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Cancer Investigation Volume 33, 2015 - Issue 8
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ORIGINAL ARTICLE

Effect of Ang-2-VEGF-A Bispecific Antibody in Renal Cell Carcinoma

Hideharu BesshoLaboratory of Cancer Epigenome, National Cancer Centre Singapore, Singapore;Program in Cancer and Stem Cell Biology, Duke-NUS Graduate Medical School, Singapore;Department of Urology, Kitasato University School of Medicine, Kanagawa, JapanCorrespondence[email protected]
,
Bernice WongLaboratory of Cancer Epigenome, National Cancer Centre Singapore, Singapore;Program in Cancer and Stem Cell Biology, Duke-NUS Graduate Medical School, Singapore
,
Dachuan HuangLaboratory of Cancer Epigenome, National Cancer Centre Singapore, Singapore;Program in Cancer and Stem Cell Biology, Duke-NUS Graduate Medical School, Singapore
,
Jing TanLaboratory of Cancer Epigenome, National Cancer Centre Singapore, Singapore;Program in Cancer and Stem Cell Biology, Duke-NUS Graduate Medical School, Singapore
,
Choon Kiat OngLaboratory of Cancer Epigenome, National Cancer Centre Singapore, Singapore;Program in Cancer and Stem Cell Biology, Duke-NUS Graduate Medical School, Singapore
,
Masatsugu IwamuraDepartment of Urology, Kitasato University School of Medicine, Kanagawa, Japan
,
Stefan HartRoche Pharma Research & Early Development, Translational Medicine Hub, Singapore, Singapore
,
Markus DanglRoche Pharma Research & Early Development, Translational Medicine Hub, Singapore, Singapore
,
Markus ThomasRoche Diagnostics GmbH, Penzberg, Germany
&
Bin Tean TehLaboratory of Cancer Epigenome, National Cancer Centre Singapore, Singapore;Program in Cancer and Stem Cell Biology, Duke-NUS Graduate Medical School, Singapore;Cancer Science Institute of Singapore, National University of Singapore, Singapore
 show all
Pages 378-386 | Received 05 Jun 2014, Accepted 25 Apr 2015, Published online: 26 Jun 2015

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Christian Klein, Wolfgang Schaefer & Jörg T. Regula. (2016) The use of CrossMAb technology for the generation of bi- and multispecific antibodies. mAbs 8:6, pages 1010-1020.
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Articles from other publishers (9)

Na Liu, Mengfang Liu, Shengqiao Fu, Jinglei Wang, Haowen Tang, Adamu Danbala Isah, Deyu Chen & Xu Wang. (2022) Ang2-Targeted Combination Therapy for Cancer Treatment. Frontiers in Immunology 13.
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Huilin Yang, Yun‐Huai Kuo, Zion I. Smith & Jamie Spangler. (2021) Targeting cancer metastasis with antibody therapeutics. WIREs Nanomedicine and Nanobiotechnology 13:4.
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Sai Li, Qi Zhang & Yupeng Hong. (2020) Tumor Vessel Normalization: A Window to Enhancing Cancer Immunotherapy. Technology in Cancer Research & Treatment 19, pages 153303382098011.
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Gergely Solecki, Matthias Osswald, Daniel Weber, Malte Glock, Miriam Ratliff, Hans-Joachim Müller, Oliver Krieter, Yvonne Kienast, Wolfgang Wick & Frank Winkler. (2019) Differential Effects of Ang-2/VEGF-A Inhibiting Antibodies in Combination with Radio- or Chemotherapy in Glioma. Cancers 11:3, pages 314.
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Christian Klein, Wolfgang Schaefer, Joerg T. Regula, Charles Dumontet, Ulrich Brinkmann, Marina Bacac & Pablo Umaña. (2019) Engineering therapeutic bispecific antibodies using CrossMab technology. Methods 154, pages 21-31.
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Qingyuan Lv, Weijuan Zhong, Xiabin Ye, Yang Lv, Haiying Liu, Guizhen Yan & Diwen Chen. (2018) Expression of Angiopoietin and VEGF in cervical cancer and its clinical significance. Open Life Sciences 13:1, pages 527-532.
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Hai-Zhi Liu, Xiao-Xue Han, Jia Liu, Feng-Cheng Zhu & Rui-Man Li. (2017) Effect of Taoren Quyu Decoction on human endometrial cells and its anti-endometriosis activity in rats. Asian Pacific Journal of Tropical Medicine 10:7, pages 696-700.
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Ana Luísa Coelho, Mónica Patrícia Gomes, Raquel Jorge Catarino, Christian Rolfo, Agostinho Marques Lopes, Rui Manuel Medeiros & António Manuel Araújo. (2016) Angiogenesis in NSCLC: is vessel co-option the trunk that sustains the branches?. Oncotarget 8:24, pages 39795-39804.
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Lauren CJ Baker, Jessica KR Boult, Markus Thomas, Astrid Koehler, Tapan Nayak, Jean Tessier, Chia-Huey Ooi, Fabian Birzele, Anton Belousov, Magdalena Zajac, Carsten Horn, Clare LeFave & Simon P Robinson. (2016) Acute tumour response to a bispecific Ang-2-VEGF-A antibody: insights from multiparametric MRI and gene expression profiling. British Journal of Cancer 115:6, pages 691-702.
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