1,827
Views
44
CrossRef citations to date
0
Altmetric
Research Article

Circulating purine compounds, uric acid, and xanthine oxidase/dehydrogenase relationship in essential hypertension and end stage renal disease

, , , , , , , , , , & show all
Pages 613-618 | Received 23 Oct 2013, Accepted 04 Dec 2013, Published online: 06 Feb 2014

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (5)

Xiaoxin Zhou, Longlong Zhang, Xiaoqian Lin, Xi Chen, Hong Liu, Xiaoli Yuan, Qiuxia Zhao, Weiwei Wang, Xun Lei, Pedro A Jose, Chunyan Deng & Jian Yang. (2023) Thrombospondin 2 is a novel biomarker of essential hypertension and associated with nocturnal Na+ excretion and insulin resistance. Clinical and Experimental Hypertension 45:1.
Read now
Gülşen Kaya, Samir Abbas Ali Noma, Duygu Barut Celepci, İmren Bayıl, Tugba Taskin-Tok, Yetkin Gök, Burhan Ateş, Aydın Aktaş, Muhittin Aygün & Burcu Tezcan. (2023) Design, synthesis, spectroscopic characterizations, single crystal X-ray analysis, in vitro xanthine oxidase and acetylcholinesterase inhibitory evaluation as well as in silico evaluation of selenium-based N-heterocyclic carbene compounds. Journal of Biomolecular Structure and Dynamics 41:21, pages 11728-11747.
Read now
Nagihan Karaaslan Ayhan, Merve Goksin Karaaslan Tunc, Samir Abbas Ali Noma, Ali Kurucay & Burhan Ates. (2022) Characterization of the antioxidant activity, total phenolic content, enzyme inhibition, and anticancer properties of Achillea millefolium L. (yarrow). Instrumentation Science & Technology 50:6, pages 654-667.
Read now
Bing Liu, Meiyue Song, Huadong Qin, Bin Zhang, Yao Liu, Yu Sun, Yanfei Ma & Tiefeng Shi. (2020) Phosphoribosyl Pyrophosphate Amidotransferase Promotes the Progression of Thyroid Cancer via Regulating Pyruvate Kinase M2. OncoTargets and Therapy 13, pages 7629-7639.
Read now
Periklis Dousdampanis, Konstantina Trigka, Carlos G. Musso & Costas Fourtounas. (2014) Hyperuricemia and chronic kidney disease: an enigma yet to be solved. Renal Failure 36:9, pages 1351-1359.
Read now

Articles from other publishers (39)

Qin Wang, Haiying Qi, Yiming Wu, Liping Yu, Rihab Bouchareb, Shuyu Li, Emelie Lassén, Gabriella Casalena, Krisztian Stadler, Kerstin Ebefors, Zhengzi Yi, Shaolin Shi, Fadi Salem, Ronald Gordon, Lu Lu, Robert W. Williams, Jeremy Duffield, Weijia Zhang, Yuval Itan, Erwin Böttinger & Ilse Daehn. (2023) Genetic susceptibility to diabetic kidney disease is linked to promoter variants of XOR. Nature Metabolism 5:4, pages 607-625.
Crossref
Abdussamat Güzel, Samir Abbas Ali Noma, Betül Şen, Ali Kazancı, Tugba Taskin-Tok, Turgay Kolaç, Aydın Aktaş, Burhan Ateş, Muhittin Aygün & Yetkin Gök. (2023) Synthesis, characterization and inhibitor properties of benzimidazolium salts bearing 4-(methylsulfonyl)benzyl side arms. Journal of Molecular Structure 1273, pages 134320.
Crossref
Elżbieta Cecerska-Heryć, Rafał Heryć, Grażyna Dutkiewicz, Anna Michalczyk, Bartłomiej Grygorcewicz, Natalia Serwin, Sylwia Napiontek-Balińska & Barbara Dołęgowska. (2022) Xanthine oxidoreductase activity in platelet-poor and rich plasma as a oxidative stress indicator in patients required renal replacement therapy. BMC Nephrology 23:1.
Crossref
Yaxin Yang, Qian Chen, Shiyang Ruan, Junli Ao & Shang-Gao Liao. (2022) Insights into the Inhibitory Mechanism of Viniferifuran on Xanthine Oxidase by Multiple Spectroscopic Techniques and Molecular Docking. Molecules 27:22, pages 7730.
