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Articles

Cardiovascular Risk of Resistant Hypertension: Dependence on Treatment-Time Regimen of Blood Pressure–Lowering Medications

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Pages 340-352 | Received 13 Apr 2012, Accepted 24 Apr 2012, Published online: 19 Oct 2012

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Ramón C. Hermida, Artemio Mojón, José R. Fernández, Ramón G. Hermida-Ayala, Juan J. Crespo, María T. Ríos, Manuel Domínguez-Sardiña, Alfonso Otero & Michael H. Smolensky. (2023) Elevated asleep blood pressure and non-dipper 24h patterning best predict risk for heart failure that can be averted by bedtime hypertension chronotherapy: A review of the published literature. Chronobiology International 40:1, pages 63-82.
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Ramón C. Hermida, Michael H. Smolensky, Horia Balan, Richard J. Castriotta, Juan J. Crespo, Yaron Dagan, Sherine El-Toukhy, José R. Fernández, Garret A. FitzGerald, Akio Fujimura, Yong-Jian Geng, Ramón G. Hermida-Ayala, Antonio P. Machado, Luiz Menna-Barreto, Artemio Mojón, Alfonso Otero, R. Daniel Rudic, Eva Schernhammer, Carsten Skarke, Tomoko Y. Steen, Martin E. Young & Xiaoyun Zhao. (2021) Guidelines for the design and conduct of human clinical trials on ingestion-time differences – chronopharmacology and chronotherapy – of hypertension medications. Chronobiology International 38:1, pages 1-26.
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Ramón C. Hermida, Ramón G. Hermida-Ayala, Michael H. Smolensky, Artemio Mojón & José R. Fernández. (2020) Ingestion-time – relative to circadian rhythms – differences in the pharmacokinetics and pharmacodynamics of hypertension medications. Expert Opinion on Drug Metabolism & Toxicology 16:12, pages 1159-1173.
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Ramón C. Hermida, Michael H. Smolensky, Artemio Mojón, Juan J. Crespo, María T. Ríos, Manuel Domínguez-Sardiña, Alfonso Otero & José R. Fernández. (2020) New perspectives on the definition, diagnosis, and treatment of true arterial hypertension. Expert Opinion on Pharmacotherapy 21:10, pages 1167-1178.
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Ramón C. Hermida, Artemio Mojón & José R. Fernández. (2020) Bedtime hypertension chronotherapy best reduces cardiovascular disease risk as documented by MAPEC and Hygia Chronotherapy outcomes trials. Chronobiology International 37:5, pages 731-738.
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Michael H. Smolensky, Ramon C. Hermida, Alain Reinberg, Linda Sackett-Lundeen & Francesco Portaluppi. (2016) Circadian disruption: New clinical perspective of disease pathology and basis for chronotherapeutic intervention. Chronobiology International 33:8, pages 1101-1119.
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Ramón C. Hermida, Michael H. Smolensky, Diana E. Ayala & Francesco Portaluppi. (2015) Ambulatory Blood Pressure Monitoring (ABPM) as the reference standard for diagnosis of hypertension and assessment of vascular risk in adults. Chronobiology International 32:10, pages 1329-1342.
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Ramón C. Hermida, Michael H. Smolensky, Diana E. Ayala, Francesco Portaluppi, Juan J. Crespo, Fabio Fabbian, Erhard Haus, Roberto Manfredini, Artemio Mojón, Ana Moyá, Luis Piñeiro, María T. Ríos, Alfonso Otero, Horia Balan & José R. Fernández. (2013) 2013 Ambulatory Blood Pressure Monitoring Recommendations for the Diagnosis of Adult Hypertension, Assessment of Cardiovascular and other Hypertension-associated Risk, and Attainment of Therapeutic Goals. Chronobiology International 30:3, pages 355-410.
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Diana E. Ayala, Rafael Ucieda & Ramón C. Hermida. (2013) Chronotherapy With Low-Dose Aspirin for Prevention of Complications in Pregnancy. Chronobiology International 30:1-2, pages 260-279.
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Fabio Fabbian, Michael H. Smolensky, Ruana Tiseo, Marco Pala, Roberto Manfredini & Francesco Portaluppi. (2013) Dipper and Non-Dipper Blood Pressure 24-Hour Patterns: Circadian Rhythm–Dependent Physiologic and Pathophysiologic Mechanisms. Chronobiology International 30:1-2, pages 17-30.
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Francesco Portaluppi, Erhard Haus & Michael H. Smolensky. (2013) Ambulatory Blood Pressure Monitoring: Killing the Elephant to Get Its Hair? No More, Please!. Chronobiology International 30:1-2, pages 1-5.
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Diana E. Ayala & Ramón C. Hermida. (2013) Ambulatory Blood Pressure Monitoring for the Early Identification of Hypertension in Pregnancy. Chronobiology International 30:1-2, pages 233-259.
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Ramón C. Hermida, Diana E. Ayala, José R. Fernández, Artemio Mojón, Michael H. Smolensky, Fabio Fabbian & Francesco Portaluppi. (2013) Administration-Time Differences in Effects of Hypertension Medications on Ambulatory Blood Pressure Regulation. Chronobiology International 30:1-2, pages 280-314.
