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Journal of Enzyme Inhibition and Medicinal Chemistry Volume 27, 2012 - Issue 4
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Short Communications

Antiproliferative activity of some 1,4-dimethylcarbazoles on cells that express estrogen receptors: part I

Anna CarusoDepartment of Pharmaceutical Sciences, University of Calabria, Arcavacata di Rende (CS), Italy
,
Adele ChimentoDepartment of Pharmaco-Biology, University of Calabria, Arcavacata di Rende (CS), Italy
,
Hussein El-KashefChemistry Department, Faculty of Science, Assiut University, Assiut, Egypt
,
Jean-Charles LancelotUniversité de Caen Basse-Normandie, U.F.R. des Sciences Pharmaceutiques, Centre d’Etudes et de Recherche sur le Médicament de Normandie, Boulevard Becquerel, Caen Cedex, France
,
Antonella PannoDepartment of Pharmaceutical Sciences, University of Calabria, Arcavacata di Rende (CS), Italy
,
Vincenzo PezziDepartment of Pharmaco-Biology, University of Calabria, Arcavacata di Rende (CS), Italy
,
Carmela SaturninoDepartment of Pharmaceutical and Biomedical Sciences, University of Salerno, Fisciano (SA), Italy
,
Maria Stefania SinicropiDepartment of Pharmaceutical Sciences, University of Calabria, Arcavacata di Rende (CS), ItalyCorrespondence[email protected]
,
Rosa SirianniDepartment of Pharmaco-Biology, University of Calabria, Arcavacata di Rende (CS), Italy
&
Sylvain RaultUniversité de Caen Basse-Normandie, U.F.R. des Sciences Pharmaceutiques, Centre d’Etudes et de Recherche sur le Médicament de Normandie, Boulevard Becquerel, Caen Cedex, France
 show all
Pages 609-613 | Received 09 Jun 2011, Accepted 29 Jun 2011, Published online: 02 Sep 2011

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Maria Stefania Sinicropi, Domenico Iacopetta, Camillo Rosano, Rosario Randino, Anna Caruso, Carmela Saturnino, Noemi Muià, Jessica Ceramella, Francesco Puoci, Manuela Rodriquez, Pasquale Longo & Maria Rosaria Plutino. (2018) N-thioalkylcarbazoles derivatives as new anti-proliferative agents: synthesis, characterisation and molecular mechanism evaluation. Journal of Enzyme Inhibition and Medicinal Chemistry 33:1, pages 434-444.
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Articles from other publishers (30)

Jessica Ceramella, Domenico Iacopetta, Anna Caruso, Annaluisa Mariconda, Anthi Petrou, Athina Geronikaki, Camillo Rosano, Carmela Saturnino, Alessia Catalano, Pasquale Longo & Maria Stefania Sinicropi. (2023) 5,8-Dimethyl-9H-carbazole Derivatives Blocking hTopo I Activity and Actin Dynamics. Pharmaceuticals 16:3, pages 353.
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Maria Grazia Bonomo, Anna Caruso, Hussein El-Kashef, Giovanni Salzano, Maria Stefania Sinicropi & Carmela Saturnino. (2023) An Update of Carbazole Treatment Strategies for COVID-19 Infection. Applied Sciences 13:3, pages 1522.
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Fedora Grande, Giuseppina Ioele, Anna Caruso, Maria Antonietta Occhiuzzi, Hussein El-Kashef, Carmela Saturnino & Maria Stefania Sinicropi. (2022) Carbazoles: Role and Functions in Fighting Diabetes. Applied Sciences 13:1, pages 349.
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Yun-Peng Xie, Nagarajan Sangaraiah, Jiang-Ping Meng & Cheng-He Zhou. (2022) Unique Carbazole-Oxadiazole Derivatives as New Potential Antibiotics for Combating Gram-Positive and -Negative Bacteria. Journal of Medicinal Chemistry 65:8, pages 6171-6190.
