10,709
Views
257
CrossRef citations to date
0
Altmetric
Review Articles

The Mediator complex and transcription regulation

, &
Pages 575-608 | Received 14 Jun 2013, Accepted 29 Aug 2013, Published online: 03 Oct 2013

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (7)

Matthew D. Galbraith, Heather Bender & Joaquín M. Espinosa. (2019) Therapeutic targeting of transcriptional cyclin-dependent kinases. Transcription 10:2, pages 118-136.
Read now
Vinay Kumar, Mohd Waseem, Nidhi Dwivedi, Sourobh Maji, Angad Kumar & Jitendra K. Thakur. (2018) KIX domain of AtMed15a, a Mediator subunit of Arabidopsis, is required for its interaction with different proteins. Plant Signaling & Behavior 13:2.
Read now
Thomas Eychenne, Michel Werner & Julie Soutourina. (2017) Toward understanding of the mechanisms of Mediator function in vivo: Focus on the preinitiation complex assembly. Transcription 8:5, pages 328-342.
Read now
Jayamani Anandhakumar, Yara W. Moustafa, Surabhi Chowdhary, Amoldeep S. Kainth & David S. Gross. (2016) Evidence for Multiple Mediator Complexes in Yeast Independently Recruited by Activated Heat Shock Factor. Molecular and Cellular Biology 36:14, pages 1943-1960.
Read now
Alison D. Clark, Marieke Oldenbroek & Thomas G. Boyer. (2015) Mediator kinase module and human tumorigenesis. Critical Reviews in Biochemistry and Molecular Biology 50:5, pages 393-426.
Read now
Tristan T. Eifler, Wei Shao, Koen Bartholomeeusen, Koh Fujinaga, Stefanie Jäger, Jeff R. Johnson, Zeping Luo, Nevan J. Krogan & B. Matija Peterlin. (2015) Cyclin-Dependent Kinase 12 Increases 3′ End Processing of Growth Factor-Induced c-FOS Transcripts. Molecular and Cellular Biology 35:2, pages 468-478.
Read now
Emily Paul, Z. Iris Zhu, David Landsman & Randall H. Morse. (2015) Genome-Wide Association of Mediator and RNA Polymerase II in Wild-Type and Mediator Mutant Yeast. Molecular and Cellular Biology 35:1, pages 331-342.
Read now

Articles from other publishers (250)

Zehua Zhou, Jie Liu, Jie Zhang, Huijuan Yan, Tuyong Yi & Won Bo Shim. (2023) Characterization of Fusarium verticillioides Med1 LxxLL Motif Involved in Fumonisin Biosynthesis. Toxins 15:11, pages 652.
Crossref
Nuruliarizki Shinta Pandupuspitasari, Faheem Ahmed Khan, Chunjie Huang, Azhar Ali, Muhammad Rizwan Yousaf, Farwa Shakeel, Ezi Masdia Putri, Windu Negara, Anis Muktiani, Bambang Waluyo Hadi Eko Prasetiyono, Limbang Kustiawan & Dimar Sari Wahyuni. (2023) Recent advances in chromosome capture techniques unraveling 3D genome architecture in germ cells, health, and disease. Functional & Integrative Genomics 23:3.
Crossref
Jana Kalvelage, Lars Wöhlbrand, Robin-Alexander Schoon, Fiona-Marine Zink, Christina Correll, Jennifer Senkler, Holger Eubel, Mona Hoppenrath, Erhard Rhiel, Hans-Peter Braun, Michael Winklhofer, Andreas Klingl & Ralf Rabus. (2023) The enigmatic nucleus of the marine dinoflagellate Prorocentrum cordatum . mSphere 8:4.
Crossref
Kai-Kai Lu, Ru-Feng Song, Jia-Xing Guo, Yu Zhang, Jia-Xin Zuo, Hui-Hui Chen, Cai-Yi Liao, Xiao-Yu Hu, Feng Ren, Ying-Tang Lu & Wen-Cheng Liu. (2023) CycC1;1–WRKY75 complex-mediated transcriptional regulation of SOS1 controls salt stress tolerance in Arabidopsis . The Plant Cell 35:7, pages 2570-2591.
Crossref
Praveen Awasthi, Ajay Kumar Mishra, Tomáš Kocábek, Vishnu Sukumari Nath, Sagarika Mishra, Khaled M. Hazzouri, Naganeeswaran Sudalaimuthuasari, Natasa Stajner, Jernej Jakše, Karel Krofta, Tomáš Hájek & Khaled MA. Amiri. (2023) CRISPR/Cas9-mediated mutagenesis of the mediator complex subunits MED5a and MED5b genes impaired secondary metabolite accumulation in hop (Humulus lupulus). Plant Physiology and Biochemistry, pages 107851.
Crossref
Xiaoguang Chen, Qiongxia Lv & Yumei Liu. (2023) A Comprehensive Genome-Wide Analysis of lncRNA Expression Profile during Hepatic Carcinoma Cell Proliferation Promoted by Phospholipase Cγ2. Cytology and Genetics 57:2, pages 186-196.
Crossref
Lei Deng, Tianxia Yang, Qian Li, Zeqian Chang, Chuanlong Sun, Hongling Jiang, Xianwen Meng, Tingting Huang, Chang-Bao Li, Silin Zhong & Chuanyou Li. (2023) Tomato MED25 regulates fruit ripening by interacting with EIN3-like transcription factors. The Plant Cell 35:3, pages 1038-1057.
Crossref
Rekha Agrawal, Amrita Singh, Jitender Giri, Zoltan Magyar & Jitendra Kumar Thakur. (2023) MEDIATOR SUBUNIT17 is required for transcriptional optimization of root system architecture in Arabidopsis. Plant Physiology.
Crossref
Élie Lambert, Kavindu Puwakdandawa, Yi Fei Tao & François Robert. (2021) From structure to molecular condensates: emerging mechanisms for Mediator function. The FEBS Journal 290:2, pages 286-309.
Crossref
Cunman He, Oliver Berkowitz, Shanshan Hu, Yang Zhao, Kun Qian, Huixia Shou, James Whelan & Yan Wang. (2023) Co-regulation of mitochondrial and chloroplast function: Molecular components and mechanisms. Plant Communications 4:1, pages 100496.
Crossref
Marta Elżbieta Kasprzyk, Marta Kazimierska, Weronika Sura, Agnieszka Dzikiewicz-Krawczyk & Marta Podralska. 2023. Navigating Non-Coding RNA. Navigating Non-Coding RNA 89 138 .
Brian A. Lewis & Stéphan Hardivillé. 2023. Encyclopedia of Cell Biology. Encyclopedia of Cell Biology 606 616 .
Jia-Xing Guo, Ru-Feng Song, Kai-Kai Lu, Yu Zhang, Hui-Hui Chen, Jia-Xin Zuo, Ting-Ting Li, Xue-Feng Li & Wen-Cheng Liu. (2022) CycC1;1 negatively modulates ABA signaling by interacting with and inhibiting ABI5 during seed germination. Plant Physiology 190:4, pages 2812-2827.
Crossref
Harunori Honjoh, Michihiro Tanikawa, Osamu Wada-Hiraike, Katsutoshi Oda, Hirofumi Inaba, Asako Kukita, Yoshiko Kawata, Misako Kusakabe, Saki Tsuchimochi, Ayumi Taguchi, Yuichiro Miyamoto, Kenbun Sone, Tetsushi Tsuruga, Mayuyo Mori-Uchino, Yoko Matsumoto & Yutaka Osuga. (2022) MED1, a novel binding partner of BRCA1, regulates homologous recombination and R-loop processing. Scientific Reports 12:1.
Crossref
Tessa Van Royen, Koen Sedeyn, George D. Moschonas, Wendy Toussaint, Marnik Vuylsteke, Delphi Van Haver, Francis Impens, Sven Eyckerman, Irma Lemmens, Jan Tavernier, Bert Schepens & Xavier Saelens. (2022) An Unexpected Encounter: Respiratory Syncytial Virus Nonstructural Protein 1 Interacts with Mediator Subunit MED25. Journal of Virology 96:19.
