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Autoimmunity Volume 44, 2011 - Issue 8
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Research Article

AID dysregulation in lupus-prone MRL/Faslpr/lpr mice increases class switch DNA recombination and promotes interchromosomal c-Myc/IgH loci translocations: Modulation by HoxC4

Clayton A. WhiteSchool of Medicine and School of Biological Sciences, Institute for Immunology, University of California, 3028 Hewitt Hall, Irvine, CA 92697-4120, USA
,
J. Seth HawkinsSchool of Medicine and School of Biological Sciences, Institute for Immunology, University of California, 3028 Hewitt Hall, Irvine, CA 92697-4120, USA
,
Egest J. PoneSchool of Medicine and School of Biological Sciences, Institute for Immunology, University of California, 3028 Hewitt Hall, Irvine, CA 92697-4120, USA
,
Elliot S. YuSchool of Medicine and School of Biological Sciences, Institute for Immunology, University of California, 3028 Hewitt Hall, Irvine, CA 92697-4120, USA
,
Ahmed Al-QahtaniSchool of Medicine and School of Biological Sciences, Institute for Immunology, University of California, 3028 Hewitt Hall, Irvine, CA 92697-4120, USA
,
Thach MaiSchool of Medicine and School of Biological Sciences, Institute for Immunology, University of California, 3028 Hewitt Hall, Irvine, CA 92697-4120, USA
,
Hong ZanSchool of Medicine and School of Biological Sciences, Institute for Immunology, University of California, 3028 Hewitt Hall, Irvine, CA 92697-4120, USA
&
Paolo CasaliSchool of Medicine and School of Biological Sciences, Institute for Immunology, University of California, 3028 Hewitt Hall, Irvine, CA 92697-4120, USACorrespondence[email protected]
 show all
Pages 585-598 | Received 18 Feb 2011, Accepted 29 Mar 2011, Published online: 18 May 2011

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Ming Yang, Ping Yi, Jiao Jiang, Ming Zhao, Haijing Wu & Qianjin Lu. (2023) Dysregulated translational factors and epigenetic regulations orchestrate in B cells contributing to autoimmune diseases. International Reviews of Immunology 42:1, pages 1-25.
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Stelios Vlachiotis & Hassan Abolhassani. (2022) Transcriptional regulation of B cell class-switch recombination: the role in development of noninfectious complications. Expert Review of Clinical Immunology 18:11, pages 1145-1154.
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Meenal Choudhary, Anubhav Tamrakar, Amit Kumar Singh, Monika Jain, Ankit Jaiswal & Prashant Kodgire. (2018) AID Biology: A pathological and clinical perspective. International Reviews of Immunology 37:1, pages 37-56.
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Egest J. Pone, Zheng Lou, Tonika Lam, Milton L. Greenberg, Rui Wang, Zhenming Xu & Paolo Casali. (2015) B cell TLR1/2, TLR4, TLR7 and TLR9 interact in induction of class switch DNA recombination: Modulation by BCR and CD40, and relevance to T-independent antibody responses. Autoimmunity 48:1, pages 1-12.
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Hong Zan, Connie Tat & Paolo Casali. (2014) MicroRNAs in lupus. Autoimmunity 47:4, pages 272-285.
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Hong Zan & Paolo Casali. (2013) Regulation of Aicda expression and AID activity. Autoimmunity 46:2, pages 83-101.
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Elisabetta Incorvaia, Lara Sicouri, Svend K. Petersen-Mahrt & Kerstin-Maike Schmitz. (2013) Hormones and AID: Balancing immunity and autoimmunity. Autoimmunity 46:2, pages 128-137.
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Hannah Peckham, Kate Webb, Elizabeth C. Rosser, Gary Butler & Coziana Ciurtin. (2022) Gender-Diverse Inclusion in Immunological Research: Benefits to Science and Health. Frontiers in Medicine 9.
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Paolo Casali, Tian Shen, Yijiang Xu, Zhifang Qiu, Daniel P. Chupp, John Im, Zhenming Xu & Hong Zan. (2020) Estrogen Reverses HDAC Inhibitor-Mediated Repression of Aicda and Class-Switching in Antibody and Autoantibody Responses by Downregulation of miR-26a. Frontiers in Immunology 11.
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Helia N. Sanchez, Justin B. Moroney, Huoqun Gan, Tian Shen, John L. Im, Tianbao Li, Julia R. Taylor, Hong Zan & Paolo Casali. (2020) B cell-intrinsic epigenetic modulation of antibody responses by dietary fiber-derived short-chain fatty acids. Nature Communications 11:1.
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Scott Feldman, Ikbel Achour, Robert Wuerffel, Satyendra Kumar, Tatiana Gerasimova, Ranjan Sen & Amy L. Kenter. (2015) Constraints Contributed by Chromatin Looping Limit Recombination Targeting during Ig Class Switch Recombination. The Journal of Immunology 194:5, pages 2380-2389.
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Clayton A. White, Egest J. Pone, Tonika Lam, Connie Tat, Ken L. Hayama, Guideng Li, Hong Zan & Paolo Casali. (2014) Histone Deacetylase Inhibitors Upregulate B Cell microRNAs That Silence AID and Blimp-1 Expression for Epigenetic Modulation of Antibody and Autoantibody Responses. The Journal of Immunology 193:12, pages 5933-5950.
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Alexandre Orthwein & Javier M. Di Noia. (2012) Activation induced deaminase: How much and where?. Seminars in Immunology 24:4, pages 246-254.
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Zhenming Xu, Hong Zan, Egest J. Pone, Thach Mai & Paolo Casali. (2012) Immunoglobulin class-switch DNA recombination: induction, targeting and beyond. Nature Reviews Immunology 12:7, pages 517-531.
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Guideng Li, Egest J. Pone, Daniel C. Tran, Pina J. Patel, Lisa Dao, Zhenming Xu & Paolo Casali. (2012) Iron Inhibits Activation-induced Cytidine Deaminase Enzymatic Activity and Modulates Immunoglobulin Class Switch DNA Recombination. Journal of Biological Chemistry 287:25, pages 21520-21529.
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