1,155
Views
46
CrossRef citations to date
0
Altmetric
Review Article

Nanostructure-based drug delivery systems for brain targeting

, , , , &
Pages 387-411 | Received 21 Mar 2011, Accepted 22 Jul 2011, Published online: 28 Sep 2011

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (11)

Saikat Ghosh, Rohan Lalani, Vivek Patel, Subhas Bhowmick & Ambikanandan Misra. (2019) Surface engineered liposomal delivery of therapeutics across the blood brain barrier: recent advances, challenges and opportunities. Expert Opinion on Drug Delivery 16:12, pages 1287-1311.
Read now
Ravisankar Vanka, Gowthamarajan Kuppusamy, Simhadri Praveen Kumar, Uday Krishna Baruah, Veera Venkata Satyanarayana Reddy Karri, Vimal Pandey & Phanithi Prakash Babu. (2018) Ameliorating the in vivo antimalarial efficacy of artemether using nanostructured lipid carriers. Journal of Microencapsulation 35:2, pages 121-136.
Read now
Oscar Escalona-Rayo, Paulina Fuentes-Vázquez, Gerardo Leyva-Gómez, Bulmaro Cisneros, Rafael Villalobos, Jonathan J. Magaña & David Quintanar-Guerrero. (2017) Nanoparticulate strategies for the treatment of polyglutamine diseases by halting the protein aggregation process. Drug Development and Industrial Pharmacy 43:6, pages 871-888.
Read now
Yanzhi Song, Jie Han, Rui Feng, Mengjing Wang, Qingjing Tian, Ting Zhang, Xinrong Liu, Xiaobo Cheng & Yihui Deng. (2016) The 12-3-12 cationic gemini surfactant as a novel gastrointestinal bioadhesive material for improving the oral bioavailability of coenzyme Q10 naked nanocrystals. Drug Development and Industrial Pharmacy 42:12, pages 2044-2054.
Read now
Prabhjot Kaur, Tarun Garg, Goutam Rath & Amit K. Goyal. (2016) In situ nasal gel drug delivery: A novel approach for brain targeting through the mucosal membrane. Artificial Cells, Nanomedicine, and Biotechnology 44:4, pages 1167-1176.
Read now
Bruno Fonseca-Santos, Maria Palmira Daflon Gremião & Marlus Chorilli. (2015) Nanotechnology-based drug delivery systems for the treatment of Alzheimer’s disease. International Journal of Nanomedicine 10, pages 4981-5003.
Read now
Xiu-Rong Zhang, Nian-Qiu Shi, Yang Zhao, He-Yun Zhu, Jiao Guan & Ying Jin. (2015) Deoxycholic acid-grafted PEGylated chitosan micelles for the delivery of mitomycin C. Drug Development and Industrial Pharmacy 41:6, pages 916-926.
Read now
Jian-Sheng Liu, Jian-Hong Wang, Jie Zhou, Xing-Hua Tang, Lan Xu, Teng Shen, Xun-Yi Wu & Zhen Hong. (2014) Enhanced brain delivery of lamotrigine with Pluronic® P123-based nanocarrier. International Journal of Nanomedicine 9, pages 3923-3935.
Read now
Shadab Md, Mushir Ali, Sanjula Baboota, Jasjeet Kaur Sahni, Aseem Bhatnagar & Javed Ali. (2014) Preparation, characterization, in vivo biodistribution and pharmacokinetic studies of donepezil-loaded PLGA nanoparticles for brain targeting. Drug Development and Industrial Pharmacy 40:2, pages 278-287.
Read now
Jianmin Wang, Jinguo Tang, Xuefeng Zhou & Qiang Xia. (2014) Physicochemical characterization, identification and improved photo-stability of alpha-lipoic acid-loaded nanostructured lipid carrier. Drug Development and Industrial Pharmacy 40:2, pages 201-210.
Read now
Changhai Qu, Jian Ni, Pei Yang, Hui Zhang, Longfei Lin, Jiang Li, Jingchen Tian, Jing Fu, Xingbin Yin & Hui Kong. (2013) Altered plasma and brain disposition of isopropylidene shikimic acid liposome in rats and the brain protection in cerebral ischemia–reperfusion. Drug Development and Industrial Pharmacy 39:9, pages 1291-1295.
Read now

Articles from other publishers (35)

