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Özcan Güleç, Cüneyt Türkeş, Mustafa Arslan, Yeliz Demir, Busra Dincer, Abdulilah Ece & Şükrü Beydemir. (2023) Novel beta-lactam substituted benzenesulfonamides: in vitro enzyme inhibition, cytotoxic activity and in silico interactions. Journal of Biomolecular Structure and Dynamics 0:0, pages 1-19.
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Joey G. Sheff, John F. Kelly, Anna Robotham, Traian Sulea, Félix Malenfant, Denis L’Abbé, Mélanie Duchesne, Alex Pelletier, Jean Lefebvre, Andrea Acel, Marie Parat, Mylene Gosselin, Cunle Wu, Yves Fortin, Jason Baardsnes, Henk Van Faassen, Shannon Awrey, Shawn C. Chafe, Paul C. McDonald, Shoukat Dedhar & Anne E.G. Lenferink. (2021) Hydrogen-deuterium exchange mass spectrometry reveals three unique binding responses of mAbs directed to the catalytic domain of hCAIX. mAbs 13:1.
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Anna Di Fiore, Claudiu T. Supuran, Andrea Scaloni & Giuseppina De Simone. (2020) Human carbonic anhydrases and post-translational modifications: a hidden world possibly affecting protein properties and functions. Journal of Enzyme Inhibition and Medicinal Chemistry 35:1, pages 1450-1461.
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Ashok Aspatwar, Nanda Kumar Parvathaneni, Harlan Barker, Emilie Anduran, Claudiu T. Supuran, Ludwig Dubois, Philippe Lambin, Seppo Parkkila & Jean-Yves Winum. (2020) Design, synthesis, in vitro inhibition and toxicological evaluation of human carbonic anhydrases I, II and IX inhibitors in 5-nitroimidazole series. Journal of Enzyme Inhibition and Medicinal Chemistry 35:1, pages 109-117.
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Alessio Nocentini & Claudiu T. Supuran. (2019) Advances in the structural annotation of human carbonic anhydrases and impact on future drug discovery. Expert Opinion on Drug Discovery 14:11, pages 1175-1197.
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Giuseppina De Simone, Anna Di Fiore, Emanuela Truppo, Emma Langella, Daniela Vullo, Claudiu T. Supuran & Simona Maria Monti. (2019) Exploration of the residues modulating the catalytic features of human carbonic anhydrase XIII by a site-specific mutagenesis approach. Journal of Enzyme Inhibition and Medicinal Chemistry 34:1, pages 1506-1510.
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Arun John, Muthukumaran Sivashanmugam, Vetrivel Umashankar & Sulochana Konerirajapuram Natarajan. (2017) Virtual screening, molecular dynamics, and binding free energy calculations on human carbonic anhydrase IX catalytic domain for deciphering potential leads. Journal of Biomolecular Structure and Dynamics 35:10, pages 2155-2168.
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Justina Kazokaitė, Ashok Aspatwar, Visvaldas Kairys, Seppo Parkkila & Daumantas Matulis. (2017) Fluorinated benzenesulfonamide anticancer inhibitors of carbonic anhydrase IX exhibit lower toxic effects on zebrafish embryonic development than ethoxzolamide. Drug and Chemical Toxicology 40:3, pages 309-319.
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P. V. Sri Ramya, Srinivas Angapelly, Andrea Angeli, Chander Singh Digwal, Mohammed Arifuddin, Bathini Nagendra Babu, Claudiu T. Supuran & Ahmed Kamal. (2017) Discovery of curcumin inspired sulfonamide derivatives as a new class of carbonic anhydrase isoforms I, II, IX, and XII inhibitors. Journal of Enzyme Inhibition and Medicinal Chemistry 32:1, pages 1274-1281.
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Justina Kazokaitė, Samantha Ames, Holger M. Becker, Joachim W. Deitmer & Daumantas Matulis. (2016) Selective inhibition of human carbonic anhydrase IX in Xenopus oocytes and MDA-MB-231 breast cancer cells. Journal of Enzyme Inhibition and Medicinal Chemistry 31:sup4, pages 38-44.
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Alessio Nocentini, Mariangela Ceruso, Fabrizio Carta & Claudiu T. Supuran. (2016) 7-Aryl-triazolyl-substituted sulfocoumarins are potent, selective inhibitors of the tumor-associated carbonic anhydrase IX and XII. Journal of Enzyme Inhibition and Medicinal Chemistry 31:6, pages 1226-1233.
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Ramin Ekhteiari Salmas, Mert Mestanoglu, Serdar Durdagi, Murat Sentürk, A. Afşin Kaya & Elif Çelenk Kaya. (2016) Kinetic and in silico studies of hydroxy-based inhibitors of carbonic anhydrase isoforms I and II. Journal of Enzyme Inhibition and Medicinal Chemistry 31:1, pages 31-37.
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Giuseppina De Simone, Vincenzo Alterio & Claudiu T Supuran. (2013) Exploiting the hydrophobic and hydrophilic binding sites for designing carbonic anhydrase inhibitors. Expert Opinion on Drug Discovery 8:7, pages 793-810.
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Emanuela Masini, Fabrizio Carta, Andrea Scozzafava & Claudiu T Supuran. (2013) Antiglaucoma carbonic anhydrase inhibitors: a patent review. Expert Opinion on Therapeutic Patents 23:6, pages 705-716.
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Mayank Aggarwal, Bhargav Kondeti & Robert McKenna. (2013)
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Fabrizio Carta & Claudiu T Supuran. (2013) Diuretics with carbonic anhydrase inhibitory action: a patent and literature review (2005 – 2013). Expert Opinion on Therapeutic Patents 23:6, pages 681-691.
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Simone Parn, Gabriela Lewis & Matty Knight. (2023) Inhibition of carbonic anhydrase using aspirin is a novel method to block schistosomiasis infection of the parasitic trematode, Schistosoma mansoni, in the intermediate snail host, Biomphalaria glabrata. Experimental Parasitology 254, pages 108618.
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Arjun Sharma, Rong-an Chiang, Monica Manginell, Isaac Nardi, Eric N. Coker, Juan M. Vanegas, Susan B. Rempe & George D. Bachand. (2023)
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Samir Bondock, Tallah Albarqi, Mohamed Abboud, Tamer Nasr, Nada M. Mohamed & Moaz M. Abdou. (2023) Tail-approach based design, synthesis, and cytotoxic evaluation of novel disubstituted and trisubstituted 1,3-thiazole benzenesulfonamide derivatives with suggested carbonic anhydrase IX inhibition mechanism. RSC Advances 13:34, pages 24003-24022.
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Wenjia Zhu, Xiaoyuan Li, Guoyang Zheng, Chunmei Bai, Zhigang Ji, Haiqiong Zhang, Haiqun Xing, Yushi Zhang & Li Huo. (2023) Preclinical and pilot clinical evaluation of a small-molecule carbonic anhydrase IX targeting PET tracer in clear cell renal cell carcinoma. European Journal of Nuclear Medicine and Molecular Imaging 50:10, pages 3116-3125.
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Laura Edit Barabás, Diana Maria Scrob, Andrea Varga, Loránd Kiss, Monica Ioana Toşa & Csaba Paizs. (2023)
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Sebastian Oehler, Laura Lucaroni, Francesca Migliorini, Abdullah Elsayed, Luca Prati, Sara Puglioli, Mattia Matasci, Kristina Schira, Jörg Scheuermann, Denis Yudin, Min Jia, Nenad Ban, Dave Bushnell, Roger Kornberg, Samuele Cazzamalli, Dario Neri, Nicholas Favalli & Gabriele Bassi. (2023) A DNA-encoded chemical library based on chiral 4-amino-proline enables stereospecific isozyme-selective protein recognition. Nature Chemistry.
