Advanced search
Publication Cover
Journal of Enzyme Inhibition and Medicinal Chemistry Volume 31, 2016 - Issue 4
Submit an article Journal homepage
1,107
Views
12
CrossRef citations to date
0
Altmetric
Research Article

Discovery of nitroaryl urea derivatives with antiproliferative properties

Tomasz M. WróbelDepartment of Synthesis and Chemical Technology of Pharmaceutical Substances and Correspondence[email protected]
,
Michał KiełbusDepartment of Biochemistry and Molecular Biology, Medical University of Lublin, Lublin, Poland,
,
Agnieszka A. KaczorDepartment of Synthesis and Chemical Technology of Pharmaceutical Substances and ;School of Pharmacy, University of Eastern Finland, Kuopio, Finland,
,
Vladimír KryštofLaboratory of Growth Regulators, Centre of the Region Haná for Biotechnological and Agricultural Research, Institute of Experimental Botany ASCR & Palacký University, Olomouc, Czech Republic,
,
Zbigniew KarczmarzykDepartment of Chemistry, Siedlce University of Natural Sciences and Humanities, Siedlce, Poland, and
,
Waldemar WysockiDepartment of Chemistry, Siedlce University of Natural Sciences and Humanities, Siedlce, Poland, and
,
Andrzej FruzińskiInstitute of General and Ecological Chemistry, Technical University of Lodz, Lodz, Poland
,
Sylwia K. KrólDepartment of Biochemistry and Molecular Biology, Medical University of Lublin, Lublin, Poland,
,
Aneta GrabarskaDepartment of Biochemistry and Molecular Biology, Medical University of Lublin, Lublin, Poland,
,
Andrzej StepulakDepartment of Biochemistry and Molecular Biology, Medical University of Lublin, Lublin, Poland,
&
Dariusz MatosiukDepartment of Synthesis and Chemical Technology of Pharmaceutical Substances and
show all
Pages 608-618 | Received 17 Feb 2015, Accepted 19 May 2015, Published online: 26 Jun 2015

Citations (12)

Keep up to date with the latest research on this topic with citation updates for this article.

Subscribe to citation updates

Read on this site (1)

Ahmed M. Shawky, Nashwa A. Ibrahim, Mohammed A. S. Abourehab, Ashraf N. Abdalla & Ahmed M. Gouda. (2021) Pharmacophore-based virtual screening, synthesis, biological evaluation, and molecular docking study of novel pyrrolizines bearing urea/thiourea moieties with potential cytotoxicity and CDK inhibitory activities. Journal of Enzyme Inhibition and Medicinal Chemistry 36:1, pages 15-33.
Read now

Articles from other publishers (11)

Linwei Li, Songtao Liu, Bi Wang, Fei Liu, Shu Xu, Pirui Li & Yu Chen. (2023) An Updated Review on Developing Small Molecule Kinase Inhibitors Using Computer-Aided Drug Design Approaches. International Journal of Molecular Sciences 24:18, pages 13953.
Crossref
Yuanci Li, Zhiqiang Feng & Hongjuan Tong. (2023) The crystal structure of 1-(2-chlorophenyl)-3-cycloheptylurea, C 14 H 19 ClN 2 O . Zeitschrift für Kristallographie - New Crystal Structures 238:3, pages 547-549.
Crossref
Yusuf Akbaba. (2022) A straightforward synthesis of potentially biologically active novel urea derivatives from 1,2,3,4-tetrahydronaphthalene-2-carboxylic acids. Monatshefte für Chemie - Chemical Monthly 153:12, pages 1251-1259.
Crossref
Yusuf Akbaba, Fatma Necmiye Kacı & Süleyman Göksu. (2022) Substituted Tetrahydronaphthalen‐1‐yl‐phenethyl Ureas: Synthesis, Characterization, and Biological Evaluations. ChemistrySelect 7:15.
Crossref
Mohammad Y. Alfaifi, Ali A. Shati, Serag Eldin I. Elbehairi, Reda F. M. Elshaarawy & Emad M. Gad. (2022) Fine-tuning of the pharmacological potential of novel thiazolium ionic liquids by anion alteration. RSC Advances 12:1, pages 458-469.
Crossref
Sylwia K. Król, Ewa Bębenek, Magdalena Dmoszyńska-Graniczka, Adrianna Sławińska-Brych, Stanisław Boryczka & Andrzej Stepulak. (2021) Acetylenic Synthetic Betulin Derivatives Inhibit Akt and Erk Kinases Activity, Trigger Apoptosis and Suppress Proliferation of Neuroblastoma and Rhabdomyosarcoma Cell Lines. International Journal of Molecular Sciences 22:22, pages 12299.
Crossref
Jingjing Zhang, Yingqi Mi, Xueqi Sun, Yuan Chen, Qin Miao, Wenqiang Tan, Qing Li, Fang Dong & Zhanyong Guo. (2020) Improved Antioxidant and Antifungal Activity of Chitosan Derivatives Bearing Urea Groups. Starch - Stärke 72:5-6.
Crossref
Mozhdeh Mozaffari & Najmeh Nowrouzi. (2019) Palladium‐Catalyzed Synthesis of Symmetrical and Unsymmetrical Ureas Using Chromium Hexacarbonyl as a Convenient and Safe Alternative Carbonyl Source. European Journal of Organic Chemistry 2019:46, pages 7541-7544.
Crossref
Saroj, Om P.S. Patel, Krishnan Rangan & Anil Kumar. (2019) Metal-free synthesis of pyridin-2-yl ureas from 2-aminopyridinium salts. Tetrahedron Letters 60:33, pages 150939.
Crossref
Mahadev Patil, Anurag Noonikara Poyil, Shrinivas D. Joshi, Shivaputra A. Patil, Siddappa A. Patil & Alejandro Bugarin. (2019) Synthesis, molecular docking studies, and antimicrobial evaluation of new structurally diverse ureas. Bioorganic Chemistry 87, pages 302-311.
Crossref
Tomasz Wróbel, Urszula Kosikowska, Agnieszka Kaczor, Sylwia Andrzejczuk, Zbigniew Karczmarzyk, Waldemar Wysocki, Zofia Urbańczyk-Lipkowska, Maja Morawiak & Dariusz Matosiuk. (2015) Synthesis, Structural Studies and Molecular Modelling of a Novel Imidazoline Derivative with Antifungal Activity. Molecules 20:8, pages 14761-14776.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.