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Fedora Grande, Anna De Bartolo, Maria Antonietta Occhiuzzi, Anna Caruso, Carmine Rocca, Teresa Pasqua, Alessia Carocci, Vittoria Rago, Tommaso Angelone & Maria Stefania Sinicropi. (2021) Carbazole and Simplified Derivatives: Novel Tools toward β-Adrenergic Receptors Targeting. Applied Sciences 11:12, pages 5486.
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Yun-Peng Xie, Mohammad Fawad Ansari, Shao-Lin Zhang & Cheng-He Zhou. (2021) Novel carbazole-oxadiazoles as potential Staphylococcus aureus germicides. Pesticide Biochemistry and Physiology 175, pages 104849.
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Libang Liang, Guanqiao Wang, Bradley Haltli, Douglas H. Marchbank, Henrik Stryhn, Hebelin Correa & Russell G. Kerr. (2020) Metabolomic Comparison and Assessment of Co-cultivation and a Heat-Killed Inducer Strategy in Activation of Cryptic Biosynthetic Pathways. Journal of Natural Products 83:9, pages 2696-2705.
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Jessica Ceramella, Domenico Iacopetta, Alexia Barbarossa, Anna Caruso, Fedora Grande, Maria Grazia Bonomo, Annaluisa Mariconda, Pasquale Longo, Saturnino Carmela & Maria Stefania Sinicropi. (2020) Carbazole Derivatives as Kinase-Targeting Inhibitors for Cancer Treatment. Mini-Reviews in Medicinal Chemistry 20:6, pages 444-465.
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Jessica Ceramella, Anna Caruso, Maria Antonietta Occhiuzzi, Domenico Iacopetta, Alexia Barbarossa, Bruno Rizzuti, Patrick Dallemagne, Sylvain Rault, Hussein El-Kashef, Carmela Saturnino, Fedora Grande & Maria Stefania Sinicropi. (2019) Benzothienoquinazolinones as new multi-target scaffolds: Dual inhibition of human Topoisomerase I and tubulin polymerization. European Journal of Medicinal Chemistry 181, pages 111583.
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Anna Caruso, Jessica Ceramella, Domenico Iacopetta, Carmela Saturnino, Maria Vittoria Mauro, Rosalinda Bruno, Stefano Aquaro & Maria Stefania Sinicropi. (2019) Carbazole Derivatives as Antiviral Agents: An Overview. Molecules 24:10, pages 1912.
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Carmela Saturnino, Anna Caruso, Domenico Iacopetta, Camillo Rosano, Jessica Ceramella, Noemi Muià, Annaluisa Mariconda, Maria Grazia Bonomo, Marco Ponassi, Giuseppe Rosace, Maria Stefania Sinicropi & Pasquale Longo. (2018) Inhibition of Human Topoisomerase II by N , N , N -Trimethylethanammonium Iodide Alkylcarbazole Derivatives . ChemMedChem 13:24, pages 2635-2643.
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Cornelis P. Vlaar, Linette Castillo-Pichardo, Julia I. Medina, Cathyria M. Marrero-Serra, Ericka Vélez, Zulma Ramos & Eliud Hernández. (2018) Design, synthesis and biological evaluation of new carbazole derivatives as anti-cancer and anti-migratory agents. Bioorganic & Medicinal Chemistry 26:4, pages 884-890.
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Domenico Iacopetta, Annaluisa Mariconda, Carmela Saturnino, Anna Caruso, Giuseppe Palma, Jessica Ceramella, Noemi Muià, Mariarita Perri, Maria Stefania Sinicropi, Maria Cristina Caroleo & Pasquale Longo. (2017) Novel Gold and Silver Carbene Complexes Exert Antitumor Effects Triggering the Reactive Oxygen Species Dependent Intrinsic Apoptotic Pathway. ChemMedChem 12:24, pages 2054-2065.