Crossref
Fu-Chun Huo, Min Xie, Zhi-Man Zhu, Jun-Nian Zheng & Dong-Sheng Pei. (2022) SHMT2 promotes the tumorigenesis of renal cell carcinoma by regulating the m6A modification of PPAT. Genomics 114:4, pages 110424.
Crossref
Ara Aboolian, Sofia Urner, Michael Roden, Jay Chandra Jha & Karin Jandeleit-Dahm. 2022. From Obesity to Diabetes. From Obesity to Diabetes 269 307 .
Letizia Polito, Massimo Bortolotti, Maria Giulia Battelli & Andrea Bolognesi. (2021) Xanthine oxidoreductase: A leading actor in cardiovascular disease drama. Redox Biology 48, pages 102195.
Crossref
Ülkü Yılmaz, Samir Abbas Ali Noma, Tuğba Taşkın Tok, Betül Şen, Yetkin Gök, Aydın Aktaş, Burhan Ateş & Muhittin Aygün. (2021) A study about excellent xanthine oxidase inhibitory effects of new pyridine salts. Monatshefte für Chemie - Chemical Monthly 152:10, pages 1251-1260.
Crossref
Weiqing Ma, Lingjuan Zhou, Yu Li, Daiyang Xia, Jianying Chen, Junpeng Chen, Xianzhi Jiang, Jiangfan Qin, Yujie Zhao, Xiufen Zhang, Heng Wang, Yang Fu, Shanshan Zhu, Huiquan Jiang, Hui Ye, Yongwen Zhu, Zhenping Lin, Wence Wang & Lin Yang. (2021) Persistent Purine Metabolic Abnormality Induces the Aggravation of Visceral Inflammation and Intestinal Microbiota Dysbiosis in Magang Goose. Frontiers in Veterinary Science 8.
Crossref
Xinying Wang, Ming Gao, Zihan Wang, Weiqi Cui, Jingxian Zhang, Weijie Zhang, Yu Xia, Bo Wei, Youcai Tang & Xia Xu. (2021) Hepatoprotective effects of oridonin against bisphenol A induced liver injury in rats via inhibiting the activity of xanthione oxidase. Science of The Total Environment 770, pages 145301.
Crossref
Federica Piani, Arrigo F. G. Cicero & Claudio Borghi. (2021) Uric Acid and Hypertension: Prognostic Role and Guide for Treatment. Journal of Clinical Medicine 10:3, pages 448.
Crossref
Emelie Lassén & Ilse S. Daehn. (2020) Molecular Mechanisms in Early Diabetic Kidney Disease: Glomerular Endothelial Cell Dysfunction. International Journal of Molecular Sciences 21:24, pages 9456.
Crossref
Wei Yu & Ji-Dong Cheng. (2020) Uric Acid and Cardiovascular Disease: An Update From Molecular Mechanism to Clinical Perspective. Frontiers in Pharmacology 11.
Crossref
Seiji Itano, Hiroyuki Kadoya, Minoru Satoh, Takashi Nakamura, Takayo Murase, Tamaki Sasaki, Yashpal S. Kanwar & Naoki Kashihara. (2020) Non-purine selective xanthine oxidase inhibitor ameliorates glomerular endothelial injury in Ins Akita diabetic mice . American Journal of Physiology-Renal Physiology 319:5, pages F765-F772.
Crossref
Rongrong Ou, Lianzhu Lin, Mouming Zhao & Zhiqing Xie. (2020) Action mechanisms and interaction of two key xanthine oxidase inhibitors in galangal: Combination of in vitro and in silico molecular docking studies. International Journal of Biological Macromolecules 162, pages 1526-1535.
Crossref
Andrej Veljković, Jovan Hadži- Đokić, Dušan Sokolović, Rade Čukuranović, Jovana Čukuranović-Kokoris, Dragoslav Bašić, Branka Đorđević, Marko Stojanović, Andrija Šmelcerović & Gordana Kocić. (2020) Local and Systemic Oxidative Stress in Balkan Endemic Nephropathy Is Not Associated with Xanthine Oxidase Activity. Oxidative Medicine and Cellular Longevity 2020, pages 1-8.
Crossref
Xuechen Li, Zhenxin Yan, Mattias Carlström, Jinying Tian, Xiaolin Zhang, Wenxuan Zhang, Song Wu & Fei Ye. (2020) Mangiferin Ameliorates Hyperuricemic Nephropathy Which Is Associated With Downregulation of AQP2 and Increased Urinary Uric Acid Excretion. Frontiers in Pharmacology 11.