Crossref
Emilia Dimitrova, Angelika Feldmann, Robin H. van der Weide, Koen D. Flach, Anna Lastuvkova, Elzo de Wit & Robert J. Klose. (2022) Distinct roles for CKM–Mediator in controlling Polycomb-dependent chromosomal interactions and priming genes for induction. Nature Structural & Molecular Biology 29:10, pages 1000-1010.
Crossref
Joerg E. Braun. 2022. Nucleic Acids in Chemistry and Biology. Nucleic Acids in Chemistry and Biology 224 258 .
Yumin Han, Qian Dong, Tingting Liu, Xiaomin Chen, Chunhong Yu & Yongfeng Zhang. (2022) The novel mechanism of Med12-mediated drug resistance in a TGFBR2-independent manner. Biochemical and Biophysical Research Communications 610, pages 1-7.
Crossref
Jialuo Chen, Su Yang, Baofang Fan, Cheng Zhu & Zhixiang Chen. (2022) The Mediator Complex: A Central Coordinator of Plant Adaptive Responses to Environmental Stresses. International Journal of Molecular Sciences 23:11, pages 6170.
Crossref
Eman Zaffar, Pedro Ferreira, Luis Sanchez-Pulido & Dominik Boos. (2022) The Role of MTBP as a Replication Origin Firing Factor. Biology 11:6, pages 827.
Crossref
Thurston C. Lacalli. (2022) Patterning, From Conifers to Consciousness: Turing’s Theory and Order From Fluctuations. Frontiers in Cell and Developmental Biology 10.
Crossref
Lihao Lin, Minmin Du, Shuyu Li, Chuanlong Sun, Fangming Wu, Lei Deng, Qian Chen & Chuanyou Li. (2022) Mediator complex subunit MED25 physically interacts with DST to regulate spikelet number in rice. Journal of Integrative Plant Biology 64:4, pages 871-883.
Crossref
Lucas Farnung & Seychelle M. Vos. (2022) Assembly of RNA polymerase II transcription initiation complexes. Current Opinion in Structural Biology 73, pages 102335.
Crossref
Benjamin L. Allen, Kim Quach, Taylor Jones, Cecilia B. Levandowski, Christopher C. Ebmeier, Jonathan D. Rubin, Timothy Read, Robin D. Dowell, Alanna Schepartz & Dylan J. Taatjes. (2022) Suppression of p53 response by targeting p53-Mediator binding with a stapled peptide. Cell Reports 39:1, pages 110630.
Crossref
Yujia Jiang, Shijie Hao, Xi Chen, Mengnan Cheng, Jiangshan Xu, Chenghao Li, Huiwen Zheng, Giacomo Volpe, Ao Chen, Sha Liao, Chuanyu Liu, Longqi Liu & Xun Xu. (2022) Spatial Transcriptome Uncovers the Mouse Lung Architectures and Functions. Frontiers in Genetics 13.
Crossref
Li Zhang, Chen Cheng, Jing Li, Lili Wang, Alexander A. Chumanevich, Donald C. Porter, Aleksei Mindich, Svetlana Gorbunova, Igor B. Roninson, Mengqian Chen & Campbell McInnes. (2022) A Selective and Orally Bioavailable Quinoline-6-Carbonitrile-Based Inhibitor of CDK8/19 Mediator Kinase with Tumor-Enriched Pharmacokinetics. Journal of Medicinal Chemistry 65:4, pages 3420-3433.
Crossref
Christiaan J. Stavast, Iris van Zuijen & Stefan J. Erkeland. (2022) MicroRNA-139, an Emerging Gate-Keeper in Various Types of Cancer. Cells 11:5, pages 769.
Crossref
Tessa Van Royen, Iebe Rossey, Koen Sedeyn, Bert Schepens & Xavier Saelens. (2022) How RSV Proteins Join Forces to Overcome the Host Innate Immune Response. Viruses 14:2, pages 419.
Crossref
Helka Göös, Matias Kinnunen, Kari Salokas, Zenglai Tan, Xiaonan Liu, Leena Yadav, Qin Zhang, Gong-Hong Wei & Markku Varjosalo. (2022) Human transcription factor protein interaction networks. Nature Communications 13:1.
Crossref
Srishti Srivastava, Hima Makala, Vikas Sharma, Vaishali Suri, Chitra Sarkar & Ritu Kulshreshtha. (2022) MED12 is overexpressed in glioblastoma patients and serves as an oncogene by targeting the VDR/BCL6/p53 axis. Cellular and Molecular Life Sciences 79:2.
Crossref
Raghuvaran Shanmugam, Mert Burak Ozturk, Joo-Leng Low, Semih Can Akincilar, Joelle Yi Heng Chua, Matan Thangavelu Thangavelu, Giridharan Periyasamy, Ramanuj DasGupta & Vinay Tergaonkar. (2022) Genome-wide screens identify specific drivers of mutant hTERT promoters . Proceedings of the National Academy of Sciences 119:3.
Crossref
Bhuwaneshwar Sharan Mishra, Mohan Sharma & Ashverya Laxmi. (2021) Role of sugar and auxin crosstalk in plant growth and development. Physiologia Plantarum 174:1.
Crossref
Dhanya Sooraj, Claire Sun, Anh Doan, Daniel J. Garama, Marius V. Dannappel, Danxi Zhu, Hui K. Chua, Sylvia Mahara, Wan Amir Wan Hassan, Yeng Kwang Tay, Aleks Guanizo, Daniel Croagh, Zdenka Prodanovic, Daniel J. Gough, Chunhua Wan & Ron Firestein. (2022) MED12 and BRD4 cooperate to sustain cancer growth upon loss of mediator kinase. Molecular Cell 82:1, pages 123-139.e7.
Crossref
Antonio Blanco & Gustavo Blanco. 2022. Medical Biochemistry. Medical Biochemistry 501 534 .
Suleyman Vural, Alida Palmisano, William C. Reinhold, Yves Pommier, Beverly A. Teicher & Julia Krushkal. (2021) Association of expression of epigenetic molecular factors with DNA methylation and sensitivity to chemotherapeutic agents in cancer cell lines. Clinical Epigenetics 13:1.
Crossref
Yali Zhang, Yu Fu, Chenyang Zhang, Linying Jia, Nuo Yao, Yuhao Lin, Yue Dong, Nazira Fatima, Naqash Alam, Rong Wang, Weirong Wang, Liang Bai, Sihai Zhao & Enqi Liu. (2021) MED1 Deficiency in Macrophages Accelerates Intimal Hyperplasia via ROS Generation and Inflammation. Oxidative Medicine and Cellular Longevity 2021, pages 1-19.
Crossref
Michael C Kiritsy, Laurisa M Ankley, Justin Trombley, Gabrielle P Huizinga, Audrey E Lord, Pontus Orning, Roland Elling, Katherine A Fitzgerald & Andrew J Olive. (2021) A genetic screen in macrophages identifies new regulators of IFNγ-inducible MHCII that contribute to T cell activation. eLife 10.
Crossref
Belén Juanes Cortés, José Antonio Vera-Ramos, Ruth C. Lovering, Pascale Gaudet, Astrid Laegreid, Colin Logie, Stefan Schulz, María del Mar Roldán-García, Martin Kuiper & Jesualdo Tomás Fernández-Breis. (2021) Formalization of gene regulation knowledge using ontologies and gene ontology causal activity models. Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms 1864:11-12, pages 194766.
Crossref
Yan Zhang, Chengchen Shi, Weihong Fu, Xiaojing Gu, Ziyang Qi, Weizhong Xu & Gengshou Xia. (2021) Arabidopsis MED18 Interaction With RNA Pol IV and V Subunit NRPD2a in Transcriptional Regulation of Plant Immune Responses. Frontiers in Plant Science 12.
Crossref
Niels Velthuijs, Birgit Meldal, Quinte Geessinck, Pablo Porras, Yulia Medvedeva, Anatoliy Zubritskiy, Sandra Orchard & Colin Logie. (2021) Integration of transcription coregulator complexes with sequence-specific DNA-binding factor interactomes. Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms 1864:10, pages 194749.
