721
Views
125
CrossRef citations to date
0
Altmetric
Original Article

An in vivo and in vitro toxicological characterisation of realistic nanoscale CeO2 inhalation exposures

, , , , , , , , , & show all
Pages 1338-1350 | Received 20 Jul 2012, Accepted 02 Oct 2012, Published online: 08 Nov 2012

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (22)

Niels Hadrup, Nicklas Sahlgren, Nicklas R. Jacobsen, Anne T. Saber, Karin S. Hougaard, Ulla Vogel & Keld A. Jensen. (2023) Toxicity dose descriptors from animal inhalation studies of 13 nanomaterials and their bulk and ionic counterparts and variation with primary particle characteristics. Nanotoxicology 17:4, pages 338-371.
Read now
Dadu Mal, Esra Alveroglu, Aamna Balouch, Muhammad Saqaf Jagirani, Abdullah & Sagar Kumar. (2022) Highly efficient and selective heterogeneous catalytic reduction of 2-nitroaniline by cerium oxide nanocatalyst under microwave irradiation. Environmental Technology 43:23, pages 3631-3645.
Read now
Pavitra Rajendran, Arunpandian Muthuraj & Nagarajan Erumaipatty Rajagounder. (2022) Review on CeO2-Based Corrosion Coatings. Transactions of the Indian Ceramic Society 81:4, pages 158-174.
Read now
Jing Yang, Jinzhe Zhou, Yingying Zhao, Liangchen Zhu, Guanghong Luo & BuJun Ge. (2021) Hollow CeO2 with ROS-Scavenging Activity to Alleviate Colitis in Mice. International Journal of Nanomedicine 16, pages 6889-6904.
Read now
Gemma Janer, Didem Ag-Seleci, Jacques-Aurélien Sergent, Robert Landsiedel & Wendel Wohlleben. (2021) Creating sets of similar nanoforms with the ECETOC NanoApp: real-life case studies. Nanotoxicology 15:8, pages 1016-1034.
Read now
Jutta Tentschert, Peter Laux, Harald Jungnickel, Josephine Brunner, Irina Estrela-Lopis, Carolin Merker, Jan Meijer, Heinrich Ernst, Lan Ma-Hock, Jana Keller, Robert Landsiedel & Andreas Luch. (2020) Organ burden of inhaled nanoceria in a 2-year low-dose exposure study: dump or depot?. Nanotoxicology 14:4, pages 554-576.
Read now
Chang Guo, Sarah Robertson, Ralf J. M. Weber, Alison Buckley, James Warren, Alan Hodgson, Joshua Z. Rappoport, Konstantin Ignatyev, Kirsty Meldrum, Isabella Römer, Sameirah Macchiarulo, James Kevin Chipman, Tim Marczylo, Martin O. Leonard, Timothy W. Gant, Mark R. Viant & Rachel Smith. (2019) Pulmonary toxicity of inhaled nano-sized cerium oxide aerosols in Sprague–Dawley rats. Nanotoxicology 13:6, pages 733-750.
Read now
Julia Catalán, Maria Luiza Fascineli, Nikolaos Politakos, Mira Hartikainen, Mônica Pereira Garcia, Paolin Rocio Cáceres-Vélez, Carlos Moreno, Sebastião Willian da Silva, Paulo César Morais, Hannu Norppa, Sergio E. Moya & Ricardo Bentes Azevedo. (2019) In vivo toxicological evaluation of polymer brush engineered nanoceria: impact of brush charge. Nanotoxicology 13:3, pages 305-325.
Read now
Ulrika Carlander, Tshepo Paulsen Moto, Anteneh Assefa Desalegn, Robert A Yokel & Gunnar Johanson. (2018) Physiologically based pharmacokinetic modeling of nanoceria systemic distribution in rats suggests dose- and route-dependent biokinetics. International Journal of Nanomedicine 13, pages 2631-2646.
Read now
Bing-Huei Chen & Baskaran Stephen Inbaraj. (2018) Various physicochemical and surface properties controlling the bioactivity of cerium oxide nanoparticles. Critical Reviews in Biotechnology 38:7, pages 1003-1024.
Read now
Sandra Vanessa Pirela, John Martin, Dhimiter Bello & Philip Demokritou. (2017) Nanoparticle exposures from nano-enabled toner-based printing equipment and human health: state of science and future research needs. Critical Reviews in Toxicology 47:8, pages 683-709.