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Büşra ÇALIŞKAN, Mine AKSOY, Muhammet Serhat ÖZASLAN & İlknur AKYOL SALMAN. (2023) Investigation of Some Metabolic Enzyme Activities in Samples of Serum and Humor Aqueous of Cataract Cases with Pseudoexfoliation Syndrome. Türk Doğa ve Fen Dergisi 12:1, pages 163-170.
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Thomas J Summers & Nathan J DeYonker. (2023)
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Conor B. O’Herin, Yuta W. Moriuchi, Troy A. Bemis, Alysia J. Kohlbrand, Michael D. Burkart & Seth M. Cohen. (2023) Development of Human Carbonic Anhydrase II Heterobifunctional Degraders. Journal of Medicinal Chemistry 66:4, pages 2789-2803.
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Davide Ialongo, Antonella Messore, Valentina Noemi Madia, Valeria Tudino, Alessio Nocentini, Paola Gratteri, Simone Giovannuzzi, Claudiu T. Supuran, Alice Nicolai, Susanna Scarpa, Samanta Taurone, Michele Camarda, Marco Artico, Veronica Papa, Francesco Saccoliti, Luigi Scipione, Roberto Di Santo & Roberta Costi. (2023) Pyrrolyl and Indolyl α-γ-Diketo Acid Derivatives Acting as Selective Inhibitors of Human Carbonic Anhydrases IX and XII. Pharmaceuticals 16:2, pages 188.
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Katja Eloranta, Marjut Pihlajoki, Emmi Liljeström, Ruth Nousiainen, Tea Soini, Jouko Lohi, Stefano Cairo, David B. Wilson, Seppo Parkkila & Markku Heikinheimo. (2023) SLC-0111, an inhibitor of carbonic anhydrase IX, attenuates hepatoblastoma cell viability and migration. Frontiers in Oncology 13.
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Mudasir Nabi Peerzada, Masood Ahmad Rizvi, Ajeesh Kumar KK, Ankita Sahu & Saurabh Verma. 2023. Nature-Inspired Intelligent Computing Techniques in Bioinformatics. Nature-Inspired Intelligent Computing Techniques in Bioinformatics
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Saniya Zaidi, Nitin Srivastava & Sunil Kumar Khare. (2022) Microbial carbonic anhydrase mediated carbon capture, sequestration & utilization: A sustainable approach to delivering bio-renewables. Bioresource Technology 365, pages 128174.
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Alma Yrjänäinen, Maarit S. Patrikainen, Latifeh Azizi, Martti E. E. Tolvanen, Mikko Laitaoja, Janne Jänis, Vesa P. Hytönen, Alessio Nocentini, Claudiu T. Supuran & Seppo Parkkila. (2022) Biochemical and Biophysical Characterization of Carbonic Anhydrase VI from Human Milk and Saliva. The Protein Journal 41:4-5, pages 489-503.
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Divya Rai, Satyajit Khatua & Srabani Taraphder. (2022) Structure and Dynamics of the Isozymes II and IX of Human Carbonic Anhydrase. ACS Omega 7:35, pages 31149-31166.
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Sümeyye Çol, Mustafa Emirik, Zuhal Alım & Arif Baran. (2022)
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Mohamed Reda Aouad, Meshal A. Almehmadi, Fawzia Faleh Albelwi, Mohamed Teleb, Gina N. Tageldin, Marwa M. Abu-Serie, Mohamed Hagar & Nadjet Rezki. (2022) Targeting the interplay between MMP-2, CA II and VEGFR-2 via new sulfonamide-tethered isomeric triazole hybrids; Microwave-assisted synthesis, computational studies and evaluation. Bioorganic Chemistry 124, pages 105816.
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Jan Hedner, Kaj StenlöfDing ZouErik Hoff, Corinna Hansen, Katrin Kuhn, Peter Lennartz & Ludger Grote. (2022) A Randomized Controlled Clinical Trial Exploring Safety and Tolerability of Sulthiame in Sleep Apnea. American Journal of Respiratory and Critical Care Medicine 205:12, pages 1461-1469.
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Mohamed Nabil Abd Al Moaty, El Sayed Helmy El Ashry, Laila Fathy Awad, Nihal Ahmed Ibrahim, Marwa Muhammad Abu-Serie, Assem Barakat, Mezna Saleh Altowyan & Mohamed Teleb. (2022) Enhancing the Anticancer Potential of Targeting Tumor-Associated Metalloenzymes via VEGFR Inhibition by New Triazolo[4,3-a]pyrimidinone Acyclo C-Nucleosides Multitarget Agents. Molecules 27:8, pages 2422.
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Anna Di Fiore, Claudiu T. Supuran, Andrea Scaloni & Giuseppina De Simone. (2021) Post-translational modifications in tumor-associated carbonic anhydrases. Amino Acids 54:4, pages 543-558.
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Pengcheng Lv, Yinyi Cai, Jiayi Luo & Kun Chen. (2022) Recent Advances in the Design and Synthesis of Small Molecule Carbonic
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Kashif Rafiq, Najeeb Ur Rehman, Sobia Ahsan Halim, Majid Khan, Ajmal Khan & Ahmed Al-Harrasi. (2022) Design, Synthesis and Molecular Docking Study of Novel 3-Phenyl-β-Alanine-Based Oxadiazole Analogues as Potent Carbonic Anhydrase II Inhibitors. Molecules 27:3, pages 816.
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Fatma AYDIN, Zeynep Aleyna KAHRAMAN, Emir Alper TÜRKOĞLU, Müslüm KUZU & Zeki SEVEROĞLU. (2021) In vitro antioxidant activity and carbonic anhydrase inhibitory features of Ferula communis extracts. International Journal of Agriculture Environment and Food Sciences 5:4, pages 592-598.
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Annachiara Tinivella, Luca Pinzi & Giulio Rastelli. (2021) Prediction of activity and selectivity profiles of human Carbonic Anhydrase inhibitors using machine learning classification models. Journal of Cheminformatics 13:1.
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Moataz Shaldam, Alessio Nocentini, Zainab M. Elsayed, Tamer M. Ibrahim, Rofaida Salem, Ramadan A. El-Domany, Clemente Capasso, Claudiu T. Supuran & Wagdy M. Eldehna. (2021) Development of Novel Quinoline-Based Sulfonamides as Selective Cancer-Associated Carbonic Anhydrase Isoform IX Inhibitors. International Journal of Molecular Sciences 22:20, pages 11119.
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Lina Baranauskiene, Lina Škiudaitė, Vilma Michailovienė, Vytautas Petrauskas & Daumantas Matulis. (2021) Thiazide and other Cl-benzenesulfonamide-bearing clinical drug affinities for human carbonic anhydrases. PLOS ONE 16:6, pages e0253608.
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Satya Kumar Avula, Najeeb Ur Rehman, Majid Khan, Sobia Ahsan Halim, Ajmal Khan, Kashif Rafiq, René Csuk, Biswanath Das & Ahmed Al-Harrasi. (2021) New synthetic 1H-1,2,3-triazole derivatives of 3-O-acetyl-β-boswellic acid and 3-O-acetyl-11-keto-β-boswellic acid from Boswellia sacra inhibit carbonic anhydrase II in vitro. Medicinal Chemistry Research 30:6, pages 1185-1198.
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Justina Kazokaitė-Adomaitienė, Holger M. Becker, Joana Smirnovienė, Ludwig J. Dubois & Daumantas Matulis. (2021) Experimental Approaches to Identify Selective Picomolar Inhibitors for Carbonic Anhydrase IX. Current Medicinal Chemistry 28:17, pages 3361-3384.
