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Research Article

Modulation of Quinol/Quinone-Thioether Toxicity by Intramolecular Detoxication

Pages 93-106 | Published online: 22 Sep 2008

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J. Shang, S. Xu, Y. Teffera, G. A. Doss, R. A. Stearns, S. Edmonson & M. G. Beconi. (2005) Metabolic activation of a pentafluorophenylethylamine derivative: Formation of glutathione conjugates in vitro in the rat. Xenobiotica 35:7, pages 697-713.
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Fengjiao Zhang, Frances M. Munoz, Lanlan Sun, Shuya Zhang, Serrine S. Lau & Terrence J. Monks. (2019) Cell-specific regulation of Nrf2 during ROS-Dependent cell death caused by 2,3,5-tris(glutathion-S-yl)hydroquinone (TGHQ). Chemico-Biological Interactions 302, pages 1-10.
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Yoshito Kumagai, Yasuhiro Shinkai, Takashi Miura & Arthur K. Cho. (2012) The Chemical Biology of Naphthoquinones and Its Environmental Implications. Annual Review of Pharmacology and Toxicology 52:1, pages 221-247.
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. 2002. The MAK-Collection for Occupational Health and Safety. The MAK-Collection for Occupational Health and Safety 1 318 .
. 2002. The MAK‐Collection for Occupational Health and Safety. The MAK‐Collection for Occupational Health and Safety 1 26 .
Fengjiao Zhang, Serrine S. Lau & Terrence J. Monks. (2011) The Cytoprotective Effect of N-acetyl-L-cysteine against ROS-Induced Cytotoxicity Is Independent of Its Ability to Enhance Glutathione Synthesis. Toxicological Sciences 120:1, pages 87-97.
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John C. L. Erve, Mats A. Svensson, Hans von Euler-Chelpin & Eva Klasson-Wehler. (2004) Characterization of Glutathione Conjugates of the Remoxipride Hydroquinone Metabolite NCQ-344 Formed in Vitro and Detection following Oxidation by Human Neutrophils. Chemical Research in Toxicology 17:4, pages 564-571.
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Hanem M. Awad, Marelle G. Boersma, Sjef Boeren, Peter J. van Bladeren, Jacques Vervoort & Ivonne M. C. M. Rietjens. (2003) Quenching of Quercetin Quinone/Quinone Methides by Different Thiolate Scavengers:  Stability and Reversibility of Conjugate Formation. Chemical Research in Toxicology 16:7, pages 822-831.
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Carmen Alt & Peter Eyer. (1998) Ring Addition of the α-Amino Group of Glutathione Increases the Reactivity of Benzoquinone Thioethers. Chemical Research in Toxicology 11:10, pages 1223-1233.
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Phillip R. Jefferies, Gary B. Quistad & John E. Casida. (1998) Dialkylquinonimines Validated as in Vivo Metabolites of Alachlor, Acetochlor, and Metolachlor Herbicides in Rats. Chemical Research in Toxicology 11:4, pages 353-359.
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Terrence J. Monks & Serrine S. Lau. (1997) Biological Reactivity of Polyphenolic−Glutathione Conjugates. Chemical Research in Toxicology 10:12, pages 1296-1313.
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