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In vitro and animal studies

Reduction in cholesterol absorption in Caco-2 cells through the down-regulation of Niemann-Pick C1-like 1 by the putative probiotic strains Lactobacillus rhamnosus BFE5264 and Lactobacillus plantarum NR74 from fermented foods

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Pages 44-52 | Published online: 20 Jul 2012

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Wan Heo, Eui Seop Lee, Hyung Taek Cho, Jun Ho Kim, Jin Hyup Lee, Seok Min Yoon, Hoon Tae Kwon, Siyoung Yang & Young-Jun Kim. (2018) Lactobacillus plantarum LRCC 5273 isolated from Kimchi ameliorates diet-induced hypercholesterolemia in C57BL/6 mice. Bioscience, Biotechnology, and Biochemistry 82:11, pages 1964-1972.
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Bo Zhang, Xinxin Wang, Ran Xia & Chunsheng Li. (2020) Gut microbiota in coronary artery disease: a friend or foe?. Bioscience Reports 40:5.
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Victoria L. O'Morain & Dipak P. Ramji. (2019) The Potential of Probiotics in the Prevention and Treatment of Atherosclerosis. Molecular Nutrition & Food Research 64:4, pages 1900797.
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Bao Le & Seung-Hwan Yang. (2018) Identification of a Novel Potential Probiotic Lactobacillus plantarum FB003 Isolated from Salted-Fermented Shrimp and its Effect on Cholesterol Absorption by Regulation of NPC1L1 and PPARα. Probiotics and Antimicrobial Proteins 11:3, pages 785-793.
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Bao Le & Seung-Hwan Yang. (2018) Effect of potential probiotic Leuconostoc mesenteroides FB111 in prevention of cholesterol absorption by modulating NPC1L1/PPARα/SREBP-2 pathways in epithelial Caco-2 cells. International Microbiology 22:2, pages 279-287.
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Šárka Horáčková, Milada Plocková & Kateřina Demnerová. (2018) Importance of microbial defence systems to bile salts and mechanisms of serum cholesterol reduction. Biotechnology Advances 36:3, pages 682-690.
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Felicia D. Duke Boynton, Aaron C. Ericsson, Mayu Uchihashi, Misha L. Dunbar & J. Erby Wilkinson. (2017) Doxycycline induces dysbiosis in female C57BL/6NCrl mice. BMC Research Notes 10:1.
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Sang-Haeng Choi, Yosep Ji, Soyoung Park, Julius Mathara, Wilhelm Holzapfel & Jihee Kang. (2017) Complete Genome Sequence of Lactobacillus rhamnosus BFE5264, Isolated from Maasai Traditional Fermented Milk. Genome Announcements 5:27.
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D. R. Michael, T. S. Davies, J. W. E. Moss, D. Lama Calvente, D. P. Ramji, J. R. Marchesi, A. Pechlivanis, S. F. Plummer & T. R. Hughes. (2017) The anti-cholesterolaemic effect of a consortium of probiotics: An acute study in C57BL/6J mice. Scientific Reports 7:1.
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Fei Tieng Lim, Siong Meng Lim & Kalavathy Ramasamy. (2017) Cholesterol lowering by Pediococcus acidilactici LAB4 and Lactobacillus plantarum LAB12 in adult zebrafish is associated with improved memory and involves an interplay between npc1l1 and abca1. Food & Function 8:8, pages 2817-2828.
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D.R. Michael, J.W.E. Moss, D. Lama Calvente, I. Garaiova, S.F. Plummer & D.P. Ramji. (2016) Lactobacillus plantarum CUL66 can impact cholesterol homeostasis in Caco-2 enterocytes . Beneficial Microbes 7:3, pages 443-451.
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Laura G. Gomez-Mascaraque, Russell Cruz Morfin, Rocío Pérez-Masiá, Gloria Sanchez & Amparo Lopez-Rubio. (2016) Optimization of electrospraying conditions for the microencapsulation of probiotics and evaluation of their resistance during storage and in-vitro digestion. LWT - Food Science and Technology 69, pages 438-446.
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Francesca Patrignani, Diana I. Serrazanetti, Julius Maina Mathara, Lorenzo Siroli, Fausto Gardini, Wilhelm H. Holzapfel & Rosalba Lanciotti. (2016) Use of homogenisation pressure to improve quality and functionality of probiotic fermented milks containing Lactobacillus rhamnosus BFE 5264 . International Journal of Dairy Technology 69:2, pages 262-271.
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C. Tomaro-Duchesneau, S. Saha, M. Malhotra, M.L. Jones, L. Rodes & S. Prakash. (2015) Lactobacillus fermentum NCIMB 5221 and NCIMB 2797 as cholesterol-lowering probiotic biotherapeutics: in vitro analysis . Beneficial Microbes 6:6, pages 861-869.
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Axel Kornerup Hansen, Łukasz Krych, Dennis Sandris Nielsen & Camilla Hartmann Friis Hansen. (2015) A Review of Applied Aspects of Dealing with Gut Microbiota Impact on Rodent Models. ILAR Journal 56:2, pages 250-264.
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H.J. Buckenhueskes. 2015. Advances in Fermented Foods and Beverages. Advances in Fermented Foods and Beverages 515 539 .
Ying Huang, Fei Wu, Xiaojun Wang, Yujie Sui, Longfei Yang & Jinfeng Wang. (2013) Characterization of Lactobacillus plantarum Lp27 isolated from Tibetan kefir grains: A potential probiotic bacterium with cholesterol-lowering effects. Journal of Dairy Science 96:5, pages 2816-2825.
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