Crossref
Anubha Shukla, Srishti Srivastava, Jayant Darokar & Ritu Kulshreshtha. (2020) HIF1α and p53 Regulated MED30, a Mediator Complex Subunit, is Involved in Regulation of Glioblastoma Pathogenesis and Temozolomide Resistance. Cellular and Molecular Neurobiology 41:7, pages 1521-1535.
Crossref
Yanfeng HeShigeo SatoChieri Tomomori-SatoShiyuan ChenZach H. GoodeJoan W. Conaway & Ronald C. Conaway. (2021) Elongin functions as a loading factor for Mediator at ATF6α-regulated ER stress response genes. Proceedings of the National Academy of Sciences 118:39.
Crossref
Haseeb Younis, Muhammad Waqas Anwar, Muhammad Usman Ghani Khan, Aisha Sikandar & Usama Ijaz Bajwa. (2021) A New Sequential Forward Feature Selection (SFFS) Algorithm for Mining Best Topological and Biological Features to Predict Protein Complexes from Protein–Protein Interaction Networks (PPINs). Interdisciplinary Sciences: Computational Life Sciences 13:3, pages 371-388.
Crossref
Paul Gagniuc. 2021. Algorithms in Bioinformatics. Algorithms in Bioinformatics 467 487 .
Paul Gagniuc. 2021. Algorithms in Bioinformatics. Algorithms in Bioinformatics 1 29 .
Mengfan Tang, Guangsheng Pei, Dan Su, Chao Wang, Xu Feng, Mrinal Srivastava, Zhen Chen, Zhongming Zhao & Junjie Chen. (2021) Genome-wide CRISPR screens reveal cyclin C as synthetic survival target of BRCA2. Nucleic Acids Research 49:13, pages 7476-7491.
Crossref
Haining Chen & B. Franklin Pugh. (2021) What do Transcription Factors Interact With?. Journal of Molecular Biology 433:14, pages 166883.
Crossref
Xizi Chen, Xiaotong Yin, Jiabei Li, Zihan Wu, Yilun Qi, Xinxin Wang, Weida Liu & Yanhui Xu. (2021) Structures of the human Mediator and Mediator-bound preinitiation complex. Science 372:6546.
Crossref
Achim P Popp, Johannes Hettich & J Christof M Gebhardt. (2021) Altering transcription factor binding reveals comprehensive transcriptional kinetics of a basic gene. Nucleic Acids Research.
Crossref
Yuri A. Zarate, Tomoko Uehara, Kota Abe, Masayuki Oginuma, Sora Harako, Shizuka Ishitani, Anna-Elina Lehesjoki, Tatjana Bierhals, Katja Kloth, Nadja Ehmke, Denise Horn, Manuel Holtgrewe, Katherine Anderson, David Viskochil, Courtney L. Edgar-Zarate, Maria J. Guillen Sacoto, Rhonda E. Schnur, Michelle M. Morrow, Amarilis Sanchez-Valle, John Pappas, Rachel Rabin, Mikko Muona, Anna-Kaisa Anttonen, Konrad Platzer, Johannes Luppe, Janina Gburek-Augustat, Tadashi Kaname, Nobuhiko Okamoto, Seiji Mizuno, Yusaku Kaido, Yoshiaki Ohkuma, Yutaka Hirose, Tohru Ishitani & Kenjiro Kosaki. (2021) CDK19-related disorder results from both loss-of-function and gain-of-function de novo missense variants. Genetics in Medicine 23:6, pages 1050-1057.
Crossref
Dou Yeon Youn, Alus M. Xiaoli, Haihong Zong, Junichi Okada, Li Liu, Jacob Pessin, Jeffrey E. Pessin & Fajun Yang. (2021) The Mediator complex kinase module is necessary for fructose regulation of liver glycogen levels through induction of glucose-6-phosphatase catalytic subunit (G6pc). Molecular Metabolism 48, pages 101227.
Crossref
Anna Richter, Nina Schoenwaelder, Sina Sender, Christian Junghanss & Claudia Maletzki. (2021) Cyclin-Dependent Kinase Inhibitors in Hematological Malignancies—Current Understanding, (Pre-)Clinical Application and Promising Approaches. Cancers 13:10, pages 2497.
Crossref
Jennifer SelinskiRenate Scheibe. (2021) Central Metabolism in Mammals and Plants as a Hub for Controlling Cell Fate. Antioxidants & Redox Signaling 34:13, pages 1025-1047.
Crossref
Stijn R. van de Plassche & Arjan P. M. de Brouwer. (2021) MED12-Related (Neuro)Developmental Disorders: A Question of Causality. Genes 12:5, pages 663.
Crossref
D. L. Polla, E. J. Bhoj, J. B. G. M. Verheij, J. S. Klein Wassink-Ruiter, A. Reis, C. Deshpande, A. Gregor, K. Hill-Karfe, A. T. Vulto-van Silfhout, R. Pfundt, E. M. H. F. Bongers, H. Hakonarson, S. Berland, G. Gradek, S. Banka, K. Chandler, L. Gompertz, S. C. Huffels, C. T. R. M. Stumpel, R. Wennekes, A. P. A. Stegmann, W. Reardon, E. K. S. M. Leenders, B. B. A. de Vries, D. Li, E. Zackai, N. Ragge, S. A. Lynch, S. Cuddapah, H. van Bokhoven, C. Zweier & A. P. M. de Brouwer. (2020) De novo variants in MED12 cause X-linked syndromic neurodevelopmental disorders in 18 females. Genetics in Medicine 23:4, pages 645-652.
Crossref
Hai Liu & Michael P. Timko. (2021) Jasmonic Acid Signaling and Molecular Crosstalk with Other Phytohormones. International Journal of Molecular Sciences 22:6, pages 2914.
Crossref
Chuqin Huang, Rui Xu, Samuel Liégeois, Di Chen, Zi Li & Dominique Ferrandon. (2021) Differential Requirements for Mediator Complex Subunits in Drosophila melanogaster Host Defense Against Fungal and Bacterial Pathogens. Frontiers in Immunology 11.
Crossref
Kévin M. André, Eliet H. Sipos & Julie Soutourina. (2021) Mediator Roles Going Beyond Transcription. Trends in Genetics 37:3, pages 224-234.
Crossref
Dan Wu, Zhaoyan Zhang, Xing Chen, Yaoyao Yan & Xinhua Liu. (2021) Angel or Devil ? - CDK8 as the new drug target. European Journal of Medicinal Chemistry 213, pages 113043.
Crossref
Miłosz Roliński, Nicola Pietro Montaldo, Merdane Ezgi Aksu, Sarah L Fordyce Martin, Alessandro Brambilla, Nicolas Kunath, Jostein Johansen, Sten Even Erlandsen, Nina-Beate Liabbak, Kristin Rian, Magnar Bjørås, Pål Sætrom & Barbara van Loon. (2021) Loss of Mediator complex subunit 13 (MED13) promotes resistance to alkylation through cyclin D1 upregulation. Nucleic Acids Research 49:3, pages 1470-1484.
Crossref
Rekha Agrawal, Fajkus Jiří & Jitendra K Thakur. (2021) The kinase module of the Mediator complex: an important signalling processor for the development and survival of plants. Journal of Experimental Botany 72:2, pages 224-240.
Crossref
Catherine A. Vaughan, Shilpa Singh, Mark A. Subler, Jolene J. Windle, Kazushi Inoue, Elizabeth A. Fry, Raghavendra Pillappa, Steven R. Grossman, Brad Windle, W. Andrew Yeudall, Swati Palit Deb & Sumitra Deb. (2021) The oncogenicity of tumor-derived mutant p53 is enhanced by the recruitment of PLK3. Nature Communications 12:1.
Crossref
Sarika Kondra, Titli Sarkar, Vijay Raghavan & Wu Xu. (2021) Development of a TSR-Based Method for Protein 3-D Structural Comparison With Its Applications to Protein Classification and Motif Discovery. Frontiers in Chemistry 8.