Read now
Susan Dekkers, Mark R. Miller, Roel P. F. Schins, Isabella Römer, Mike Russ, Rob J. Vandebriel, Iseult Lynch, Marie-France Belinga-Desaunay, Eugenia Valsami-Jones, Shea P. Connell, Ian P. Smith, Rodger Duffin, John A. F. Boere, Harm J. Heusinkveld, Catrin Albrecht, Wim H. de Jong & Flemming R. Cassee. (2017) The effect of zirconium doping of cerium dioxide nanoparticles on pulmonary and cardiovascular toxicity and biodistribution in mice after inhalation. Nanotoxicology 11:6, pages 794-808.
Read now
Katherine M. Dunnick, Anna M. Morris, Melissa A. Badding, Mark Barger, Aleksandr B. Stefaniak, Edward M. Sabolsky & Stephen S. Leonard. (2016) Evaluation of the effect of valence state on cerium oxide nanoparticle toxicity following intratracheal instillation in rats. Nanotoxicology 10:7, pages 992-1000.
Read now
Nagarjun V. Konduru, Kimberly M. Murdaugh, Archana Swami, Renato J. Jimenez, Thomas C. Donaghey, Philip Demokritou, Joseph D. Brain & Ramon M. Molina. (2016) Surface modification of zinc oxide nanoparticles with amorphous silica alters their fate in the circulation. Nanotoxicology 10:6, pages 720-727.
Read now
Xiaoyan Lu, Isabelle R. Miousse, Sandra V. Pirela, Jodene K. Moore, Stepan Melnyk, Igor Koturbash & Philip Demokritou. (2016) In vivo epigenetic effects induced by engineered nanomaterials: A case study of copper oxide and laser printer-emitted engineered nanoparticles. Nanotoxicology 10:5, pages 629-639.
Read now
Danielle J. Botelho, Bey Fen Leo, Christopher B. Massa, Srijata Sarkar, Terry D. Tetley, Kian Fan Chung, Shu Chen, Mary P. Ryan, Alexandra E. Porter, Junfeng Zhang, Stephan K. Schwander & Andrew J. Gow. (2016) Low-dose AgNPs reduce lung mechanical function and innate immune defense in the absence of cellular toxicity. Nanotoxicology 10:1, pages 118-127.
Read now
Ali Kermanizadeh, Ilse Gosens, Laura MacCalman, Helinor Johnston, Pernille H. Danielsen, Nicklas R. Jacobsen, Anke-Gabriele Lenz, Teresa Fernandes, Roel P. F. Schins, Flemming R. Cassee, Håkan Wallin, Wolfgang Kreyling, Tobias Stoeger, Steffen Loft, Peter Møller, Lang Tran & Vicki Stone. (2016) A Multilaboratory Toxicological Assessment of a Panel of 10 Engineered Nanomaterials to Human Health—ENPRA Project—The Highlights, Limitations, and Current and Future Challenges. Journal of Toxicology and Environmental Health, Part B 19:1, pages 1-28.
Read now
Anoop K. Pal, Dhimiter Bello, Joel Cohen & Philip Demokritou. (2015) Implications of in vitro dosimetry on toxicological ranking of low aspect ratio engineered nanomaterials. Nanotoxicology 9:7, pages 871-885.
Read now
Jennifer D. Sisler, Sandra V. Pirela, Sherri Friend, Mariana Farcas, Diane Schwegler-Berry, Anna Shvedova, Vincent Castranova, Philip Demokritou & Yong Qian. (2015) Small airway epithelial cells exposure to printer-emitted engineered nanoparticles induces cellular effects on human microvascular endothelial cells in an alveolar-capillary co-culture model. Nanotoxicology 9:6, pages 769-779.
Read now
Sandra V. Pirela, Georgios A. Sotiriou, Dhimiter Bello, Martin Shafer, Kristin Lee Bunker, Vincent Castranova, Treye Thomas & Philip Demokritou. (2015) Consumer exposures to laser printer-emitted engineered nanoparticles: A case study of life-cycle implications from nano-enabled products. Nanotoxicology 9:6, pages 760-768.
Read now
Joel M. Cohen, Raymond Derk, Liying Wang, John Godleski, Lester Kobzik, Joseph Brain & Philip Demokritou. (2014) Tracking translocation of industrially relevant engineered nanomaterials (ENMs) across alveolar epithelial monolayers in vitro. Nanotoxicology 8:sup1, pages 216-225.
Read now
Sandra V. Pirela, Georgios Pyrgiotakis, Dhimiter Bello, Treye Thomas, Vincent Castranova & Philip Demokritou. (2014) Development and characterization of an exposure platform suitable for physico-chemical, morphological and toxicological characterization of printer-emitted particles (PEPs). Inhalation Toxicology 26:7, pages 400-408.
