Advanced search
Publication Cover
The Aging Male Volume 16, 2013 - Issue 2
Submit an article Journal homepage
1,209
Views
31
CrossRef citations to date
0
Altmetric
Research Article

Effects of oral testosterone undecanoate therapy on bone mineral density and body composition in 322 aging men with symptomatic testosterone deficiency: a 1-year, randomized, placebo-controlled, dose-ranging study

Pierre M. G. BoulouxCentre for Neuroendocrinology, Royal Free and University College School of Medicine LondonUKCorrespondence[email protected]
,
Jean-Jacques LegrosDepartment of Endocrinology, University of Liege LiegeBelgium
,
Jolanda M. H. ElbersGlobal Clinical Research, Merck Sharp & Dohme Corp. OssThe Netherlands
,
T. B. Paul GeurtsGlobal Communications, MSD Animal Health BoxmeerThe Netherlands
,
Marion J. G. H. KaspersGlobal Research Data and Quantitative Sciences, Merck Sharp & Dohme OssThe Netherlands
,
Alan G. MeehanOffice of the Chief Medical Officer, Merck Sharp & Dohme Corp. Whitehouse Station, NJUSA
,
Eric J. H. MeulemanDepartment of Urology, Free University Medical Center AmsterdamThe Netherlands
& and for the Study 43203 Investigators show all
Pages 38-47 | Received 05 Sep 2012, Accepted 02 Feb 2013, Published online: 12 Apr 2013

Citations (31)

Keep up to date with the latest research on this topic with citation updates for this article.

Subscribe to citation updates

Read on this site (4)

Adam J. Rose, Susan L. Greenspan & Guneet K. Jasuja. (2023) Gaps in evidence on treatment of male osteoporosis: a Research Agenda. The Aging Male 26:1.
Read now
Marta Martín-Fernández, Francisco-Miguel Garzón-Márquez, Manuel Díaz-Curiel, Iván Prieto-Potin, Luis Alvarez-Galovich, David Guede, Jose Ramón Caeiro-Rey & Concepción De la Piedra. (2020) Comparative study of the effects of osteoprotegerin and testosterone on bone quality in male orchidectomised rats. The Aging Male 23:3, pages 189-201.
Read now
Steven A. Kaplan, Jeannette Y. Lee, Edward A. O’Neill, Alan G. Meehan & John W. Kusek. (2013) Prevalence of low testosterone and its relationship to body mass index in older men with lower urinary tract symptoms associated with benign prostatic hyperplasia. The Aging Male 16:4, pages 169-172.
Read now
Josep Rodriguez-Tolrà, Josep Torremadé Barreda, Luis del Rio, Silvana di Gregorio & Eladio Franco Miranda. (2013) Effects of testosterone treatment on body composition in males with testosterone deficiency syndrome. The Aging Male 16:4, pages 184-190.
Read now

Articles from other publishers (27)

