Citations (86)
Keep up to date with the latest research on this topic with citation updates for this article.
Read on this site (18)
Beilei Bi, Yi Jiang, Yin Shi & Fan Ruan. (2022) Bazedoxifene plus conjugated estrogens improve menopausal symptoms in postmenopausal women: a systematic review and meta-analysis. Gynecological Endocrinology 38:10, pages 813-821.
Read now
Read now
Risa Kagan, Paula Abreu & Emma Andrews. (2018) Vaginal bleeding/spotting with conjugated estrogens/bazedoxifene, conjugated estrogens/medroxyprogesterone acetate, and placebo. Postgraduate Medicine 130:8, pages 687-693.
Read now
Read now
Placido Llaneza, Joaquim Calaf, Ana Rosa Jurado, Nicolas Mendoza, Borja Otero, Francisco Quereda, Rafael Sánchez-Borrego & Daniel Lubian. (2018) What do TSECs provide in the menopausal hormone therapy?. Gynecological Endocrinology 34:10, pages 826-832.
Read now
Read now
Melanie K. Miller, Joshua R. Smith, Jacqueline J. Norman & Anita H. Clayton. (2018) Expert opinion on existing and developing drugs to treat female sexual dysfunction. Expert Opinion on Emerging Drugs 23:3, pages 223-230.
Read now
Read now
Sharon J. Parish & John A. Gillespie. (2017) The evolving role of oral hormonal therapies and review of conjugated estrogens/bazedoxifene for the management of menopausal symptoms. Postgraduate Medicine 129:3, pages 340-351.
Read now
Read now
Risa Kagan, Steven R Goldstein, James H Pickar & Barry S Komm. (2016) Patient considerations in the management of menopausal symptoms: role of conjugated estrogens with bazedoxifene. Therapeutics and Clinical Risk Management 12, pages 549-562.
Read now
Read now
B. S. Komm, J. R. Thompson & S. Mirkin. (2015) Cardiovascular safety of conjugated estrogens plus bazedoxifene: meta-analysis of the SMART trials. Climacteric 18:4, pages 503-511.
Read now
Read now
Andrea R Genazzani, Barry S Komm & James H Pickar. (2015) Emerging hormonal treatments for menopausal symptoms. Expert Opinion on Emerging Drugs 20:1, pages 31-46.
Read now
Read now
Maryam Sharifi & E Michael Lewiecki. (2014) Conjugated estrogens combined with bazedoxifene: the first approved tissue selective estrogen complex therapy. Expert Review of Clinical Pharmacology 7:3, pages 281-291.
Read now
Read now
Lin H Soe, Gregory T Wurz, Chiao-Jung Kao & Michael W DeGregorio. (2013) Ospemifene for the treatment of dyspareunia associated with vulvar and vaginal atrophy: potential benefits in bone and breast. International Journal of Women's Health 5, pages 605-611.
Read now
Read now
J. V. Pinkerton, B. S. Komm & S. Mirkin. (2013) Tissue selective estrogen complex combinations with bazedoxifene/conjugated estrogens as a model. Climacteric 16:6, pages 618-628.
Read now
Read now
Maurizio Rossini, Stefano Lello, Ignazio Sblendorio, Ombretta Viapiana, Elena Fracassi, Silvano Adami & Davide Gatti. (2013) Profile of bazedoxifene/conjugated estrogens for the treatment of estrogen deficiency symptoms and osteoporosis in women at risk of fracture. Drug Design, Development and Therapy 7, pages 601-610.
Read now
Read now
S. Mirkin, B. S. Komm, K. Pan & A. A. Chines. (2013) Effects of bazedoxifene/conjugated estrogens on endometrial safety and bone in postmenopausal women. Climacteric 16:3, pages 338-346.
Read now
Read now
H. Yu, J. Racketa, A. A. Chines & S. Mirkin. (2013) Hot flush symptom-free days with bazedoxifene/conjugated estrogens in postmenopausal women. Climacteric 16:2, pages 252-257.
Read now
Read now
Barry S Komm & Sebastian Mirkin. (2012) Incorporating bazedoxifene/conjugated estrogens into the current paradigm of menopausal therapy. International Journal of Women's Health 4, pages 129-140.
