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Original Article

Genomic and phenotypic characterization of nurse-like cells that promote drug resistance in chronic lymphocytic leukemia

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Pages 1404-1406 | Published online: 23 Jun 2011

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (6)

Ishaque S. Mohammad, Ke Lin, Melanie Oates, Umair T. Khan, Jan Burger, Andrew R. Pettitt & Jianguo Zhuang. (2021) Development of a cell-line model to mimic the pro-survival effect of nurse-like cells in chronic lymphocytic leukemia. Leukemia & Lymphoma 62:1, pages 45-57.
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Melinda Burgess, Yu Chen Enya Chen, Sally Mapp, Peter Mollee, Devinder Gill & Nicholas A. Saunders. (2020) Identifying an obinutuzumab resistant subpopulation of monocyte-derived-macrophages from patients with CLL. Leukemia & Lymphoma 61:11, pages 2738-2742.
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Cristina Bagacean, Ciprian Tomuleasa, Adrian Tempescul, Ravnit Grewal, Wesley H. Brooks, Christian Berthou & Yves Renaudineau. (2019) Apoptotic resistance in chronic lymphocytic leukemia and therapeutic perspectives. Critical Reviews in Clinical Laboratory Sciences 56:5, pages 321-332.
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Marie Tosolini, Christelle Algans, Frédéric Pont, Bernard Ycart & Jean-Jacques Fournié. (2016) Large-scale microarray profiling reveals four stages of immune escape in non-Hodgkin lymphomas. OncoImmunology 5:7.
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Line Nederby, Anne S. Roug, Signe S. Knudsen, Anni Skovbo, Eigil Kjeldsen, Holger J. Moller & Marianne Hokland. (2015) Soluble CD163 as a prognostic biomarker in B-cell chronic lymphocytic leukemia. Leukemia & Lymphoma 56:11, pages 3219-3221.
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Frédéric Boissard, Jean-Jacques Fournié, Camille Laurent, Mary Poupot & Loïc Ysebaert. (2015) Nurse like cells: chronic lymphocytic leukemia associated macrophages. Leukemia & Lymphoma 56:5, pages 1570-1572.
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Articles from other publishers (28)