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Ajmal Khan, Majid Khan, Sobia Ahsan Halim, Zulfiqar Ali Khan, Zahid Shafiq & Ahmed Al-Harrasi. (2020) Quinazolinones as Competitive Inhibitors of Carbonic Anhydrase-II (Human and Bovine): Synthesis, in-vitro, in-silico, Selectivity, and Kinetics Studies. Frontiers in Chemistry 8.
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Anand Giri, Veerbala Sharma, Shabnam Thakur, Tanvi Sharma, Ashok Kumar & Deepak Pant. 2020. Chemo-Biological Systems for CO2 Utilization. Chemo-Biological Systems for CO2 Utilization
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Erik Hoff, Ding Zou, Sophia Schiza, Yeliz Demir, Ludger Grote, Izolde Bouloukaki, Şükrü Beydemir, Davoud Eskandari, Kaj Stenlöf & Jan Hedner. (2019) Carbonic anhydrase, obstructive sleep apnea and hypertension: Effects of intervention. Journal of Sleep Research 29:2.
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Benas Balandis, Guostė Ivanauskaitė, Joana Smirnovienė, Kristina Kantminienė, Daumantas Matulis, Vytautas Mickevičius & Asta Zubrienė. (2020) Synthesis and structure–affinity relationship of chlorinated pyrrolidinone-bearing benzenesulfonamides as human carbonic anhydrase inhibitors. Bioorganic Chemistry 97, pages 103658.
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Heba T. Abdel-Mohsen, Ahmed M. El Kerdawy, Mohamed A. Omar, Emanuela Berrino, Ahmed S. Abdelsamie, Hoda I. El Diwani & Claudiu T. Supuran. (2020) New thiopyrimidine-benzenesulfonamide conjugates as selective carbonic anhydrase II inhibitors: synthesis, in vitro biological evaluation, and molecular docking studies. Bioorganic & Medicinal Chemistry 28:5, pages 115329.
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Audrius Zakšauskas, Edita Čapkauskaitė, Linas Jezepčikas, Vaida Linkuvienė, Vaida Paketurytė, Alexey Smirnov, Janis Leitans, Andris Kazaks, Elviss Dvinskis, Elena Manakova, Saulius Gražulis, Kaspars Tars & Daumantas Matulis. (2020) Halogenated and di-substituted benzenesulfonamides as selective inhibitors of carbonic anhydrase isoforms. European Journal of Medicinal Chemistry 185, pages 111825.
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Soumajit Ghorai, Sravani Pulya, Kalyan Ghosh, Parthasarathi Panda, Balaram Ghosh & Shovanlal Gayen. (2020) Structure-activity relationship of human carbonic anhydrase-II inhibitors: Detailed insight for future development as anti-glaucoma agents. Bioorganic Chemistry 95, pages 103557.
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Noureddine Boucif, Denis Roizard & Eric Favre. 2020. Membranes for Environmental Applications. Membranes for Environmental Applications
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Alessio Nocentini, Sameh M. Osman, Sonia Del Prete, Clemente Capasso, Zeid A. ALOthman & Claudiu T. Supuran. (2019) Extending the γ-class carbonic anhydrases inhibition profiles with phenolic compounds. Bioorganic Chemistry 93, pages 103336.
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Adel S. El-Azab, Alaa A.-M. Abdel-Aziz, Silvia Bua, Alessio Nocentini, Nawaf A. AlSaif, Abdulrahman A. Almehizia, Mohammed M. Alanazi, Mohamed M. Hefnawy & Claudiu T. Supuran. (2019) New anthranilic acid-incorporating N-benzenesulfonamidophthalimides as potent inhibitors of carbonic anhydrases I, II, IX, and XII: Synthesis, in vitro testing, and in silico assessment. European Journal of Medicinal Chemistry 181, pages 111573.
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K. Koruza, B. Lafumat, M. Nyblom, B. P. Mahon, W. Knecht, R. McKenna & S. Z. Fisher. (2019) Structural comparison of protiated, H/D-exchanged and deuterated human carbonic anhydrase IX. Acta Crystallographica Section D Structural Biology 75:10, pages 895-903.
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Begüm Nurpelin Sağlık, Ulviye Acar Çevik, Derya Osmaniye, Serkan Levent, Betul Kaya Çavuşoğlu, Yeliz Demir, Sinem Ilgın, Yusuf Özkay, Ali Savaş Koparal, Şükrü Beydemir & Zafer Asım Kaplancıklı. (2019) Synthesis, molecular docking analysis and carbonic anhydrase I-II inhibitory evaluation of new sulfonamide derivatives. Bioorganic Chemistry 91, pages 103153.
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Vahideh Asadi, Reihaneh Kardanpour, Shahram Tangestaninejad, Majid Moghadam, Valiollah Mirkhani & Iraj Mohammadpoor-Baltork. (2019)
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Justina Kazokaitė, Visvaldas Kairys, Joana Smirnovienė, Alexey Smirnov, Elena Manakova, Martti Tolvanen, Seppo Parkkila & Daumantas Matulis. (2019) Engineered Carbonic Anhydrase VI-Mimic Enzyme Switched the Structure and Affinities of Inhibitors. Scientific Reports 9:1.
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Bani Kaur Suri, Artur Schmidtchen & Navin Kumar Verma. (2019)
Carbonic anhydrases in human keratinocytes and their regulation by all‐
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Wagdy M. Eldehna, Mahmoud F. Abo-Ashour, Emanuela Berrino, Daniela Vullo, Hazem A. Ghabbour, Sara T. Al-Rashood, Ghada S. Hassan, Hamad M. Alkahtani, Abdulrahman A. Almehizia, Amal Alharbi, Hatem A. Abdel-Aziz & Claudiu T. Supuran. (2019) SLC-0111 enaminone analogs, 3/4-(3-aryl-3-oxopropenyl) aminobenzenesulfonamides, as novel selective subnanomolar inhibitors of the tumor-associated carbonic anhydrase isoform IX. Bioorganic Chemistry 83, pages 549-558.
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Irena Vaškevičienė, Vaida Paketurytė, Nikita Pajanok, Šarūnas Žukauskas, Birutė Sapijanskaitė, Kristina Kantminienė, Vytautas Mickevičius, Asta Zubrienė & Daumantas Matulis. (2019) Pyrrolidinone-bearing methylated and halogenated benzenesulfonamides as inhibitors of carbonic anhydrases. Bioorganic & Medicinal Chemistry 27:2, pages 322-337.
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Akilah B. Murray, Mayank Aggarwal, Melissa Pinard, Daniela Vullo, Marianna Patrauchan, Claudiu T. Supuran & Robert McKenna. (2018)
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Audrius Zakšauskas, Edita Čapkauskaitė, Linas Jezepčikas, Vaida Linkuvienė, Miglė Kišonaitė, Alexey Smirnov, Elena Manakova, Saulius Gražulis & Daumantas Matulis. (2018) Design of two-tail compounds with rotationally fixed benzenesulfonamide ring as inhibitors of carbonic anhydrases. European Journal of Medicinal Chemistry 156, pages 61-78.
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Martina Buonanno, Anna Di Fiore, Emma Langella, Katia D’Ambrosio, Claudiu Supuran, Simona Monti & Giuseppina De Simone. (2018) The Crystal Structure of a hCA VII Variant Provides Insights into the Molecular Determinants Responsible for Its Catalytic Behavior. International Journal of Molecular Sciences 19:6, pages 1571.
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Chandra Bhushan Mishra, Shikha Kumari, Andrea Angeli, Silvia Bua, Manisha Tiwari & Claudiu T. Supuran. (2018) Discovery of Benzenesulfonamide Derivatives as Carbonic Anhydrase Inhibitors with Effective Anticonvulsant Action: Design, Synthesis, and Pharmacological Evaluation. Journal of Medicinal Chemistry 61:7, pages 3151-3165.