Read now
Read now
J. V. Pinkerton, J. H. Pickar, J. Racketa & S. Mirkin. (2012) Bazedoxifene/conjugated estrogens for menopausal symptom treatment and osteoporosis prevention. Climacteric 15:5, pages 411-418.
Read now
Read now
Rebekah Burich & Michael DeGregorio. (2011) Current treatment options for vulvovaginal atrophy. Expert Review of Obstetrics & Gynecology 6:2, pages 141-151.
Read now
Read now
Susan R Davis & Fiona Jane. (2010) Drugs for the treatment of menopausal symptoms. Expert Opinion on Pharmacotherapy 11:8, pages 1329-1341.
Read now
Read now
Articles from other publishers (68)
Lucia A Lara, Denisse Cartagena-Ramos, Jaqueline BP Figueiredo, Ana Carolina JS Rosa-e-Silva, Rui A Ferriani, Wellington P Martins & Miguel Fuentealba-Torres. (2023) Hormone therapy for sexual function in perimenopausal and postmenopausal women. Cochrane Database of Systematic Reviews 2023:8.
Crossref
Crossref
Nadia Meziou, Clare Scholfield, Caroline A. Taylor & Heather L. Armstrong. (2023) Hormone therapy for sexual function in perimenopausal and postmenopausal women: a systematic review and meta-analysis update. Menopause 30:6, pages 659-671.
Crossref
Crossref
Lucia Merlino, Giulia D’Ovidio, Viviana Matys, Maria Grazia Piccioni, Maria Grazia Porpora, Roberto Senatori, Maria Federica Viscardi, Antonio Vitale & Carlo Della Rocca. (2023) Therapeutic Choices for Genitourinary Syndrome of Menopause (GSM) in Breast Cancer Survivors: A Systematic Review and Update. Pharmaceuticals 16:4, pages 550.
Crossref
Crossref
. (2022) The 2022 hormone therapy position statement of The North American Menopause Society. Menopause 29:7, pages 767-794.
Crossref
Crossref
Erum Zafar, Muhammad Faisal Maqbool, Asia Iqbal, Amara Maryam, Hafiz Abdullah Shakir, Muhammad Irfan, Muhammad Khan, Yongming Li & Tonghui Ma. (2021) A comprehensive review on anticancer mechanism of bazedoxifene. Biotechnology and Applied Biochemistry 69:2, pages 767-782.
Crossref
Crossref
Daniel María Lubián López. (2022) Management of genitourinary syndrome of menopause in breast cancer survivors: An update. World Journal of Clinical Oncology 13:2, pages 71-100.
Crossref
Crossref
Saikat Mitra, Mashia Subha Lami, Avoy Ghosh, Rajib Das, Trina Ekawati Tallei, Fatimawali, Fahadul Islam, Kuldeep Dhama, M. Yasmin Begum, Afaf Aldahish, Kumarappan Chidambaram & Talha Bin Emran. (2022) Hormonal Therapy for Gynecological Cancers: How Far Has Science Progressed toward Clinical Applications?. Cancers 14:3, pages 759.
Crossref
Crossref
Hesham Y Elnazer & David S Baldwin. (2020) Structured review of the use of the Arizona sexual experiences scale in clinical settings. Human Psychopharmacology: Clinical and Experimental 35:3.
Crossref
Crossref
Risa Kagan, Susan Kellogg-Spadt & Sharon J. Parish. (2019) Practical Treatment Considerations in the Management of Genitourinary Syndrome of Menopause. Drugs & Aging 36:10, pages 897-908.
Crossref
Crossref
Paola Villa, Inbal Dona Amar, Maayan Shachor, Clelia Cipolla, Fabio Ingravalle & Giovanni Scambia. (2019) Cardiovascular Risk/Benefit Profile of MHT. Medicina 55:9, pages 571.
Crossref
Crossref
Meghan S Perkins, Renate Louw-du Toit & Donita Africander. (2018) Hormone therapy and breast cancer: emerging steroid receptor mechanisms. Journal of Molecular Endocrinology 61:4, pages R133-R160.