Crossref
Prathapan Ayyappan & Suresh V. Nampoothiri. 2020. Bioactive Natural Products. Bioactive Natural Products 391 416 .
Kahori Washio, Yoshiki Kusunoki, Taku Tsunoda, Keiko Osugi, Mana Ohigashi, Takayo Murase, Takashi Nakamura, Toshihiro Matsuo, Kosuke Konishi, Tomoyuki Katsuno, Mitsuyoshi Namba & Hidenori Koyama. (2019) Xanthine oxidoreductase activity correlates with vascular endothelial dysfunction in patients with type 1 diabetes. Acta Diabetologica 57:1, pages 31-39.
Crossref
Aydın Aktaş, Samir Abbas Ali Noma, Duygu Barut Celepci, Fatoş Erdemir, Yetkin Gök & Burhan Ateş. (2019) New 2-hydroxyethyl substituted N-Heterocyclic carbene precursors: Synthesis, characterization, crystal structure and inhibitory properties against carbonic anhydrase and xanthine oxidase. Journal of Molecular Structure 1184, pages 487-494.
Crossref
Muhammed Khairujjaman Mazumder, Rajib Paul, Pallab Bhattacharya & Anupom Borah. (2019) Neurological sequel of chronic kidney disease: From diminished Acetylcholinesterase activity to mitochondrial dysfunctions, oxidative stress and inflammation in mice brain. Scientific Reports 9:1.
Crossref
Aleksandra Klisic, Gordana Kocic, Nebojsa Kavaric, Milovan Jovanovic, Verica Stanisic & Ana Ninic. (2017) Xanthine oxidase and uric acid as independent predictors of albuminuria in patients with diabetes mellitus type 2. Clinical and Experimental Medicine 18:2, pages 283-290.
Crossref
Jun Cao, Yijun Mi, Cuilin Shi, Yicong Bian, Chenrong Huang, Zhijian Ye, Linsheng Liu & Liyan Miao. (2018) First-line anti-tuberculosis drugs induce hepatotoxicity: A novel mechanism based on a urinary metabolomics platform. Biochemical and Biophysical Research Communications 497:2, pages 485-491.
Crossref
Muhammed Khairujjaman Mazumder, Banashree Chetia Phukan, Aradhana Bhattacharjee & Anupom Borah. (2018) Disturbed purine nucleotide metabolism in chronic kidney disease is a risk factor for cognitive impairment. Medical Hypotheses 111, pages 36-39.
Crossref
Ayumi Nakatani, Shinya Nakatani, Eiji Ishimura, Takayo Murase, Takashi Nakamura, Mari Sakura, Yu Tateishi, Akihiro Tsuda, Masafumi Kurajoh, Katsuhito Mori, Masanori Emoto & Masaaki Inaba. (2017) Xanthine oxidoreductase activity is associated with serum uric acid and glycemic control in hemodialysis patients. Scientific Reports 7:1.
Crossref
Zhaodi Xie, Xiaoting Luo, Zhuan Zou, Xiao Zhang, Feifei Huang, Ruishan Li, Shijie Liao & Yun Liu. (2017) Synthesis and evaluation of hydroxychalcones as multifunctional non-purine xanthine oxidase inhibitors for the treatment of hyperuricemia. Bioorganic & Medicinal Chemistry Letters 27:15, pages 3602-3606.
Crossref
Kahori (Watanabe) Washio, Yoshiki Kusunoki, Takayo Murase, Takashi Nakamura, Keiko Osugi, Mana Ohigashi, Tadahiko Sukenaga, Fumihiro Ochi, Toshihiro Matsuo, Tomoyuki Katsuno, Yuji Moriwaki, Tetsuya Yamamoto, Mitsuyoshi Namba & Hidenori Koyama. (2017) Xanthine oxidoreductase activity is correlated with insulin resistance and subclinical inflammation in young humans. Metabolism 70, pages 51-56.
Crossref
Manroopraj Kaur, Amandeep Kaur, Suhani Mankotia, Harbinder Singh, Arshdeep Singh, Jatinder Vir Singh, Manish Kumar Gupta, Sahil Sharma, Kunal Nepali & Preet Mohinder Singh Bedi. (2017) Synthesis, screening and docking of fused pyrano[3,2- d ]pyrimidine derivatives as xanthine oxidase inhibitor. European Journal of Medicinal Chemistry 131, pages 14-28.