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Edita Čapkauskaitė, Asta Zubrienė, Vaida Paketurytė, David D. Timm, Sigitas Tumkevičius & Daumantas Matulis. (2018) Thiazole-substituted benzenesulfonamides as inhibitors of 12 human carbonic anhydrases. Bioorganic Chemistry 77, pages 534-541.
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Sirous Ghobadi, Mohammad Reza Ashrafi-Kooshk, Hamid Mahdiuni & Reza Khodarahmi. (2018) Enhancement of intrinsic fluorescence of human carbonic anhydrase II upon topiramate binding: Some evidence for drug-induced molecular contraction of the protein. International Journal of Biological Macromolecules 108, pages 240-249.
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Edita Čapkauskaitė, Audrius Zakšauskas, Virginijus Ruibys, Vaida Linkuvienė, Vaida Paketurytė, Marius Gedgaudas, Visvaldas Kairys & Daumantas Matulis. (2018) Benzimidazole design, synthesis, and docking to build selective carbonic anhydrase VA inhibitors. Bioorganic & Medicinal Chemistry 26:3, pages 675-687.
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Kanij Rukshana Sumi, Soo Cheol Kim, Sathishkumar Natarajan, Kap Seong Choi, Myeong Rak Choi, Hoy-Taek Kim, Jong-In Park, Ill-Sup Nou, Kathleen M. Gilmour & Kang Hee Kho. (2018) Molecular cloning and characterization of secretory carbonic anhydrase VI in pufferfish ( Takifugu rubripes ). Gene 640, pages 57-65.
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Laura De Luca, Francesca Mancuso, Stefania Ferro, Maria Rosa Buemi, Andrea Angeli, Sonia Del Prete, Clemente Capasso, Claudiu T. Supuran & Rosaria Gitto. (2018) Inhibitory effects and structural insights for a novel series of coumarin-based compounds that selectively target human CA IX and CA XII carbonic anhydrases. European Journal of Medicinal Chemistry 143, pages 276-282.
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Justina Kazokaitė, Ashok Aspatwar, Seppo Parkkila & Daumantas Matulis. (2017) An update on anticancer drug development and delivery targeting carbonic anhydrase IX. PeerJ 5, pages e4068.
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Srinivas Angapelly, P.V. Sri Ramya, Andrea Angeli, Sonia Del Prete, Clemente Capasso, Mohammed Arifuddin & Claudiu T. Supuran. (2017) Development of sulfonamides incorporating phenylacrylamido functionalities as carbonic anhydrase isoforms I, II, IX and XII inhibitors. Bioorganic & Medicinal Chemistry 25:20, pages 5726-5732.
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Andrea Angeli, Alaa A.-M. Abdel-Aziz, Alessio Nocentini, Adel S. El-Azab, Paola Gratteri & Claudiu T. Supuran. (2017) Synthesis and carbonic anhydrase inhibition of polycyclic imides incorporating N-benzenesulfonamide moieties. Bioorganic & Medicinal Chemistry 25:20, pages 5373-5379.
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Claudiu T. Supuran. (2017) Bortezomib inhibits mammalian carbonic anhydrases. Bioorganic & Medicinal Chemistry 25:19, pages 5064-5067.
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Paolo Piazzetta, Tiziana Marino, Nino Russo & Dennis R. Salahub. (2017) The role of metal substitution in the promiscuity of natural and artificial carbonic anhydrases. Coordination Chemistry Reviews 345, pages 73-85.
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Lina Baranauskiene & Daumantas Matulis. (2017)
Herbicide oryzalin inhibits human carbonic anhydrases
in vitro
. Journal of Biochemical and Molecular Toxicology 31:6, pages e21894.
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Zhuang Hou, Bin Lin, Yu Bao, Hai-ning Yan, Miao Zhang, Xiao-wei Chang, Xin-xin Zhang, Zi-jie Wang, Gao-fei Wei, Mao-sheng Cheng, Yang Liu & Chun Guo. (2017) Dual-tail approach to discovery of novel carbonic anhydrase IX inhibitors by simultaneously matching the hydrophobic and hydrophilic halves of the active site. European Journal of Medicinal Chemistry 132, pages 1-10.
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Fabrizio Carta, Alexander Birkmann, Tamara Pfaff, Helmut Buschmann, Wilfried Schwab, Holger Zimmermann, Alfonso Maresca & Claudiu T. Supuran. (2017) Lead Development of Thiazolylsulfonamides with Carbonic Anhydrase Inhibitory Action. Journal of Medicinal Chemistry 60:7, pages 3154-3164.
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Chandra Bhushan Mishra, Shikha Kumari, Andrea Angeli, Simona Maria Monti, Martina Buonanno, Manisha Tiwari & Claudiu T. Supuran. (2017) Discovery of Benzenesulfonamides with Potent Human Carbonic Anhydrase Inhibitory and Effective Anticonvulsant Action: Design, Synthesis, and Pharmacological Assessment. Journal of Medicinal Chemistry 60:6, pages 2456-2469.
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Jekaterīna Ivanova, Agnese Balode, Raivis Žalubovskis, Janis Leitans, Andris Kazaks, Daniela Vullo, Kaspars Tars & Claudiu T. Supuran. (2017) 5-Substituted-benzylsulfanyl-thiophene-2-sulfonamides with effective carbonic anhydrase inhibitory activity: Solution and crystallographic investigations. Bioorganic & Medicinal Chemistry 25:3, pages 857-863.
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Avni Bhatt, Brian P. Mahon, Vinicius Wilian D. Cruzeiro, Benedetta Cornelio, Marie Laronze-Cochard, Mariangela Ceruso, Janos Sapi, Graham A. Rance, Andrei N. Khlobystov, Antonella Fontana, Adrian Roitberg, Claudiu T. Supuran & Robert McKenna. (2017) Structure-Activity Relationships of Benzenesulfonamide-Based Inhibitors towards Carbonic Anhydrase Isoform Specificity. ChemBioChem 18:2, pages 213-222.
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Daniela Vullo, Sonia Del Prete, Sameh M. Osman, Zeid AlOthman, Clemente Capasso, William A. Donald & Claudiu T. Supuran. (2017) Burkholderia pseudomallei γ-carbonic anhydrase is strongly activated by amino acids and amines. Bioorganic & Medicinal Chemistry Letters 27:1, pages 77-80.
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Murat Bozdag, Ahmed Mahmoud Alafeefy, Abdul Malik Altamimi, Daniela Vullo, Fabrizio Carta & Claudiu T. Supuran. (2017) Coumarins and other fused bicyclic heterocycles with selective tumor-associated carbonic anhydrase isoforms inhibitory activity. Bioorganic & Medicinal Chemistry 25:2, pages 677-683.
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Xiaohong Wang, Meik Neufurth, Emad Tolba, Shunfeng Wang, Heinz C. Schröder & Werner E. G. Müller. 2017. Blue Biotechnology. Blue Biotechnology
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257
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Alessio Nocentini, Marta Ferraroni, Fabrizio Carta, Mariangela Ceruso, Paola Gratteri, Cecilia Lanzi, Emanuela Masini & Claudiu T. Supuran. (2016) Benzenesulfonamides Incorporating Flexible Triazole Moieties Are Highly Effective Carbonic Anhydrase Inhibitors: Synthesis and Kinetic, Crystallographic, Computational, and Intraocular Pressure Lowering Investigations. Journal of Medicinal Chemistry 59:23, pages 10692-10704.