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Artemio Mojón, Diana E. Ayala, Luis Piñeiro, Alfonso Otero, Juan J. Crespo, Ana Moyá, Julia Bóveda, Jesús Pérez de Lis, José R. Fernández & Ramón C. Hermida. (2013) Comparison of Ambulatory Blood Pressure Parameters of Hypertensive Patients With and Without Chronic Kidney Disease. Chronobiology International 30:1-2, pages 145-158.
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Ana Moyá, Juan J. Crespo, Diana E. Ayala, María T. Ríos, Lorenzo Pousa, Pedro A. Callejas, José L. Salgado, Artemio Mojón, José R. Fernández & Ramón C. Hermida. (2013) Effects of Time-of-Day of Hypertension Treatment on Ambulatory Blood Pressure and Clinical Characteristics of Patients With Type 2 Diabetes. Chronobiology International 30:1-2, pages 116-131.
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Ramón C. Hermida, Diana E. Ayala, Artemio Mojón & José R. Fernández. (2013) Ambulatory Blood Pressure Thresholds for Diagnosis of Hypertension in Patients With and Without Type 2 Diabetes Based on Cardiovascular Outcomes. Chronobiology International 30:1-2, pages 132-144.
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Ramón C. Hermida, Diana E. Ayala, José R. Fernández & Artemio Mojón. (2013) Sleep-Time Blood Pressure: Prognostic Value and Relevance as a Therapeutic Target for Cardiovascular Risk Reduction. Chronobiology International 30:1-2, pages 68-86.
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Ramón C. Hermida, Diana E. Ayala, Artemio Mojón & José R. Fernández. (2013) Role of Time-of-Day of Hypertension Treatment on the J-Shaped Relationship Between Blood Pressure and Cardiovascular Risk. Chronobiology International 30:1-2, pages 328-339.
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Ramón C. Hermida, Diana E. Ayala, Artemio Mojón & José R. Fernández. (2013) Cardiovascular Risk of Essential Hypertension: Influence of Class, Number, and Treatment-Time Regimen of Hypertension Medications. Chronobiology International 30:1-2, pages 315-327.
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Diana E. Ayala, Ana Moyá, Juan J. Crespo, Carmen Castiñeira, Manuel Domínguez-Sardiña, Sonia Gomara, Elvira Sineiro, Artemio Mojón, María J. Fontao & Ramón C. Hermida. (2013) Circadian Pattern of Ambulatory Blood Pressure in Hypertensive Patients With and Without Type 2 Diabetes. Chronobiology International 30:1-2, pages 99-115.
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Ramón C. Hermida, Diana E. Ayala, Artemio Mojón, María J. Fontao, Luisa Chayán & José R. Fernández. (2013) Differences Between Men and Women in Ambulatory Blood Pressure Thresholds for Diagnosis of Hypertension Based on Cardiovascular Outcomes. Chronobiology International 30:1-2, pages 221-232.
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Ramón C. Hermida, María T. Ríos, Juan J. Crespo, Ana Moyá, Manuel Domínguez-Sardiña, Alfonso Otero, Juan J. Sánchez, Artemio Mojón, José R. Fernández & Diana E. Ayala. (2013) Treatment-Time Regimen of Hypertension Medications Significantly Affects Ambulatory Blood Pressure and Clinical Characteristics of Patients With Resistant Hypertension. Chronobiology International 30:1-2, pages 192-206.
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Juan J. Crespo, Luis Piñeiro, Alfonso Otero, Carmen Castiñeira, María T. Ríos, Antonio Regueiro, Artemio Mojón, Sonia Lorenzo, Diana E. Ayala & Ramón C. Hermida. (2013) Administration-Time-Dependent Effects of Hypertension Treatment on Ambulatory Blood Pressure in Patients With Chronic Kidney Disease. Chronobiology International 30:1-2, pages 159-175.
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Ramón C. Hermida, Diana E. Ayala, María J. Fontao, Artemio Mojón,José R. Fernández. (2013) Ambulatory Blood Pressure Monitoring: Importance of Sampling Rate and Duration—48 Versus 24 Hours—on the Accurate Assessment of Cardiovascular Risk. Chronobiology International 30:1-2, pages 55-67.
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María T. Ríos, Manuel Domínguez-Sardiña, Diana E. Ayala, Sonia Gomara, Elvira Sineiro, Lorenzo Pousa, Pedro A. Callejas, María J. Fontao, José R. Fernández & Ramón C. Hermida. (2013) Prevalence and Clinical Characteristics of Isolated-Office and True Resistant Hypertension Determined by Ambulatory Blood Pressure Monitoring. Chronobiology International 30:1-2, pages 207-220.
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Ramón C. Hermida, Diana E. Ayala, Juan J. Crespo, Artemio Mojón, Luisa Chayán, María J. Fontao & José R. Fernández. (2013) Influence of Age and Hypertension Treatment-time on Ambulatory Blood Pressure in Hypertensive Patients. Chronobiology International 30:1-2, pages 176-191.
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Ramón C. Hermida, Diana E. Ayala, Artemio Mojón & José R. Fernández. (2013) Blunted Sleep-Time Relative Blood Pressure Decline Increases Cardiovascular Risk Independent of Blood Pressure Level—The “Normotensive Non-dipper” Paradox. Chronobiology International 30:1-2, pages 87-98.
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Ramón C. Hermida, Diana E. Ayala, Michael H. Smolensky, Artemio Mojón, José R. Fernández, Juan J. Crespo, Ana Moyá, María T. Ríos & Francesco Portaluppi. (2013) Chronotherapy improves blood pressure control and reduces vascular risk in CKD. Nature Reviews Nephrology 9:6, pages 358-368.
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