Crossref
Crossref
. (2018) The 2017 hormone therapy position statement of The North American Menopause Society. Menopause 25:11, pages 1362-1387.
Crossref
Crossref
Susan J. Diem, Katherine A. Guthrie, Caroline M. Mitchell, Susan D. Reed, Joseph C. Larson, Kristine E. Ensrud & Andrea Z. LaCroix. (2018) Effects of vaginal estradiol tablets and moisturizer on menopause-specific quality of life and mood in healthy postmenopausal women with vaginal symptoms: a randomized clinical trial. Menopause 25:10, pages 1086-1093.
Crossref
Crossref
James H. Pickar, Matthieu Boucher & Diana Morgenstern. (2018) Tissue selective estrogen complex (TSEC): a review. Menopause 25:9, pages 1033-1045.
Crossref
Crossref
James H. Pickar, Joanne LavenbergKaijie PanBarry S. Komm. (2018) Initial investigation into the optimal dose ratio of conjugated estrogens and bazedoxifene: a double-blind, randomized, placebo-controlled phase 2 dose-finding study. Menopause 25:3, pages 273-285.
Crossref
Crossref
Kathryn I. Marko & James A. Simon. (2018) Clinical trials in menopause. Menopause 25:2, pages 217-230.
Crossref
Crossref
. (2017) The 2017 hormone therapy position statement of The North American Menopause Society. Menopause 24:7, pages 728-753.
Crossref
Crossref
Sung Wook Chun. (2017) An Overview of the Clinical Efficacy and Safety of Tissue Selective Estrogen Complex: From the Selective Estrogens, Menopause, and Response to Therapy (SMART) Trials. Kosin Medical Journal 32:1, pages 5-16.
Crossref
Crossref
JoAnn V. Pinkerton, Andrew G. Bushmakin, Barry S. Komm & Lucy Abraham. (2017) Relationship between changes in vulvar-vaginal atrophy and changes in sexual functioning. Maturitas 100, pages 57-63.
Crossref
Crossref
. (2017) Bazedoxifene for HRT?. Drug and Therapeutics Bulletin 55:4, pages 42-44.
Crossref
Crossref
Nooshin YoshanyMohammad Ali MorowatisharifabadHamideh MihanpourNarjes BahriKhair Mohammad Jadgal. (2017) The Effect of Husbands' Education Regarding Menopausal Health on Marital Satisfaction of Their Wives. Journal of Menopausal Medicine 23:1, pages 15.
Crossref
Crossref
Santiago Palacios & Mariella Lilue. 2017. Menopause. Menopause
197
212
.
Alessandra Graziottin & Filippo MurinaAlessandra Graziottin & Filippo Murina. 2017. Vulvar Pain. Vulvar Pain
129
148
.
Alessandra Graziottin & Filippo MurinaAlessandra Graziottin & Filippo Murina. 2017. Vulvar Pain. Vulvar Pain
191
232
.
Lucy Abraham, Andrew G. Bushmakin, Erika Dragon, Barry S. Komm & JoAnn V. Pinkerton. (2016) Direct and indirect effects of conjugated estrogens/bazedoxifene treatment on quality of life in postmenopausal women. Maturitas 94, pages 173-179.
Crossref
Crossref
Risa Kagan, Barry S. Komm, Kelly A. Ryan, Joanne Lavenberg, Ching-Ray Yu & JoAnn V. Pinkerton. (2016) Timing and persistence of effect of conjugated estrogens/bazedoxifene in postmenopausal women. Menopause 23:11, pages 1204-1213.
Crossref
Crossref
David F. ArcherEllen W. FreemanBarry S. KommKelly A. RyanChing-Ray YuSebastian MirkinJoAnn V. Pinkerton. (2016) Pooled Analysis of the Effects of Conjugated Estrogens/Bazedoxifene on Vasomotor Symptoms in the Selective Estrogens, Menopause, and Response to Therapy Trials. Journal of Women's Health 25:11, pages 1102-1111.
