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Research Article

Methylation-mediated gene silencing of suppressor of cytokine signaling-1 (SOCS-1) gene in esophageal squamous cell carcinoma patients of Kashmir valley

Pages 147-156 | Received 19 Oct 2010, Accepted 09 Jan 2011, Published online: 09 Mar 2011

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Wanli Yang, Yu Han, Xinhui Zhao, Lili Duan, Wei Zhou, Xiaoqian Wang, Gaokai Shi, Yinggang Che, Yujie Zhang, Jinqiang Liu, Hongwei Zhang, Qingchuan Zhao, Liu Hong & Daiming Fan. (2019) Advances in prognostic biomarkers for esophageal cancer. Expert Review of Molecular Diagnostics 19:2, pages 109-119.
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Neha Singh, Showket Hussain, Mausumi Bharadwaj, Nandita Kakkar, S. K. Singh & Ranbir C. Sobti. (2012) Overexpression of signal transducer and activator of transcription (STAT-3 and STAT-5) transcription factors and alteration of suppressor of cytokine signaling (SOCS-1) protein in prostate cancer. Journal of Receptors and Signal Transduction 32:6, pages 321-327.
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Articles from other publishers (19)

Jiesheng Rong, Rui Pu, Hongru Sun, Yupeng Liu, Tian Tian, Haoran Bi, Tingting Xia, Lei Zhang, Yuanyuan Zhang, Yashuang Zhao & Lin Zhu. (2023) Association between the methylation of CpG islands in JAK-STAT pathway-related genes and colorectal cancer. Gene 868, pages 147357.
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Sameer Ahmad Guru, Mamta Pervin Sumi, Rashid Mir, Mirza Masroor Ali Beg, Bidhan Chandra koner & Alpana Saxena. (2022) Aberrant hydroxymethylation in promoter CpG regions of genes related to the cell cycle and apoptosis characterizes advanced chronic myeloid leukemia disease, poor imatinib respondents and poor survival. BMC Cancer 22:1.
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Xiao-hu Zhou, Hao Xu, Chang Xu, Ying-cai Yan, Lin-shi Zhang, Qiang Sun, Wei-lin Wang & Yan-jun Shi. (2022) Hepatocellular carcinoma-derived exosomal miRNA-761 regulates the tumor microenvironment by targeting the SOCS2/JAK2/STAT3 pathway. World Journal of Emergency Medicine 13:5, pages 379.
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Fatemeh Khaledi & Sorayya Ghasemi. (2022) A Review on Epigenetic Effects of Environmental Factors Causing and Inhibiting Cancer. Current Molecular Medicine 22:1, pages 8-24.
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Hong Zhu, Huizi Zhao, Songbing Xu, Yuan Zhang, Yuhao Ding, Jun Li, Cheng Huang & Taotao Ma. (2021) Sennoside A alleviates inflammatory responses by inhibiting the hypermethylation of SOCS1 in CCl4-induced liver fibrosis. Pharmacological Research 174, pages 105926.
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Ke Sun & Guangping Zhang. (2019) Long noncoding RNA CASC2 suppresses esophageal squamous cell carcinoma progression by increasing SOCS1 expression. Cell & Bioscience 9:1.
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Jie Ying, Xiaoyan Qiu, Yu Lu & Miaomiao Zhang. (2019) SOCS1 and its Potential Clinical Role in Tumor. Pathology & Oncology Research 25:4, pages 1295-1301.
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Yuetao Lv, Ge Song & Peng Li. (2018) Correlation of SOCS‑1 gene with onset and prognosis of breast cancer. Oncology Letters.
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Jie Ma, Xian-Bin Wang, Rui Li, Shu-Hong Xuan, Fang Wang, Xin-Hua Li, Zhi-Ping Zhang, Lu Tan & Lian Li. (2017) RNAi-mediated TCF-3 gene silencing inhibits proliferation of Eca-109 esophageal cancer cells by inducing apoptosis . Bioscience Reports 37:6.
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Takahito Sugase, Tsuyoshi Takahashi, Satoshi Serada, Rie Nakatsuka, Minoru Fujimoto, Tomoharu Ohkawara, Hisashi Hara, Takahiko Nishigaki, Koji Tanaka, Yasuhiro Miyazaki, Tomoki Makino, Yukinori Kurokawa, Makoto Yamasaki, Kiyokazu Nakajima, Shuji Takiguchi, Tadamitsu Kishimoto, Masaki Mori, Yuichiro Doki & Tetsuji Naka. (2017) Suppressor of cytokine signaling-1 gene therapy induces potent antitumor effect in patient-derived esophageal squamous cell carcinoma xenograft mice. International Journal of Cancer 140:11, pages 2608-2621.
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Cécile Naudin, Clément Chevalier & Serge Roche. (2016) The role of small adaptor proteins in the control of oncogenic signaling driven by tyrosine kinases in human cancer. Oncotarget 7:10, pages 11033-11055.
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Neha Singh, Showket Hussain, Nandita Kakkar, Shrawan K. Singh, Ranbir C. Sobti & Mausumi Bharadwaj. (2015) Implication of high risk Human papillomavirus HR-HPV infection in prostate cancer in Indian population- A pioneering case-control analysis. Scientific Reports 5:1.
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Jian-Jun Zhang, Yu-Chen Fan, Ze-Hua Zhao, Yang Yang, Cheng-Yun Dou, Shuai Gao & Kai Wang. (2014) Prognoses of patients with acute-on-chronic hepatitis B liver failure are closely associated with altered SOCS1 mRNA expression and cytokine production following glucocorticoid treatment. Cellular & Molecular Immunology 11:4, pages 396-404.
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H. A. HARDEFELDT, M. R. COX & G. D. ESLICK. (2014) Association between human papillomavirus (HPV) and oesophageal squamous cell carcinoma: a meta-analysis. Epidemiology and Infection 142:6, pages 1119-1137.
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Walid Sasi, Anup K. Sharma & Kefah Mokbel. (2014) The Role of Suppressors of Cytokine Signalling in Human Neoplasms. Molecular Biology International 2014, pages 1-24.
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Chang Cheng, Cheng Huang, Tao-Tao Ma, Er-Bao Bian, Yong He, Lei Zhang & Jun Li. (2014) SOCS1 hypermethylation mediated by DNMT1 is associated with lipopolysaccharide-induced inflammatory cytokines in macrophages. Toxicology Letters 225:3, pages 488-497.
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Mario PoljakBoštjan J Kocjan & Lea Hošnjak. (2014) Role of human papillomaviruses in esophageal carcinoma: an updated systematic review from 1982 to 2013. Future Virology 9:1, pages 69-86.
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Yoshifumi Baba, Masayuki Watanabe & Hideo Baba. (2013) A review of the alterations in DNA methylation in esophageal squamous cell carcinoma. Surgery Today 43:12, pages 1355-1364.
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Fang Yong, Ni Xudong & Tan Lijie. (2013) Human papillomavirus types 16 and 18 in esophagus squamous cell carcinoma: a meta-analysis. Annals of Epidemiology 23:11, pages 726-734.
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