Crossref
Katrine Bugge, Lasse Staby, Edoardo Salladini, Rasmus G. Falbe-Hansen, Birthe B. Kragelund & Karen Skriver. (2021) αα-Hub domains and intrinsically disordered proteins: A decisive combo. Journal of Biological Chemistry 296, pages 100226.
Crossref
Rohan Bhardwaj, Jitendra Kumar Thakur & Shailesh Kumar. (2021) MedProDB: A database of Mediator proteins. Computational and Structural Biotechnology Journal 19, pages 4165-4176.
Crossref
Yuuri Yasuoka & Masanori Taira. 2021. Amphibian Models of Development and Disease. Amphibian Models of Development and Disease 113 166 .
Lizabeth A. Allison & Vincent R. Roggero. 2021. Nuclear Receptors. Nuclear Receptors 37 66 .
Shubham Kumar Sinha & Koppolu Raja Rajesh Kumar. 2021. Jasmonates and Salicylates Signaling in Plants. Jasmonates and Salicylates Signaling in Plants 265 279 .
Heeyoun Bunch. 2021. Heat Shock Proteins in Inflammatory Diseases. Heat Shock Proteins in Inflammatory Diseases 489 508 .
Matteo Costacurta, Stephin J Vervoort, Simon J Hogg, Benjamin P Martin, Ricky W Johnstone & Jake Shortt. (2020) Whole genome CRISPR screening identifies TOP2B as a potential target for IMiD sensitization in multiple myeloma. Haematologica 106:7, pages 2013-2017.
Crossref
Martin Stortz, Adali Pecci, Diego M. Presman & Valeria Levi. (2020) Unraveling the molecular interactions involved in phase separation of glucocorticoid receptor. BMC Biology 18:1.
Crossref
Chao He, Hong-Yu Zhang, Yong-Xin Zhang, Pei Fu, Li-Li You, Wen-Bo Xiao, Zhao-Hai Wang, Hai-Yan Song, Ying-Jin Huang & Jiang-Lin Liao. (2020) Cytosine methylations in the promoter regions of genes involved in the cellular oxidation equilibrium pathways affect rice heat tolerance. BMC Genomics 21:1.
Crossref
Jianyang Liu, Yanning Wang & Youfa Cheng. (2020) The ESCRT‐I components VPS28A and VPS28B are essential for auxin‐mediated plant development. The Plant Journal 104:6, pages 1617-1634.
Crossref
Liu Peng, En-Min Li & Li-Yan Xu. (2020) From start to end: Phase separation and transcriptional regulation. Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms 1863:12, pages 194641.
Crossref
Ross D. Jones, Yili Qian, Velia Siciliano, Breanna DiAndreth, Jin Huh, Ron Weiss & Domitilla Del Vecchio. (2020) An endoribonuclease-based feedforward controller for decoupling resource-limited genetic modules in mammalian cells. Nature Communications 11:1.
Crossref
Soma Dash, Shachi Bhatt, Lisa L. Sandell, Christopher W. Seidel, Youngwook Ahn, Robb E. Krumlauf & Paul A. Trainor. (2020) The Mediator Subunit, Med23 Is Required for Embryonic Survival and Regulation of Canonical WNT Signaling During Cranial Ganglia Development. Frontiers in Physiology 11.
Crossref
Wu Xu, Xiao-Jun Xie, Ali K. Faust, Mengmeng Liu, Xiao Li, Feng Chen, Ashlin A. Naquin, Avery C. Walton, Peter W. Kishbaugh & Jun-Yuan Ji. (2020) All-Atomic Molecular Dynamic Studies of Human and Drosophila CDK8: Insights into Their Kinase Domains, the LXXLL Motifs, and Drug Binding Site. International Journal of Molecular Sciences 21:20, pages 7511.
Crossref
Qingzhe Zhai, Lei Deng & Chuanyou Li. (2020) Mediator subunit MED25: at the nexus of jasmonate signaling. Current Opinion in Plant Biology 57, pages 78-86.
Crossref
Jia Bian, Marius Dannappel, Chunhua Wan & Ron Firestein. (2020) Transcriptional Regulation of Wnt/β-Catenin Pathway in Colorectal Cancer. Cells 9:9, pages 2125.
Crossref
Fanglin Zheng, Yanli Cao, Renfei Yang, Lei Wang, Xinxing Lv, Weixin Zhang, Xiangfeng Meng & Weifeng Liu. (2020) Trichoderma reesei XYR1 activates cellulase gene expression via interaction with the Mediator subunit TrGAL11 to recruit RNA polymerase II. PLOS Genetics 16:9, pages e1008979.
Crossref
Robert J. Rooney. (2020) Multiple domains in the 50 kDa form of E4F1 regulate promoter-specific repression and E1A trans-activation. Gene 754, pages 144882.
Crossref
Tanner M. Tessier, Katelyn M. MacNeil & Joe S. Mymryk. (2020) Piggybacking on Classical Import and Other Non-Classical Mechanisms of Nuclear Import Appear Highly Prevalent within the Human Proteome. Biology 9:8, pages 188.
Crossref
Robert M Yarrington, Yaxin Yu, Chao Yan, Lu Bai & David J Stillman. (2020) A Role for Mediator Core in Limiting Coactivator Recruitment in Saccharomyces cerevisiae . Genetics 215:2, pages 407-420.
Crossref
Chinmayee Panda, Xin Li, Amanda Wager, Han‐Yi Chen & Xu Li. (2020) An importin‐beta‐like protein mediates lignin‐modification‐induced dwarfism in Arabidopsis. The Plant Journal 102:6, pages 1281-1293.
Crossref
Dan Li & Jianlong Wang. (2020) Ribosome heterogeneity in stem cells and development. Journal of Cell Biology 219:6.
Crossref
Xiao Li, Mengmeng Liu, Xingjie Ren, Nicolas Loncle, Qun Wang, Rajitha-Udakara-Sampath Hemba-Waduge, Stephen H. Yu, Muriel Boube, Henri-Marc G. Bourbon, Jian-Quan Ni & Jun-Yuan Ji. (2020) The Mediator CDK8-Cyclin C complex modulates Dpp signaling in Drosophila by stimulating Mad-dependent transcription. PLOS Genetics 16:5, pages e1008832.
Crossref
Eirik Solum, Trond Vidar Hansen, Reidun Aesoy & Lars Herfindal. (2020) New CDK8 inhibitors as potential anti-leukemic agents – Design, synthesis and biological evaluation. Bioorganic & Medicinal Chemistry 28:10, pages 115461.
Crossref
Alina-Andreea Zimta, Adrian Bogdan Tigu, Cornelia Braicu, Cristina Stefan, Calin Ionescu & Ioana Berindan-Neagoe. (2020) An Emerging Class of Long Non-coding RNA With Oncogenic Role Arises From the snoRNA Host Genes. Frontiers in Oncology 10.
Crossref
Angelika Feldmann, Emilia Dimitrova, Alexander Kenney, Anna Lastuvkova & Robert J Klose. (2020) CDK-Mediator and FBXL19 prime developmental genes for activation by promoting atypical regulatory interactions. Nucleic Acids Research 48:6, pages 2942-2955.
Crossref
Matthew R. Femia, Rochelle M. Evans, Jibo Zhang, Xiaopeng Sun, Caroline J. Lebegue, Vincent R. Roggero & Lizabeth A. Allison. (2019) Mediator subunit MED1 modulates intranuclear dynamics of the thyroid hormone receptor. Journal of Cellular Biochemistry 121:4, pages 2909-2926.
Crossref
Jennifer E.G. Gallagher, Suk Lan Ser, Michael C. Ayers, Casey Nassif & Amaury Pupo. (2020) The Polymorphic PolyQ Tail Protein of the Mediator Complex, Med15, Regulates the Variable Response to Diverse Stresses. International Journal of Molecular Sciences 21:5, pages 1894.
Crossref
Feng Li, Lin Gao & Bingbo Wang. (2020) Detection of Driver Modules with Rarely Mutated Genes in Cancers. IEEE/ACM Transactions on Computational Biology and Bioinformatics 17:2, pages 390-401.