Read now

Articles from other publishers (103)

Jingxuan Lu, Jingwen Luo, Jie Li, Shiyan Fu, Yonghong Ran, Juan Li, Yazhen Zhao & Yuhui Hao. (2023) Fluorescent Pirfenidone-Cerium(III) nanocomplexes protect against radiation-induced pulmonary fibrosis and inhibit tumor cell growth. Journal of Drug Delivery Science and Technology 86, pages 104651.
Crossref
Benjamin D. Trump, Dalila Antunes, José Palma-Oliveira, Andrew Nelson, Alexandra Misci Hudecova, Elise Rundén-Pran, Maria Dusinska, Ignasi Gispert, Susanne Resch, Beatriz Alfaro-Serrano, Antreas Afantitis, Georgia Melagraki, Edmund C. M. Tse, Josh Trump, Yvonne Kohl & Igor Linkov. (2023) Safety-by-design and engineered nanomaterials: the need to move from theory to practice. Environment Systems and Decisions.
Crossref
Francesca Corsi, Erika Di Meo, Daniela Lulli, Greta Deidda Tarquini, Francesco Capradossi, Emanuele Bruni, Andrea Pelliccia, Enrico Traversa, Elena Dellambra, Cristina Maria Failla & Lina Ghibelli. (2023) Safe-Shields: Basal and Anti-UV Protection of Human Keratinocytes by Redox-Active Cerium Oxide Nanoparticles Prevents UVB-Induced Mutagenesis. Antioxidants 12:3, pages 757.
Crossref
Kai Li & Xiaoqing Luo. (2023) Research Progress on Catalytic Combustion of Volatile Organic Compounds in Industrial Waste Gas. Catalysts 13:2, pages 268.
Crossref
Anas Ahmad, Mohammad Imran & Nisha Sharma. (2022) Precision Nanotoxicology in Drug Development: Current Trends and Challenges in Safety and Toxicity Implications of Customized Multifunctional Nanocarriers for Drug-Delivery Applications. Pharmaceutics 14:11, pages 2463.
Crossref
Peng Liu, Ying Peng, Jinsong Ding & Wenhu Zhou. (2022) Fenton metal nanomedicines for imaging-guided combinatorial chemodynamic therapy against cancer. Asian Journal of Pharmaceutical Sciences 17:2, pages 177-192.
Crossref
Wells Utembe & Natasha Sanabria. (2022) Lung Dosimetry Modelling in Nanotoxicology: A Critical Analysis of the State of the Art. Lung Dosimetry Modelling in Nanotoxicology: A Critical Analysis of the State of the Art.
Daina Romeo, Bernd Nowack & Peter Wick. (2022) Combined in vitro-in vivo dosimetry enables the extrapolation of in vitro doses to human exposure levels: A proof of concept based on a meta-analysis of in vitro and in vivo titanium dioxide toxicity data. NanoImpact 25, pages 100376.
Crossref
Antonella Camaioni, Micol Massimiani, Valentina Lacconi, Andrea Magrini, Antonietta Salustri, Georgios A. Sotiriou, Dilpreet Singh, Dimitrios Bitounis, Beatrice Bocca, Anna Pino, Flavia Barone, Valentina Prota, Ivo Iavicoli, Manuel Scimeca, Elena Bonanno, Flemming R. Cassee, Philip Demokritou, Antonio Pietroiusti & Luisa Campagnolo. (2021) Silica encapsulation of ZnO nanoparticles reduces their toxicity for cumulus cell-oocyte-complex expansion. Particle and Fibre Toxicology 18:1.
Crossref
Maria João Bessa, Fátima Brandão, Paul H. B. Fokkens, Daan L. A. C. Leseman, A. John F. Boere, Flemming R. Cassee, Apostolos Salmatonidis, Mar Viana, Adriana Vulpoi, Simion Simon, Eliseo Monfort, João Paulo Teixeira & Sónia Fraga. (2021) In Vitro Toxicity of Industrially Relevant Engineered Nanoparticles in Human Alveolar Epithelial Cells: Air–Liquid Interface versus Submerged Cultures. Nanomaterials 11:12, pages 3225.
Crossref
Shuoshuo Yang, Jiale Ji, Mengwei Luo, Hailing Li & Zhonghong Gao. (2021) Poly(tannic acid) nanocoating based surface modification for construction of multifunctional composite CeO 2 NZs to enhance cell proliferation and antioxidative viability of preosteoblasts . Nanoscale 13:38, pages 16349-16361.
