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Review Article

Carcinogenic mode of action of folpet in mice and evaluation of its relevance to humans

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Pages 531-545 | Received 15 Oct 2009, Accepted 02 Mar 2010, Published online: 03 Jun 2010

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Harm Heusinkveld, Hedwig Braakhuis, Robin Gommans, Phil Botham, Marco Corvaro, Jan Willem van der Laan, Dick Lewis, Federica Madia, Irene Manou, Frédéric Schorsch, Gerrit Wolterink, Ruud Woutersen, Raffaella Corvi, Jyotigna Mehta & Mirjam Luijten. (2020) Towards a mechanism-based approach for the prediction of nongenotoxic carcinogenic potential of agrochemicals. Critical Reviews in Toxicology 50:9, pages 725-739.
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Virunya S. Bhat, Samuel M. Cohen, Elliot B. Gordon, Charles E. Wood, John M. Cullen, Mark A. Harris, Deborah M. Proctor & Chad M. Thompson. (2020) An adverse outcome pathway for small intestinal tumors in mice involving chronic cytotoxicity and regenerative hyperplasia: a case study with hexavalent chromium, captan, and folpet. Critical Reviews in Toxicology 50:8, pages 685-706.
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Chad M. Thompson, Deborah M. Proctor, Mina Suh, Laurie C. Haws, Christopher R. Kirman & Mark A. Harris. (2013) Assessment of the mode of action underlying development of rodent small intestinal tumors following oral exposure to hexavalent chromium and relevance to humans. Critical Reviews in Toxicology 43:3, pages 244-274.
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Elliot Gordon, Samuel M. Cohen & Pramila Singh. (2012) Folpet-induced short term cytotoxic and proliferative changes in the mouse duodenum. Toxicology Mechanisms and Methods 22:1, pages 54-59.
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Gail T. Arce, Elliot B. Gordon, Samuel M. Cohen & Pramila Singh. (2010) Genetic toxicology of folpet and captan. Critical Reviews in Toxicology 40:6, pages 546-574.
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