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Habiba Bouzit, Maamar Stiti & Mohamed Abdaoui. (2016) Spectroscopic and molecular modelling investigations of supramolecular complex of β-cyclodextrin with N-[(4-sulfonamidophenyl)ethyl]-5-(1,2-dithiolan-3-yl)pentanamide. Journal of Inclusion Phenomena and Macrocyclic Chemistry 86:1-2, pages 121-134.
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Claudiu T. Supuran. (2016) Bortezomib inhibits bacterial and fungal β-carbonic anhydrases. Bioorganic & Medicinal Chemistry 24:18, pages 4406-4409.
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Murat Bozdag, Ahmed M. Alafeefy, Fabrizio Carta, Mariangela Ceruso, Abdul-Malek S. Al-Tamimi, Abdulla A. Al-Kahtani, Fatmah A.S. Alasmary & Claudiu T. Supuran. (2016) Synthesis 4-[2-(2-mercapto-4-oxo-4H-quinazolin-3-yl)-ethyl]-benzenesulfonamides with subnanomolar carbonic anhydrase II and XII inhibitory properties. Bioorganic & Medicinal Chemistry 24:18, pages 4100-4107.
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Kanij Rukshana Sumi, Ill-Sup Nou & Kang Hee Kho. (2016) Identification and expression of a novel carbonic anhydrase isozyme in the pufferfish Takifugu vermicularis. Gene 588:2, pages 173-179.
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Daniela Vullo, Claudiu T. Supuran, Andrea Scozzafava, Giuseppina De Simone, Simona Maria Monti, Vincenzo Alterio & Fabrizio Carta. (2016) Kinetic and X-ray crystallographic investigations of substituted 2-thio-6-oxo-1,6-dihydropyrimidine–benzenesulfonamides acting as carbonic anhydrase inhibitors. Bioorganic & Medicinal Chemistry 24:16, pages 3643-3648.
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Alessio Nocentini, Daniela Vullo, Gianluca Bartolucci & Claudiu T. Supuran. (2016) N-Nitrosulfonamides: A new chemotype for carbonic anhydrase inhibition. Bioorganic & Medicinal Chemistry 24:16, pages 3612-3617.
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Claudiu T. Supuran. (2016) Structure and function of carbonic anhydrases. Biochemical Journal 473:14, pages 2023-2032.
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Daniela Vullo, Mariaconcetta Durante, Francesco Saverio Di Leva, Sandro Cosconati, Emanuela Masini, Andrea Scozzafava, Ettore Novellino, Claudiu T. Supuran & Fabrizio Carta. (2016) Monothiocarbamates Strongly Inhibit Carbonic Anhydrases in Vitro and Possess Intraocular Pressure Lowering Activity in an Animal Model of Glaucoma. Journal of Medicinal Chemistry 59:12, pages 5857-5867.
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Vladimir O. Talibov, Vaida Linkuvienė, Daumantas Matulis & U. Helena Danielson. (2016) Kinetically Selective Inhibitors of Human Carbonic Anhydrase Isozymes I, II, VII, IX, XII, and XIII. Journal of Medicinal Chemistry 59:5, pages 2083-2093.
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Ahmed M. Alafeefy, Fabrizio Carta, Mariangela Ceruso, Abdul-Malek S. Al-Tamimi, Abdulla A. Al-Kahtani & Claudiu T. Supuran. (2016) Development of 3-(4-aminosulphonyl)-phenyl-2-mercapto-3H-quinazolin-4-ones as inhibitors of carbonic anhydrase isoforms involved in tumorigenesis and glaucoma. Bioorganic & Medicinal Chemistry 24:6, pages 1402-1407.
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Carrie L. Lomelino, Brian P. Mahon, Robert McKenna, Fabrizio Carta & Claudiu T. Supuran. (2016) Kinetic and X-ray crystallographic investigations on carbonic anhydrase isoforms I, II, IX and XII of a thioureido analog of SLC-0111. Bioorganic & Medicinal Chemistry 24:5, pages 976-981.
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Aistė Kasiliauskaitė, Vida Časaitė, Vaida Juozapaitienė, Asta Zubrienė, Vilma Michailovienė, Jurgita Revuckienė, Lina Baranauskienė, Rolandas Meškys & Daumantas Matulis. (2015) Thermodynamic characterization of human carbonic anhydrase VB stability and intrinsic binding of compounds. Journal of Thermal Analysis and Calorimetry 123:3, pages 2191-2200.
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Elisabetta Barresi, Silvia Salerno, Anna Maria Marini, Sabrina Taliani, Concettina La Motta, Francesca Simorini, Federico Da Settimo, Daniela Vullo & Claudiu T. Supuran. (2016) Sulfonamides incorporating heteropolycyclic scaffolds show potent inhibitory action against carbonic anhydrase isoforms I, II, IX and XII. Bioorganic & Medicinal Chemistry 24:4, pages 921-927.
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Benedetta Cornelio, Marie Laronze-Cochard, Mariangela Ceruso, Marta Ferraroni, Graham A. RanceFabrizio Carta, Andrei N. KhlobystovAntonella Fontana, Claudiu T. Supuran & Janos Sapi. (2016) 4-Arylbenzenesulfonamides as Human Carbonic Anhydrase Inhibitors (hCAIs): Synthesis by Pd Nanocatalyst-Mediated Suzuki–Miyaura Reaction, Enzyme Inhibition, and X-ray Crystallographic Studies. Journal of Medicinal Chemistry 59:2, pages 721-732.
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Marta Ferraroni, Fabrizio Carta, Andrea Scozzafava & Claudiu T. Supuran. (2015) Thioxocoumarins Show an Alternative Carbonic Anhydrase Inhibition Mechanism Compared to Coumarins. Journal of Medicinal Chemistry 59:1, pages 462-473.
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Werner E. G. Müller, Heinz C. Schröder, Emad Tolba, Bärbel Diehl-Seifert & Xiaohong Wang. (2016) Mineralization of bone-related SaOS-2 cells under physiological hypoxic conditions. FEBS Journal 283:1, pages 74-87.
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Adel S. El-Azab, Alaa A.-M. Abdel-Aziz, Rezk R. Ayyad, Mariangela Ceruso & Claudiu T. Supuran. (2016) Inhibition of carbonic anhydrase isoforms I, II, IV, VII and XII with carboxylates and sulfonamides incorporating phthalimide/phthalic anhydride scaffolds. Bioorganic & Medicinal Chemistry 24:1, pages 20-25.
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Fabrizio Carta, Marta Ferraroni, Andrea Scozzafava & Claudiu T. Supuran. (2016) Fluorescent sulfonamide carbonic anhydrase inhibitors incorporating 1,2,3-triazole moieties: Kinetic and X-ray crystallographic studies. Bioorganic & Medicinal Chemistry 24:2, pages 104-112.
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Xiaohong Wang, Heinz C. Schröder & Werner E. G. Müller. (2015) Polyphosphate as a metabolic fuel in Metazoa: A foundational breakthrough invention for biomedical applications. Biotechnology Journal 11:1, pages 11-30.
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Marta Ferraroni, Sonia Del Prete, Daniela Vullo, Clemente Capasso & Claudiu T. Supuran. (2015)
Crystal structure and kinetic studies of a tetrameric type II β-carbonic anhydrase from the pathogenic bacterium
Vibrio cholerae
. Acta Crystallographica Section D Biological Crystallography 71:12, pages 2449-2456.
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Murat Bozdag, Ahmed M. Alafeefy, Daniela Vullo, Fabrizio Carta, Nurcan Dedeoglu, Abdul-Malek S. Al-Tamimi, Nabila A. Al-Jaber, Andrea Scozzafava & Claudiu T. Supuran. (2015) Benzenesulfonamides incorporating bulky aromatic/heterocyclic tails with potent carbonic anhydrase inhibitory activity. Bioorganic & Medicinal Chemistry 23:24, pages 7751-7764.