Crossref
Crossref
J. Christopher Gallagher, Santiago Palacios, Kelly A. Ryan, Ching-Ray Yu, Kaijie Pan, David L. KendlerSebastian Mirkin & Barry S. Komm. (2016) Effect of conjugated estrogens/bazedoxifene on postmenopausal bone loss: pooled analysis of two randomized trials. Menopause 23:10, pages 1083-1091.
Crossref
Crossref
JoAnn V. Pinkerton, Andrew G. Bushmakin, Lucy Abraham, Joseph C. Cappelleri & Barry S. Komm. (2016) Most bothersome symptom in women with genitourinary syndrome of menopause as a moderator of treatment effects. Menopause 23:10, pages 1092-1101.
Crossref
Crossref
Beate C. Sydora, Hilary Fast, Sandy Campbell, Nese Yuksel, Jacqueline E. LewisSue Ross. (2016) Use of the Menopause-Specific Quality of Life (MENQOL) questionnaire in research and clinical practice: a comprehensive scoping review. Menopause 23:9, pages 1038-1051.
Crossref
Crossref
JoAnn V. Pinkerton, James H. Pickar, Kelly A. Ryan, Ching-Ray YuSebastian Mirkin & Barry S. Komm. (2016) Conjugated estrogens and bazedoxifene in minority populations: pooled analysis of four phase 3 trials. Menopause 23:6, pages 611-620.
Crossref
Crossref
Sebastian MirkinJoAnn V. PinkertonRisa KaganJohn R. ThompsonKaijie PanJames H. PickarBarry S. KommDavid F. Archer. (2016) Gynecologic Safety of Conjugated Estrogens Plus Bazedoxifene: Pooled Analysis of Five Phase 3 Trials. Journal of Women's Health 25:5, pages 431-442.
Crossref
Crossref
Elena M. Umland, Lauren Karel & Nanette Santoro. (2016) Bazedoxifene and Conjugated Equine Estrogen: A Combination Product for the Management of Vasomotor Symptoms and Osteoporosis Prevention Associated with Menopause. Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy 36:5, pages 548-561.
Crossref
Crossref
James H Pickar & Barry S Komm. (2015) Selective estrogen receptor modulators and the combination therapy conjugated estrogens/bazedoxifene: A review of effects on the breast. Post Reproductive Health 21:3, pages 112-121.
Crossref
Crossref
David F. Archer, Bruce R. Carr, JoAnn V. Pinkerton, Hugh S. Taylor & Ginger D. Constantine. (2015) Effects of ospemifene on the female reproductive and urinary tracts. Menopause 22:7, pages 786-796.
Crossref
Crossref
Sven O. Skouby, Kaijie Pan, John R. Thompson, Barry S. Komm & Sebastian Mirkin. (2015) Effects of conjugated estrogens/bazedoxifene on lipid and coagulation variables. Menopause 22:6, pages 640-649.
Crossref
Crossref
Joanne Lester, Gaurav Pahouja, Barbara Andersen & Maryam Lustberg. (2015) Atrophic Vaginitis in Breast Cancer Survivors: A Difficult Survivorship Issue. Journal of Personalized Medicine 5:2, pages 50-66.
Crossref
Crossref
Hee-Jeong Choi. (2015) New Antiresorptive Therapies for Postmenopausal Osteoporosis. Journal of Menopausal Medicine 21:1, pages 1.
Crossref
Crossref
Barry S. Komm, Sebastian Mirkin & Simon N. Jenkins. (2014) Development of conjugated estrogens/bazedoxifene, the first tissue selective estrogen complex (TSEC) for management of menopausal hot flashes and postmenopausal bone loss. Steroids 90, pages 71-81.
Crossref
Crossref
Sebastian Mirkin, David F. Archer, Hugh S. Taylor, James H. Pickar & Barry S. Komm. (2014) Differential effects of menopausal therapies on the endometrium. Menopause 21:8, pages 899-908.
Crossref
Crossref
Andrew G. Bushmakin, Lucy Abraham, JoAnn V. Pinkerton, Joseph C. Cappelleri & Sebastian Mirkin. (2014) Evaluation of the measurement model and clinically important differences for menopause-specific quality of life associated with bazedoxifene/conjugated estrogens. Menopause 21:8, pages 815-822.
