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Original Article

Synthesis, bioevaluation and docking study of 5-substitutedphenyl-1,3,4-thiadiazole-based hydroxamic acids as histone deacetylase inhibitors and antitumor agents

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Pages 611-618 | Received 09 Jul 2013, Accepted 01 Aug 2013, Published online: 11 Sep 2013

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Le Cong Huan, Duong Tien Anh, Pham-The Hai, Lai Duc Anh, Eun Jae Park, A Young Ji, Jong Soon Kang, Do Thi Mai Dung, Dao Thi Kim Oanh, Truong Thanh Tung, Dinh Thi Thanh Hai, Sang-Bae Han & Nguyen-Hai Nam. (2020) Design, synthesis, and evaluation of novel N'-substituted-1-(4-chlorobenzyl)-1H-indol-3-carbohydrazides as antitumor agents. Journal of Enzyme Inhibition and Medicinal Chemistry 35:1, pages 1854-1865.
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Hao Zhou, Chengzhang Wang, Tao Deng, Ran Tao & Wenjun Li. (2018) Novel urushiol derivatives as HDAC8 inhibitors: rational design, virtual screening, molecular docking and molecular dynamics studies. Journal of Biomolecular Structure and Dynamics 36:8, pages 1966-1978.
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H. Pham-The, G. Casañola-Martin, K. Diéguez-Santana, N. Nguyen-Hai, N.T. Ngoc, L. Vu-Duc & H. Le-Thi-Thu. (2017) Quantitative structure–activity relationship analysis and virtual screening studies for identifying HDAC2 inhibitors from known HDAC bioactive chemical libraries. SAR and QSAR in Environmental Research 28:3, pages 199-220.
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