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Research Article

Design, synthesis, cytotoxic evaluation, and QSAR study of some 6H-indolo[2,3-b]quinoxaline derivatives

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Pages 394-405 | Received 26 Apr 2009, Accepted 17 Jul 2009, Published online: 16 Mar 2010

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Ankush Mishra, S. Singh, M. A. Quraishi & Vandana Srivastava. (2019) A Catalyst-Free Expeditious Green Synthesis of Quinoxaline, Oxazine, Thiazine, and Dioxin Derivatives in Water under Ultrasound Irradiation. Organic Preparations and Procedures International 51:4, pages 345-356.
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N. S. Hari Narayana Moorthy, Vipin Saxena, C. Karthikeyan & Piyush Trivedi. (2012) Synthesis, in silico metabolic and toxicity prediction of some novel imidazolinones derivatives as potent anticonvulsant agents. Journal of Enzyme Inhibition and Medicinal Chemistry 27:2, pages 201-207.
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Ankush KumarBhupinder KumarRohit Bhatia. (2023) Design, Synthesis, Molecular Docking, and Biological Evaluation of Isatin-Based Fused Heterocycles As Epidermal Growth Factor Receptor Inhibitors. ASSAY and Drug Development Technologies 21:5, pages 222-233.
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Vasily E. Melnichenko, Tatyana N. Kudryavtseva, Alexey Y. Lamanov, Timofey A. Kudryavcev & Lyudmila G. Klimova. (2022) Design, synthesis and antimicrobial studies of novel imine derivatives of 2-(6H-indolo[2,3-b]quinoxalin-6-yl)-1-phenylethan-1-ones. Chemical Data Collections 41, pages 100929.
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V. E. Melnichenko, T. N. Kudryavtseva, E. V. Grekhneva, A. Y. Lamanov & T. A. Kudryavcev. (2021) Synthesis of New 2-(6H-Indolo[2,3-b]quinoxalin-6-yl)-1-phenylethane-1-ones. Russian Journal of General Chemistry 91:10, pages 2114-2117.
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Vasily E. Melnichenko, Tatyana N. Kudryavtseva, Alexey Y. Lamanov, Anastasya S. Vanina & Elena V. Grekhnyova. (2021) Synthesis of several new hydroxamic acids containing heterocyclic fragment. Chemical Data Collections 35, pages 100759.
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Kun Liu, Wenxu Song, Yuqi Deng, Huiyue Yang, Chunlan Song, Takfaoui Abdelilah, Shengchun Wang, Hengjiang Cong, Shan Tang & Aiwen Lei. (2020) Electrooxidation enables highly regioselective dearomative annulation of indole and benzofuran derivatives. Nature Communications 11:1.
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N.S. Hari Narayana Moorthy, Udugade B. Vittal, C. Karthikeyan, V. Thangapandian, A.P. Venkadachallam & Piyush Trivedi. (2017) Synthesis, antifungal evaluation and in silico study of novel Schiff bases derived from 4-amino-5(3,5-dimethoxy-phenyl)-4H-1,2,4-triazol-3-thiol. Arabian Journal of Chemistry 10, pages S3239-S3244.
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Deepak Chowrasia, Chandrabose Karthikeyan, Lokesh Choure, Sahabjada, Madhu Gupta, Md Arshad & Piyush Trivedi. (2017) Synthesis, characterization and anti cancer activity of some fluorinated 3,6-diaryl-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazoles. Arabian Journal of Chemistry 10, pages S2424-S2428.
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Chandrabose Karthikeyan, Viswas Raja Solomon, Hoyun Lee & Piyush Trivedi. (2017) Synthesis and biological evaluation of 2-(phenyl)-3H-benzo[d]imidazole-5-carboxylic acids and its methyl esters as potent anti-breast cancer agents. Arabian Journal of Chemistry 10, pages S1788-S1794.
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Zhenyu Gu, Yanci Li, Songliang Ma, Shenghui Li, Guoqiang Zhou, Shan Ding, Jinchao Zhang, Shuxiang Wang & Chuanqi Zhou. (2017) Synthesis, cytotoxic evaluation and DNA binding study of 9-fluoro-6H-indolo[2,3-b]quinoxaline derivatives. RSC Advances 7:66, pages 41869-41879.
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Abby-Jo Payne, Jenny S.J. McCahill & Gregory C. Welch. (2015) Indoloquinoxaline as a terminal building block for the construction of π-conjugated small molecules relevant to organic electronics. Dyes and Pigments 123, pages 139-146.
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Hong Zhang. (2014) A Green Synthesis of Indolo[2,3- b ]Quinoxaline Derivatives . Journal of Chemical Research 38:12, pages 705-709.
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Blanca Estela Duque-Montaño, Lilia Citlalli Gómez-Caro, Mario Sanchez-Sanchez, Antonio Monge, Efrén Hernández-Baltazar, Gildardo Rivera & Oscar Torres-Angeles. (2013) Synthesis and in vitro evaluation of new ethyl and methyl quinoxaline-7-carboxylate 1,4-di-N-oxide against Entamoeba histolytica. Bioorganic & Medicinal Chemistry 21:15, pages 4550-4558.
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N.S. Hari Narayana Moorthy, Sergio F. Sousa, Maria J. Ramos & Pedro A. Fernandes. (2011) In Silico–Based Structural Analysis of Arylthiophene Derivatives for FTase Inhibitory Activity, hERG, and Other Toxic Effects. SLAS Discovery 16:9, pages 1037-1046.
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Vasily Melnichenko, Tatyana N. Kudryavtseva, Alexey Y. Lamanov, Timofey A. Kudryavcev & Lyudmila G. Klimova. (2022) Design, synthesis and antimicrobial studies of novel imine derivatives of 2-(6H-indolo[2,3-b]quinoxalin-6-yl)-1-phenylethan-1-ones. SSRN Electronic Journal.
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