Crossref
Crossref
Lucy Abraham, JoAnn V. Pinkerton, Michael Messig, Kelly A. Ryan, Barry S. Komm & Sebastian Mirkin. (2014) Menopause-specific quality of life across varying menopausal populations with conjugated estrogens/bazedoxifene. Maturitas 78:3, pages 212-218.
Crossref
Crossref
Carolyn L Smith, Richard J Santen, Barry Komm & Sebastian Mirkin. (2014) Breast-related effects of selective estrogen receptor modulators and tissue-selective estrogen complexes. Breast Cancer Research 16:3.
Crossref
Crossref
Dennis J. CadaDanial E. Baker. (2014) Conjugated Estrogens and Bazedoxifene. Hospital Pharmacy 49:3, pages 273-283.
Crossref
Crossref
JoAnn V. Pinkerton, Kaijie Pan, Lucy Abraham, Jill Racketa, Kelly A. Ryan, Arkadi A. Chines & Sebastian Mirkin. (2014) Sleep parameters and health-related quality of life with bazedoxifene/conjugated estrogens. Menopause 21:3, pages 252-259.
Crossref
Crossref
JoAnn V. Pinkerton, Jennifer A. Harvey, Robert Lindsay, Kaijie Pan, Arkadi A. Chines, Sebastian Mirkin & David F. Archer. (2014) Effects of Bazedoxifene/Conjugated Estrogens on the Endometrium and Bone: A Randomized Trial. The Journal of Clinical Endocrinology & Metabolism 99:2, pages E189-E198.
Crossref
Crossref
Thomas B. Clarkson, Kelly F. Ethun, Nicholas M. Pajewski, Debbie Golden, Edison Floyd & Susan E. Appt. (2014) Effects of bazedoxifene, conjugated equine estrogens, and a tissue-selective estrogen complex containing both bazedoxifene and conjugated equine estrogens on cerebral artery atherosclerosis in postmenopausal monkeys. Menopause 21:1, pages 8-14.
Crossref
Crossref
JoAnn V. PinkertonLucy AbrahamAndrew G. BushmakinJoseph C. CappelleriJill RacketaHarry ShiArkadi A. ChinesSebastian Mirkin. (2014) Evaluation of the Efficacy and Safety of Bazedoxifene/Conjugated Estrogens for Secondary Outcomes Including Vasomotor Symptoms in Postmenopausal Women by Years Since Menopause in the Selective Estrogens, Menopause and Response to Therapy (SMART) Trials. Journal of Women's Health 23:1, pages 18-28.
Crossref
Crossref
Sebastian Mirkin, Kelly A. Ryan, Arthi B. Chandran & Barry S. Komm. (2014) Bazedoxifene/conjugated estrogens for managing the burden of estrogen deficiency symptoms. Maturitas 77:1, pages 24-31.
Crossref
Crossref
Sebastian Mirkin & Barry S. Komm. (2013) Tissue-selective estrogen complexes for postmenopausal women. Maturitas 76:3, pages 213-220.
Crossref
Crossref
Richard J. Santen, Yan Song, Wei Yue, Ji-Ping Wang & Daniel F. Heitjan. (2013) Effects of menopausal hormonal therapy on occult breast tumors. The Journal of Steroid Biochemistry and Molecular Biology 137, pages 150-156.
Crossref
Crossref
Richard J. Santen, Wei Yue & Daniel F. Heitjan. (2013) Occult Breast Tumor Reservoir: Biological Properties and Clinical Significance. Hormones and Cancer 4:4, pages 195-207.
Crossref
Crossref
Kelly F. Ethun, Charles E. Wood, J. Mark Cline, Thomas C. Register, Susan E. Appt & Thomas B. Clarkson. (2013) Endometrial profile of bazedoxifene acetate alone and in combination with conjugated equine estrogens in a primate model. Menopause 20:7, pages 777-784.
Crossref
Crossref
Carolina O Nastri, Lucia A Lara, Rui A Ferriani, Ana Carolina JS Rosa-e-Silva, Jaqueline BP Figueiredo & Wellington P Martins. (2013) Hormone therapy for sexual function in perimenopausal and postmenopausal women. Cochrane Database of Systematic Reviews.
