncology 127:2, pages 274-279.
Crossref
J. Biau, T. Khalil, P. Verrelle & J.-J. Lemaire. (2018) Fractionated radiotherapy and radiosurgery of intracranial meningiomas. Neurochirurgie 64:1, pages 29-36.
Crossref
Christoph Straube & Stephanie E. Combs. (2017) Stellenwert der Strahlentherapie bei sezernierenden und nichtsezernierenden HypophysenadenomenImportance of radiotherapy for treatment of secreting and non-secreting pituitary adenomas. Der Onkologe 24:2, pages 143-150.
Crossref
Yolanda D. Tseng & Lia Halasz. 2018. Principles of Neurological Surgery. Principles of Neurological Surgery 736 744.e3 .
Sebastian Adeberg, Semi B. Harrabi, Vivek Verma, Denise Bernhardt, Nicole Grau, Jürgen Debus & Stefan Rieken. (2017) Treatment of meningioma and glioma with protons and carbon ions. Radiation Oncology 12:1.
Crossref
Florian Ringel, Yu-Mi Ryang, Jan S. Kirschke, Birgit S. M?ller, Jan J. Wilkens, Jeremy Brodard, Stephanie E. Combs & Bernhard Meyer. (2017) Radiolucent Carbon Fiber?Reinforced Pedicle Screws for Treatment of Spinal Tumors: Advantages for Radiation Planning and Follow-Up Imaging. World Neurosurgery 105, pages 294-301.
Crossref
Stephanie E. Combs. (2017) Does Proton Therapy Have a Future in CNS Tumors?. Current Treatment Options in Neurology 19:3.
Crossref
Sâmia Yasin Wayhs, Guilherme Alves Lepski, Leonardo Frighetto & Gustavo Rassier Isolan. (2017) Petroclival meningiomas: Remaining controversies in light of minimally invasive approaches. Clinical Neurology and Neurosurgery 152, pages 68-75.
Crossref
Kristin Astrid Øystese, Johan Arild Evang & Jens Bollerslev. (2016) Non-functioning pituitary adenomas: growth and aggressiveness. Endocrine 53:1, pages 28-34.
Crossref
Terry C. BurnsAhmed J. Awad, Matthew D. Li & Gerald A. Grant. (2016) Radiation-induced brain injury: low-hanging fruit for neuroregeneration. Neurosurgical Focus 40:5, pages E3.
Crossref
Alfredo Conti & Antonio Pontoriero. 2016. Midline Skull Base Surgery. Midline Skull Base Surgery 269 279 .
Fei Ye, Ting Zhao, Xiongxiong Liu, Xiaodong Jin, Xinguo Liu, Tieshan Wang & Qiang Li. (2015) Long-term Autophagy and Nrf2 Signaling in the Hippocampi of Developing Mice after Carbon Ion Exposure. Scientific Reports 5:1.
Crossref
Runhong Lei, Tuo Zhao, Qiang Li, Xiao Wang, Hong Ma & Yulin Deng. (2015) Carbon Ion Irradiated Neural Injury Induced the Peripheral Immune Effects in Vitro or in Vivo. International Journal of Molecular Sciences 16:12, pages 28334-28346.
Crossref
Kengo Ohta, Masashi Shimohira, Shigeru Sasaki, Hiromitsu Iwata, Hiroko Nishikawa, Hiroyuki Ogino, Masaki Hara, Takuya Hashizume & Yuta Shibamoto. (2014) Transarterial Fiducial Marker Placement for Image-guided Proton Therapy for Malignant Liver Tumors. CardioVascular and Interventional Radiology 38:5, pages 1288-1293.
Crossref
Florian Simon, Jan-Oliver Dittmar, Stephan Brons, Lena Orschiedt, Steffi Urbschat, Klaus-Josef Weber, Jürgen Debus, Stephanie E. Combs & Stefan Rieken. (2014) Integrin-based meningioma cell migration is promoted by photon but not by carbon-ion irradiationFörderung der integrinbasierten Meningeomzellmigration durch Bestrahlung mit Photonen, nicht jedoch durch Bestrahlung mit Kohlenstoffionen. Strahlentherapie und Onkologie 191:4, pages 347-355.
Crossref
Sam Q. Sun, Ammar H. Hawasli, Jiayi Huang, Michael R. Chicoine & Albert H. Kim. (2015) An evidence-based treatment algorithm for the management of WHO Grade II and III meningiomas. Neurosurgical Focus 38:3, pages E3.
Crossref
Ron R Allison, Rajen M Patel & Robert A McLawhorn. (2014) Radiation oncology: physics advances that minimize morbidity. Future Oncology 10:15, pages 2329-2344.
Crossref
Kerstin A. Kessel, Christian Bohn, Uwe Engelmann, Dieter Oetzel, Nina Bougatf, Rolf Bendl, Jürgen Debus & Stephanie E. Combs. (2014) Five-year experience with setup and implementation of an integrated database system for clinical documentation and research. Computer Methods and Programs in Biomedicine 114:2, pages 206-217.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.