Marcin Domagala, Loïc Ysebaert, Laetitia Ligat, Frederic Lopez, Jean-Jacques Fournié, Camille Laurent & Mary Poupot. (2021) IL-10 Rescues CLL Survival through Repolarization of Inflammatory Nurse-like Cells. Cancers 14:1, pages 16.
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Yu-Chen Enya Chen, Melinda Burgess, Sally Mapp, Peter Mollee, Devinder Gill, Antje Blumenthal & Nicholas A. Saunders. (2021) SIRPα Suppresses Response to Therapeutic Antibodies by Nurse Like Cells From Chronic Lymphocytic Leukemia Patients. Frontiers in Immunology 11.
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Ekaterina Kim, Elisa ten Hacken, Mariela Sivina, Astrid Clarke, Philip A. Thompson, Nitin Jain, Alessandra Ferrajoli, Zeev Estrov, Michael J. Keating, William G. Wierda, Kapil N. Bhalla & Jan A. Burger. (2019) The BET inhibitor GS-5829 targets chronic lymphocytic leukemia cells and their supportive microenvironment. Leukemia 34:6, pages 1588-1598.
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Yoshikane Kikushige. (2020) Pathogenesis of chronic lymphocytic leukemia and the development of novel therapeutic strategies. Journal of Clinical and Experimental Hematopathology 60:4, pages 146-158.
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Uta E. Höpken & Armin Rehm. (2019) Targeting the Tumor Microenvironment of Leukemia and Lymphoma. Trends in Cancer 5:6, pages 351-364.
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Bola S. Hanna, Selcen Öztürk & Martina Seiffert. (2019) Beyond bystanders: Myeloid cells in chronic lymphocytic leukemia. Molecular Immunology 110, pages 77-87.
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Paolo Giannoni, Franco Fais, Giovanna Cutrona & Daniela Totero. (2019) Hepatocyte Growth Factor: A Microenvironmental Resource for Leukemic Cell Growth. International Journal of Molecular Sciences 20:2, pages 292.
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David K. Edwards V, David Tyler Sweeney, Hibery Ho, Christopher A. Eide, Angela Rofelty, Anupriya Agarwal, Selina Qiuying Liu, Alexey V. Danilov, Patrice Lee, David Chantry, Shannon K. McWeeney, Brian J. Druker, Jeffrey W. Tyner, Stephen E. Spurgeon & Marc M. Loriaux. (2018) Targeting of colony-stimulating factor 1 receptor (CSF1R) in the CLL microenvironment yields antineoplastic activity in primary patient samples. Oncotarget 9:37, pages 24576-24589.
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Y.C.E. Chen, S. Mapp, A. Blumenthal, M.L. Burgess, R. Mazzieri, S.R. Mattarollo, P. Mollee, D. Gill & N.A. Saunders. (2017) The duality of macrophage function in chronic lymphocytic leukaemia. Biochimica et Biophysica Acta (BBA) - Reviews on Cancer 1868:1, pages 176-182.
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M Burgess, S Mapp, R Mazzieri, C Cheung, L Chambers, S R Mattarollo, P Mollee, D Gill & N A Saunders. (2016) Increased FcγRIIB dominance contributes to the emergence of resistance to therapeutic antibodies in chronic lymphocytic leukaemia patients. Oncogene 36:17, pages 2366-2376.
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Avery Polk, Ye Lu, Tianjiao Wang, Erlene Seymour, Nathanael G. Bailey, Jack W. Singer, Philip S. Boonstra, Megan S. Lim, Sami Malek & Ryan A. Wilcox. (2016) Colony-Stimulating Factor-1 Receptor Is Required for Nurse-like Cell Survival in Chronic Lymphocytic Leukemia. Clinical Cancer Research 22:24, pages 6118-6128.
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Stefania Fiorcari, Rossana Maffei, Valentina Audrito, Silvia Martinelli, Elisa ten Hacken, Patrizia Zucchini, Giulia Grisendi, Leonardo Potenza, Mario Luppi, Jan A. Burger, Silvia Deaglio & Roberto Marasca. (2016) Ibrutinib modifies the function of monocyte/macrophage population in chronic lymphocytic leukemia. Oncotarget 7:40, pages 65968-65981.
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Marcel Gätjen, Franziska Brand, Michael Grau, Kerstin Gerlach, Ralph Kettritz, Jörg Westermann, Ioannis Anagnostopoulos, Peter Lenz, Georg Lenz, Uta E. Höpken & Armin Rehm. (2016) Splenic Marginal Zone Granulocytes Acquire an Accentuated Neutrophil B-Cell Helper Phenotype in Chronic Lymphocytic Leukemia. Cancer Research 76:18, pages 5253-5265.
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Shalini Gautam, Kavin Fatehchand, Saranya Elavazhagan, Brenda F. Reader, Li Ren, Xiaokui Mo, John C. Byrd, Susheela Tridandapani & Jonathan P. Butchar. (2016) Reprogramming Nurse-like Cells with Interferon γ to Interrupt Chronic Lymphocytic Leukemia Cell Survival. Journal of Biological Chemistry 291:27, pages 14356-14362.
