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Research Article

Development of Serratiopeptidase and Metronidazole Based Alginate Microspheres for Wound Healing

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Pages 44-50 | Published online: 17 Jun 2010

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Azizeh Rahmani Del Bakhshayesh, Nasim Annabi, Rovshan Khalilov, Abolfazl Akbarzadeh, Mohammad Samiei, Effat Alizadeh, Mohammadreza Alizadeh-Ghodsi, Soodabeh Davaran & Azadeh Montaseri. (2018) Recent advances on biomedical applications of scaffolds in wound healing and dermal tissue engineering. Artificial Cells, Nanomedicine, and Biotechnology 46:4, pages 691-705.
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Sandeep Kumar, Asim K. Jana, Isha Dhamija & Mithu Maiti. (2014) Chitosan-assisted immobilization of serratiopeptidase on magnetic nanoparticles, characterization and its target delivery. Journal of Drug Targeting 22:2, pages 123-137.
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Deependra Singh & Manju Rawat Singh. (2012) Development of antibiotic and debriding enzyme-loaded PLGA microspheres entrapped in PVA-gelatin hydrogel for complete wound management. Artificial Cells, Blood Substitutes, and Biotechnology 40:5, pages 345-353.
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Articles from other publishers (16)

Mohit Kumar, Devesh Kumar, Yogesh Garg, Syed Mahmood, Shruti Chopra & Amit Bhatia. (2023) Marine-derived polysaccharides and their therapeutic potential in wound healing application - A review. International Journal of Biological Macromolecules 253, pages 127331.
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Dinesh Kumar, Diksha Verma & Vikrant Abbot. (2023) A review on pharmaceutical, pharmacological and chemical aspects of serratiopeptidase as anti-inflammatory agent. Materials Today: Proceedings.
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Sreelakshmi R. Nair & Subathra Devi. C. (2022) Serratiopeptidase: An integrated View of Multifaceted Therapeutic Enzyme. Biomolecules 12:10, pages 1468.
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Kawther Khalid Ahmed & Amaraporn Wongrakpanich. (2022) Particles-based medicated wound dressings: a comprehensive review. Therapeutic Delivery 13:10, pages 489-505.
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Elham Sharifi, Javad Rahbar Shahrouzi, Hoda Jafarizadeh-Malmiri, Somayyeh Ghaffari & Ali Baradar Khoshfetrat. (2021) Optimization of microencapsulation of metronidazole in alginate microbeads for purpose of controlled release. Polymer Bulletin 79:10, pages 8883-8903.
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Shenghai Shen, Xiaowen Chen, Zhewen Shen & Hao Chen. (2021) Marine Polysaccharides for Wound Dressings Application: An Overview. Pharmaceutics 13:10, pages 1666.
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Swati B. Jadhav, Neha Shah, Ankit Rathi, Vic Rathi & Abhijit Rathi. (2020) Serratiopeptidase: Insights into the therapeutic applications. Biotechnology Reports 28, pages e00544.
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M.R. El-Aassar, Omar M. Ibrahim, Moustafa M.G. Fouda, Nagham G. El-Beheri & Mona M. Agwa. (2020) Wound healing of nanofiber comprising Polygalacturonic/Hyaluronic acid embedded silver nanoparticles: In-vitro and in-vivo studies. Carbohydrate Polymers 238, pages 116175.
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Amar Deepak, Amit K. Goyal & Goutam Rath. (2018) Development and Characterization of Novel Medicated Nanofiber for the Treatment of Periodontitis. AAPS PharmSciTech 19:8, pages 3687-3697.
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Karuppusamy Shanmugapriya, Hyejin Kim, Periaswamy Sivagnanam Saravana, Byung-Soo Chun & Hyun Wook Kang. (2018) Fabrication of multifunctional chitosan-based nanocomposite film with rapid healing and antibacterial effect for wound management. International Journal of Biological Macromolecules 118, pages 1713-1725.
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Selvarajan Ethiraj & Shreya Gopinath. (2017) Production, purification, characterization, immobilization, and application of Serrapeptase: a review. Frontiers in Biology 12:5, pages 333-348.
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Quan Liu, Yuchen Huang, Yong Lan, Qinhua Zuo, Chenghua Li, Yi Zhang, Rui Guo & Wei Xue. (2017) Acceleration of skin regeneration in full-thickness burns by incorporation of bFGF-loaded alginate microspheres into a CMCS-PVA hydrogel. Journal of Tissue Engineering and Regenerative Medicine 11:5, pages 1562-1573.
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Mohammad Z. Albanna, Aleksander Skardal, Idris B. El-Amin & James H. Holmes. 2015. Encyclopedia of Biomedical Polymers and Polymeric Biomaterials. Encyclopedia of Biomedical Polymers and Polymeric Biomaterials 7335 7350 .
Praveen Kumar Gaur, Shikha Mishra & Meenakshi Bajpai. (2014) Formulation and evaluation of controlled-release of telmisartan microspheres: In vitro/in vivo study. Journal of Food and Drug Analysis 22:4, pages 542-548.
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Sandeep Kumar, Asim K. Jana, Mithu Maiti & Isha Dhamija. (2014) Carbodiimide-mediated immobilization of serratiopeptidase on amino-, carboxyl-functionalized magnetic nanoparticles and characterization for target delivery. Journal of Nanoparticle Research 16:2.
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Sandeep Kumar, Asim K. Jana, Isha Dhamija, Yashpaul Singla & Mithu Maiti. (2013) Preparation, characterization and targeted delivery of serratiopeptidase immobilized on amino-functionalized magnetic nanoparticles. European Journal of Pharmaceutics and Biopharmaceutics 85:3, pages 413-426.
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