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Research Article

Design, synthesis and anticancer activity of oxoaporphine alkaloid derivatives

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Pages 722-727 | Received 03 Jun 2013, Accepted 04 Sep 2013, Published online: 25 Jun 2014

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Kuheli Das, Amitabha Datta, Chiara Massera, Catarina Roma-Rodrigues, Mariana Barroso, Pedro V. Baptista & Alexandra R. Fernandes. (2019) Structural aspects of a trimetallic CuII derivative: cytotoxicity and anti-proliferative activity on human cancer cell lines. Journal of Coordination Chemistry 72:5-7, pages 920-940.
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Articles from other publishers (8)

Jing Sun, Xingtian Zhan, Weimin Wang, Xiaojie Yang, Yichen Liu, Huanzhi Yang, Jianjun Deng & Haixia Yang. (2023) Natural aporphine alkaloids: A comprehensive review of phytochemistry, pharmacokinetics, anticancer activities, and clinical application. Journal of Advanced Research.
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Mohammad Fawad Ansari, Huzaifa Yasir Khan, Sartaj Tabassum & Farukh Arjmand. (2023) Advances in anticancer alkaloid-derived metallo-chemotherapeutic agents in the last decade: Mechanism of action and future prospects. Pharmacology & Therapeutics 241, pages 108335.
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Hui Zhong, Mingxuan Zhao, Chunyu Wu, Jiayao Zhang, Li Chen & Jianbo Sun. (2022) Development of oxoisoaporphine derivatives with topoisomerase I inhibition and reversal of multidrug resistance in breast cancer MCF-7/ADR cells. European Journal of Medicinal Chemistry 235, pages 114300.
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Lan-Shan Liao, Lin-Jie Tan, Yin Chen, Qi-Yuan Yang, Muhammad Iqbal Choudhary, Ying-Ming Pan, Hai-Tao Tang, Gui-Fa Su, Hong Liang & Zhen-Feng Chen. (2022) One-pot synthesis of oxoaporphines as potent antitumor agents and investigation of their mechanisms of actions. European Journal of Medicinal Chemistry 231, pages 114141.
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Majid M. Heravi, Neda Abedian‐Dehaghani, Vahideh Zadsirjan & Yalda Rangraz. (2021) Catalytic Function of Cu (I) and Cu (II) in Total Synthesis of Alkaloids. ChemistrySelect 6:34, pages 9230-9287.
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Yen-Ting Chen, Jih-Jung Chen & Hsiang-Tsui Wang. (2019) Targeting RNA Polymerase I with Hernandonine Inhibits Ribosomal RNA Synthesis and Tumor Cell Growth. Molecular Cancer Research 17:11, pages 2294-2305.
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Bo Zheng, Hui-Ya Qu, Tian-Zhuo Meng, Xia Lu, Jie Zheng, Yun-Gang He, Qi-Qi Fan & Xiao-Xin Shi. (2018) Novel total syntheses of oxoaporphine alkaloids enabled by mild Cu-catalyzed tandem oxidation/aromatization of 1-Bn-DHIQs. RSC Advances 8:51, pages 28997-29007.
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Felipe M.A. da Silva, Giovana A. Bataglion, Richardson A. de Almeida, Gabriel Heerdt, Iran L. Sousa, Francinaldo A. da Silva Filho, Danielle C. de Alencar, Emmanoel V. Costa, Afonso D.L. de Souza, Maria L.B. Pinheiro, Nelson H. Morgon & Hector H.F. Koolen. (2017) Positive electrospray ionization ion trap mass spectrometry and ab initio computational studies of the multi-pathway fragmentation of oxoaporphine alkaloids. International Journal of Mass Spectrometry 418, pages 30-36.
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