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Journal of Enzyme Inhibition and Medicinal Chemistry Volume 27, 2012 - Issue 1
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Research Article

Novel furfurylidene N-acylhydrazones derived from natural safrole: discovery of LASSBio-1215, a new potent antiplatelet prototype

Ana Paula C. Rodrigues;Laboratório de Avaliação e Síntese de Substâncias Bioativas (LASSBio), Faculdade de Farmácia, Universidade Federal do Rio de Janeiro, Rio de Janeiro, RJ, Brazil
,
Luciana M.M. Costa;Programa de Pós-Graduação em Química, Instituto de Química, Universidade Federal do Rio de Janeiro, Rio de Janeiro, RJ, Brazil
,
Bruna L.R. Santos;Programa de Pós-Graduação em Ciências Farmacêuticas, Faculdade de Farmácia, Universidade Federal do Rio de Janeiro, Rio de Janeiro, RJ, Brazil
,
Rodolfo C. Maia;Programa de Pós-Graduação em Farmacologia e Química Medicinal, Instituto de Ciências Biomédicas, Universidade Federal do Rio de Janeiro, Rio de Janeiro, RJ, Brazil
,
Ana L.P. Miranda;Laboratório de Avaliação e Síntese de Substâncias Bioativas (LASSBio), Faculdade de Farmácia, Universidade Federal do Rio de Janeiro, Rio de Janeiro, RJ, Brazil
,
Eliezer J. Barreiro;Programa de Pós-Graduação em Química, Instituto de Química, Universidade Federal do Rio de Janeiro, Rio de Janeiro, RJ, Brazil
&
Carlos A.M. Fraga;Programa de Pós-Graduação em Ciências Farmacêuticas, Faculdade de Farmácia, Universidade Federal do Rio de Janeiro, Rio de Janeiro, RJ, BrazilCorrespondence[email protected]
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Pages 101-109 | Received 29 Oct 2010, Accepted 04 Apr 2011, Published online: 25 May 2011

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Rodolfo do Couto Maia, Roberta Tesch & Carlos Alberto Manssour Fraga. (2014) Acylhydrazone derivatives: a patent review. Expert Opinion on Therapeutic Patents 24:11, pages 1161-1170.
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Articles from other publishers (5)

Rubina Munir, Sumera Zaib, Muhammad Zia-ur-Rehman, Nadia Hussain, Faryal Chaudhry, Muhammad Tayyab Younas, Fatima Tuz Zahra, Zainab Tajammul, Noman Javid, Ayed A. Dera, Hanan A. Ogaly & Imtiaz Khan. (2023) Ultrasound-Assisted Synthesis of Piperidinyl-Quinoline Acylhydrazones as New Anti-Alzheimer’s Agents: Assessment of Cholinesterase Inhibitory Profile, Molecular Docking Analysis, and Drug-like Properties. Molecules 28:5, pages 2131.
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Chen, Guo, Ma, Chen, Fan & Zhang. (2019) Design, Synthesis, and Biological Evaluation of Novel N-Acylhydrazone Bond Linked Heterobivalent β-Carbolines as Potential Anticancer Agents. Molecules 24:16, pages 2950.
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Cássio S. Meira, José Maurício dos Santos Filho, Caroline C. Sousa, Pâmela S. Anjos, Jéssica V. Cerqueira, Humberto A. Dias Neto, Rafael G. da Silveira, Helena M. Russo, Jean-Luc Wolfender, Emerson F. Queiroz, Diogo R.M. Moreira & Milena B.P. Soares. (2018) Structural design, synthesis and substituent effect of hydrazone-N-acylhydrazones reveal potent immunomodulatory agents. Bioorganic & Medicinal Chemistry 26:8, pages 1971-1985.
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Flávia Pereira Dias Viegas, Matheus de Freitas Silva, Miguel Divino da Rocha, Maísa Rosa Castelli, Mariana Máximo Riquiel, Rafael Pereira Machado, Sarah Macedo Vaz, Laís Medeiros Simões de Lima, Karla Cristine Mancini, Patrícia Cruz Marques de Oliveira, Élida Parreira Morais, Vanessa Silva Gontijo, Fernanda Motta R. da Silva, Dora D'Alincourt da Fonseca Peçanha, Newton Gonçalves Castro, Gilda A. Neves, Alexandre Giusti-Paiva, Fabiana Cardoso Vilela, Lidiane Orlandi, Ihosvany Camps, Márcia Paranho Veloso, Luis Felipe Leomil Coelho, Marisa Ionta, Guilherme Álvaro Ferreira-Silva, Rodrigo Machado Pereira, Laurent E. Dardenne, Isabella Alvim Guedes, Wellerson de Oliveira Carneiro Junior, Paula Maria Quaglio Bellozi, Antônio Carlos Pinheiro de Oliveira, Fábio Furlan Ferreira, Letizia Pruccoli, Andrea Tarozzi & Claudio ViegasJr.Jr.. (2018) Design, synthesis and pharmacological evaluation of N -benzyl-piperidinyl-aryl-acylhydrazone derivatives as donepezil hybrids: Discovery of novel multi-target anti-alzheimer prototype drug candidates. European Journal of Medicinal Chemistry 147, pages 48-65.
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Mohammad Hassam, Abu Taher, Gareth E. Arnott, Ivan R. Green & Willem A. L. van Otterlo. (2015) Isomerization of Allylbenzenes. Chemical Reviews 115:11, pages 5462-5569.
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