Crossref
Takayo Murase, Mai Nampei, Mitsuru Oka, Atsushi Miyachi & Takashi Nakamura. (2016) A highly sensitive assay of human plasma xanthine oxidoreductase activity using stable isotope-labeled xanthine and LC/TQMS. Journal of Chromatography B 1039, pages 51-58.
Crossref
Jin-Jin Lu, Bing-Jie Jia, Lin Yang, Wen Zhang, Xin Dong, Ping Li & Jun Chen. (2016) Ultra-high performance liquid chromatography with ultraviolet and tandem mass spectrometry for simultaneous determination of metabolites in purine pathway of rat plasma. Journal of Chromatography B 1036-1037, pages 84-92.
Crossref
Hong-Gang Li, Pi-Yong Hou, Xi Zhang, Yi He, Jun Zhang, Shu-Qing Wang, Samantha Anderson, Yan-Wen Zhang & Xiao-Hui Wu. (2016) Hypouricemic effect of allopurinol are improved by Pallidifloside D based on the uric acid metabolism enzymes PRPS, HGPRT and PRPPAT. Fitoterapia 113, pages 1-5.
Crossref
Takashi Shirakura, Johji Nomura, Chieko Matsui, Tsunefumi Kobayashi, Mizuho Tamura & Hiroaki Masuzaki. (2016) Febuxostat, a novel xanthine oxidoreductase inhibitor, improves hypertension and endothelial dysfunction in spontaneously hypertensive rats. Naunyn-Schmiedeberg's Archives of Pharmacology 389:8, pages 831-838.
Crossref
Takayo Murase, Mitsuru Oka, Mai Nampei, Atsushi Miyachi & Takashi Nakamura. (2016) A highly sensitive assay for xanthine oxidoreductase activity using a combination of [ 13 C 2 , 15 N 2 ]xanthine and liquid chromatography/triple quadrupole mass spectrometry . Journal of Labelled Compounds and Radiopharmaceuticals 59:5, pages 214-220.
Crossref
Zhuohang Li, Yiyu Sheng, Cheng Liu, Kuiqing Li, Xin Huang, Jian Huang & Kewei Xu. (2016) Nox4 has a crucial role in uric acid-induced oxidative stress and apoptosis in renal tubular cells. Molecular Medicine Reports 13:5, pages 4343-4348.
Crossref
Takayo Murase, Mai Nampei, Mitsuru Oka, Naoki Ashizawa, Koji Matsumoto, Atsushi Miyachi & Takashi Nakamura. (2016) Xanthine oxidoreductase activity assay in tissues using stable isotope-labeled substrate and liquid chromatography high-resolution mass spectrometry. Journal of Chromatography B 1008, pages 189-197.
Crossref
BAOGANG WU, YING HAO, JIN SHI, NING GENG, TIEJUN LI, YANLI CHEN, ZHAOQING SUN, LIQIANG ZHENG, HONG LI, NAIJING LI, XINGANG ZHANG & YINGXIAN SUN. (2015) Association between xanthine dehydrogenase tag single nucleotide polymorphisms and essential hypertension. Molecular Medicine Reports 12:4, pages 5685-5690.
Crossref
Suyun Lin, Guowen Zhang, Yijing Liao, Junhui Pan & Deming Gong. (2015) Dietary Flavonoids as Xanthine Oxidase Inhibitors: Structure–Affinity and Structure–Activity Relationships. Journal of Agricultural and Food Chemistry 63:35, pages 7784-7794.
Crossref
Elżbieta Cecerska-Heryć, Anna Jesionowska, Szupiluk Klaudyna, Siewierska Katarzyna, Mączka Dominika, Pawlak Dominika, Urbańska Marta & Barbara Dołęgowska. (2015) Xanthine Oxidoreductase Reference Values in Platelet-Poor Plasma and Platelets in Healthy Volunteers. Oxidative Medicine and Cellular Longevity 2015, pages 1-6.
Crossref
Emine Rabia Koc, Emre Cemal Gökce, Mehmet Akif Sönmez, Mehmet Namuslu, Aysun Gökce & A. Said Bodur. (2015) Borax Partially Prevents Neurologic Disability and Oxidative Stress in Experimental Spinal Cord Ischemia/Reperfusion Injury. Journal of Stroke and Cerebrovascular Diseases 24:1, pages 83-90.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.