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R. Tundis, D. Iacopetta, M.S. Sinicropi, M. Bonesi, M. Leporini, N.G. Passalacqua, J. Ceramella, F. Menichini & M.R. Loizzo. (2017) Assessment of antioxidant, antitumor and pro-apoptotic effects of Salvia fruticosa Mill. subsp. thomasii (Lacaita) Brullo, Guglielmo, Pavone & Terrasi (Lamiaceae). Food and Chemical Toxicology 106, pages 155-164.
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Vijay Kumar Reddy Avula, Swetha Vallela, Jaya Shree Anireddy & Naga Raju Chamarthi. (2017) A Green Synthesis of 2-Amino-4-(9 H -carbazole-3-yl)thiophene-3-carbonitriles by a Step-wise and One-pot Three-component Gewald Reaction . Journal of Heterocyclic Chemistry 54:4, pages 2471-2482.
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Domenico Iacopetta, Camillo Rosano, Francesco Puoci, Ortensia Ilaria Parisi, Carmela Saturnino, Anna Caruso, Pasquale Longo, Jessica Ceramella, Aurélie Malzert-Fréon, Patrick Dallemagne, Sylvain Rault & Maria Stefania Sinicropi. (2017) Multifaceted properties of 1,4-dimethylcarbazoles: Focus on trimethoxybenzamide and trimethoxyphenylurea derivatives as novel human topoisomerase II inhibitors. European Journal of Pharmaceutical Sciences 96, pages 263-272.
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Carmela Saturnino, Ines Barone, Domenico Iacopetta, Annaluisa Mariconda, Maria Stefania Sinicropi, Camillo Rosano, Antonella Campana, Stefania Catalano, Pasquale Longo & Sebastiano Andò. (2016) N -heterocyclic carbene complexes of silver and gold as novel tools against breast cancer progression . Future Medicinal Chemistry 8:18, pages 2213-2229.
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Michela Falco, Giuseppe Palma, Domenica Rea, Davide De Biase, Stefania Scala, Massimiliano D'Aiuto, Gaetano Facchini, Sisto Perdonà, Antonio Barbieri & Claudio Arra. (2016) Tumour biomarkers: homeostasis as a novel prognostic indicator. Open Biology 6:12, pages 160254.
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Pietro Rizza, Michele Pellegrino, Anna Caruso, Domenico Iacopetta, Maria Stefania Sinicropi, Sylvain Rault, Jean Charles Lancelot, Hussein El-Kashef, Aurelien Lesnard, Christophe Rochais, Patrick Dallemagne, Carmela Saturnino, Francesca Giordano, Stefania Catalano & Sebastiano Andò. (2016) 3-(Dipropylamino)-5-hydroxybenzofuro[2,3-f]quinazolin-1(2H)-one (DPA-HBFQ-1) plays an inhibitory role on breast cancer cell growth and progression. European Journal of Medicinal Chemistry 107, pages 275-287.
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Adele Chimento, Carmela Saturnino, Domenico Iacopetta, Rosaria Mazzotta, Anna Caruso, Maria Rosaria Plutino, Annaluisa Mariconda, Anna Ramunno, Maria Stefania Sinicropi, Vincenzo Pezzi & Pasquale Longo. (2015) Inhibition of human topoisomerase I and II and anti-proliferative effects on MCF-7 cells by new titanocene complexes. Bioorganic & Medicinal Chemistry 23:22, pages 7302-7312.
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Pannala Padmaja, Garikapati Koteswara Rao, Adisherla Indrasena, Basireddy V. Subba Reddy, Nibedita Patel, Anver Basha Shaik, Narayana Reddy, Pramod K. Dubey & Manika Pal Bhadra. (2015) Synthesis and biological evaluation of novel pyrano[3,2-c]carbazole derivatives as anti-tumor agents inducing apoptosis via tubulin polymerization inhibition. Organic & Biomolecular Chemistry 13:5, pages 1404-1414.
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Antonella Panno, Maria Stefania Sinicropi, Anna Caruso, Hussein El-Kashef, Jean-Charles Lancelot, Geneviève Aubert, Aurélien Lesnard, Thierry Cresteil & Sylvain Rault. (2014) New Trimethoxybenzamides and Trimethoxyphenylureas Derived from Dimethylcarbazole as Cytotoxic Agents. Part I. Journal of Heterocyclic Chemistry 51:S1, pages E294-E302.