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Giuseppe La Regina, Antonio Coluccia, Valeria Famiglini, Sveva Pelliccia, Ludovica Monti, Daniela Vullo, Elisa Nuti, Vincenzo Alterio, Giuseppina De Simone, Simona Maria Monti, Peiwen Pan, Seppo Parkkila, Claudiu T. Supuran, Armando Rossello & Romano Silvestri. (2015) Discovery of 1,1′-Biphenyl-4-sulfonamides as a New Class of Potent and Selective Carbonic Anhydrase XIV Inhibitors. Journal of Medicinal Chemistry 58:21, pages 8564-8572.
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Mayank Aggarwal, Teck Khiang Chua, Melissa A. Pinard, Doletha M. Szebenyi & Robert McKenna. (2015) Carbon Dioxide “Trapped” in a β-Carbonic Anhydrase. Biochemistry 54:43, pages 6631-6638.
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Viviana De Luca, Sonia Del Prete, Vincenzo Carginale, Daniela Vullo, Claudiu T. Supuran & Clemente Capasso. (2015) Cloning, characterization and anion inhibition studies of a γ-carbonic anhydrase from the Antarctic cyanobacterium Nostoc commune. Bioorganic & Medicinal Chemistry Letters 25:21, pages 4970-4975.
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Alessio Nocentini, Fabrizio Carta, Mariangela Ceruso, Gianluca Bartolucci & Claudiu T. Supuran. (2015) Click-tailed coumarins with potent and selective inhibitory action against the tumor-associated carbonic anhydrases IX and XII. Bioorganic & Medicinal Chemistry 23:21, pages 6955-6966.
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Melissa A. Pinard, Mayank Aggarwal, Brian P. Mahon, Chingkuang Tu & Robert McKenna. (2015) A sucrose-binding site provides a lead towards an isoform-specific inhibitor of the cancer-associated enzyme carbonic anhydrase IX. Acta Crystallographica Section F Structural Biology Communications 71:10, pages 1352-1358.
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Hany S. Ibrahim, Sahar M. Abou-Seri, Muhammet Tanc, Mahmoud M. Elaasser, Hatem A. Abdel-Aziz & Claudiu T. Supuran. (2015) Isatin-pyrazole benzenesulfonamide hybrids potently inhibit tumor-associated carbonic anhydrase isoforms IX and XII. European Journal of Medicinal Chemistry 103, pages 583-593.
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Asta Zubrienė, Joana Smirnovienė, Alexey Smirnov, Vaida Morkūnaitė, Vilma Michailovienė, Jelena Jachno, Vaida Juozapaitienė, Povilas Norvaišas, Elena Manakova, Saulius Gražulis & Daumantas Matulis. (2015) Intrinsic thermodynamics of 4-substituted-2,3,5,6-tetrafluorobenzenesulfonamide binding to carbonic anhydrases by isothermal titration calorimetry. Biophysical Chemistry 205, pages 51-65.
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İbrahim Esirden, Ramazan Ulus, Burak Aday, Muhammet Tanç, Claudiu T. Supuran & Muharrem Kaya. (2015) Synthesis of novel acridine bis-sulfonamides with effective inhibitory activity against the carbonic anhydrase isoforms I, II, IX and XII. Bioorganic & Medicinal Chemistry 23:20, pages 6573-6580.
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Mariangela Ceruso, Fabrizio Carta, Sameh M. Osman, Zeid Alothman, Simona Maria Monti & Claudiu T. Supuran. (2015) Inhibition studies of bacterial, fungal and protozoan β-class carbonic anhydrases with Schiff bases incorporating sulfonamide moieties. Bioorganic & Medicinal Chemistry 23:15, pages 4181-4187.
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Melissa A. Pinard, Shalaka R. Lotlikar, Christopher D. Boone, Daniela Vullo, Claudiu T. Supuran, Marianna A. Patrauchan & Robert McKenna. (2015) Structure and inhibition studies of a type II beta-carbonic anhydrase psCA3 from Pseudomonas aeruginosa. Bioorganic & Medicinal Chemistry 23:15, pages 4831-4838.
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Diaa A. Ibrahim, Deena S. Lasheen, Maysoun Y. Zaky, Amany W. Ibrahim, Daniela Vullo, Mariangela Ceruso, Claudiu T. Supuran & Dalal A. Abou El Ella. (2015) Design and synthesis of benzothiazole-6-sulfonamides acting as highly potent inhibitors of carbonic anhydrase isoforms I, II, IX and XII. Bioorganic & Medicinal Chemistry 23:15, pages 4989-4999.
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Aiga Grandane, Muhammet Tanc, Lorenzo Di Cesare Mannelli, Fabrizio Carta, Carla Ghelardini, Raivis Žalubovskis & Claudiu T. Supuran. (2015) 6-Substituted Sulfocoumarins Are Selective Carbonic Anhdydrase IX and XII Inhibitors with Significant Cytotoxicity against Colorectal Cancer Cells. Journal of Medicinal Chemistry 58:9, pages 3975-3983.
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Leo Syrjänen, Marianne Kuuslahti, Martti Tolvanen, Daniela Vullo, Seppo Parkkila & Claudiu T. Supuran. (2015) The β-carbonic anhydrase from the malaria mosquito Anopheles gambiae is highly inhibited by sulfonamides. Bioorganic & Medicinal Chemistry 23:10, pages 2303-2309.
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Murat Bozdag, Fabrizio Carta, Daniela Vullo, Atilla Akdemir, Semra Isik, Cecilia Lanzi, Andrea Scozzafava, Emanuela Masini & Claudiu T. Supuran. (2015) Synthesis of a new series of dithiocarbamates with effective human carbonic anhydrase inhibitory activity and antiglaucoma action. Bioorganic & Medicinal Chemistry 23:10, pages 2368-2376.
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Christopher D. Boone, Valerio Rasi, Chingkuang Tu & Robert McKenna. (2015) Structural and catalytic effects of proline substitution and surface loop deletion in the extended active site of human carbonic anhydrase II. FEBS Journal 282:8, pages 1445-1457.
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Daniela Vullo, Viviana De Luca, Sonia Del Prete, Vincenzo Carginale, Andrea Scozzafava, Clemente Capasso & Claudiu T. Supuran. (2015) Sulfonamide inhibition studies of the γ-carbonic anhydrase from the Antarctic cyanobacterium Nostoc commune. Bioorganic & Medicinal Chemistry 23:8, pages 1728-1734.
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Fabrizio Carta, Lorenzo Di Cesare Mannelli, Melissa Pinard, Carla Ghelardini, Andrea Scozzafava, Robert McKenna & Claudiu T. Supuran. (2015) A class of sulfonamide carbonic anhydrase inhibitors with neuropathic pain modulating effects. Bioorganic & Medicinal Chemistry 23:8, pages 1828-1840.
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Virginija Dudutienė, Asta Zubrienė, Alexey Smirnov, David D. Timm, Joana Smirnovienė, Justina Kazokaitė, Vilma Michailovienė, Audrius Zakšauskas, Elena Manakova, Saulius Gražulis & Daumantas Matulis. (2015) Functionalization of Fluorinated Benzenesulfonamides and Their Inhibitory Properties toward Carbonic Anhydrases. ChemMedChem 10:4, pages 662-687.
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Muhammet Tanc, Fabrizio Carta, Andrea Scozzafava & Claudiu T. Supuran. (2015) α-Carbonic Anhydrases Possess Thioesterase Activity. ACS Medicinal Chemistry Letters 6:3, pages 292-295.