Crossref
Yaolai Wang & Feng Liu. (2020) Transcription apparatus: A dancer on a rope. Acta Physica Sinica 69:24, pages 248702.
Crossref
Vatsal Patel, Deyin Xing, Michael Feely & John Kenneth Schoolmeester. (2020) Smooth Muscle Tumors of the Visceral Adnexal and Uterine Ligaments and Adnexal Connective Tissue: A Clinicopathologic Study of 67 Cases. International Journal of Gynecological Pathology 39:1, pages 55-67.
Crossref
Zahra Motahari, Sally Ann Moody, Thomas Michael Maynard & Anthony-Samuel LaMantia. (2019) In the line-up: deleted genes associated with DiGeorge/22q11.2 deletion syndrome: are they all suspects?. Journal of Neurodevelopmental Disorders 11:1.
Crossref
Aneta Tarczewska & Beata Greb-Markiewicz. (2019) The Significance of the Intrinsically Disordered Regions for the Functions of the bHLH Transcription Factors. International Journal of Molecular Sciences 20:21, pages 5306.
Crossref
Nidhi Dwivedi, Sourobh Maji, Mohd Waseem, Pallabi Thakur, Vinay Kumar, Swarup K. Parida & Jitendra K. Thakur. (2019) The Mediator subunit OsMED15a is a transcriptional co-regulator of seed size/weight–modulating genes in rice. Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms 1862:10, pages 194432.
Crossref
Adrien Georges, Diyavarshini Gopaul, Cyril Denby Wilkes, Nathalie Giordanengo Aiach, Elizaveta Novikova, Marie-Bénédicte Barrault, Olivier Alibert & Julie Soutourina. (2019) Functional interplay between Mediator and RNA polymerase II in Rad2/XPG loading to the chromatin. Nucleic Acids Research 47:17, pages 8988-9004.
Crossref
David G. Cooper & Jan S. Fassler. (2019) Med15: Glutamine-Rich Mediator Subunit with Potential for Plasticity. Trends in Biochemical Sciences 44:9, pages 737-751.
Crossref
Yun Dai, Fengyan Jin, Wei Wu & Shaji K. Kumar. (2019) Cell cycle regulation and hematologic malignancies. Blood Science 1:1, pages 34-43.
Crossref
Mathew Dittmann, Grzegorz Buczkowski, Michael Scharf & Gary Bennett. (2019) Gene expression changes in response to field-to-lab transition in the Argentine ant, Linepithema humile. Journal of Insect Physiology 117, pages 103901.
Crossref
Qingzhe Zhai & Chuanyou Li. (2019) The plant Mediator complex and its role in jasmonate signaling. Journal of Experimental Botany 70:13, pages 3415-3424.
Crossref
Jyoti Garg, Alejandro Saettone, Syed Nabeel-Shah, Matthew Cadorin, Marcelo Ponce, Susanna Marquez, Shuye Pu, Jack Greenblatt, Jean-Philippe Lambert, Ronald E. Pearlman & Jeffrey Fillingham. (2019) The Med31 Conserved Component of the Divergent Mediator Complex in Tetrahymena thermophila Participates in Developmental Regulation. Current Biology 29:14, pages 2371-2379.e6.
Crossref
Marti Quevedo, Lize Meert, Mike R. Dekker, Dick H. W. Dekkers, Johannes H. Brandsma, Debbie L. C. van den Berg, Zeliha Ozgür, Wilfred F. J. van IJcken, Jeroen Demmers, Maarten Fornerod & Raymond A. Poot. (2019) Mediator complex interaction partners organize the transcriptional network that defines neural stem cells. Nature Communications 10:1.
Crossref
Kun Xiong, Alex K. Lancaster, Mark L. Siegal & Joanna Masel. (2019) Feed-forward regulation adaptively evolves via dynamics rather than topology when there is intrinsic noise. Nature Communications 10:1.
Crossref
Feda H. Hamdan & Steven A. Johnsen. (2019) Perturbing Enhancer Activity in Cancer Therapy. Cancers 11:5, pages 634.
Crossref
Sourobh Maji, Pradeep Dahiya, Mohd Waseem, Nidhi Dwivedi, Divya S Bhat, Tanvir H Dar & Jitendra K Thakur. (2019) Interaction map of Arabidopsis Mediator complex expounding its topology. Nucleic Acids Research 47:8, pages 3904-3920.
Crossref
Eduardo Calpena, Alexia Hervieu, Teresa Kaserer, Sigrid M.A. Swagemakers, Jacqueline A.C. Goos, Olajumoke Popoola, Maria Jesus Ortiz-Ruiz, Tina Barbaro-Dieber, Lucy Bownass, Eva H. Brilstra, Elise Brimble, Nicola Foulds, Theresa A. Grebe, Aster V.E. Harder, Melissa M. Lees, Kristin G. Monaghan, Ruth A. Newbury-Ecob, Kai-Ren Ong, Deborah Osio, Francis Jeshira Reynoso Santos, Maura R.Z. Ruzhnikov, Aida Telegrafi, Ellen van Binsbergen, Marieke F. van Dooren, Peter J. van der Spek, Julian Blagg, Stephen R.F. Twigg, Irene M.J. Mathijssen, Paul A. Clarke & Andrew O.M. Wilkie. (2019) De Novo Missense Substitutions in the Gene Encoding CDK8, a Regulator of the Mediator Complex, Cause a Syndromic Developmental Disorder. The American Journal of Human Genetics 104:4, pages 709-720.
Crossref
Zoya Avramova. (2018) Defence‐related priming and responses to recurring drought: Two manifestations of plant transcriptional memory mediated by the ABA and JA signalling pathways. Plant, Cell & Environment 42:3, pages 983-997.
Crossref
Alexis Verger, Didier Monté & Vincent Villeret. (2019) Twenty years of Mediator complex structural studies. Biochemical Society Transactions 47:1, pages 399-410.
Crossref
M. P. Rubtsova, D. P. Vasilkova, M. A. Moshareva, A. N. Malyavko, M. B. Meerson, T. S. Zatsepin, Y. V. Naraykina, A. V. Beletsky, N. V. Ravin & O. A. Dontsova. (2019) Integrator is a key component of human telomerase RNA biogenesis. Scientific Reports 9:1.
Crossref
Duane D. Hall, Kathryn M. Spitler & Chad E. Grueter. (2019) Disruption of cardiac Med1 inhibits RNA polymerase II promoter occupancy and promotes chromatin remodeling. American Journal of Physiology-Heart and Circulatory Physiology 316:2, pages H314-H325.
Crossref
Marius Volker Dannappel, Dhanya Sooraj, Jia Jian Loh & Ron Firestein. (2019) Molecular and in vivo Functions of the CDK8 and CDK19 Kinase Modules. Frontiers in Cell and Developmental Biology 6.
Crossref
Xuan Shu, Zejun Dong, Liuhanghang Cheng & Shenyou Shu. (2019) DNA hypermethylation of Fgf16 and Tbx22 associated with cleft palate during palatal fusion. Journal of Applied Oral Science 27.
Crossref
P. Yilma, M. Kostrouchová, P. Talacko, V. Kostrouchová, D. Kostrouch, P. Novák & Marta Kostrouchová. (2019) Proteomic Interactome of C. elegans Mediator Complex Subunit 28 (MDT-28) Reveals Predominant Association with a Restricted Set of Core Mediator Subunits and an Affinity to Additional Structural and Enzymatic Proteins. Folia Biologica 65:5-6, pages 203-211.
Crossref
Bindu Pandey, Pravin Prakash, Praveen Chandra Verma & Rakesh Srivastava. 2019. Current Developments in Biotechnology and Bioengineering. Current Developments in Biotechnology and Bioengineering 235 255 .
Xiaoyan Ma, Daphne Ezer, Boris Adryan & Tim J. Stevens. (2018) Canonical and single-cell Hi-C reveal distinct chromatin interaction sub-networks of mammalian transcription factors. Genome Biology 19:1.
