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International Journal of Radiation Biology Volume 89, 2013 - Issue 4
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DNA DAMAGE RESPONSE IN CD133+ CELLS FROM UMBILICAL CORD BLOOD

DNA damage response in CD133 + stem/progenitor cells from umbilical cord blood: Low level of endogenous foci and high recruitment of 53BP1

Stanislav A. VasilyevLaboratory of Molecular Genetics, Cancer Research Institute, Bratislava, Slovak Republic;Laboratory of Cytogenetics, Institute of Medical Genetics, Tomsk, Russia
,
Miroslav KubesLaboratory of Cell Biology, Eurocord-Slovakia, Bratislava, Slovak Republic
,
Eva MarkovaLaboratory of Molecular Genetics, Cancer Research Institute, Bratislava, Slovak Republic
&
Igor BelyaevLaboratory of Molecular Genetics, Cancer Research Institute, Bratislava, Slovak Republic;Laboratory of Radiobiology, General Physics Institute, Russian Academy of Science, Moscow, RussiaCorrespondence[email protected]
Pages 301-309 | Received 11 Jan 2012, Accepted 23 Nov 2012, Published online: 08 Jan 2013

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Lukáš Jakl, Pavel Lobachevsky, Lenka Vokálová, Matúš Durdík, Eva Marková & Igor Belyaev. (2016) Validation of JCountPro software for efficient assessment of ionizing radiation-induced foci in human lymphocytes. International Journal of Radiation Biology 92:12, pages 766-773.
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Eva Marková, Alexandra Somsedíková, Stanislav Vasilyev, Margita Pobijaková, Alica Lacková, Pavol Lukačko & Igor Belyaev. (2015) DNA repair foci and late apoptosis/necrosis in peripheral blood lymphocytes of breast cancer patients undergoing radiotherapy. International Journal of Radiation Biology 91:12, pages 934-945.
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Stamatia Pouliliou & Michael I. Koukourakis. (2014) Gamma histone 2AX (γ-H2AX)as a predictive tool in radiation oncology. Biomarkers 19:3, pages 167-180.
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Svetlana Sorokina, Eva Markova, Jan Gursky, Jozef Dobrovodsky & Igor Belyaev. (2013) Relative biological efficiency of protons at low and therapeutic doses in induction of 53BP1/γH2AX foci in lymphocytes from umbilical cord blood. International Journal of Radiation Biology 89:9, pages 716-723.
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Articles from other publishers (20)