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Rajendra P. Tanpure, Bin Ren, Thomas S. Peat, Laurent F. Bornaghi, Daniela Vullo, Claudiu T. Supuran & Sally-Ann Poulsen. (2015) Carbonic Anhydrase Inhibitors with Dual-Tail Moieties To Match the Hydrophobic and Hydrophilic Halves of the Carbonic Anhydrase Active Site. Journal of Medicinal Chemistry 58:3, pages 1494-1501.
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Brian P. Mahon, Alex M. Hendon, Jenna M. Driscoll, Gregory M. Rankin, Sally-Ann Poulsen, Claudiu T. Supuran & Robert McKenna. (2015) Saccharin: A lead compound for structure-based drug design of carbonic anhydrase IX inhibitors. Bioorganic & Medicinal Chemistry 23:4, pages 849-854.
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Brian Mahon, Melissa Pinard & Robert McKenna. (2015) Targeting Carbonic Anhydrase IX Activity and Expression. Molecules 20:2, pages 2323-2348.
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Murat Boztaş, Yasin Çetinkaya, Meryem Topal, İlhami Gülçin, Abdullah Menzek, Ertan Şahin, Muhammet Tanc & Claudiu T. Supuran. (2014) Synthesis and Carbonic Anhydrase Isoenzymes I, II, IX, and XII Inhibitory Effects of Dimethoxybromophenol Derivatives Incorporating Cyclopropane Moieties. Journal of Medicinal Chemistry 58:2, pages 640-650.
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Melissa A. Pinard, Brian Mahon & Robert McKenna. (2015) Probing the Surface of Human Carbonic Anhydrase for Clues towards the Design of Isoform Specific Inhibitors. BioMed Research International 2015, pages 1-15.
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V. Alterio, M. Tanc, J. Ivanova, R. Zalubovskis, I. Vozny, S. M. Monti, A. Di Fiore, G. De Simone & C. T. Supuran. (2015) X-ray crystallographic and kinetic investigations of 6-sulfamoyl-saccharin as a carbonic anhydrase inhibitor. Organic & Biomolecular Chemistry 13:13, pages 4064-4069.
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Muhammet Tanc, Fabrizio Carta, Andrea Scozzafava & Claudiu T. Supuran. (2015) 6-Substituted 1,2-benzoxathiine-2,2-dioxides are isoform-selective inhibitors of human carbonic anhydrases IX, XII and VA. Organic & Biomolecular Chemistry 13:1, pages 77-80.
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Simona M. Monti, Giuseppina De Simone, Claudiu T. Supuran & Vincenzo Alterio. 2015. Carbonic Anhydrases as Biocatalysts. Carbonic Anhydrases as Biocatalysts
351
359
.
Christopher D. Boone & Robert McKenna. 2015. Carbonic Anhydrases as Biocatalysts. Carbonic Anhydrases as Biocatalysts
291
309
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Claudiu T. Supuran, Clemente Capasso & Giuseppina De Simone. 2015. Carbonic Anhydrases as Biocatalysts. Carbonic Anhydrases as Biocatalysts
51
90
.
Nicolino Pala, Roberta Cadoni & Mario Sechi. 2015. Carbonic Anhydrases as Biocatalysts. Carbonic Anhydrases as Biocatalysts
31
49
.
Miglė Kišonaitė, Asta Zubrienė, Edita Čapkauskaitė, Alexey Smirnov, Joana Smirnovienė, Visvaldas Kairys, Vilma Michailovienė, Elena Manakova, Saulius Gražulis & Daumantas Matulis. (2014) Intrinsic Thermodynamics and Structure Correlation of Benzenesulfonamides with a Pyrimidine Moiety Binding to Carbonic Anhydrases I, II, VII, XII, and XIII. PLoS ONE 9:12, pages e114106.
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Mariangela Ceruso, Sabrina Antel, Daniela Vullo, Andrea Scozzafava & Claudiu T. Supuran. (2014) Inhibition studies of new ureido-substituted sulfonamides incorporating a GABA moiety against human carbonic anhydrase isoforms I–XIV. Bioorganic & Medicinal Chemistry 22:24, pages 6768-6775.
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Murat Bozdag, Melissa Pinard, Fabrizio Carta, Emanuela Masini, Andrea Scozzafava, Robert McKenna & Claudiu T. Supuran. (2014) A Class of 4-Sulfamoylphenyl-ω-aminoalkyl Ethers with Effective Carbonic Anhydrase Inhibitory Action and Antiglaucoma Effects. Journal of Medicinal Chemistry 57:22, pages 9673-9686.
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Virginija Dudutienė, Jurgita Matulienė, Alexey Smirnov, David D. Timm, Asta Zubrienė, Lina Baranauskienė, Vaida Morku̅naitė, Joana Smirnovienė, Vilma Michailovienė, Vaida Juozapaitienė, Aurelija Mickevičiu̅tė, Justina Kazokaitė, Sandra Bakšytė, Aistė Kasiliauskaitė, Jelena Jachno, Jurgita Revuckienė, Miglė Kišonaitė, Vilma Pilipuitytė, Eglė Ivanauskaitė, Goda Milinavičiu̅tė, Vytautas Smirnovas, Vilma Petrikaitė, Visvaldas Kairys, Vytautas Petrauskas, Povilas Norvaišas, Darius Lingė, Paulius Gibieža, Edita Čapkauskaitė, Audrius Zakšauskas, Egidijus Kazlauskas, Elena Manakova, Saulius Gražulis, John E. Ladbury & Daumantas Matulis. (2014) Discovery and Characterization of Novel Selective Inhibitors of Carbonic Anhydrase IX. Journal of Medicinal Chemistry 57:22, pages 9435-9446.
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Murat Bozdag, Marta Ferraroni, Fabrizio Carta, Daniela Vullo, Laura Lucarini, Elisabetta Orlandini, Armando Rossello, Elisa Nuti, Andrea Scozzafava, Emanuela Masini & Claudiu T. Supuran. (2014) Structural Insights on Carbonic Anhydrase Inhibitory Action, Isoform Selectivity, and Potency of Sulfonamides and Coumarins Incorporating Arylsulfonylureido Groups. Journal of Medicinal Chemistry 57:21, pages 9152-9167.
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Alaa A.-M. Abdel-Aziz, Adel S. El-Azab, Mariangela Ceruso & Claudiu T. Supuran. (2014) Carbonic anhydrase inhibitory activity of sulfonamides and carboxylic acids incorporating cyclic imide scaffolds. Bioorganic & Medicinal Chemistry Letters 24:22, pages 5185-5189.
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Kęstutis Rutkauskas, Asta Zubrienė, Ingrida Tumosienė, Kristina Kantminienė, Marytė Kažemėkaitė, Alexey Smirnov, Justina Kazokaitė, Vaida Morkūnaitė, Edita Čapkauskaitė, Elena Manakova, Saulius Gražulis, Zigmuntas Beresnevičius & Daumantas Matulis. (2014) 4-Amino-substituted Benzenesulfonamides as Inhibitors of Human Carbonic Anhydrases. Molecules 19:11, pages 17356-17380.
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Mariangela Ceruso, Sonia Del Prete, Zeid AlOthman, Sameh M. Osman, Andrea Scozzafava, Clemente Capasso & Claudiu T. Supuran. (2014) Synthesis of sulfonamides with effective inhibitory action against Porphyromonas gingivalis γ-carbonic anhydrase. Bioorganic & Medicinal Chemistry Letters 24:16, pages 4006-4010.
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Leo Syrjänen, Seppo Parkkila, Andrea Scozzafava & Claudiu T. Supuran. (2014) Sulfonamide inhibition studies of the β carbonic anhydrase from Drosophila melanogaster. Bioorganic & Medicinal Chemistry Letters 24:13, pages 2797-2801.
