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Pharmaceutical Development and Technology Volume 18, 2013 - Issue 6
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Research Article

Solubilization of entecavir by povidone to overcome content uniformity challenges for low-dose tablet formulations

Divyakant DesaiDrug Product Science and Technology, New Brunswick, NJ, USACorrespondence[email protected]
,
Danping LiDrug Product Science and Technology, New Brunswick, NJ, USA
,
Abizer HarianawalaDrug Product Science and Technology, New Brunswick, NJ, USA
,
Omar SprockelDrug Product Science and Technology, New Brunswick, NJ, USA
,
Ming HuangAnalytical and Bioanalytical Development, Bristol-Myers Squibb Co., New Brunswick, NJ, USA
&
Peter TimminsDrug Product Science and Technology, Bristol-Myers Squibb, Moreton, Merseyside, UK
Pages 1305-1313 | Received 06 Feb 2012, Accepted 23 Feb 2012, Published online: 03 Apr 2012

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Michael Leane, Kendal Pitt & Gavin Reynolds. (2015) A proposal for a drug product Manufacturing Classification System (MCS) for oral solid dosage forms. Pharmaceutical Development and Technology 20:1, pages 12-21.
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Susanne Page & Anikó Szepes. 2021. Solid State Development and Processing of Pharmaceutical Molecules. Solid State Development and Processing of Pharmaceutical Molecules 325 364 .
Xi-Chuan Wei, Bo Cao, Chuan-Hong Luo, Hao-Zhou Huang, Peng Tan, Xiao-Rong Xu, Run-Chun Xu, Ming Yang, Yi Zhang, Li Han & Ding-Kun Zhang. (2020) Recent advances of novel technologies for quality consistency assessment of natural herbal medicines and preparations. Chinese Medicine 15:1.
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Andrew T. Francis, Tai T. Nguyen, Matthew S. Lamm, Ryan Teller, Seth P. Forster, Wei Xu, Timothy Rhodes, Ronald L. Smith, Jesse Kuiper, Yongchao Su & Dan Fu. (2018) In Situ Stimulated Raman Scattering (SRS) Microscopy Study of the Dissolution of Sustained-Release Implant Formulation. Molecular Pharmaceutics 15:12, pages 5793-5801.
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Yanlei Kang, Zhanying Shao, Qiang Wang, Xiurong Hu & Dongdong Yu. (2018) Quantitation of polymorphic impurity in entecavir polymorphic mixtures using powder X-ray diffractometry and Raman spectroscopy. Journal of Pharmaceutical and Biomedical Analysis 158, pages 28-37.
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Zhe Li, LiJie Zhao, Xiao Lin, Lan Shen & Yi Feng. (2017) Direct compaction: An update of materials, trouble-shooting, and application. International Journal of Pharmaceutics 529:1-2, pages 543-556.
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Martin Kuentz, René Holm & David P. Elder. (2016) Methodology of oral formulation selection in the pharmaceutical industry. European Journal of Pharmaceutical Sciences 87, pages 136-163.
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Jong-Lae Lim, Min-Hyo Ki, Min Kyung Joo, Sung-Won An, Kyu-Mok Hwang & Eun-Seok Park. (2015) An injectable liquid crystal system for sustained delivery of entecavir. International Journal of Pharmaceutics 490:1-2, pages 265-272.
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Andrew Hill, Dzintars Gotham, Graham Cooke, Sanjay Bhagani, Isabelle Andrieux-Meyer, Jennifer Cohn & Joseph Fortunak. (2015) Analysis of minimum target prices for production of entecavir to treat hepatitis B in high- and low-income countries. Journal of Virus Eradication 1:2, pages 103-110.
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Abid Mehmood Yousaf, Jun-Pil Jee, Seung Rim Hwang, Han-Joo Maeng, Young-Joon Park, Jong Oh Kim, Chul Soon Yong, Han-Gon Choi & Kwan Hyung Cho. (2014) Development of direct compression entecavir 0.5 mg-loaded tablet exhibiting enhanced content uniformity. Powder Technology 267, pages 302-308.
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