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Inhalation Toxicology
International Forum for Respiratory Research
Volume 25, 2013 - Issue 5
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Research Article

Estimate of safe human exposure levels for lunar dust based on comparative benchmark dose modeling

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Pages 243-256 | Received 19 Dec 2012, Accepted 15 Feb 2013, Published online: 24 Apr 2013

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Chiu-wing Lam, Vincent Castranova, Patti C. Zeidler-Erdely, Roger Renne, Robert Hunter, Richard McCluskey, Robert R. Scully, William T. Wallace, Ye Zhang, Valerie E. Ryder, Bonnie Cooper, David McKay, Roger O. McClellan, Kevin E. Driscoll, Donald E. Gardner, Mark Barger, Terence Meighan & John T. James. (2022) Comparative pulmonary toxicities of lunar dusts and terrestrial dusts (TiO2 & SiO2) in rats and an assessment of the impact of particle-generated oxidants on the dusts’ toxicities. Inhalation Toxicology 34:3-4, pages 51-67.
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Robert R. Scully, Chiu-Wing Lam & John T. James. (2013) Estimating safe human exposure levels for lunar dust using benchmark dose modeling of data from inhalation studies in rats. Inhalation Toxicology 25:14, pages 785-793.
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Chiu-wing Lam, Robert R. Scully, Ye Zhang, Roger A. Renne, Robert L. Hunter, Richard A. McCluskey, Bean T. Chen, Vincent Castranova, Kevin E. Driscoll, Donald E. Gardner, Roger O. McClellan, Bonnie L. Cooper, David S. McKay, Linda Marshall & John T. James. (2013) Toxicity of lunar dust assessed in inhalation-exposed rats. Inhalation Toxicology 25:12, pages 661-678.
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Articles from other publishers (17)

Silvana Miranda, Shannon Marchal, Lina Cumps, Jenne Dierckx, Marcus Krüger, Daniela Grimm, Sarah Baatout, Kevin Tabury & Bjorn Baselet. (2023) A Dusty Road for Astronauts. Biomedicines 11:7, pages 1921.
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Jon Rask. 2023. Encyclopedia of Lunar Science. Encyclopedia of Lunar Science 566 568 .
Michael Pohlen, Danielle Carroll, G. Kim Prisk & Aenor J. Sawyer. (2022) Overview of lunar dust toxicity risk. npj Microgravity 8:1.
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Vladimir A. Barinov & Igor B. Ushakov. (2022) Toxicology of lunar dust in the aspect of possible occupational pathology of astronauts participating in an expedition to the Moon (review). Russian Journal of Occupational Health and Industrial Ecology 62:2, pages 72-90.
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Robert Mulcahy, Grace Douglas, Torin McCoy & Erik Antonsen. 2020. Handbook of Lunar Base Design and Development. Handbook of Lunar Base Design and Development 1 28 .
Donald A. Hendrix, Joel A. Hurowitz, Timothy D. Glotch & Martin A. A. Schoonen. (2021) Olivine Dissolution in Simulated Lung and Gastric Fluid as an Analog to the Behavior of Lunar Particulate Matter Inside the Human Respiratory and Gastrointestinal Systems. GeoHealth 5:11.
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Martin Braddock. 2021. The Human Factor in the Settlement of the Moon. The Human Factor in the Settlement of the Moon 141 157 .
Yan Sun, Lu Zhang, Jinguo Liu, Xiaoping Zhang, Yan Su, Quanling Yin & Shuangxi He. (2019) Effects of lunar dust simulant on cardiac function and fibrosis in rats. Toxicology Research 8:4, pages 499-508.
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Yan Sun, Jinguo Liu, Xiaoping Zhang, Xiongyao Li, Baichu Zhou & Zengjing Lv. (2019) Mechanisms involved in inflammatory pulmonary fibrosis induced by lunar dust simulant in rats. Environmental Toxicology 34:2, pages 131-140.
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Donald A. Hendrix, Sara T. Port, Joel A. Hurowitz & Martin A. Schoonen. (2019) Measurement of OH* Generation by Pulverized Minerals Using Electron Spin Resonance Spectroscopy and Implications for the Reactivity of Planetary Regolith. GeoHealth 3:1, pages 28-42.
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John T. James & Valerie E. Ryder. 2019. Principles of Clinical Medicine for Space Flight. Principles of Clinical Medicine for Space Flight 153 174 .
Jon Rask. 2018. Encyclopedia of Lunar Science. Encyclopedia of Lunar Science 1 3 .
Jasmeet Kaur, Douglas Rickman & Martin A. Schoonen. (2016) Reactive Oxygen Species (ROS) generation by lunar simulants. Acta Astronautica 122, pages 196-208.
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John T. James. 2016. Space Physiology and Medicine. Space Physiology and Medicine 137 153 .
Arnauld E. Nicogossian. 2016. Space Physiology and Medicine. Space Physiology and Medicine 59 94 .
James T.F. WiseHong XieJohn Pierce WiseJr.Jr., Michael MasonAntony JeevarajanWilliam Wallace & John Pierce WiseSr.Sr.. (2015) Comparative Toxicity of Lunar, Martian Dust Simulants, and Urban Dust in Human Skin Fibroblast Cells. Gravitational and Space Research 3:1, pages 51-58.
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D.S. McKay, B.L. Cooper, L.A. Taylor, J.T. James, K. Thomas-Keprta, C.M. Pieters, S.J. Wentworth, W.T. Wallace & T.S. Lee. (2015) Physicochemical properties of respirable-size lunar dust. Acta Astronautica 107, pages 163-176.
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