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Annals of Medicine Volume 46, 2014 - Issue 3
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Research Articles

Advice to follow a low-carbohydrate diet has a favourable impact on low-grade inflammation in type 2 diabetes compared with advice to follow a low-fat diet

Lena JonassonDivision of Cardiovascular Medicine, Department of Medical and Health Sciences, Faculty of Health Science, Linköping University, SE-581 85 Linköping, SwedenCorrespondence[email protected]
,
Hans GuldbrandDivision of Cardiovascular Medicine, Department of Medical and Health Sciences, Faculty of Health Science, Linköping University, SE-581 85 Linköping, Sweden
,
Anna K. LundbergDivision of Cardiovascular Medicine, Department of Medical and Health Sciences, Faculty of Health Science, Linköping University, SE-581 85 Linköping, Sweden
&
Fredrik H. NystromDivision of Cardiovascular Medicine, Department of Medical and Health Sciences, Faculty of Health Science, Linköping University, SE-581 85 Linköping, Sweden
Pages 182-187 | Received 11 Dec 2013, Accepted 07 Feb 2014, Published online: 30 Apr 2014

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Crossref
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Stella Iacovides & Rebecca M. Meiring. (2018) The effect of a ketogenic diet versus a high-carbohydrate, low-fat diet on sleep, cognition, thyroid function, and cardiovascular health independent of weight loss: study protocol for a randomized controlled trial. Trials 19:1.
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Crossref
Sara Nordkvist, Emily Sonestedt & Stefan Acosta. (2018) Adherence to diet recommendations and risk of abdominal aortic aneurysm in the Malmö Diet and Cancer Study. Scientific Reports 8:1.
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Crossref
Kristine A Whalen, Marjorie L McCullough, W Dana Flanders, Terryl J Hartman, Suzanne Judd & Roberd M Bostick. (2016) Paleolithic and Mediterranean Diet Pattern Scores Are Inversely Associated with Biomarkers of Inflammation and Oxidative Balance in Adults. The Journal of Nutrition 146:6, pages 1217-1226.
Crossref
Louis Jacob, Lilia Waehlert & Karel Kostev. (2016) Changes in Type 2 Diabetes Mellitus Patients in German Primary Care Prior to (2006) and After (2010, 2014) Launch of New Drugs. Journal of Diabetes Science and Technology 10:2, pages 414-420.
Crossref
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Crossref
Jung Ah Lee, Young Hwa Cha, Sun Hee Kim & Hye Soon Park. (2016) Impact of combined lifestyle factors on metabolic syndrome in Korean men. Journal of Public Health, pages fdv208.
Crossref
Jose Lopez-Miranda & Carmen Marin. 2016. Molecular Nutrition and Diabetes. Molecular Nutrition and Diabetes 301 311 .
Giovanni Annuzzi, Ettore Griffo, Giuseppina Costabile & Lutgarda Bozzetto. 2016. Molecular Nutrition and Diabetes. Molecular Nutrition and Diabetes 221 236 .
Lee Hooper, Asmaa Abdelhamid, Diane Bunn, Tracey Brown, Carolyn D Summerbell & C Murray Skeaff. (2015) Effects of total fat intake on body weight. Cochrane Database of Systematic Reviews 2016:8.
Crossref
Angela A. Stanton. (2018) Input for the Draft Strategic Plan for NIH Nutrition Research: Comment. SSRN Electronic Journal.
Crossref

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