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Mostafa M. Ghorab, Mansour S. Alsaid, Mariangela Ceruso, Yassin M. Nissan & Claudiu T. Supuran. (2014) Carbonic anhydrase inhibitors: Synthesis, molecular docking, cytotoxic and inhibition of the human carbonic anhydrase isoforms I, II, IX, XII with novel benzenesulfonamides incorporating pyrrole, pyrrolopyrimidine and fused pyrrolopyrimidine moieties. Bioorganic & Medicinal Chemistry 22:14, pages 3684-3695.
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Aiga Grandane, Muhammet Tanc, Raivis Zalubovskis & Claudiu T. Supuran. (2014) Synthesis of 6-tetrazolyl-substituted sulfocoumarins acting as highly potent and selective inhibitors of the tumor-associated carbonic anhydrase isoforms IX and XII. Bioorganic & Medicinal Chemistry 22:5, pages 1522-1528.
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Eoin P. Cummins, Andrew C. Selfridge, Peter H. Sporn, Jacob I. Sznajder & Cormac T. Taylor. (2013) Carbon dioxide-sensing in organisms and its implications for human disease. Cellular and Molecular Life Sciences 71:5, pages 831-845.
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Daniela Vullo, Sonia Del Prete, Sameh M. Osman, Viviana De Luca, Andrea Scozzafava, Zeid AlOthman, Claudiu T. Supuran & Clemente Capasso. (2014) Sulfonamide inhibition studies of the γ-carbonic anhydrase from the oral pathogen Porphyromonas gingivalis. Bioorganic & Medicinal Chemistry Letters 24:1, pages 240-244.
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Ahmed M. Alafeefy, Hatem A. Abdel-Aziz, Daniela Vullo, Abdul-Malek S. Al-Tamimi, Nabila A. Al-Jaber, Clemente Capasso & Claudiu T. Supuran. (2014) Inhibition of carbonic anhydrases from the extremophilic bacteria Sulfurihydrogenibium yellostonense (SspCA) and S. azorense (SazCA) with a new series of sulfonamides incorporating aroylhydrazone-, [1,2,4]triazolo[3,4-b][1,3,4]thiadiazinyl- or 2-(cyanophenylmethylene)-1,3,4-thiadiazol-3(2H)-yl moieties. Bioorganic & Medicinal Chemistry 22:1, pages 141-147.
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Murat Bozdag, Marta Ferraroni, Elisa Nuti, Daniela Vullo, Armando Rossello, Fabrizio Carta, Andrea Scozzafava & Claudiu T. Supuran. (2014) Combining the tail and the ring approaches for obtaining potent and isoform-selective carbonic anhydrase inhibitors: Solution and X-ray crystallographic studies. Bioorganic & Medicinal Chemistry 22:1, pages 334-340.
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Christopher D. Boone, Melissa Pinard, Rob McKenna & David Silverman. 2014. Carbonic Anhydrase: Mechanism, Regulation, Links to Disease, and Industrial Applications. Carbonic Anhydrase: Mechanism, Regulation, Links to Disease, and Industrial Applications
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Mariangela Ceruso, Daniela Vullo, Andrea Scozzafava & Claudiu T. Supuran. (2013) Inhibition of human carbonic anhydrase isoforms I–XIV with sulfonamides incorporating fluorine and 1,3,5-triazine moieties. Bioorganic & Medicinal Chemistry 21:22, pages 6929-6936.
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Özlen Güzel-Akdemir, Shyamasri Biswas, Katherine Lastra, Robert McKenna & Claudiu T. Supuran. (2013) Structural study of the location of the phenyl tail of benzene sulfonamides and the effect on human carbonic anhydrase inhibition. Bioorganic & Medicinal Chemistry 21:21, pages 6674-6680.
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Christopher D. Boone, Sonika Gill, Chingkuang Tu, David N. Silverman & Robert McKenna. (2013) Structural, catalytic and stabilizing consequences of aromatic cluster variants in human carbonic anhydrase II. Archives of Biochemistry and Biophysics 539:1, pages 31-37.
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Shyamasri Biswas, Robert McKenna & Claudiu T. Supuran. (2013) Effect of incorporating a thiophene tail in the scaffold of acetazolamide on the inhibition of human carbonic anhydrase isoforms I, II, IX and XII. Bioorganic & Medicinal Chemistry Letters 23:20, pages 5646-5649.
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Leo Syrjänen, Alane Beatriz Vermelho, Igor de Almeida Rodrigues, Suzana Corte-Real, Terhi Salonen, Peiwen Pan, Daniela Vullo, Seppo Parkkila, Clemente Capasso & Claudiu T. Supuran. (2013) Cloning, Characterization, and Inhibition Studies of a β-Carbonic Anhydrase from Leishmania donovani chagasi, the Protozoan Parasite Responsible for Leishmaniasis. Journal of Medicinal Chemistry 56:18, pages 7372-7381.
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Ramazan Ulus, İbrahim Yeşildağ, Muhammet Tanç, Metin Bülbül, Muharrem Kaya & Claudiu T. Supuran. (2013) Synthesis of novel acridine and bis acridine sulfonamides with effective inhibitory activity against the cytosolic carbonic anhydrase isoforms II and VII. Bioorganic & Medicinal Chemistry 21:18, pages 5799-5805.
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Janis Leitans, Agnese Sprudza, Muhammet Tanc, Igor Vozny, Raivis Zalubovskis, Kaspars Tars & Claudiu T. Supuran. (2013) 5-Substituted-(1,2,3-triazol-4-yl)thiophene-2-sulfonamides strongly inhibit human carbonic anhydrases I, II, IX and XII: Solution and X-ray crystallographic studies. Bioorganic & Medicinal Chemistry 21:17, pages 5130-5138.
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Christopher Boone, Andrew Habibzadegan, Sonika Gill & Robert McKenna. (2013) Carbonic Anhydrases and Their Biotechnological Applications. Biomolecules 3:4, pages 553-562.
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Christopher D. Boone, Andrew Habibzadegan, Chingkuang Tu, David N. Silverman & Robert McKenna. (2013) Structural and catalytic characterization of a thermally stable and acid-stable variant of human carbonic anhydrase II containing an engineered disulfide bond. Acta Crystallographica Section D Biological Crystallography 69:8, pages 1414-1422.
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Muhammet Tanc, Fabrizio Carta, Murat Bozdag, Andrea Scozzafava & Claudiu T. Supuran. (2013) 7-Substituted-sulfocoumarins are isoform-selective, potent carbonic anhydrase II inhibitors. Bioorganic & Medicinal Chemistry 21:15, pages 4502-4510.
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Fabrizio Carta, Atilla Akdemir, Andrea Scozzafava, Emanuela Masini & Claudiu T. Supuran. (2013) Xanthates and Trithiocarbonates Strongly Inhibit Carbonic Anhydrases and Show Antiglaucoma Effects in Vivo. Journal of Medicinal Chemistry 56:11, pages 4691-4700.
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Mayank Aggarwal, Christopher D. Boone, Bhargav Kondeti, Chingkuang Tu, David N. Silverman & Robert McKenna. (2013) Effects of cryoprotectants on the structure and thermostability of the human carbonic anhydrase II–acetazolamide complex. Acta Crystallographica Section D Biological Crystallography 69:5, pages 860-865.
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Christopher D. Boone, Sonika Gill, Andrew Habibzadegan & Robert McKenna. (2013) Carbonic Anhydrase: An Efficient Enzyme with Possible Global Implications. International Journal of Chemical Engineering 2013, pages 1-6.
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Mohamed-Chiheb Saada, Joanna Ombouma, Jean-Louis Montero, Claudiu T. Supuran & Jean-Yves Winum. (2013) Thiol–ene click chemistry for the synthesis of highly effective glycosyl sulfonamide carbonic anhydrase inhibitors. Chemical Communications 49:50, pages 5699.
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