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Original Articles: Research

Sorafenib induces paradoxical phosphorylation of the extracellular signal-regulated kinase pathway in acute myeloid leukemia cells lacking FLT3-ITD mutation

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Pages 2690-2698 | Received 19 Jul 2014, Accepted 20 Dec 2014, Published online: 03 Mar 2015

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Qixin Sun, Bingyi Wu, Fanyi Meng, Qianqian Yao, Zhiwei Huang, Jianhui Xu & Zhigang Zhu. (2023) Sorafenib regulates c-CBL gene-mediated chemoresistance in acute myeloid leukemia cells. Hematology 28:1.
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Articles from other publishers (5)

Franziska Schmidt, Miriam Erlacher, Charlotte Niemeyer, Dirk Reinhardt & Jan-Henning Klusmann. (2022) Leukoreductive response to the combination of sorafenib and chemotherapy in hyperleukocytosis of FLT3-ITD mutated pediatric AML. Frontiers in Pediatrics 10.
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Suresh Gopi Kalathil, Alan Hutson, Joseph Barbi, Renuka Iyer & Yasmin Thanavala. (2019) Augmentation of IFN-γ+ CD8+ T cell responses correlates with survival of HCC patients on sorafenib therapy. JCI Insight 4:15.
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Amir Noeparast, Philippe Giron, Alfiah Noor, Rajendra Bahadur Shahi, Sylvia De Brakeleer, Carolien Eggermont, Hugo Vandenplas, Bram Boeckx, Diether Lambrechts, Jacques De Grève & Erik Teugels. (2019) CRAF mutations in lung cancer can be oncogenic and predict sensitivity to combined type II RAF and MEK inhibition. Oncogene 38:31, pages 5933-5941.
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Leticia Serrano-Oviedo, Marta Ortega-Muelas, Jesús García-Cano, María Ll. Valero, Francisco J. Cimas, Raquel Pascual-Serra, Diego M. Fernandez-Aroca, Olga Roche, María J. Ruiz-Hidalgo, Borja Belandia, José M. Giménez-Bachs, Antonio S. Salinas & Ricardo Sanchez-Prieto. (2018) Autophagic cell death associated to Sorafenib in renal cell carcinoma is mediated through Akt inhibition in an ERK1/2 independent fashion. PLOS ONE 13:7, pages e0200878.
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Lifang Luo, Lijing Cai, Laibang Luo, Zhimou Tang & Xiaohui Meng. (2018) Silencing activating transcription factor 2 promotes the anticancer activity of sorafenib in hepatocellular carcinoma cells. Molecular Medicine Reports.
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