Pedro Iglesias, Alberto Núñez & Juan J. Díez. 2023. Testosterone. Testosterone 193 229 .
Svetlana Kalinchenko, Igor Tyuzikov, George Mskhalaya & Yulia Tishova. 2023. Testosterone. Testosterone 281 301 .
Karel David, Nick Narinx, Leen Antonio, Pieter Evenepoel, Frank Claessens, Brigitte Decallonne & Dirk Vanderschueren. (2022) Bone health in ageing men. Reviews in Endocrine and Metabolic Disorders 23:6, pages 1173-1208.
Crossref
Leonardo Bandeira, Barbara C. Silva & John P. Bilezikian. (2022) Male osteoporosis. Archives of Endocrinology and Metabolism 66:5, pages 739-747.
Crossref
Syed W Ahmad, Gianfranco Molfetto, David Montoya & Ariday Camero. (2022) Is Oral Testosterone the New Frontier of Testosterone Replacement Therapy?. Cureus.
Crossref
G. Corona, W. Vena, A. Pizzocaro, V. A. Giagulli, D. Francomano, G. Rastrelli, G. Mazziotti, A. Aversa, A. M. Isidori, R. Pivonello, L. Vignozzi, E. Mannucci, M. Maggi & A. Ferlin. (2022) Testosterone supplementation and bone parameters: a systematic review and meta-analysis study. Journal of Endocrinological Investigation 45:5, pages 911-926.
Crossref
Biagio Barone, Luigi Napolitano, Marco Abate, Luigi Cirillo, Pasquale Reccia, Francesco Passaro, Carmine Turco, Simone Morra, Francesco Mastrangelo, Antonio Scarpato, Ugo Amicuzi, Vincenzo Morgera, Lorenzo Romano, Francesco Paolo Calace, Savio Domenico Pandolfo, Luigi De Luca, Achille Aveta, Enrico Sicignano, Massimiliano Trivellato, Gianluca Spena, Carlo D’Alterio, Giovanni Maria Fusco, Raffaele Vitale, Davide Arcaniolo & Felice Crocetto. (2022) The Role of Testosterone in the Elderly: What Do We Know?. International Journal of Molecular Sciences 23:7, pages 3535.
Crossref
Prachi Singh, Naima Covassin, Kara Marlatt, Kishore M. Gadde & Steven B. Heymsfield. 2011. Comprehensive Physiology. Comprehensive Physiology 2949 2993 .
Giacomo Garibotto, Pasquale Esposito, Daniela Picciotto & Daniela Verzola. (2021) Testosterone Disorders and Male Hypogonadism in Kidney Disease. Seminars in Nephrology 41:2, pages 114-125.
Crossref
Kazuyoshi Shigehara, Kouji Izumi, Yoshifumi Kadono & Atsushi Mizokami. (2021) Testosterone and Bone Health in Men: A Narrative Review. Journal of Clinical Medicine 10:3, pages 530.
Crossref
Vincenzo Rochira. (2020) Late‐onset Hypogonadism: Bone health. Andrology 8:6, pages 1539-1550.
Crossref
Abdulmaged M. Traish & Abraham Morgentaler. 2019. Sex Differences in Cardiovascular Physiology and Pathophysiology. Sex Differences in Cardiovascular Physiology and Pathophysiology 321 354 .
André Tchernof, Dannick Brochu, Ina Maltais‐Payette, Mohamed Fouad Mansour, Geneviève B. Marchand, Anne‐Marie Carreau & Jordanna Kapeluto. 2011. Comprehensive Physiology. Comprehensive Physiology 1253 1290 .
Dong-Eun Shin, Tae-Keun Ahn, Jee-Woong Kim, Chi-Hoon Oh & SeongJu Choi. (2018) Testosterone and Male Osteoporosis. Clinical Reviews in Bone and Mineral Metabolism 16:2, pages 49-56.
Crossref
Gary Golds, Devon Houdek & Terra Arnason. (2017) Male Hypogonadism and Osteoporosis: The Effects, Clinical Consequences, and Treatment of Testosterone Deficiency in Bone Health. International Journal of Endocrinology 2017, pages 1-15.
Crossref
Svetlana Kalinchenko, Igor Tyuzikov, George Mskhalaya & Yulia Tishova. 2017. Testosterone. Testosterone 203 224 .
Marie Sinclair, Mathis Grossmann, Rudolf Hoermann, Peter W. Angus & Paul J. Gow. (2016) Testosterone therapy increases muscle mass in men with cirrhosis and low testosterone: A randomised controlled trial. Journal of Hepatology 65:5, pages 906-913.
Crossref
Abdulmaged M. Traish. (2016) Testosterone therapy in men with testosterone deficiency: are the benefits and cardiovascular risks real or imagined?. American Journal of Physiology-Regulatory, Integrative and Comparative Physiology 311:3, pages R566-R573.
Crossref
Giovanni Corona, Vito A Giagulli, Elisa Maseroli, Linda Vignozzi, Antonio Aversa, Michael Zitzmann, Farid Saad, Edoardo Mannucci & Mario Maggi. (2016) THERAPY OF ENDOCRINE DISEASE: Testosterone supplementation and body composition: results from a meta-analysis study. European Journal of Endocrinology 174:3, pages R99-R116.
Crossref
F. Comhaire & A. Mahmoud. (2016) The andrologist's contribution to a better life for ageing men: part 1. Andrologia 48:1, pages 87-98.
Crossref
F Saad, A Yassin, G Doros & A Haider. (2015) Effects of long-term treatment with testosterone on weight and waist size in 411 hypogonadal men with obesity classes I-III: observational data from two registry studies. International Journal of Obesity 40:1, pages 162-170.
Crossref
D. M. Kelly & T. H. Jones. (2015) Testosterone and obesity. Obesity Reviews 16:7, pages 581-606.
Crossref
Dirk VanderschuerenMichaël R. LaurentFrank ClaessensEvelien GielenMarie K. Lagerquist, Liesbeth Vandenput, Anna E. Börjesson & Claes Ohlsson. (2014) Sex Steroid Actions in Male Bone. Endocrine Reviews 35:6, pages 906-960.
Crossref
Michael S. Irwig. (2014) Bone health in hypogonadal men. Current Opinion in Urology 24:6, pages 608-613.
Crossref
Abdulmaged M. Traish. (2014) Testosterone and weight loss. Current Opinion in Endocrinology, Diabetes & Obesity 21:5, pages 313-322.
Crossref
Abdulmaged M. Traish. (2014) Adverse health effects of testosterone deficiency (TD) in men. Steroids 88, pages 106-116.
Crossref
Ryan P. Smith, Abhinav Khanna, Robert M. Coward, Saneal Rajanahally, Jason R. Kovac, Marshall A. Gonzales & Larry I. Lipshultz. (2013) Factors Influencing Patient Decisions to Initiate and Discontinue Subcutaneous Testosterone Pellets (Testopel) for Treatment of Hypogonadism. The Journal of Sexual Medicine 10:9, pages 2326-2333.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.