Journal of Enzyme Inhibition and Medicinal Chemistry, Volume 31, Issue 3 (2016)

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Journal of Enzyme Inhibition and Medicinal Chemistry, Volume 31, Issue 3 (2016)

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Review Article

How many carbonic anhydrase inhibition mechanisms exist?
Claudiu T. Supuran
Pages: 345-360
Published online: 30 Nov 2015
AbstractforHow many carbonic anhydrase inhibition mechanisms exist? | Full Text | References | PDF (1.6 MB)
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Research Article

Article
Synthesis and antiviral activity of 1-(1,3-disubstitutedimidazolidyn-2-ylidene)-3-ethoxycarbonylmethylurea derivatives
Marzena Rządkowska, Elżbieta Szacoń, Agnieszka A. Kaczor, Barbara Rajtar, Łukasz Świątek, Małgorzata Polz-Dacewicz & Dariusz Matosiuk
Pages: 361-368
Published online: 23 Mar 2015
AbstractforSynthesis and antiviral activity of 1-(1,3-disubstitutedimidazolidyn-2-ylidene)-3-ethoxycarbonylmethylurea derivatives | Full Text | References | PDF (731.5 KB)
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Article
Indole-based hydrazide-hydrazones and 4-thiazolidinones: synthesis and evaluation as antitubercular and anticancer agents
Gökçe Cihan-Üstündağ, Dilek Şatana, Gül Özhan & Gültaze Çapan
Pages: 369-380
Published online: 24 Apr 2015
AbstractforIndole-based hydrazide-hydrazones and 4-thiazolidinones: synthesis and evaluation as antitubercular and anticancer agents | Full Text | References | PDF (382.2 KB)
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Article
Relaxant effects of selected sildenafil analogues in the rat aorta
Mariusz Mojzych, Monika Kubacka, Szczepan Mogilski, Barbara Filipek & Emilia Fornal
Pages: 381-388
Published online: 23 Mar 2015
AbstractforRelaxant effects of selected sildenafil analogues in the rat aorta | Full Text | References | PDF (946 KB)
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Article
Dual functional cholinesterase and MAO inhibitors for the treatment of Alzheimer’s disease: synthesis, pharmacological analysis and molecular modeling of homoisoflavonoid derivatives
Yali Wang, Yang Sun, Yueyan Guo, Zechen Wang, Ling Huang & Xingshu Li
Pages: 389-397
Published online: 23 Mar 2015
AbstractforDual functional cholinesterase and MAO inhibitors for the treatment of Alzheimer’s disease: synthesis, pharmacological analysis and molecular modeling of homoisoflavonoid derivatives | Full Text | References | PDF (1.3 MB) | Supplemental
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Article
Searching for indole derivatives as potential mushroom tyrosinase inhibitors
Stefania Ferro, Giovanna Certo, Laura De Luca, Maria Paola Germanò, Antonio Rapisarda & Rosaria Gitto
Pages: 398-403
Published online: 31 Mar 2015
AbstractforSearching for indole derivatives as potential mushroom tyrosinase inhibitors | Full Text | References | PDF (549.9 KB)
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Article
Carbonic anhydrase IX correlates with survival and is a potential therapeutic target for neuroblastoma
Helen M. Ameis, Astrid Drenckhan, Morton Freytag, Jakob R. Izbicki, Claudiu T. Supuran, Konrad Reinshagen, Stefan Holland-Cunz & Stephanie J. Gros
Pages: 404-409
Published online: 17 Apr 2015
AbstractforCarbonic anhydrase IX correlates with survival and is a potential therapeutic target for neuroblastoma | Full Text | References | PDF (671.4 KB)
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Article
Synthesis and evaluation of naphthalene-based thiosemicarbazone derivatives as new anticancer agents against LNCaP prostate cancer cells
Mehlika Dilek Altintop, Belgin Sever, Ahmet Özdemir, Gökhan Kuş, Pinar Oztopcu-Vatan, Selda Kabadere & Zafer Asim Kaplancikli
Pages: 410-416
Published online: 31 Mar 2015
AbstractforSynthesis and evaluation of naphthalene-based thiosemicarbazone derivatives as new anticancer agents against LNCaP prostate cancer cells | Full Text | References | PDF (755.2 KB)
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Article
In silico modeling of β-carbonic anhydrase inhibitors from the fungus Malassezia globosa as antidandruff agents
Shalini Singh & Claudiu T. Supuran
Pages: 417-424
Published online: 06 May 2015
AbstractforIn silico modeling of β-carbonic anhydrase inhibitors from the fungus Malassezia globosa as antidandruff agents | Full Text | References | PDF (471.2 KB) | Supplemental
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Article
Discovering novel carbonic anhydrase type IX (CA IX) inhibitors from seven million compounds using virtual screening and in vitro analysis
Ramin Ekhteiari Salmas, Murat Senturk, Mine Yurtsever & Serdar Durdagi
Pages: 425-433
Published online: 07 May 2015
AbstractforDiscovering novel carbonic anhydrase type IX (CA IX) inhibitors from seven million compounds using virtual screening and in vitro analysis | Full Text | References | PDF (3 MB) | Supplemental
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Article
Design, synthesis and biological evaluation of 4-benzoyl-1-dichlorobenzoylthiosemicarbazides as potent Gram-positive antibacterial agents
Agata Paneth, Tomasz Plech, Barbara Kaproń, Dominika Hagel, Urszula Kosikowska, Edyta Kuśmierz, Katarzyna Dzitko & Piotr Paneth
Pages: 434-440
Published online: 21 Apr 2015
AbstractforDesign, synthesis and biological evaluation of 4-benzoyl-1-dichlorobenzoylthiosemicarbazides as potent Gram-positive antibacterial agents | Full Text | References | PDF (213.5 KB)
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Article
Acetylcholinesterase and carbonic anhydrase isoenzymes I and II inhibition profiles of taxifolin
Hulya Gocer, Fevzi Topal, Meryem Topal, Murat Küçük, Dilek Teke, İlhami Gülçin, Saleh H. Alwasel & Claudiu T. Supuran
Pages: 441-447
Published online: 20 Apr 2015
AbstractforAcetylcholinesterase and carbonic anhydrase isoenzymes I and II inhibition profiles of taxifolin | Full Text | References | PDF (358.9 KB)
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Article
Docking study: PPARs interaction with the selected alternative plasticizers to di(2-ethylhexyl) phthalate
Nicolas Kambia, Amaury Farce, Karim Belarbi, Bernard Gressier, Michel Luyckx, Philippe Chavatte & Thierry Dine
Pages: 448-455
Published online: 05 May 2015
AbstractforDocking study: PPARs interaction with the selected alternative plasticizers to di(2-ethylhexyl) phthalate | Full Text | References | PDF (4 MB)
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Article
Studies of C-terminal naphthoquinone dipeptides as 20S proteasome inhibitors
Alessandra Scotti, Claudio Trapella, Valeria Ferretti, Eleonora Gallerani, Riccardo Gavioli & Mauro Marastoni
Pages: 456-463
Published online: 05 May 2015
AbstractforStudies of C-terminal naphthoquinone dipeptides as 20S proteasome inhibitors | Full Text | References | PDF (805.1 KB)
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Article
Neuroprotective effects of (E)-3,4-diacetoxystyryl sulfone and sulfoxide derivatives in vitro models of Parkinson's disease
Xianling Ning, Mengmeng Yuan, Ying Guo, Chao Tian, Xiaowei Wang, Zhili Zhang & Junyi Liu
Pages: 464-469
Published online: 15 Jul 2015
AbstractforNeuroprotective effects of (E)-3,4-diacetoxystyryl sulfone and sulfoxide derivatives in vitro models of Parkinson's disease | Full Text | References | PDF (684 KB)
  • 691 Views
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Article
Synthesis, structure, antimycobacterial and anticancer evaluation of new pyrrolo-phenanthroline derivatives
Cristina M. Al Matarneh, Ionel I. Mangalagiu, Sergiu Shova & Ramona Danac
Pages: 470-480
Published online: 06 May 2015
AbstractforSynthesis, structure, antimycobacterial and anticancer evaluation of new pyrrolo-phenanthroline derivatives | Full Text | References | PDF (1.1 MB) | Supplemental
  • 1064 Views
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Article
Searching for novel scaffold of triazole non-nucleoside inhibitors of HIV-1 reverse transcriptase
Tomasz Frączek, Agata Paneth, Rafał Kamiński, Agnieszka Krakowiak & Piotr Paneth
Pages: 481-489
Published online: 05 May 2015
AbstractforSearching for novel scaffold of triazole non-nucleoside inhibitors of HIV-1 reverse transcriptase | Full Text | References | PDF (379.1 KB)
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Article
Honey as an apitherapic product: its inhibitory effect on urease and xanthine oxidase
Huseyin Sahin
Pages: 490-494
Published online: 05 May 2015
AbstractforHoney as an apitherapic product: its inhibitory effect on urease and xanthine oxidase | Full Text | References | PDF (132.2 KB)
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Original Articles