Crossref
Crossref
Surveen Ghumman. (2013) Atrophic Vaginitis: Diagnosis and Treatment. Journal of SAFOMS 1:1, pages 4-12.
Crossref
Crossref
Thomas P. Burris, Laura A. Solt, Yongjun Wang, Christine Crumbley, Subhashis Banerjee, Kristine Griffett, Thomas Lundasen, Travis Hughes & Douglas J. Kojetin. (2013) Nuclear Receptors and Their Selective Pharmacologic Modulators. Pharmacological Reviews 65:2, pages 710-778.
Crossref
Crossref
Anne Moore. (2013) Advances in menopausal therapy: The tissue-selective estrogen complex. Journal of the American Academy of Nurse Practitioners 25:3, pages 126-133.
Crossref
Crossref
Thomas B. Clarkson, Kelly F. Ethun, Haiying Chen, Debbie Golden, Edison Floyd & Susan E. Appt. (2013) Effects of bazedoxifene alone and with conjugated equine estrogens on coronary and peripheral artery atherosclerosis in postmenopausal monkeys. Menopause 20:3, pages 274-281.
Crossref
Crossref
Yan Song, Richard J. Santen, Ji-ping Wang & Wei Yue. (2013) Inhibitory Effects of a Bazedoxifene/Conjugated Equine Estrogen Combination on Human Breast Cancer Cells In Vitro. Endocrinology 154:2, pages 656-665.
Crossref
Crossref
Yan Song, Richard J. Santen, Ji-ping Wang & Wei Yue. (2012) Effects of the Conjugated Equine Estrogen/Bazedoxifene Tissue-Selective Estrogen Complex (TSEC) on Mammary Gland and Breast Cancer in Mice. Endocrinology 153:12, pages 5706-5715.
Crossref
Crossref
Kelly F. Ethun, Charles E. Wood, Thomas C. Register, J. Mark Cline, Susan E. Appt & Thomas B. Clarkson. (2012) Effects of bazedoxifene acetate with and without conjugated equine estrogens on the breast of postmenopausal monkeys. Menopause 19:11, pages 1242-1252.
Crossref
Crossref
Barry S. Komm & Sebastian Mirkin. (2012) The Tissue Selective Estrogen Complex: A Promising New Menopausal Therapy. Pharmaceuticals 5:9, pages 899-924.
Crossref
Crossref
Risa Kagan. (2012) The Tissue Selective Estrogen Complex: A Novel Approach to the Treatment of Menopausal Symptoms. Journal of Women's Health 21:9, pages 975-981.
Crossref
Crossref
Sebastian Mirkin & James H. Pickar. (2012) The Tissue-Selective Estrogen Complex (TSEC): A Promising New Therapy for Menopausal Symptoms and Postmenopausal Osteoporosis. Current Obstetrics and Gynecology Reports 1:2, pages 50-58.
Crossref
Crossref
Margaret D. Eugenio, Sang-Eun Jun, Kevin C. Cain, Monica E. Jarrett & Margaret M. Heitkemper. (2012) Comprehensive Self-Management Reduces the Negative Impact of Irritable Bowel Syndrome Symptoms on Sexual Functioning. Digestive Diseases and Sciences 57:6, pages 1636-1646.
Crossref
Crossref
Barry S. Komm & Arkadi A. Chines. (2011) Bazedoxifene: the evolving role of third-generation selective estrogen-receptor modulators in the management of postmenopausal osteoporosis. Therapeutic Advances in Musculoskeletal Disease 4:1, pages 21-34.
Crossref
Crossref
Dale W. Stovall, Kirby Tanner-Kurtz & JoAnn V. Pinkerton. (2011) Tissue-Selective Estrogen Complex Bazedoxifene and Conjugated Estrogens for the Treatment of Menopausal Vasomotor Symptoms. Drugs 71:13, pages 1649-1657.
Crossref
Crossref
Jeffrey P. Levine. (2011) Treating Menopausal Symptoms With a Tissue-Selective Estrogen Complex. Gender Medicine 8:2, pages 57-68.
Crossref
Crossref