Crossref
Xinsheng Gao, Xiao-Jun Xie, Fu-Ning Hsu, Xiao Li, Mengmeng Liu, Rajitha-Udakara-Sampath Hemba-Waduge, Wu Xu & Jun-Yuan Ji. (2018) CDK8 mediates the dietary effects on developmental transition in Drosophila. Developmental Biology 444:2, pages 62-70.
Crossref
Ying Fan, Sumana Sanyal & Roberto Bruzzone. (2018) Breaking Bad: How Viruses Subvert the Cell Cycle. Frontiers in Cellular and Infection Microbiology 8.
Crossref
Maggie M. Balas, Allison M. Porman, Kirk C. Hansen & Aaron M. Johnson. (2018) SILAC-MS Profiling of Reconstituted Human Chromatin Platforms for the Study of Transcription and RNA Regulation. Journal of Proteome Research 17:10, pages 3475-3484.
Crossref
Wenxiu Ma, Lifang Zou, JI Zhiyuan, XU Xiameng, XU Zhengyin, Yangyang Yang, James R. Alfano & Gongyou Chen. (2018) Xanthomonas oryzae pv. oryzae TALE proteins recruit OsTFIIAγ1 to compensate for the absence of OsTFIIAγ5 in bacterial blight in rice . Molecular Plant Pathology 19:10, pages 2248-2262.
Crossref
Julia Segert, Isabelle Schneider, Ina M. Berger, Wolfgang Rottbauer & Steffen Just. (2018) Mediator complex subunit Med12 regulates cardiac jelly development and AV valve formation in zebrafish. Progress in Biophysics and Molecular Biology 138, pages 20-31.
Crossref
Samra Sardar, Katrine Kanne & Åsa Andersson. (2018) Analysis of Polymorphisms in the Mediator Complex Subunit 13-like (Med13L) Gene in the Context of Immune Function and Development of Experimental Arthritis. Archivum Immunologiae et Therapiae Experimentalis 66:5, pages 365-377.
Crossref
Whitney L Dolan & Clint Chapple. (2018) Transcriptome Analysis of Four Arabidopsis thaliana Mediator Tail Mutants Reveals Overlapping and Unique Functions in Gene Regulation . G3 Genes|Genomes|Genetics 8:9, pages 3093-3108.
Crossref
Thomas M. Harper & Dylan J. Taatjes. (2018) The complex structure and function of Mediator. Journal of Biological Chemistry 293:36, pages 13778-13785.
Crossref
Hui Liu, Lulin Kong, Yanli Qi, Xiulai Chen & Liming Liu. (2018) Candida glabrata Med3 Plays a Role in Altering Cell Size and Budding Index To Coordinate Cell Growth. Applied and Environmental Microbiology 84:15.
Crossref
Naomi R. Genuth & Maria Barna. (2018) Heterogeneity and specialized functions of translation machinery: from genes to organisms. Nature Reviews Genetics 19:7, pages 431-452.
Crossref
Stephen Philip, Malika Kumarasiri, Theodosia Teo, Mingfeng Yu & Shudong Wang. (2017) Cyclin-Dependent Kinase 8: A New Hope in Targeted Cancer Therapy?. Journal of Medicinal Chemistry 61:12, pages 5073-5092.
Crossref
Xiaoyue ZhangWenkun ZhouQian Chen, Mingming FangShuangshuang Zheng, Ben Scheres & Chuanyou Li. (2018) Mediator subunit MED31 is required for radial patterning of Arabidopsis roots . Proceedings of the National Academy of Sciences 115:24.
Crossref
Emilia Dimitrova, Takashi Kondo, Angelika Feldmann, Manabu Nakayama, Yoko Koseki, Rebecca Konietzny, Benedikt M Kessler, Haruhiko Koseki & Robert J Klose. (2018) FBXL19 recruits CDK-Mediator to CpG islands of developmental genes priming them for activation during lineage commitment. eLife 7.
Crossref
Lot Snijders Blok, Susan M. Hiatt, Kevin M. Bowling, Jeremy W. Prokop, Krysta L. Engel, J. Nicholas Cochran, E. Martina Bebin, Emilia K. Bijlsma, Claudia A. L. Ruivenkamp, Paulien Terhal, Marleen E. H. Simon, Rosemarie Smith, Jane A. Hurst, Heather McLaughlin, Richard Person, Amy Crunk, Michael F. Wangler, Haley Streff, Joseph D. Symonds, Sameer M. Zuberi, Katherine S. Elliott, Victoria R. Sanders, Abigail Masunga, Robert J. Hopkin, Holly A. Dubbs, Xilma R. Ortiz-Gonzalez, Rolph Pfundt, Han G. Brunner, Simon E. Fisher, Tjitske Kleefstra & Gregory M. Cooper. (2018) De novo mutations in MED13, a component of the Mediator complex, are associated with a novel neurodevelopmental disorder. Human Genetics 137:5, pages 375-388.
Crossref
E. V. Putlyaev, A. N. Ibragimov, L. A. Lebedeva, P. G. Georgiev & Y. V. Shidlovskii. (2018) Structure and Functions of the Mediator Complex. Biochemistry (Moscow) 83:4, pages 423-436.
Crossref
Julie Soutourina. (2017) Transcription regulation by the Mediator complex. Nature Reviews Molecular Cell Biology 19:4, pages 262-274.
Crossref
Dorine Jeanne Mariëtte du Mee, Maxim Ivanov, Joseph Paul Parker, Stephen Buratowski & Sebastian Marquardt. (2018) Efficient termination of nuclear lncRNA transcription promotes mitochondrial genome maintenance. eLife 7.
Crossref
Aida Barreiro-Alonso, Mónica Lamas-Maceiras, Esperanza M Cerdán & Ángel Vizoso-Vázquez. (2018) The HMGB protein Ixr1 interacts with Ssn8 and Tdh3 involved in transcriptional regulation. FEMS Yeast Research 18:2.
Crossref
Bernard Perbal. (2018) The concept of the CCN protein family revisited: a centralized coordination network. Journal of Cell Communication and Signaling 12:1, pages 3-12.
Crossref
Daria M. Fedoseeva, Olga V. Kretova, Maria A. Gorbacheva & Nickolai A. Tchurikov. (2018) Individual effects of the copia and gypsy enhancer and insulator on chromatin marks, eRNA synthesis, and binding of insulator proteins in transfected genetic constructs. Gene 641, pages 151-160.
Crossref
Amol Ranjan & Suraiya A. Ansari. (2018) Therapeutic potential of Mediator complex subunits in metabolic diseases. Biochimie 144, pages 41-49.
Crossref
Rakesh Srivastava, Krishan Mohan Rai & Rashmi Srivastava. 2018. Biosynthetic Technology and Environmental Challenges. Biosynthetic Technology and Environmental Challenges 51 72 .
Victor Tang, Kevin Otto & Warren SeeringInez Y. Oh & Cristina de Guzman Strong. 2018. Executive Decision Synthesis. Executive Decision Synthesis 231 262 .
Xu Zhang, Yuting Yang, Jiake Zou, Yun Chen, Qibin Wu, Jinlong Guo, Youxiong Que & Liping Xu. (2017) ScMED7, a sugarcane mediator subunit gene, acts as a regulator of plant immunity and is responsive to diverse stress and hormone treatments. Molecular Genetics and Genomics 292:6, pages 1363-1375.
Crossref
Zhongle Liu & Lawrence C. Myers. (2017) Candida albicans Swi/Snf and Mediator Complexes Differentially Regulate Mrr1-Induced MDR1 Expression and Fluconazole Resistance . Antimicrobial Agents and Chemotherapy 61:11.
Crossref
Zhongle Liu & Lawrence C. Myers. (2017) Mediator Tail Module Is Required for Tac1-Activated CDR1 Expression and Azole Resistance in Candida albicans . Antimicrobial Agents and Chemotherapy 61:11.
Crossref
Matthew D. Galbraith, Zdenek Andrysik, Ahwan Pandey, Maria Hoh, Elizabeth A. Bonner, Amanda A. Hill, Kelly D. Sullivan & Joaquín M. Espinosa. (2017) CDK8 Kinase Activity Promotes Glycolysis. Cell Reports 21:6, pages 1495-1506.