Lucián Zastko, Leonardo Makinistian, Andrea Tvarožná & Igor Belyaev. (2022) Intermittent ELF-MF Induce an Amplitude-Window Effect on Umbilical Cord Blood Lymphocytes. International Journal of Molecular Sciences 23:22, pages 14391.
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Zastko Lucian, Bereta Martin, Timko Jaroslav & Belyaev Igor. (2022) Classifier Spot Count Optimization of Automated Fluorescent Slide Scanning System. Acta Medica Martiniana 22:1, pages 24-33.
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Matus Durdik, Pavol Kosik, Lukas Jakl, Maria Kozackova, Eva Markova, Katarina Vigasova, Katarina Beresova, Jana Jakubikova, Eva Horvathova, Lucian Zastko, Marta Fekete, Ingrid Zavacka, Margita Pobijakova & Igor Belyaev. (2021) Imaging flow cytometry and fluorescence microscopy in assessing radiation response in lymphocytes from umbilical cord blood and cancer patients. Cytometry Part A 99:12, pages 1198-1208.
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Monique Engelbrecht, Roya Ndimba, Maryna de Kock, Xanthene Miles, Shankari Nair, Randall Fisher, Peter du Plessis, Julie Bolcaen, Matthys Hendrik Botha, Elbie Zwanepoel, Simon Sioen, Ans Baeyens, Jaime Nieto-Camero, Evan de Kock & Charlot Vandevoorde. (2021) DNA damage response of haematopoietic stem and progenitor cells to high-LET neutron irradiation. Scientific Reports 11:1.
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Lucián Zastko, Petra Petrovičová, Anna Račková, Lukáš Jakl, Viera Jakušová, Eva Marková & Igor Belyaev. (2021) DNA damage response and apoptosis induced by hyperthermia in human umbilical cord blood lymphocytes. Toxicology in Vitro 73, pages 105127.
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Lucián Zastko, Anna Račková, Petra Petrovičová, Matúš Durdík, Jakub Míšek, Eva Marková & Igor Belyaev. (2021) Evaluation of Calyculin A Effect on γH2AX/53BP1 Focus Formation and Apoptosis in Human Umbilical Cord Blood Lymphocytes. International Journal of Molecular Sciences 22:11, pages 5470.
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Pavol Kosik, Matus Durdik, Milan Skorvaga, Daniela Klimova, Dominika Kochanova, Zlatica Cerna, Miroslav Kubes, Marek Holop & Igor Belyaev. (2021) Induction of AML Preleukemic Fusion Genes in HSPCs and DNA Damage Response in Preleukemic Fusion Gene Positive Samples. Antioxidants 10:3, pages 481.
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Sachin Gulati, Pavol Kosik, Matus Durdik, Milan Skorvaga, Lukas Jakl, Eva Markova & Igor Belyaev. (2020) Effects of different mobile phone UMTS signals on DNA, apoptosis and oxidative stress in human lymphocytes. Environmental Pollution 267, pages 115632.
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Lucián Zastko, Leonardo Makinistian, Andrea Moravčíková, Ján Jakuš & Igor Belyaev. (2020) Effect of Intermittent ELF MF on Umbilical Cord Blood Lymphocytes. Bioelectromagnetics 41:8, pages 649-655.
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Pavol Kosik, Matus Durdik, Lukas Jakl, Milan Skorvaga, Eva Markova, Gabriela Vesela, Lenka Vokalova, Lucia Kolariková, Eva Horvathova, Katarina Kozics & Igor Belyaev. (2020) DNA damage response and preleukemic fusion genes induced by ionizing radiation in umbilical cord blood hematopoietic stem cells. Scientific Reports 10:1.
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Lukáš Jakl, Eva Marková, Lucia Koláriková & Igor Belyaev. (2020) Biodosimetry of Low Dose Ionizing Radiation Using DNA Repair Foci in Human Lymphocytes. Genes 11:1, pages 58.
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Matus Durdik, Pavol Kosik, Eva Markova, Alexandra Somsedikova, Beata Gajdosechova, Ekaterina Nikitina, Eva Horvathova, Katarina Kozics, Devra Davis & Igor Belyaev. (2019) Microwaves from mobile phone induce reactive oxygen species but not DNA damage, preleukemic fusion genes and apoptosis in hematopoietic stem/progenitor cells. Scientific Reports 9:1.
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Shahar Biechonski, Leonid Olender, Adi Zipin-Roitman, Muhammad Yassin, Nasma Aqaqe, Victoria Marcu-Malina, Melanie Rall-Scharpf, Magan Trottier, M. Stephen Meyn, Lisa Wiesmüller, Katia Beider, Yael Raz, Dan Grisaru, Arnon Nagler & Michael Milyavsky. (2018) Attenuated DNA damage responses and increased apoptosis characterize human hematopoietic stem cells exposed to irradiation. Scientific Reports 8:1.
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Fang Yuan, Lu Liu, Yonghong Lei & Yi Hu. (2018) MiRNA-142-3p increases radiosensitivity in human umbilical cord blood mononuclear cells by inhibiting the expression of CD133. Scientific Reports 8:1.
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Henning Hintzsche, Gracia Montag & Helga Stopper. (2018) Induction of micronuclei by four cytostatic compounds in human hematopoietic stem cells and human lymphoblastoid TK6 cells. Scientific Reports 8:1.
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Matus Durdik, Pavol Kosik, Jana Kruzliakova, Lukas Jakl, Eva Markova & Igor Belyaev. (2017) Hematopoietic stem/progenitor cells are less prone to undergo apoptosis than lymphocytes despite similar DNA damage response. Oncotarget 8:30, pages 48846-48853.
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Defang Ding, Yaping Zhang, Jing Wang, Xufei Wang, Dunhuang Fan, Linfeng He, Xuxia Zhang, Yun Gao, Qiang Li & Honghong Chen. (2016) γ-H2AX/53BP1/pKAP-1 foci and their linear tracks induced by in vitro exposure to radon and its progeny in human peripheral blood lymphocytes. Scientific Reports 6:1.
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C. Vandevoorde, A. Vral, B. Vandekerckhove, J. Philippé & H. Thierens. (2016) Radiation Sensitivity of Human CD34 + Cells Versus Peripheral Blood T Lymphocytes of Newborns and Adults: DNA Repair and Mutagenic Effects . Radiation Research 185:6, pages 580-590.
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Matus Durdik, Pavol Kosik, Jan Gursky, Lenka Vokalova, Eva Markova & Igor Belyaev. (2015) Imaging flow cytometry as a sensitive tool to detect low-dose-induced DNA damage by analyzing 53BP1 and γH2AX foci in human lymphocytes. Cytometry Part A 87:12, pages 1070-1078.
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Yoshishige Urata, Shinji Goto, Lan Luo, Hanako Doi, Yuriko Kitajima, Shinya Masuda, Yusuke Ono & Tao-Sheng Li. (2014) Enhanced Nox1 expression and oxidative stress resistance in c-kit-positive hematopoietic stem/progenitor cells. Biochemical and Biophysical Research Communications 454:3, pages 376-380.
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