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Journal of Enzyme Inhibition and Medicinal Chemistry Volume 31, 2016 - Issue 3
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Original Articles

Synthesis, antitumor activity evaluation of some new N-aroyl-α,β-unsaturated piperidones with fluorescence

Jufeng SunSchool of Pharmacy, Binzhou Medical University, Yantai, Shandong, P.R. China and Correspondence[email protected]
,
Suwen WangYantai Yuhuangding Hospital Emergency, Yantai, Shandong, P.R. China
,
Hongjuan LiSchool of Pharmacy, Binzhou Medical University, Yantai, Shandong, P.R. China and
,
Wenguo JiangSchool of Pharmacy, Binzhou Medical University, Yantai, Shandong, P.R. China and
,
Guige HouSchool of Pharmacy, Binzhou Medical University, Yantai, Shandong, P.R. China and
,
Feng ZhaoSchool of Pharmacy, Binzhou Medical University, Yantai, Shandong, P.R. China and
&
Wei CongSchool of Pharmacy, Binzhou Medical University, Yantai, Shandong, P.R. China and
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Pages 495-502 | Received 12 Jan 2015, Accepted 11 Apr 2015, Published online: 18 Sep 2015

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Wei Cong, Yue Sun, Yi-Fan Sun, Wei-Bin Yan, Yu-Long Zhang, Zhong-Fei Gao, Chun-Hua Wang, Gui-Ge Hou & Jia-Jing Zhang. (2021) Trifluoromethyl-substituted 3,5-bis(arylidene)-4-piperidones as potential anti-hepatoma and anti-inflammation agents by inhibiting NF-кB activation. Journal of Enzyme Inhibition and Medicinal Chemistry 36:1, pages 1621-1630.
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Chang-Ming Su, Gui-Ge Hou, Chun-Hua Wang, Hong-Qin Zhang, Cheng Yang, Mei Liu & Yun Hou. (2019) Potential multifunctional agents with anti-hepatoma and anti-inflammation properties by inhibiting NF-кB activation. Journal of Enzyme Inhibition and Medicinal Chemistry 34:1, pages 1287-1297.
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Lianshuang Zhang, Qin Chen, Guige Hou, Wei Zhao & Yun Hou. (2019) Hydroxyl-substituted double Schiff-base condensed 4-piperidone/cyclohexanones as potential anticancer agents with biological evaluation. Journal of Enzyme Inhibition and Medicinal Chemistry 34:1, pages 264-271.
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Articles from other publishers (12)

Martina Bazzaro & Stig Linder. (2020) Dienone Compounds: Targets and Pharmacological Responses. Journal of Medicinal Chemistry 63:24, pages 15075-15093.
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Dhaifallah M. Al-thamili, Abdulrahman I. Almansour, Natarajan Arumugam, Sevgi Kansız, Necmi Dege, Saied M. Soliman, Mohammad Azam & Raju Suresh Kumar. (2020) Highly functionalized N-1-(2-pyridinylmethyl)-3,5-bis[(E)-arylmethylidene]tetrahydro-4(1H)-pyridinones: Synthesis, characterization, crystal structure and DFT studies. Journal of Molecular Structure 1222, pages 128940.
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Sze Wei Leong, Suet Lin Chia, Faridah Abas & Khatijah Yusoff. (2020) In-Vitro and In-Silico Evaluations of Heterocyclic-Containing Diarylpentanoids as Bcl-2 Inhibitors Against LoVo Colorectal Cancer Cells. Molecules 25:17, pages 3877.
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Rossella Fioravanti, Stefano Tomassi, Elisabetta Di Bello, Annalisa Romanelli, Andrea Maria Plateroti, Rosaria Benedetti, Mariarosaria Conte, Ettore Novellino, Lucia Altucci, Sergio Valente & Antonello Mai. (2020) Properly Substituted Cyclic Bis-(2-bromobenzylidene) Compounds Behaved as Dual p300/CARM1 Inhibitors and Induced Apoptosis in Cancer Cells. Molecules 25:14, pages 3122.
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Bin-Rong Yao, Yue Sun, Shuang-Long Chen, Hao-Dong Suo, Yu-Long Zhang, Hao Wei, Chun-Hua Wang, Feng Zhao, Wei Cong, Wen-Yu Xin & Gui-Ge Hou. (2019) Dissymmetric pyridyl-substituted 3,5-bis(arylidene)-4-piperidones as anti-hepatoma agents by inhibiting NF-κB pathway activation. European Journal of Medicinal Chemistry 167, pages 187-199.
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Riham F George, Nermin Samir, Iriny M Ayoub, ElSayed M Shalaby, Nicola Demitri & Michael Wink. (2018) Synthesis, antiproliferative activity and 2D-QSAR study of some 8-alkyl-2,4-bisbenzylidene-3-nortropinones. Future Medicinal Chemistry 10:24, pages 2815-2833.
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Lian-Dong Liu, Shu-Lian Liu & Gui-Ge Hou. (2018) Crystal structure of 4-(( E )-(( E )-5-(2-fluorobenzylidene)-1-((4-fluorophenyl)sulfonyl)-4-oxopiperidin-3-ylidene)methyl)benzonitrile, C 26 H 18 F 2 N 2 O 3 S . Zeitschrift für Kristallographie - New Crystal Structures 233:6, pages 1063-1065.
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Ning Li, Xianyong Bai, Lianshuang Zhang & Yun Hou. (2018) Synthesis, crystal structures and anti-inflammatory activity of four 3,5-bis(arylidene)- N -benzenesulfonyl-4-piperidone derivatives . Acta Crystallographica Section C Structural Chemistry 74:10, pages 1171-1179.
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Ning Li, Wen-Yu Xin, Bin-Rong Yao, Wei Cong, Chun-Hua Wang & Gui-Ge Hou. (2018) N-phenylsulfonyl-3,5-bis(arylidene)-4-piperidone derivatives as activation NF-κB inhibitors in hepatic carcinoma cell lines. European Journal of Medicinal Chemistry 155, pages 531-544.
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Binrong Yao, Ning Li, Chunhua Wang, Guige Hou, Qingguo Meng & Ke Yan. (2018) Novel asymmetric 3,5-bis(arylidene)piperidin-4-one derivatives: synthesis, crystal structures and cytotoxicity. Acta Crystallographica Section C Structural Chemistry 74:6, pages 659-665.
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Ning Li, Wen-Yu Xin, Bin-Rong Yao, Chun-Hua Wang, Wei Cong, Feng Zhao, Hong-Juan Li, Yun Hou, Qing-Guo Meng & Gui-Ge Hou. (2018) Novel dissymmetric 3,5-bis(arylidene)-4-piperidones as potential antitumor agents with biological evaluation in vitro and in vivo. European Journal of Medicinal Chemistry 147, pages 21-33.
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Ju-feng Sun, Gui-ge Hou, Feng Zhao, Wei Cong, Hong-juan Li, Wen-shuai Liu & Chunhua Wang. (2016) Synthesis, Antiproliferative, and Multidrug Resistance Reversal Activities of Heterocyclic α , β -Unsaturated Carbonyl Compounds . Chemical Biology & Drug Design 88:4, pages 534-541.
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