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Carmela Saturnino, Domenico Iacopetta, Maria Sinicropi, Camillo Rosano, Anna Caruso, Angelamaria Caporale, Nancy Marra, Barbara Marengo, Maria Pronzato, Ortensia Parisi, Pasquale Longo & Roberta Ricciarelli. (2014) N-Alkyl Carbazole Derivatives as New Tools for Alzheimer’s Disease: Preliminary Studies. Molecules 19:7, pages 9307-9317.
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Carmela Saturnino, Maria Stefania Sinicropi, Ortensia Ilaria Parisi, Domenico Iacopetta, Ada Popolo, Stefania Marzocco, Giuseppina Autore, Anna Caruso, Anna Rita Cappello, Pasquale Longo & Francesco Puoci. (2014) Acetylated Hyaluronic Acid: Enhanced Bioavailability and Biological Studies. BioMed Research International 2014, pages 1-7.
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Ortensia Ilaria Parisi, Catia Morelli, Francesco Puoci, Carmela Saturnino, Anna Caruso, Diego Sisci, Giovanna Elvi Trombino, Nevio Picci & Maria Stefania Sinicropi. (2014) Magnetic molecularly imprinted polymers (MMIPs) for carbazole derivative release in targeted cancer therapy. J. Mater. Chem. B 2:38, pages 6619-6625.
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Anna Caruso, Maria Stefania Sinicropi, Jean-Charles Lancelot, Hussein El-Kashef, Carmela Saturnino, Geneviève Aubert, Céline Ballandonne, Aurélien Lesnard, Thierry Cresteil, Patrick Dallemagne & Sylvain Rault. (2014) Synthesis and evaluation of cytotoxic activities of new guanidines derived from carbazoles. Bioorganic & Medicinal Chemistry Letters 24:2, pages 467-472.
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Carmela Saturnino, Esther Sirignano, Antonio Botta, Maria Stefania Sinicropi, Anna Caruso, Assunta Pisano, Rosamaria Lappano, Marcello Maggiolini & Pasquale Longo. (2014) New titanocene derivatives with high antiproliferative activity against breast cancer cells. Bioorganic & Medicinal Chemistry Letters 24:1, pages 136-140.
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Adele Chimento, Marina Sala, Isabel M. Gomez-Monterrey, Simona Musella, Alessia Bertamino, Anna Caruso, Maria Stefania Sinicropi, Rosa Sirianni, Francesco Puoci, Ortensia Ilaria Parisi, Carmela Campana, Emilia Martire, Ettore Novellino, Carmela Saturnino, Pietro Campiglia & Vincenzo Pezzi. (2013) Biological activity of 3-chloro-azetidin-2-one derivatives having interesting antiproliferative activity on human breast cancer cell lines. Bioorganic & Medicinal Chemistry Letters 23:23, pages 6401-6405.
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Marina Sala, Adele Chimento, Carmela Saturnino, Isabel M. Gomez-Monterrey, Simona Musella, Alessia Bertamino, Ciro Milite, Maria Stefania Sinicropi, Anna Caruso, Rosa Sirianni, Paolo Tortorella, Ettore Novellino, Pietro Campiglia & Vincenzo Pezzi. (2013) Synthesis and cytotoxic activity evaluation of 2,3-thiazolidin-4-one derivatives on human breast cancer cell lines. Bioorganic & Medicinal Chemistry Letters 23:17, pages 4990-4995.
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Esther Sirignano, Carmela Saturnino, Antonio Botta, Maria Stefania Sinicropi, Anna Caruso, Assunta Pisano, Rosamaria Lappano, Marcello Maggiolini & Pasquale Longo. (2013) Synthesis, characterization and cytotoxic activity on breast cancer cells of new half-titanocene derivatives. Bioorganic & Medicinal Chemistry Letters 23:11, pages 3458-3462.
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