Crossref
Chunpeng AnLin LiQingzhe Zhai, Yanrong YouLei DengFangming WuRong ChenHongling JiangHang Wang, Qian Chen & Chuanyou Li. (2017) Mediator subunit MED25 links the jasmonate receptor to transcriptionally active chromatin. Proceedings of the National Academy of Sciences 114:42.
Crossref
Célia Jeronimo & François Robert. (2017) The Mediator Complex: At the Nexus of RNA Polymerase II Transcription. Trends in Cell Biology 27:10, pages 765-783.
Crossref
Zoé Lens, François-Xavier Cantrelle, Riccardo Peruzzini, Xavier Hanoulle, Frédérique Dewitte, Elisabeth Ferreira, Jean-Luc Baert, Didier Monté, Marc Aumercier, Vincent Villeret, Alexis Verger & Isabelle Landrieu. (2017) Solution Structure of the N-Terminal Domain of Mediator Subunit MED26 and Molecular Characterization of Its Interaction with EAF1 and TAF7. Journal of Molecular Biology 429:20, pages 3043-3055.
Crossref
Simon L. Currie, Jedediah J. Doane, Kathryn S. Evans, Niraja Bhachech, Bethany J. Madison, Desmond K.W. Lau, Lawrence P. McIntosh, Jack J. Skalicky, Kathleen A. Clark & Barbara J. Graves. (2017) ETV4 and AP1 Transcription Factors Form Multivalent Interactions with three Sites on the MED25 Activator-Interacting Domain. Journal of Molecular Biology 429:20, pages 2975-2995.
Crossref
Yanli Qi, Hui Liu, Jiayin Yu, Xiulai Chen & Liming Liu. (2017) Med15B Regulates Acid Stress Response and Tolerance in Candida glabrata by Altering Membrane Lipid Composition. Applied and Environmental Microbiology 83:18.
Crossref
Xiaobao Lin, Yanli Qi, Dongni Yan, Hui Liu, Xiulai Chen & Liming Liu. (2017) CgMED3 Changes Membrane Sterol Composition To Help Candida glabrata Tolerate Low-pH Stress . Applied and Environmental Microbiology 83:17.
Crossref
Reza Asadollahi, Markus Zweier, Laura Gogoll, Raphael Schiffmann, Heinrich Sticht, Katharina Steindl & Anita Rauch. (2017) Genotype-phenotype evaluation of MED13L defects in the light of a novel truncating and a recurrent missense mutation. European Journal of Medical Genetics 60:9, pages 451-464.
Crossref
Duane D. Hall, Jessica M. Ponce, Biyi Chen, Kathryn M. Spitler, Adrianne Alexia, Gavin Y. Oudit, Long-Sheng Song & Chad E. Grueter. (2017) Ectopic expression of Cdk8 induces eccentric hypertrophy and heart failure. JCI Insight 2:15.
Crossref
Kedryn K. Baskin, Catherine A. Makarewich, Susan M. DeLeon, Wenduo Ye, Beibei Chen, Nadine Beetz, Heinrich Schrewe, Rhonda Bassel-Duby & Eric N. Olson. (2017) MED12 regulates a transcriptional network of calcium-handling genes in the heart. JCI Insight 2:14.
Crossref
Kemal Kazan. (2017) The Multitalented MEDIATOR25. Frontiers in Plant Science 8.
Crossref
Markéta Kostrouchová, David Kostrouch, Ahmed A. Chughtai, Filip Kaššák, Jan P. Novotný, Veronika Kostrouchová, Aleš Benda, Michael W. Krause, Vladimír Saudek, Marta Kostrouchová & Zdeněk Kostrouch. (2017) The nematode homologue of Mediator complex subunit 28, F28F8.5, is a critical regulator of C. elegans development . PeerJ 5, pages e3390.
Crossref
Eva NogalesRobert K. Louder & Yuan He. (2017) Structural Insights into the Eukaryotic Transcription Initiation Machinery. Annual Review of Biophysics 46:1, pages 59-83.
Crossref
Steven R. Whittaker, Aurélie Mallinger, Paul Workman & Paul A. Clarke. (2017) Inhibitors of cyclin-dependent kinases as cancer therapeutics. Pharmacology & Therapeutics 173, pages 83-105.
Crossref
Nidhi Dwivedi, Vinay Kumar & Jitendra K. Thakur. 2017. Mechanism of Plant Hormone Signaling under Stress. Mechanism of Plant Hormone Signaling under Stress 285 317 .
Johannes Brägelmann, Niklas Klümper, Anne Offermann, Anne von Mässenhausen, Diana Böhm, Mario Deng, Angela Queisser, Christine Sanders, Isabella Syring, Axel S. Merseburger, Wenzel Vogel, Elisabeth Sievers, Ignacija Vlasic, Jessica Carlsson, Ove Andrén, Peter Brossart, Stefan Duensing, Maria A. Svensson, David Adler, Jutta Kirfel & Sven Perner. (2017) Pan-Cancer Analysis of the Mediator Complex Transcriptome Identifies CDK19 and CDK8 as Therapeutic Targets in Advanced Prostate Cancer. Clinical Cancer Research 23:7, pages 1829-1840.
Crossref
Koji Ono, Hiroshi Banno, Masanori Okaniwa, Takaharu Hirayama, Naoki Iwamura, Yukiko Hikichi, Saomi Murai, Maki Hasegawa, Yuka Hasegawa, Kazuko Yonemori, Akito Hata, Kazunobu Aoyama & Douglas R. Cary. (2017) Design and synthesis of selective CDK8/19 dual inhibitors: Discovery of 4,5-dihydrothieno[3′,4′:3,4]benzo[1,2- d ]isothiazole derivatives. Bioorganic & Medicinal Chemistry 25:8, pages 2336-2350.
Crossref
Regina Andrade Menezes, Catarina Pimentel, Ana Rita Courelas Silva, Catarina Amaral, Jawad Merhej, Frédéric Devaux & Claudina Rodrigues-Pousada. (2017) Mediator, SWI/SNF and SAGA complexes regulate Yap8-dependent transcriptional activation of ACR2 in response to arsenate. Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms 1860:4, pages 472-481.
Crossref
Niklas Klümper, Isabella Syring, Wenzel Vogel, Doris Schmidt, Stefan C. Müller, Jörg Ellinger, David Adler, Johannes Brägelmann & Sven Perner. (2017) Mediator Complex Subunit MED1 Protein Expression Is Decreased during Bladder Cancer Progression. Frontiers in Medicine 4.
Crossref
Seiji Yamamoto, Tomoko Hagihara, Yoshiyuki Horiuchi, Akira Okui, Shotaro Wani, Tokuyuki Yoshida, Takao Inoue, Aki Tanaka, Takashi Ito, Yutaka Hirose & Yoshiaki Ohkuma. (2017) Mediator cyclin-dependent kinases upregulate transcription of inflammatory genes in cooperation with NF-κB and C/EBPβ on stimulation of Toll-like receptor 9. Genes to Cells 22:3, pages 265-276.
Crossref
Henriette Uthe, Jens T. Vanselow & Andreas Schlosser. (2017) Proteomic Analysis of the Mediator Complex Interactome in Saccharomyces cerevisiae. Scientific Reports 7:1.
Crossref
Erin M. Arms, Zhanghang Yan & Dina A. St.Clair. (2017) Differential Transcriptional Regulation in Roots of Tomato Near-Isogenic Lines in Response to Rapid-Onset Water Stress. Frontiers in Plant Science 8.
Crossref
Antonio Blanco & Gustavo Blanco. 2017. Medical Biochemistry. Medical Biochemistry 465 492 .
M. Wassef & R. Margueron. 2017. Chromatin Regulation and Dynamics. Chromatin Regulation and Dynamics 165 189 .
Joachim Griesenbeck, Herbert Tschochner & Dina Grohmann. 2017. Macromolecular Protein Complexes. Macromolecular Protein Complexes 225 270 .
