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Journal of Enzyme Inhibition and Medicinal Chemistry Volume 30, 2015 - Issue 4
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Research Article

Cytotoxic activities of some benzothiazole-piperazine derivatives

Enise Ece GurdalDepartment of Pharmaceutical Chemistry, Faculty of Pharmacy, Yeditepe University, Kayisdagi, Istanbul, Turkey and Correspondence[email protected]
,
Irem DurmazDepartment of Molecular Biology and Genetics, BilGen, Genetics and Biotechnology Research Center, Faculty of Science, Bilkent University, Bilkent, Ankara, Turkey
,
Rengul Cetin-AtalayDepartment of Molecular Biology and Genetics, BilGen, Genetics and Biotechnology Research Center, Faculty of Science, Bilkent University, Bilkent, Ankara, Turkey
&
Mine YarimDepartment of Pharmaceutical Chemistry, Faculty of Pharmacy, Yeditepe University, Kayisdagi, Istanbul, Turkey and
Pages 649-654 | Received 21 Aug 2014, Accepted 21 Aug 2014, Published online: 21 Oct 2014

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Livio Racané, Valentina Rep, Sandra Kraljević Pavelić, Petra Grbčić, Iva Zonjić, Marijana Radić Stojković, Martin C. Taylor, John M. Kelly & Silvana Raić-Malić. (2021) Synthesis, antiproliferative and antitrypanosomal activities, and DNA binding of novel 6-amidino-2-arylbenzothiazoles. Journal of Enzyme Inhibition and Medicinal Chemistry 36:1, pages 1952-1967.
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Dong-Jun Fu, Si-Meng Liu, Fu-Hao Li, Jia-Jia Yang & Jun Li. (2020) Antiproliferative benzothiazoles incorporating a trimethoxyphenyl scaffold as novel colchicine site tubulin polymerisation inhibitors. Journal of Enzyme Inhibition and Medicinal Chemistry 35:1, pages 1050-1059.
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Ali Irfan, Fozia Batool, Syeda Andleeb Zahra Naqvi, Amjad Islam, Sameh M. Osman, Alessio Nocentini, Siham A. Alissa & Claudiu T. Supuran. (2020) Benzothiazole derivatives as anticancer agents. Journal of Enzyme Inhibition and Medicinal Chemistry 35:1, pages 265-279.
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Anna Różycka, Patryk Fryń, Agnieszka Iwan, Krzysztof Artur Bogdanowicz, Michal Filapek, Natalia Górska, Paweł Dąbczyński, Jakub Rysz, Damian Pociecha, Agnieszka Hreniak & Monika Marzec. (2018) Thermal, structural and electrochemical properties of new aliphatic-aromatic imine with piperazine moieties blended with titanium dioxide. Phase Transitions 91:2, pages 210-224.
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Krishnan Sampath, Maruthachalam Mohanraj & Chinnasamy Jayabalakrishnan. (2017) DNA interaction and antioxidant studies of ruthenium(II) complexes containing mixed ligands. Inorganic and Nano-Metal Chemistry 47:7, pages 1049-1056.
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Nazariy Pokhodylo, Nataliya Finiuk, Olha Klyuchivska, Rostyslav Stoika, Vasyl Matiychuk & Mykola Obushak. (2023) Bioisosteric replacement of 1H-1,2,3-triazole with 1H-tetrazole ring enhances anti-leukemic activity of (5-benzylthiazol-2-yl)benzamides. European Journal of Medicinal Chemistry 250, pages 115126.
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Hamzeh Kiyani & Ziba Daroughezadeh. (2022) Efficient and Aqoues Synthesis of 3,4-Disubstituted Isoxazol-5(4H)-one Derivatives Using Piperazine under Green Conditions. HETEROCYCLES 104:9, pages 1625.
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Gothandam Ladha & Kadirvelu Jeevaratnam. (2020) A novel antibacterial compound produced by Lactobacillus plantarum LJR13 isolated from rumen liquor of goat effectively controls multi-drug resistant human pathogens. Microbiological Research 241, pages 126563.
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Thuraya Al-Harthy, Wajdi Zoghaib & Raid Abdel-Jalil. (2020) Importance of Fluorine in Benzazole Compounds. Molecules 25:20, pages 4677.
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Nandini Pathak, Ekta Rathi, Nitesh Kumar, Suvarna G. Kini & C. Mallikarjuna Rao. (2020) A Review on Anticancer Potentials of Benzothiazole Derivatives. Mini-Reviews in Medicinal Chemistry 20:1, pages 12-23.
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Eman Bobtaina, Enise Ece Gurdal, Irem Durmaz, Rengul Cetin Atalay & Mine Yarim. (2018) Synthesis and Cytotoxicity Studies on Novel Piperazinylacetamides. Letters in Drug Design & Discovery 16:1, pages 45-51.
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Irena Sović, Samy Jambon, Sandra Kraljević Pavelić, Elitza Markova-Car, Nataša Ilić, Sabine Depauw, Marie-Hélène David-Cordonnier & Grace Karminski-Zamola. (2018) Synthesis, antitumor activity and DNA binding features of benzothiazolyl and benzimidazolyl substituted isoindolines. Bioorganic & Medicinal Chemistry 26:8, pages 1950-1960.
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Zhilin Wu, Na Ding, Yuting Tang, Jiao Ye, Junmei Peng & Aixi Hu. (2017) Synthesis and antitumor activity of novel N-(5-benzyl-4-(tert-butyl)thiazol-2-yl)-2-(piperazin-1-yl)acetamides. Research on Chemical Intermediates 43:8, pages 4833-4850.
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Sean W. Reilly, Nikaela W. Bryan & Robert H. Mach. (2017) Pd-catalyzed arylation of linear and angular spirodiamine salts under aerobic conditions. Tetrahedron Letters 58:5, pages 466-469.
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Furkan Özen, Suat Tekin, Kenan Koran, Süleyman Sandal & Ahmet Orhan Görgülü. (2016) Synthesis of 2-(2,3,4-trimethoxyphenyl)-1-(substituted-phenyl)acrylonitriles: in vitro anticancer activity against MCF-7, PC-3 and A2780 cancer cell lines. Research on Chemical Intermediates 42:12, pages 7793-7805.
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Sean W. Reilly & Robert H. Mach. (2016) Pd-Catalyzed Synthesis of Piperazine Scaffolds Under Aerobic and Solvent-Free Conditions. Organic Letters 18:20, pages 5272-5275.
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