Utsav Gupta & Shaheen Sultana. (2023) Pegylated Nanoparticles for Brain Targeting- Opportunities and Challenges. Current Nanomedicine 13:3, pages 199-209.
Crossref
Ljubica Mihailova, Dushko Shalabalija, Andreas Zimmer, Nikola Geskovski, Petre Makreski, Marija Petrushevska, Maja Simonoska Crcarevska & Marija Glavas Dodov. (2023) Comparative Studies of the Uptake and Internalization Pathways of Different Lipid Nano-Systems Intended for Brain Delivery. Pharmaceutics 15:8, pages 2082.
Crossref
Emile F. van Vliet, Maarten J. Knol, Raymond M. Schiffelers, Massimiliano Caiazzo & Marcel H.A.M. Fens. (2023) Levodopa-loaded nanoparticles for the treatment of Parkinson's disease. Journal of Controlled Release 360, pages 212-224.
Crossref
Mohammad Sameer Khan, Sradhanjali Mohapatra, Vaibhav Gupta, Ahsan Ali, Punnoth Poonkuzhi Naseef, Mohamed Saheer Kurunian, Abdulkhaliq Ali F. Alshadidi, Md Shamsher Alam, Mohd. Aamir Mirza & Zeenat Iqbal. (2023) Potential of Lipid-Based Nanocarriers against Two Major Barriers to Drug Delivery—Skin and Blood–Brain Barrier. Membranes 13:3, pages 343.
Crossref
Md. Mominur Rhaman, Md. Rezaul Islam, Shopnil Akash, Mobasharah Mim, Md. Noor alam, Eugenie Nepovimova, Martin Valis, Kamil Kuca & Rohit Sharma. (2022) Exploring the role of nanomedicines for the therapeutic approach of central nervous system dysfunction: At a glance. Frontiers in Cell and Developmental Biology 10.
Crossref
Marta Vázquez & Pietro Fagiolino. (2021) The role of efflux transporters and metabolizing enzymes in brain and peripheral organs to explain drug‐resistant epilepsy. Epilepsia Open 7:S1.
Crossref
Zeinab Jan, Samaneh Mollazadeh, Khalil Abnous, Seyed Mohammad Taghdisi, Abolghasem Danesh, Mohammad Ramezani & Mona Alibolandi. (2022) Targeted Delivery Platforms for the Treatment of Multiple Sclerosis. Molecular Pharmaceutics 19:7, pages 1952-1976.
Crossref
Elena Markova, Lea Taneska, Monika Kostovska, Dushko Shalabalija, Ljubica Mihailova, Marija Glavas Dodov, Petre Makreski, Nikola Geskovski, Marija Petrushevska, Arben N. Taravari & Maja Simonoska Crcarevska. (2022) Design and evaluation of nanostructured lipid carriers loaded with Salvia officinalis extract for Alzheimer's disease treatment . Journal of Biomedical Materials Research Part B: Applied Biomaterials 110:6, pages 1368-1390.
Crossref
Pradeep Singh, Garima Mishra, Faheem Hyder Pottoo, Mulugeta Molla Zeleke & Amien Ewunetei. 2022. Current Thoughts on Dementia. Current Thoughts on Dementia 577 616 .
Hamdi Nsairat, Dima Khater, Fadwa Odeh, Fedaa Al-Adaileh, Suma Al-Taher, Areej M. Jaber, Walhan Alshaer, Abeer Al Bawab & Mohammad S. Mubarak. (2021) Lipid nanostructures for targeting brain cancer. Heliyon 7:9, pages e07994.
Crossref
Ana Alves, Paulo Costa, Madalena Pinto, Domingos Ferreira & Marta Correia-da-Silva. (2021) Small Molecules of Marine Origin as Potential Anti-Glioma Agents. Molecules 26:9, pages 2707.
Crossref
Farrukh Zeeshan, Dinesh Kumar Mishra & Prashant Kesharwani. 2021. Theory and Applications of Nonparenteral Nanomedicines. Theory and Applications of Nonparenteral Nanomedicines 153 180 .
Saurabh Mittal, Muhammad U. Ashhar, Farheen F. Qizilbash, Zufika Qamar, Jasjeet K. Narang, Shobhit Kumar, Javed Ali & Sanjula Baboota. (2020) Ligand Conjugated Targeted Nanotherapeutics for Treatment of Neurological Disorders. Current Pharmaceutical Design 26:19, pages 2291-2305.
Crossref
Valeria De Matteis & Loris Rizzello. (2020) Noble Metals and Soft Bio-Inspired Nanoparticles in Retinal Diseases Treatment: A Perspective. Cells 9:3, pages 679.
Crossref
Basant Salah Mahmoud, Ali Hamod AlAmri & Christopher McConville. (2020) Polymeric Nanoparticles for the Treatment of Malignant Gliomas. Cancers 12:1, pages 175.
Crossref
Vedanti R. Salvi & Pravin Pawar. (2019) Nanostructured lipid carriers (NLC) system: A novel drug targeting carrier. Journal of Drug Delivery Science and Technology 51, pages 255-267.
Crossref
Keerthi G. S. Nair, Velmurugan Ramaiyan & Sathesh Kumar Sukumaran. (2018) Enhancement of drug permeability across blood brain barrier using nanoparticles in meningitis. Inflammopharmacology 26:3, pages 675-684.
Crossref
