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COPD: Journal of Chronic Obstructive Pulmonary Disease Volume 8, 2011 - Issue 2
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ORIGINAL RESEARCH

Statin Therapy is Associated with Decreased Pulmonary Vascular Pressures in Severe COPD

Robert M. ReedUniversity of Maryland School of Medicine, Division of Pulmonary and Critical Care Medicine, Baltimore, Maryland, USA,Correspondence[email protected]
,
Aldo IaconoUniversity of Maryland School of Medicine, Division of Pulmonary and Critical Care Medicine, Baltimore, Maryland, USA,
,
Andrew DeFilippisJohns Hopkins University School of Medicine, Division of Cardiology, Baltimore, Maryland, USA
,
Steven JonesJohns Hopkins University School of Medicine, Division of Cardiology, Baltimore, Maryland, USA
,
Michael EberleinJohns Hopkins University School of Medicine, Division of Pulmonary and Critical Care Medicine, Baltimore, Maryland, USA,
,
Noah LechtzinJohns Hopkins University School of Medicine, Division of Pulmonary and Critical Care Medicine, Baltimore, Maryland, USA,
&
Reda E. GirgisJohns Hopkins University School of Medicine, Division of Pulmonary and Critical Care Medicine, Baltimore, Maryland, USA,
 show all
Pages 96-102 | Published online: 15 Apr 2011

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Jonathan R Weir-McCall, Patrick SK Liu-Shiu-Cheong, Allan D Struthers, Brian J Lipworth & J Graeme Houston. (2018) Disconnection of pulmonary and systemic arterial stiffness in COPD. International Journal of Chronic Obstructive Pulmonary Disease 13, pages 1755-1765.
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J Michael Wells & Mark T Dransfield. (2013) Pathophysiology and clinical implications of pulmonary arterial enlargement in COPD. International Journal of Chronic Obstructive Pulmonary Disease 8, pages 509-521.
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Articles from other publishers (23)