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B S Hanna, F McClanahan, H Yazdanparast, N Zaborsky, V Kalter, P M Rößner, A Benner, C Dürr, A Egle, J G Gribben, P Lichter & M Seiffert. (2015) Depletion of CLL-associated patrolling monocytes and macrophages controls disease development and repairs immune dysfunction in vivo. Leukemia 30:3, pages 570-579.
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M. Burgess, J.J. Ellis, S. Mapp, P. Mollee, R. Mazzieri, S.R. Mattarollo, D. Gill & N.A. Saunders. (2016) Transcriptomic analysis of monocytes and macrophages derived from CLL patients which display differing abilities to respond to therapeutic antibody immune complexes. Genomics Data 7, pages 4-6.
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Elisa ten Hacken & Jan A. Burger. (2016) Microenvironment interactions and B-cell receptor signaling in Chronic Lymphocytic Leukemia: Implications for disease pathogenesis and treatment. Biochimica et Biophysica Acta (BBA) - Molecular Cell Research 1863:3, pages 401-413.
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F Boissard, C Laurent, A G Ramsay, A Quillet-Mary, J-J Fournié, M Poupot & L Ysebaert. (2016) Nurse-like cells impact on disease progression in chronic lymphocytic leukemia. Blood Cancer Journal 6:1, pages e381-e381.
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Rossana Maffei, Elisabetta Colaci, Stefania Fiorcari, Silvia Martinelli, Leonardo Potenza, Mario Luppi & Roberto Marasca. (2016) Lenalidomide in chronic lymphocytic leukemia: the present and future in the era of tyrosine kinase inhibitors. Critical Reviews in Oncology/Hematology 97, pages 291-302.
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Rossana Maffei, Stefania Fiorcari, Silvia Martinelli, Leonardo Potenza, Mario Luppi & Roberto Marasca. (2015) Targeting neoplastic B cells and harnessing microenvironment: the “double face” of ibrutinib and idelalisib. Journal of Hematology & Oncology 8:1.
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F Boissard, J-J Fournié, A Quillet-Mary, L Ysebaert & M Poupot. (2015) Nurse-like cells mediate ibrutinib resistance in chronic lymphocytic leukemia patients. Blood Cancer Journal 5:10, pages e355-e355.
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Simone Bürgler, Aleix Gimeno, Anna Parente-Ribes, Dong Wang, Audun Os, Stephen Devereux, Peter Jebsen, Bjarne Bogen, Geir E. Tjønnfjord & Ludvig A. Munthe. (2015) Chronic Lymphocytic Leukemia Cells Express CD38 in Response to Th1 Cell–Derived IFN-γ by a T-bet–Dependent Mechanism. The Journal of Immunology 194:2, pages 827-835.
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Valentina AudritoSara SerraDavide BrusaFrancesca MazzolaFrancesca ArrugaTiziana VaisittiMarta CosciaRossana MaffeiDavide RossiTao WangGiorgio InghiramiMenico RizziGianluca GaidanoJoe G. N. Garcia, Cynthia WolbergerNadia Raffaelli & Silvia Deaglio. (2015) Extracellular nicotinamide phosphoribosyltransferase (NAMPT) promotes M2 macrophage polarization in chronic lymphocytic leukemia. Blood 125:1, pages 111-123.
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Li Jia, Andrew Clear, Feng-Ting Liu, Janet Matthews, Nadiha Uddin, Aine McCarthy, Elena Hoxha, Catherine Durance, Sameena Iqbal & John G. Gribben. (2014) Extracellular HMGB1 promotes differentiation of nurse-like cells in chronic lymphocytic leukemia. Blood 123:11, pages 1709-1719.
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Christine E. Cutucache. (2013) Tumor-induced host immunosuppression: Special focus on CLL. International Immunopharmacology 17:1, pages 35-41.
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Agata A. Filip, Bogumi?a Cise?Dorota Koczkodaj, Ewa W?sik-Szczepanek, Tomasz Piersiak & Anna Dmoszy?ska. (2013) Circulating microenvironment of CLL: Are nurse-like cells related to tumor-associated macrophages?. Blood Cells, Molecules, and Diseases 50:4, pages 263-270.
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Angela SchulzClaudia DürrThorsten Zenz, Hartmut Döhner, Stephan Stilgenbauer, Peter LichterMartina Seiffert. (2013) Lenalidomide reduces survival of chronic lymphocytic leukemia cells in primary cocultures by altering the myeloid microenvironment. Blood 121:13, pages 2503-2511.
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Steven D. Mittelman & Anna Butturini. 2012. Energy Balance and Hematologic Malignancies. Energy Balance and Hematologic Malignancies 47 69 .

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