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Volume 18, Issue 6

Pharmaceutical Development and Technology

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Pharmaceutical Development and Technology, Volume 18, Issue 6 (2013)

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Pharmaceutical Development and Technology, Volume 18, Issue 6 (2013)

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Review: Pharmaceutical Development Fundamentals

Review Article

Formulation design, challenges, and development considerations for fixed dose combination (FDC) of oral solid dosage forms

Divyakant Desai, Jennifer Wang, Hong Wen, Xuhong Li & Peter Timmins

Pages: 1265-1276

Published online: 16 Feb 2012

AbstractforFormulation design, challenges, and development considerations for fixed dose combination (FDC) of oral solid dosage forms | Full Text | References | PDF (796.6 KB)

3456 Views
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Research Article

Article

Content uniformity testing: suitability of different approaches for marketed low dose tablets

Magdi M. Abdel Hamid, Mohamed A. Elnabrawi, Fars K. Alanazi, Magdy I. Mohamed & Adel A. Sakr

Pages: 1277-1287

Published online: 13 Feb 2012

AbstractforContent uniformity testing: suitability of different approaches for marketed low dose tablets | Full Text | References | PDF (1.3 MB)

264 Views
1 CrossRef citations
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Article

Permeability and toxicity characteristics of L-cysteine and 2-methyl-thiazolidine-4-carboxylic acid in Caco-2 cells

Alma Kartal-Hodzic, Tuuli Marvola, Mechthild Schmitt, Kirsi Harju, Marikki Peltoniemi & Mia Sivén

Pages: 1288-1293

Published online: 22 Feb 2012

AbstractforPermeability and toxicity characteristics of L-cysteine and 2-methyl-thiazolidine-4-carboxylic acid in Caco-2 cells | Full Text | References | PDF (768.9 KB)

231 Views
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Article

Self nano-emulsifying simvastatin based tablets: design and in vitro/in vivo evaluation

Ghada Abdelbary, Maha Amin & Salwa Salah

Pages: 1294-1304

Published online: 03 Apr 2012

AbstractforSelf nano-emulsifying simvastatin based tablets: design and in vitro/in vivo evaluation | Full Text | References | PDF (825 KB)

285 Views
21 CrossRef citations
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Article

Solubilization of entecavir by povidone to overcome content uniformity challenges for low-dose tablet formulations

Divyakant Desai, Danping Li, Abizer Harianawala, Omar Sprockel, Ming Huang & Peter Timmins

Pages: 1305-1313

Published online: 03 Apr 2012

AbstractforSolubilization of entecavir by povidone to overcome content uniformity challenges for low-dose tablet formulations | Full Text | References | PDF (1 MB)

361 Views
10 CrossRef citations
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Article

Reformulation of Stmerin^® D CFC formulation using HFA propellants

Saburo Murata, Takashi Izumi & Hideki Ito

Pages: 1314-1318

Published online: 21 Apr 2012

AbstractforReformulation of Stmerin^® D CFC formulation using HFA propellants | Full Text | References | PDF (718.1 KB)

88 Views
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Article

Factors affecting solubilization of a poorly soluble novel tubulin-binding agent

Amit K. Shah Ph.D. & Christy M. Wyandt Ph.D.

Pages: 1319-1328

Published online: 28 May 2012

AbstractforFactors affecting solubilization of a poorly soluble novel tubulin-binding agent | Full Text | References | PDF (831.4 KB)

120 Views
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Article

Pharmaceutical evaluation and dynamic vapor sorption studies of fast dissolving intraoral films of Loratadine

Arun Arya, Vijay Sharma & Kamla Pathak

Pages: 1329-1338

Published online: 05 Jun 2012

AbstractforPharmaceutical evaluation and dynamic vapor sorption studies of fast dissolving intraoral films of Loratadine | Full Text | References | PDF (958.3 KB)

448 Views
17 CrossRef citations
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Article

Penetration enhancer-containing vesicles (PEVs) as carriers for cutaneous delivery of minoxidil: in vitro evaluation of drug permeation by infrared spectroscopy

Simona Mura, Maria Manconi, Anna Maria Fadda, Maria Chiara Sala, Jacopo Perricci, Elena Pini & Chiara Sinico

Pages: 1339-1345

Published online: 08 May 2012

AbstractforPenetration enhancer-containing vesicles (PEVs) as carriers for cutaneous delivery of minoxidil: in vitro evaluation of drug permeation by infrared spectroscopy | Full Text | References | PDF (1.1 MB)

294 Views
28 CrossRef citations
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Article

Ketoconazole ion-exchange fiber complex: a novel method to reduce the individual difference of bioavailability in oral administration caused by gastric anacidity