Paul A Clarke, Maria-Jesus Ortiz-Ruiz, Robert TePoele, Olajumoke Adeniji-Popoola, Gary Box, Will Court, Stephanie Czasch, Samer El Bawab, Christina Esdar, Ken Ewan, Sharon Gowan, Alexis De Haven Brandon, Phillip Hewitt, Stephen M Hobbs, Wolfgang Kaufmann, Aurélie Mallinger, Florence Raynaud, Toby Roe, Felix Rohdich, Kai Schiemann, Stephanie Simon, Richard Schneider, Melanie Valenti, Stefan Weigt, Julian Blagg, Andree Blaukat, Trevor C Dale, Suzanne A Eccles, Stefan Hecht, Klaus Urbahns, Paul Workman & Dirk Wienke. (2016) Assessing the mechanism and therapeutic potential of modulators of the human Mediator complex-associated protein kinases. eLife 5.
Crossref
Han-Tsang Wu, Yi-Chih Kuo, Jung-Jyh Hung, Chi-Hung Huang, Wei-Yi Chen, Teh-Ying Chou, Yeh Chen, Yi-Ju Chen, Yu-Ju Chen, Wei-Chung Cheng, Shu-Chun Teng & Kou-Juey Wu. (2016) K63-polyubiquitinated HAUSP deubiquitinates HIF-1α and dictates H3K56 acetylation promoting hypoxia-induced tumour progression. Nature Communications 7:1.
Crossref
Akhi Akhter & Emanuel Rosonina. (2016) Chromatin Association of Gcn4 Is Limited by Post-translational Modifications Triggered by its DNA-Binding in Saccharomyces cerevisiae . Genetics 204:4, pages 1433-1445.
Crossref
Ning Liu & Zoya Avramova. (2016) Molecular mechanism of the priming by jasmonic acid of specific dehydration stress response genes in Arabidopsis. Epigenetics & Chromatin 9:1.
Crossref
Manuel Buendía-Monreal & C. Stewart Gillmor. (2016) Mediator: A key regulator of plant development. Developmental Biology 419:1, pages 7-18.
Crossref
Célia Jeronimo, Marie-France Langelier, Alain R. Bataille, John M. Pascal, B. Franklin Pugh & François Robert. (2016) Tail and Kinase Modules Differently Regulate Core Mediator Recruitment and Function In Vivo. Molecular Cell 64:3, pages 455-466.
Crossref
Thaleia Papadopoulou & Holger Richly. (2016) On-site remodeling at chromatin: How multiprotein complexes are rebuilt during DNA repair and transcriptional activation. BioEssays 38:11, pages 1130-1140.
Crossref
Yun Sol Jo, Min Sung Kim, Nam Jin Yoo & Sug Hyung Lee. (2016) Frameshift Mutation of MED25, a Transcription Regulator, and its Mutational Heterogeneity in Colorectal Cancers. Pathology & Oncology Research 22:4, pages 875-876.
Crossref
Yun Sol Jo, Mi Ryoung Choi, Sang Yong Song, Min Sung Kim, Nam Jin Yoo & Sug Hyung Lee. (2016) Frameshift Mutations of HSPA4 and MED13 in Gastric and Colorectal Cancers. Pathology & Oncology Research 22:4, pages 769-772.
Crossref
Babajan Banaganapalli, Kaleemuddin Mohammed, Imran Ali Khan, Jumana Y. Al-Aama, Ramu Elango & Noor Ahmad Shaik. (2016) A Computational Protein Phenotype Prediction Approach to Analyze the Deleterious Mutations of Human MED12 Gene. Journal of Cellular Biochemistry 117:9, pages 2023-2035.
Crossref
Jing Wang, Xiangming Liu, Zhongmin Jiang, Lili Li, Zhigang Cui, Yuan Gao, Di Kong & Xiaozhi Liu. (2016) A novel method to limit breast cancer stem cells in states of quiescence, proliferation or differentiation: Use of gel stress in combination with stem cell growth factors. Oncology Letters 12:2, pages 1355-1360.
Crossref
Tory Chhun, Suet Yen Chong, Bong Soo Park, Eriko Chi Cheng Wong, Jun-Lin Yin, Mijung Kim & Nam-Hai Chua. (2016) HSI2 Repressor Recruits MED13 and HDA6 to Down-Regulate Seed Maturation Gene Expression Directly During Arabidopsis Early Seedling Growth. Plant and Cell Physiology 57:8, pages 1689-1706.
Crossref
Amanda Dugan, Rachel Pricer, Micah Katz & Anna K. Mapp. (2016) TRIC: Capturing the direct cellular targets of promoter-bound transcriptional activators. Protein Science 25:8, pages 1371-1377.
Crossref
Katjana Tantale, Florian Mueller, Alja Kozulic-Pirher, Annick Lesne, Jean-Marc Victor, Marie-Cécile Robert, Serena Capozi, Racha Chouaib, Volker Bäcker, Julio Mateos-Langerak, Xavier Darzacq, Christophe Zimmer, Eugenia Basyuk & Edouard Bertrand. (2016) A single-molecule view of transcription reveals convoys of RNA polymerases and multi-scale bursting. Nature Communications 7:1.
Crossref
Alejandro Chavez, Marcelle Tuttle, Benjamin W Pruitt, Ben Ewen-Campen, Raj Chari, Dmitry Ter-Ovanesyan, Sabina J Haque, Ryan J Cecchi, Emma J K Kowal, Joanna Buchthal, Benjamin E Housden, Norbert Perrimon, James J Collins & George Church. (2016) Comparison of Cas9 activators in multiple species. Nature Methods 13:7, pages 563-567.
Crossref
Scott E. LeBlanc, Qiong Wu, Pallavi Lamba, Saïd Sif & Anthony N. Imbalzano. (2016) Promoter–enhancer looping at the PPARγ2 locus during adipogenic differentiation requires the Prmt5 methyltransferase. Nucleic Acids Research 44:11, pages 5133-5147.
Crossref
Anna Kołaczkowska & Marcin Kołaczkowski. (2016) Drug resistance mechanisms and their regulation in non- albicans Candida species . Journal of Antimicrobial Chemotherapy 71:6, pages 1438-1450.
Crossref
Kapil Gupta, Duygu Sari-Ak, Matthias Haffke, Simon Trowitzsch & Imre Berger. (2016) Zooming in on Transcription Preinitiation. Journal of Molecular Biology 428:12, pages 2581-2591.
Crossref
Célia Jeronimo, Pierre Collin & François Robert. (2016) The RNA Polymerase II CTD: The Increasing Complexity of a Low-Complexity Protein Domain. Journal of Molecular Biology 428:12, pages 2607-2622.
Crossref
Clemens Plaschka, Kayo Nozawa & Patrick Cramer. (2016) Mediator Architecture and RNA Polymerase II Interaction. Journal of Molecular Biology 428:12, pages 2569-2574.
Crossref
Alena Pance. (2016) Oct-1, to go or not to go? That is the PolII question. Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms 1859:6, pages 820-824.
Crossref
Steven Hahn & Stephen Buratowski. (2016) Snapshots of transcription initiation. Nature 533:7603, pages 331-332.
Crossref
Timothy M. Griffin, Kenneth M. Humphries, Michael Kinter, Hui-Ying Lim & Luke I. Szweda. (2016) Nutrient sensing and utilization: Getting to the heart of metabolic flexibility. Biochimie 124, pages 74-83.
Crossref
Naveen Malik, Nidhi Dwivedi, Ashok K. Singh, Swarup K. Parida, Pinky Agarwal, Jitendra K. Thakur & Akhilesh K. Tyagi. (2016) An Integrated Genomic Strategy Delineates Candidate Mediator Genes Regulating Grain Size and Weight in Rice. Scientific Reports 6:1.
Crossref
Xing Hua, Paula L. Hyland, Jing Huang, Lei Song, Bin Zhu, Neil E. Caporaso, Maria Teresa Landi, Nilanjan Chatterjee & Jianxin Shi. (2016) MEGSA: A Powerful and Flexible Framework for Analyzing Mutual Exclusivity of Tumor Mutations. The American Journal of Human Genetics 98:3, pages 442-455.
Crossref

Displaying 200 of 257 citing articles. Use the download link below to view the full list of citing articles.

Download full citations list