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Research Article

The non-mammalian host Galleria mellonella can be used to study the virulence of the fungal pathogen Candida tropicalis and the efficacy of antifungal drugs during infection by this pathogenic yeast

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Pages 461-472 | Received 26 Apr 2012, Accepted 29 Sep 2012, Published online: 21 Nov 2012

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Zhiya Yang, Fangfang Zhang, Dongmei Li, Sisi Wang, Zhiping Pang, Liu Chen, Renzhe Li & Dongmei Shi. (2022) Correlation Between Drug Resistance and Virulence of Candida Isolates from Patients with Candidiasis. Infection and Drug Resistance 15, pages 7459-7473.
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Ainara Hernando-Ortiz, Estibaliz Mateo, Aitzol Perez-Rodriguez, Piet W.J. de Groot, Guillermo Quindós & Elena Eraso. (2021) Virulence of Candida auris from different clinical origins in Caenorhabditis elegans and Galleria mellonella host models. Virulence 12:1, pages 1063-1075.
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Nancy E Lozoya-Pérez, Laura C García-Carnero, José A Martínez-Álvarez, Iván Martínez-Duncker & Héctor M Mora-Montes. (2021) Tenebrio molitor as an Alternative Model to Analyze the Sporothrix Species Virulence. Infection and Drug Resistance 14, pages 2059-2072.
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Rodnei Dennis Rossoni, Patrícia Pimentel de Barros, Lucas Alexandre das Chagas Lopes, Felipe Camargo Ribeiro, Toshiyuki Nakatsuka, Hideto Kasaba & Juliana Campos Junqueira. (2019) Effects of surface pre-reacted glass-ionomer (S-PRG) eluate on Candida spp.: antifungal activity, anti-biofilm properties, and protective effects on Galleria mellonella against C. albicans infection. Biofouling 35:9, pages 997-1006.
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Adeline L. Jorjão, Luciane D. Oliveira, Liliana Scorzoni, Lívia Mara A. Figueiredo-Godoi, Marcia Cristina A. Prata, Antonio Olavo C. Jorge & Juliana C. Junqueira. (2018) From moths to caterpillars: Ideal conditions for Galleria mellonella rearing for in vivo microbiological studies. Virulence 9:1, pages 383-389.
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Lauren Ames, Sarah Duxbury, Bogna Pawlowska, Hsueh-lui Ho, Ken Haynes & Steven Bates. (2017) Galleria mellonella as a host model to study Candida glabrata virulence and antifungal efficacy. Virulence 8:8, pages 1909-1917.
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Olivia L. Champion, Sariqa Wagley & Richard W. Titball. (2016) Galleria mellonella as a model host for microbiological and toxin research. Virulence 7:7, pages 840-845.
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Alane T.-P. Moralez, Hugo F. Perini, Luciana Furlaneto-Maia, Ricardo S. Almeida, Luciano A. Panagio & Marcia C. Furlaneto. (2016) Phenotypic switching of Candida tropicalis is associated with cell damage in epithelial cells and virulence in Galleria mellonella model. Virulence 7:4, pages 379-386.
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Caroline Maria Marcos, Julhiany de Fátima da Silva, Haroldo Cesar de Oliveira, Patrícia Akemi Assato, Junya de Lacorte Singulani, Angela Maria Lopez, Diana Patricia Tamayo, Orville Hernandez-Ruiz, Juan G McEwen, Maria José Soares Mendes-Giannini & Ana Marisa Fusco-Almeida. (2016) Decreased expression of 14-3-3 in Paracoccidioides brasiliensis confirms its involvement in fungal pathogenesis . Virulence 7:2, pages 72-84.
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Liliana Scorzoni, Ana Carolina Alves de Paula e Silva, Junya de Lacorte Singulani, Fernanda Sangalli Leite, Haroldo Cesar de Oliveira, Rosangela Aparecida Moraes da Silva, Ana Marisa Fusco-Almeida & Maria José Soares Mendes-Giannini. (2015) Comparison of virulence between Paracoccidioides brasiliensis and Paracoccidioides lutzii using Galleria mellonella as a host model. Virulence 6:8, pages 766-776.
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L Alcazar-Fuoli, Mj Buitrago, A Gomez-Lopez & E Mellado. (2015) An alternative host model of a mixed fungal infection by azole susceptible and resistant Aspergillus spp strains. Virulence 6:4, pages 376-384.
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Nuria Trevijano-Contador, Inés Herrero-Fernández, Irene García-Barbazán, Liliana Scorzoni, Cristina Rueda, Suélen Andreia Rossi, Rocío García-Rodas & Oscar Zaragoza. (2015) Cryptococcus neoformans induces antimicrobial responses and behaves as a facultative intracellular pathogen in the non mammalian model Galleria mellonella. Virulence 6:1, pages 66-74.
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Ilse D Jacobsen. (2014) Galleria mellonella as a model host to study virulence of Candida. Virulence 5:2, pages 237-239.
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Edina K Szabo & Donna M MacCallum. (2014) A novel renal epithelial cell in vitro assay to assess Candida albicans virulence. Virulence 5:2, pages 286-296.
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Sara Gago, Rocío García-Rodas, Isabel Cuesta, Emilia Mellado & Ana Alastruey-Izquierdo. (2014) Candida parapsilosis, Candida orthopsilosis, and Candida metapsilosis virulence in the non-conventional host Galleria mellonella. Virulence 5:2, pages 278-285.
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