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Journal of Enzyme Inhibition and Medicinal Chemistry Volume 27, 2012 - Issue 1
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Short Communication

The crystal structure of protease Sapp1p from Candida parapsilosis in complex with the HIV protease inhibitor ritonavir

Jiří Dostál;Institute of Organic Chemistry and Biochemistry, Academy of Sciences of the Czech Republic, v.v.i., Prague, Czech Republic
,
Jiří Brynda;IOCB & Gilead Research Centre, Prague, Czech Republic
,
Olga Hrušková-Heidingsfeldová;Institute of Molecular Genetics, Academy of Sciences of the Czech Republic, Prague, Czech Republic
,
Petr Pachl;Institute of Organic Chemistry and Biochemistry, Academy of Sciences of the Czech Republic, v.v.i., Prague, Czech Republic
,
Iva Pichová;IOCB & Gilead Research Centre, Prague, Czech Republic
&
Pavlína Řezáčová;Institute of Molecular Genetics, Academy of Sciences of the Czech Republic, Prague, Czech RepublicCorrespondence[email protected]
Pages 160-165 | Received 02 Sep 2011, Accepted 19 Sep 2011, Published online: 06 Dec 2011

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Jiří Dostál, Jiří Brynda, Lucie Vaňková, Syeda Rehana Zia, Iva Pichová, Olga Heidingsfeld & Martin Lepšík. (2021) Structural determinants for subnanomolar inhibition of the secreted aspartic protease Sapp1p from Candida parapsilosis. Journal of Enzyme Inhibition and Medicinal Chemistry 36:1, pages 914-921.
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Marcela Q. Granato, Ingrid S. Sousa, Thabatta L. S. A. Rosa, Diego S. Gonçalves, Sergio H. Seabra, Daniela S. Alviano, Maria C. V. Pessolani, André L. S. Santos & Lucimar F. Kneipp. (2020) Aspartic peptidase of Phialophora verrucosa as target of HIV peptidase inhibitors: blockage of its enzymatic activity and interference with fungal growth and macrophage interaction. Journal of Enzyme Inhibition and Medicinal Chemistry 35:1, pages 629-638.
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Chiara Calugi, Antonio Guarna & Andrea Trabocchi. (2013) Insight into the structural similarity between HIV protease and secreted aspartic protease-2 and binding mode analysis of HIV-Candida albicans inhibitors. Journal of Enzyme Inhibition and Medicinal Chemistry 28:5, pages 936-943.
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Articles from other publishers (5)

Si Jie Lim, Mohd Shukuri Mohamad Ali, Suriana Sabri, Noor Dina Muhd Noor, Abu Bakar Salleh & Siti Nurbaya Oslan. (2021) Opportunistic yeast pathogen Candida spp.: Secreted and membrane-bound virulence factors . Medical Mycology 59:12, pages 1127-1144.
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André L. S. Santos, Lys A. Braga-Silva, Diego S. Gonçalves, Lívia S. Ramos, Simone S. C. Oliveira, Lucieri O. P. Souza, Vanessa S. Oliveira, Roberto D. Lins, Marcia R. Pinto, Julian E. Muñoz, Carlos P. Taborda & Marta H. Branquinha. (2021) Repositioning Lopinavir, an HIV Protease Inhibitor, as a Promising Antifungal Drug: Lessons Learned from Candida albicans—In Silico, In Vitro and In Vivo Approaches. Journal of Fungi 7:6, pages 424.
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M. Rapala‐Kozik, O. Bochenska, D. Zajac, J. Karkowska‐Kuleta, M. Gogol, M. Zawrotniak & A. Kozik. (2018) Extracellular proteinases of Candida species pathogenic yeasts . Molecular Oral Microbiology 33:2, pages 113-124.
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Jiří Dostál, Adam Pecina, Olga Hrušková-Heidingsfeldová, Lucie Marečková, Iva Pichová, Pavlina Řezáčová, Martin Lepšík & Jiří Brynda. (2015) Atomic resolution crystal structure of Sapp2p, a secreted aspartic protease from Candida parapsilosis . Acta Crystallographica Section D Biological Crystallography 71:12, pages 2494-2504.
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Tonny C. C. Leite, Franco H. A. Leite, Ivo J. C. Vieira, Raimundo Braz Filho & Alexsandro Branco. (2013) New Cycloartane-type Triterpenes from Marcetia Latifolia (Melastomataceae) and In Silico Studies on Candida Parapsilosis Protease . Natural Product Communications 8:8, pages 1934578X1300800.
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