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Articles: Critical Care

Blood concentrations are better predictors of chioroquine poisoning severity than plasma concentrations: a prospective study with modeling of the concentration/effect relationships

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Pages 904-915 | Received 17 Jul 2010, Accepted 24 Aug 2010, Published online: 17 Nov 2010

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Wouter Holvoet, Kaja van Soest, Thomas Havenith, Roberto Lorusso, Walther N. K. A. van Mook & Thijs Delnoij. (2021) Bail-out extracorporeal membrane oxygenation for hydroxychloroquine intoxication: a warning for COVID-19 health-care givers. Acta Cardiologica 76:2, pages 200-203.
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Cassandra Doyno, Diana M. Sobieraj & William L. Baker. (2021) Toxicity of chloroquine and hydroxychloroquine following therapeutic use or overdose. Clinical Toxicology 59:1, pages 12-23.
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Alexander Reisinger, Jasmin Rabensteiner & Gerald Hackl. (2020) Diagnosis of acute intoxications in critically ill patients: focus on biomarkers – part 2: markers for specific intoxications. Biomarkers 25:2, pages 112-125.
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Bruno Megarbane, Deborah Hirt, Vanessa Bloch & Frédéric J Baud. (2011) Epinephrine requirement based on the reported ingested dose in chloroquine poisoning: Usefulness and limitations of dose-effect modelling. Clinical Toxicology 49:3, pages 193-194.
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Articles from other publishers (18)

Priya Srihari, Alicia B. Minns, Han T. Gao & Allyson A. Kreshak. (2022) Massive Nonfatal Hydroxychloroquine Ingestion in a Pediatric Patient. The Journal of Emergency Medicine 62:3, pages 332-336.
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Sylvère Störmann, John Hoppe, Daniela Steinert & Matthias W. Angstwurm. (2022) A Case of Self-salvation in a Determined Chloroquine Suicide Attempt. The Journal of Critical Care Medicine 8:1, pages 61-65.
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Gongxin Wang, Chieh-Ju Lu, Andrew W. TraffordXiaohui Tian, Hannali M FloresPiotr MajKevin ZhangYanhong Niu, Luxi Wang, Yimei Du, Xinying Ji, Yanfang Xu, Lin Wu, Dan LiNeil HerringDavid PatersonChristopher L.-H. Huang, Henggui Zhang, Ming Lei & Guoliang Hao. (2021) Electrophysiological and Proarrhythmic Effects of Hydroxychloroquine Challenge in Guinea-Pig Hearts. ACS Pharmacology & Translational Science 4:5, pages 1639-1653.
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Dyfrig A. Hughes. (2020) Acute chloroquine poisoning: A comprehensive experimental toxicology assessment of the role of diazepam. British Journal of Pharmacology 177:21, pages 4975-4989.
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Ingrid Berling, Joshua D. King, Greene Shepherd, Robert S. Hoffman, Badria Alhatali, Valery Lavergne, Darren M. Roberts, Sophie Gosselin, Gabrielle Wilson, Thomas D. Nolin & Marc Ghannoum. (2020) Extracorporeal Treatment for Chloroquine, Hydroxychloroquine, and Quinine Poisoning: Systematic Review and Recommendations from the EXTRIP Workgroup. Journal of the American Society of Nephrology 31:10, pages 2475-2489.
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Alessandra Della Porta, Kasha Bornstein, Austin Coye, Tim Montrief, Brit Long & Mehruba Anwar Parris. (2020) Acute chloroquine and hydroxychloroquine toxicity: A review for emergency clinicians. The American Journal of Emergency Medicine 38:10, pages 2209-2217.
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Nicholas J. White, James A. Watson, Richard M. Hoglund, Xin Hui S. Chan, Phaik Yeong Cheah & Joel Tarning. (2020) COVID-19 prevention and treatment: A critical analysis of chloroquine and hydroxychloroquine clinical pharmacology. PLOS Medicine 17:9, pages e1003252.
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James A Watson, Joel Tarning, Richard M Hoglund, Frederic J Baud, Bruno Megarbane, Jean-Luc Clemessy & Nicholas J White. (2020) Concentration-dependent mortality of chloroquine in overdose. eLife 9.
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François Bagate, Costin Radu, Armand Mekontso Dessap & Nicolas de Prost. (2017) Early extracorporeal membrane oxygenation for cardiovascular failure in a patient with massive chloroquine poisoning. The American Journal of Emergency Medicine 35:2, pages 380.e3-380.e4.
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Alison L. Jones. 2017. Critical Care Toxicology. Critical Care Toxicology 1271 1286 .
Hephzibah Akpovwa. (2016) Chloroquine could be used for the treatment of filoviral infections and other viral infections that emerge or emerged from viruses requiring an acidic pH for infectivity. Cell Biochemistry and Function 34:4, pages 191-196.
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Rebecca E. Bruccoleri & Michele M. Burns. (2015) A Literature Review of the Use of Sodium Bicarbonate for the Treatment of QRS Widening. Journal of Medical Toxicology 12:1, pages 121-129.
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Alison L. Jones. 2016. Critical Care Toxicology. Critical Care Toxicology 1 16 .
Marion Soichot, Bruno Mégarbane, Pascal Houzé, Lucie Chevillard, Julien Fonsart, Frédéric J. Baud, Olivier Laprévote & Emmanuel Bourgogne. (2014) Development, validation and clinical application of a LC-MS/MS method for the simultaneous quantification of hydroxychloroquine and its active metabolites in human whole blood. Journal of Pharmaceutical and Biomedical Analysis 100, pages 131-137.
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Frédéric Baud, Philippe Hantson & Hafedh ThabetB. Mégarbane. 2013. Intoxications aiguës. Intoxications aiguës 97 115 .
S. Guillaume, S. Marien, P. M. François, A. Capron, P. Wallemacq & P. Hantson. (2012) Intoxication par la chloroquine : le traitement débute en préhospitalierChloroquine poisoning: priority to the prehospital management. Annales françaises de médecine d'urgence 2:6, pages 408-410.
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Albert Jaeger. (2012) Quinine and chloroquine. Medicine 40:3, pages 154-155.
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E. Dehours, A. Mari, P. Gandia, E. Montoro & D. Lauque. (2011) Défaillance cardiaque secondaire à une intoxication volontaire à la chloroquine : à propos d’un casHeart failure following chloroquine self-poisoning: a case report. Annales françaises de médecine d'urgence 1:5, pages 352-354.
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