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Leukemia & Lymphoma Volume 54, 2013 - Issue 5
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Letter

Bax and Bak are required for apogossypolone, a BH3-mimetic, induced apoptosis in chronic lymphocytic leukemia cells

Kumudha BalakrishnanDepartment of Experimental Therapeutics
,
Sumesh AggarwalDepartment of Experimental Therapeutics
,
William WierdaDepartment of Leukemia, The University of Texas M. D. Anderson Cancer Center, Houston, TX, USA
&
Varsha GandhiDepartment of Experimental Therapeutics;Department of Leukemia, The University of Texas M. D. Anderson Cancer Center, Houston, TX, USACorrespondence[email protected]
Pages 1097-1100 | Received 03 Jul 2012, Accepted 30 Jul 2012, Published online: 04 Sep 2012

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Shadia Zaman, Rui Wang & Varsha Gandhi. (2014) Targeting the apoptosis pathway in hematologic malignancies. Leukemia & Lymphoma 55:9, pages 1980-1992.
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Articles from other publishers (6)

Natalie Yan Li Ngoi, Clarice Choong, Joanne Lee, Gregory Bellot, Andrea LA Wong, Boon Cher Goh & Shazib Pervaiz. (2020) Targeting Mitochondrial Apoptosis to Overcome Treatment Resistance in Cancer. Cancers 12:3, pages 574.
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Ruinian Zheng, Kexu Chen, Yu Zhang, Jie Huang, Fengrong Shi, Gang Wu & Senming Wang. (2017) Apogossypolone induces apoptosis and autophagy in nasopharyngeal carcinoma cells in an in vitro and in vivo study. Oncology Letters 14:1, pages 751-757.
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Jie Ji, Benigno C. Valdez, Yang Li, Yan Liu, Esmeralda C. Teo, Yago Nieto, Richard E. Champlin & Borje S. Andersson. (2016) Cladribine, gemcitabine, busulfan, and SAHA combination as a potential pretransplant conditioning regimen for lymphomas: A preclinical study. Experimental Hematology 44:6, pages 458-465.
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Jens Mani, Stefan Vallo, Stefanie Rakel, Patrick Antonietti, Florian Gessler, Roman Blaheta, Georg Bartsch, Martin Michaelis, Jindrich Cinatl, Axel Haferkamp & Donat Kögel. (2015) Chemoresistance is associated with increased cytoprotective autophagy and diminished apoptosis in bladder cancer cells treated with the BH3 mimetic (−)-Gossypol (AT-101). BMC Cancer 15:1.
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Kumudha Balakrishnan & Varsha Gandhi. (2013) Bcl-2 antagonists: a proof of concept for CLL therapy. Investigational New Drugs 31:5, pages 1384-1394.
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Christian Billard. (2013) BH3 Mimetics: Status of the Field and New Developments. Molecular Cancer Therapeutics 12:9, pages 1691-1700.
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