Shadab Md, Subrat K. Bhattmisra, Farrukh Zeeshan, Naiyer Shahzad, Md Ali Mujtaba, Venkata Srikanth Meka, Ammu Radhakrishnan, Prashant Kesharwani, Sanjula Baboota & Javed Ali. (2018) Nano-carrier enabled drug delivery systems for nose to brain targeting for the treatment of neurodegenerative disorders. Journal of Drug Delivery Science and Technology 43, pages 295-310.
Crossref
Mohammed Nadim Sardoiwala, Babita Kaundal & Subhasree Roy Choudhury. 2018. Handbook of Nanomaterials for Industrial Applications. Handbook of Nanomaterials for Industrial Applications 696 709 .
Christos Tapeinos, Matteo Battaglini & Gianni Ciofani. (2017) Advances in the design of solid lipid nanoparticles and nanostructured lipid carriers for targeting brain diseases. Journal of Controlled Release 264, pages 306-332.
Crossref
Emine Sekerdag, Sevda Lüle, Sibel Bozdağ Pehlivan, Naile Öztürk, Aslı Kara, Abbas Kaffashi, Imran Vural, Ilkay Işıkay, Burҫin Yavuz, Kader Karlı Oguz, Figen Söylemezoğlu, Yasemin Gürsoy-Özdemir & Melike Mut. (2017) A potential non-invasive glioblastoma treatment: Nose-to-brain delivery of farnesylthiosalicylic acid incorporated hybrid nanoparticles. Journal of Controlled Release 261, pages 187-198.
Crossref
Abbas Kaffashi, Sevda Lüle, Sibel Bozdağ Pehlivan, Can Sarısözen, İmran Vural, Hüsnü Koşucu, Taner Demir, Kadir Emre Buğdaycı, Figen Söylemezoğlu, Kader Karlı Oğuz & Melike Mut. (2017) Farnesylthiosalicylic acid-loaded lipid–polyethylene glycol–polymer hybrid nanoparticles for treatment of glioblastoma. Journal of Pharmacy and Pharmacology 69:8, pages 1010-1021.
Crossref
Sibel Bozdağ-Pehlivan. 2017. Nanotechnology Methods for Neurological Diseases and Brain Tumors. Nanotechnology Methods for Neurological Diseases and Brain Tumors 319 344 .
Emmanuel Akala, Simeon Adesina & Oluwaseun Ogunwuyi. (2015) Computer Optimization of Biodegradable Nanoparticles Fabricated by Dispersion Polymerization. International Journal of Environmental Research and Public Health 13:1, pages 47.
Crossref
Clarence S. Yah & Geoffrey S. Simate. (2015) Nanoparticles as potential new generation broad spectrum antimicrobial agents. DARU Journal of Pharmaceutical Sciences 23:1.
Crossref
Zhongyuan Wang, Yue Zhao, Yan Jiang, Wei Lv, Lin Wu, Baoyan Wang, Lingyan Lv, Qunwei Xu & Hongliang Xin. (2015) Enhanced anti-ischemic stroke of ZL006 by T7-conjugated PEGylated liposomes drug delivery system. Scientific Reports 5:1.
Crossref
Jean–d’Amour Twibanire & T. Bruce Grindley. (2014) Polyester Dendrimers: Smart Carriers for Drug Delivery. Polymers 6:1, pages 179-213.
Crossref
Shadabul Haque, Shadab Md, Jasjeet Kaur Sahni, Javed Ali & Sanjula Baboota. (2014) Development and evaluation of brain targeted intranasal alginate nanoparticles for treatment of depression. Journal of Psychiatric Research 48:1, pages 1-12.
Crossref
Mohammad Zaki Ahmad, Sohail Akhter, Ziyaur Rahman, Javed Ahmad, Iqbal Ahmad & Farhan Jalees Ahmad. 2014. Drug Design and Discovery in Alzheimer's Disease. Drug Design and Discovery in Alzheimer's Disease 716 739 .
David Gray. 2014. Drug Delivery to the Brain. Drug Delivery to the Brain 375 397 .
Sai An, Yuyang Kuang, Teng Shen, Jianfeng Li, Haojun Ma, Yubo Guo, Xi He & Chen Jiang. (2013) Brain-targeting delivery for RNAi neuroprotection against cerebral ischemia reperfusion injury. Biomaterials 34:35, pages 8949-8959.
Crossref
Masoud Golshadi & Michael Schrlau. 2013. Carbon Nanomaterials, Second Edition. Carbon Nanomaterials, Second Edition 217 232 .
Matina Kardara, Sophia Hatziantoniou, Aggeliki Sfika, Aliki G. Vassiliou, Elena Mourelatou, Christina Μagkou, Apostolos Armaganidis, Charalambos Roussos, Stylianos E. Orfanos, Anastasia Kotanidou & Nikolaos A. Maniatis. (2013) Caveolar Uptake and Endothelial-Protective Effects of Nanostructured Lipid Carriers in Acid Aspiration Murine Acute Lung Injury. Pharmaceutical Research 30:7, pages 1836-1847.
Crossref
Massimo Masserini. (2013) Nanoparticles for Brain Drug Delivery. ISRN Biochemistry 2013, pages 1-18.
Crossref
Hongzhi Zhang, Mei Yu, Lei Xie, Linlin Jin & Zhe Yu. (2012) Carbon-Nanofibers-Based Micro-/Nanodevices for Neural-Electrical and Neural-Chemical Interfaces. Journal of Nanomaterials 2012, pages 1-6.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.