Laurent Calvier, Joachim Herz & Georg Hansmann. (2022) Interplay of Low-Density Lipoprotein Receptors, LRPs, and Lipoproteins in Pulmonary Hypertension. JACC: Basic to Translational Science 7:2, pages 164-180.
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Ragdah Arif, Arjun Pandey, Ying Zhao, Kyle Arsenault-Mehta, Danya Khoujah & Sanjay Mehta. (2022) Treatment of pulmonary hypertension associated with COPD: a systematic review. ERJ Open Research 8:1, pages 00348-2021.
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Marija Gredic, Isabel Blanco, Gabor Kovacs, Zsuzsanna Helyes, Péter Ferdinandy, Horst Olschewski, Joan Albert Barberà & Norbert Weissmann. (2020) Pulmonary hypertension in chronic obstructive pulmonary disease. British Journal of Pharmacology 178:1, pages 132-151.
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Reem Faraj, Danyelle Paine, Stephen M. Black & Ting Wang. 2021. Lung Inflammation in Health and Disease, Volume I. Lung Inflammation in Health and Disease, Volume I 33 56 .
Wen-Ting Wu & Chung-Yu Chen. (2020) Protective Effect of Statins on Pulmonary Hypertension in Chronic Obstructive Pulmonary Disease Patients: A Nationwide Retrospective, Matched Cohort Study. Scientific Reports 10:1.
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Peta Bradbury, Daniela Traini, Alaina J. Ammit, Paul M. Young & Hui Xin Ong. (2018) Repurposing of statins via inhalation to treat lung inflammatory conditions. Advanced Drug Delivery Reviews 133, pages 93-106.
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Lei Wang, Ting Yang & Chen Wang. (2017) Are statins beneficial for the treatment of pulmonary hypertension?. Chronic Diseases and Translational Medicine 3:4, pages 213-220.
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Luise Holzhauser, Ninel Hovnanians, Parham Eshtehardi, M. Khalid Mojadidi, Yi Deng, David Goodman-Meza, Pavlos Msaouel, Yi-An Ko & Ronald Zolty. (2017) Statin therapy improves survival in patients with severe pulmonary hypertension: a propensity score matching study. Heart and Vessels 32:8, pages 969-976.
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Norbert F. Voelkel, Shiro Mizuno & Carlyne D. Cool. 2017. COPD. COPD 195 207 .
Li Zuo, Chia-Chen Chuang, Alexander D. Clark, Davis E. Garrison, Jamie L. Kuhlman & David C. Sypert. 2017. Pulmonary Vasculature Redox Signaling in Health and Disease. Pulmonary Vasculature Redox Signaling in Health and Disease 399 411 .
Lin Wang, Moying Qu, Yao Chen, Yaxiong Zhou & Zhi Wan. (2016) Statins Have No Additional Benefit for Pulmonary Hypertension: A Meta-Analysis of Randomized Controlled Trials. PLOS ONE 11:12, pages e0168101.
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Magdalena Rysz-Górzynska, Anna Gluba-Brzózka, Amirhossein Sahebkar, Maria-Corina Serban, Dimitri P. Mikhailidis, Sorin Ursoniu, Peter P. Toth, Vera Bittner, Gerald F. Watts, Gregory Y. H. Lip, Jacek Rysz, Alberico L. Catapano & Maciej Banach. (2016) Efficacy of Statin Therapy in Pulmonary Arterial Hypertension: A Systematic Review and Meta-Analysis. Scientific Reports 6:1.
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Chao Cao, Yinfang Wu, Zhiwei Xu, Dan Lv, Chao Zhang, Tianwen Lai, Wen Li & Huahao Shen. (2015) The effect of statins on chronic obstructive pulmonary disease exacerbation and mortality: a systematic review and meta-analysis of observational research. Scientific Reports 5:1.
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Jérôme Lane, Stephan F. van Eeden, Ma’en Obeidat, Don D. Sin, Scott J. Tebbutt, Wim Timens, Dirkje S. Postma, Michel Laviolette, Peter D. Paré & Yohan Bossé. (2015) Impact of Statins on Gene Expression in Human Lung Tissues. PLOS ONE 10:11, pages e0142037.
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Jonathan R. Weir-McCall, Allan D. Struthers, Brian J. Lipworth & J. Graeme Houston. (2015) The role of pulmonary arterial stiffness in COPD. Respiratory Medicine 109:11, pages 1381-1390.
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Seyed Ali Javad Moosavi, Hanieh Raji, Masoomeh Faghankhani, Rostam Yazdani & Mansour Esmaeili. (2013) Evaluation of the Effects of Atorvastatin on the Treatment of Secondary Pulmonary Hypertension due to Chronic Obstructive Pulmonary Diseases: A Randomized Controlled Trial. Iranian Red Crescent Medical Journal 15:8, pages 649-654.
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Gaofeng Zhao, Yong-Ming Yu, Masao Kaneki, Ronald G. Tompkins & Alan J. Fischman. (2013) Simvastatin Protects Hepatocytes From Apoptosis by Suppressing the TNF-α/Caspase-3 Signaling Pathway in Mice With Burn Injury. Annals of Surgery 257:6, pages 1129-1136.
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J. Michael Wells, George R. Washko, MeiLan K. Han, Naseer Abbas, Hrudaya Nath, A. James Mamary, Elizabeth Regan, William C. Bailey, Fernando J. Martinez, Elizabeth Westfall, Terri H. Beaty, Douglas Curran-Everett, Jeffrey L. Curtis, John E. Hokanson, David A. Lynch, Barry J. Make, James D. Crapo, Edwin K. Silverman, Russell P. Bowler & Mark T. Dransfield. (2012) Pulmonary Arterial Enlargement and Acute Exacerbations of COPD. New England Journal of Medicine 367:10, pages 913-921.
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Todd M. Kolb & Paul M. Hassoun. (2012) Right Ventricular Dysfunction in Chronic Lung Disease. Cardiology Clinics 30:2, pages 243-256.
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PIERA BOSCHETTO, BIANCA BEGHÉ, LEONARDO M. FABBRI & CLAUDIO CECONI. (2012) Link between chronic obstructive pulmonary disease and coronary artery disease: Implication for clinical practice. Respirology 17:3, pages 422-431.
Crossref
Jonathan R. Enriquez & Elizabeth M. Holper. (2012) Increased Adverse Events After Percutaneous Coronary Intervention in Patients With COPD: Response. Chest 141:3, pages 829.
Crossref
Robert M. Reed & Steven Scharf. (2012) Increased Adverse Events After Percutaneous Coronary Intervention in Patients With COPD. Chest 141:3, pages 828-829.
Crossref
Thierry Troosters. 2012. Chronic Obstructive Pulmonary Disease. Chronic Obstructive Pulmonary Disease 47 59 .

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