Che Xin, Wang Li-hong, Yuan Jing, Yang Yang, Yuan Yue, Wang Qi-fang & Li San-ming

Pages: 1346-1354

Published online: 07 Jun 2012

AbstractforKetoconazole ion-exchange fiber complex: a novel method to reduce the individual difference of bioavailability in oral administration caused by gastric anacidity | Full Text | References | PDF (1 MB)

105 Views
6 CrossRef citations
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Article

“Real-time” disintegration analysis and D-optimal experimental design for the optimization of diclofenac sodium fast-dissolving films

Yasser El-Malah & Sami Nazzal

Pages: 1355-1360

Published online: 11 Jul 2012

Abstractfor“Real-time” disintegration analysis and D-optimal experimental design for the optimization of diclofenac sodium fast-dissolving films | Full Text | References | PDF (906.5 KB)

220 Views
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Article

Aerosol-based efficient delivery of azithromycin to alveolar macrophages for treatment of respiratory infections

Kohei Togami, Sumio Chono & Kazuhiro Morimoto

Pages: 1361-1365

Published online: 20 Jul 2012

AbstractforAerosol-based efficient delivery of azithromycin to alveolar macrophages for treatment of respiratory infections | Full Text | References | PDF (632.3 KB)

221 Views
5 CrossRef citations
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Article

Evaluation of a sieve classification method for characterization of low-dose interactive mixtures

Susanne Bredenberg, Anna Dahlgren & Sofia Mattsson

Pages: 1366-1371

Published online: 24 Sep 2012

AbstractforEvaluation of a sieve classification method for characterization of low-dose interactive mixtures | Full Text | References | PDF (827.1 KB)

148 Views
2 CrossRef citations
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Article

Zero-order release profile of metoclopramide hydrochloride sublingual tablet formulation

Randa Latif

Pages: 1372-1378

Published online: 10 Sep 2012

AbstractforZero-order release profile of metoclopramide hydrochloride sublingual tablet formulation | Full Text | References | PDF (893 KB)

135 Views
3 CrossRef citations
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Article

In situ lyophilisation of nifedipine directly in hard gelatine capsules

Matthew Crum, Amal Ali Elkordy, Moataz Zarara & Eman Ali Elkordy

Pages: 1379-1390

Published online: 20 Sep 2012

AbstractforIn situ lyophilisation of nifedipine directly in hard gelatine capsules | Full Text | References | PDF (2.6 MB)

148 Views
4 CrossRef citations
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Article

Applying response surface methodology to optimize nimesulide permeation from topical formulation

Yasser Shahzad, Urooj Afreen, Syed Nisar Hussain Shah & Talib Hussain

Pages: 1391-1398

Published online: 20 Sep 2012

AbstractforApplying response surface methodology to optimize nimesulide permeation from topical formulation | Full Text | References | PDF (962.9 KB)

111 Views
16 CrossRef citations
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Article

In vitro dissolution of pH sensitive microparticles for colon-specific drug delivery

Anna Angela Barba, Annalisa Dalmoro, Matteo d’Amore & Gaetano Lamberti

Pages: 1399-1406

Published online: 15 Oct 2012

AbstractforIn vitro dissolution of pH sensitive microparticles for colon-specific drug delivery | Full Text | References | PDF (709.6 KB)

171 Views
15 CrossRef citations
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Article

Real-time dissolution behavior of furosemide in biorelevant media as determined by UV imaging

Sarah Gordon, Kaisa Naelapää, Jukka Rantanen, Arzu Selen, Anette Müllertz & Jesper Østergaard

Pages: 1407-1416

Published online: 09 Nov 2012

AbstractforReal-time dissolution behavior of furosemide in biorelevant media as determined by UV imaging | Full Text | References | PDF (933.1 KB)

439 Views
25 CrossRef citations
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Article

Investigation of different emulsion systems for dermal delivery of nicotinamide

Sakine Tuncay & Özgen Özer

Pages: 1417-1423

Published online: 06 Jun 2013

AbstractforInvestigation of different emulsion systems for dermal delivery of nicotinamide | Full Text | References | PDF (710.2 KB)

407 Views
11 CrossRef citations
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Article

Development of water-in-oil microemulsions with the potential of prolonged release for oral delivery of L-glutathione

Jingyuan Wen, Yun Du, Danhui Li & Raid Alany

Pages: 1424-1429

Published online: 06 Jun 2013

AbstractforDevelopment of water-in-oil microemulsions with the potential of prolonged release for oral delivery of L-glutathione | Full Text | References | PDF (1.3 MB)

223 Views
13 CrossRef citations
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Pharmaceutical Development and Technology (Vol.18, Iss.6, 2013)

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