Article
Synthesis, antitumor activity evaluation of some new N-aroyl-α,β-unsaturated piperidones with fluorescence
Jufeng Sun, Suwen Wang, Hongjuan Li, Wenguo Jiang, Guige Hou, Feng Zhao & Wei Cong
Pages: 495-502
Published online: 18 Sep 2015
AbstractforSynthesis, antitumor activity evaluation of some new N-aroyl-α,β-unsaturated piperidones with fluorescence | Full Text | References | PDF (1 MB) | Supplemental
  • 891 Views
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Research Article

Article
Spirobisnaphthalenes effectively inhibit carbonic anhydrase
Hulya Gocer, Abdulselam Aslan, İlhami Gülçin & Claudiu T. Supuran
Pages: 503-507
Published online: 28 May 2015
AbstractforSpirobisnaphthalenes effectively inhibit carbonic anhydrase | Full Text | References | PDF (185.8 KB)
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Article
QSAR and docking studies of anthraquinone derivatives by similarity cluster prediction
Alexandra M. Harsa, Teodora E. Harsa & Mircea V. Diudea
Pages: 508-515
Published online: 28 May 2015
AbstractforQSAR and docking studies of anthraquinone derivatives by similarity cluster prediction | Full Text | References | PDF (597.4 KB)
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