Crossref
Changjian Xie, Yuhui Ma, Peng Zhang, Junzhe Zhang, Xiaowei Li, Kang Zheng, Ao Li, Weiwei Wu, Qiuxiang Pang, Xiao He & Zhiyong Zhang. (2021) Elucidating the origin of the toxicity of nano-CeO 2 to Chlorella pyrenoidosa : the role of specific surface area and chemical composition . Environmental Science: Nano 8:6, pages 1701-1712.
Crossref
Katherine E. Burns, Robert F. Uhrig, Maggie E. Jewett, Madison F. Bourbon & Kristen A. Krupa. (2021) Characterizing the Role of Biologically Relevant Fluid Dynamics on Silver Nanoparticle Dependent Oxidative Stress in Adherent and Suspension In Vitro Models. Antioxidants 10:6, pages 832.
Crossref
Chang Guo, Ralf J. M. Weber, Alison Buckley, Julie Mazzolini, Sarah Robertson, Juana Maria Delgado-Saborit, Joshua Z. Rappoport, James Warren, Alan Hodgson, Paul Sanderson, James Kevin Chipman, Mark R. Viant & Rachel Smith. (2021) Environmentally Relevant Iron Oxide Nanoparticles Produce Limited Acute Pulmonary Effects in Rats at Realistic Exposure Levels. International Journal of Molecular Sciences 22:2, pages 556.
Crossref
Muhammad Moazzam Latif, Anwar-ul- Haq, Faheem Amin, Muhammad Ajaz-un-Nabi, Ikram-ullha Khan & Nadeem Sabir. (2021) Synthesis and antimicrobial activities of Manganese (Mn) and iron (Fe) co-doped Cerium dioxide (CeO2) Nanoparticles. Physica B: Condensed Matter 600, pages 412562.
Crossref
Silvia Diabaté, Lucie Armand, Sivakumar Murugadoss, Marco Dilger, Susanne Fritsch-Decker, Christoph Schlager, David Béal, Marie-Edith Arnal, Mathilde Biola-Clier, Selina Ambrose, Sonja Mülhopt, Hanns-Rudolf Paur, Iseult Lynch, Eugenia Valsami-Jones, Marie Carriere & Carsten Weiss. (2020) Air–Liquid Interface Exposure of Lung Epithelial Cells to Low Doses of Nanoparticles to Assess Pulmonary Adverse Effects. Nanomaterials 11:1, pages 65.
Crossref
Lars Leibrock, Harald Jungnickel, Jutta Tentschert, Aaron Katz, Blaza Toman, Elijah Petersen, Frank Bierkandt, Ajay Singh, Peter Laux & Andreas Luch. (2020) Parametric Optimization of an Air–Liquid Interface System for Flow-Through Inhalation Exposure to Nanoparticles: Assessing Dosimetry and Intracellular Uptake of CeO2 Nanoparticles. Nanomaterials 10:12, pages 2369.
Crossref
Tina Wahle, Adriana Sofranko, Susan Dekkers, Mark R. Miller, Harm J. Heusinkveld, Catrin Albrecht, Flemming R. Cassee & Roel P.F. Schins. (2020) Evaluation of neurological effects of cerium dioxide nanoparticles doped with different amounts of zirconium following inhalation exposure in mouse models of Alzheimer's and vascular disease. Neurochemistry International 138, pages 104755.
Crossref
Dadu Mal, Aamna Balouch, Sirajuddin, Abdullah, Ali Muhammad Mahar, Abdul Hameed Pato, Sagar Kumar, Shanker Lal & Aneel Kumar. (2020) Synthesis and catalytic practicality of CeO2 nanoparticle: an excellent heterogenous candidate for 4-nitrophenol reduction. Applied Nanoscience 10:9, pages 3443-3455.
Crossref
Maram Bakiro, Salwa Hussein Ahmed & Ahmed Alzamly. (2020) Investigation of the band gap energy shift and photocatalytic properties of Bi3+-doped ceria. Inorganic Chemistry Communications 116, pages 107906.
Crossref
Hasnain Jan, Muhammad Aslam Khan, Hazrat Usman, Muzamil Shah, Rotaba Ansir, Shah Faisal, Niamat Ullah & Lubna Rahman. (2020) The Aquilegia pubiflora (Himalayan columbine) mediated synthesis of nanoceria for diverse biomedical applications . RSC Advances 10:33, pages 19219-19231.
Crossref
Blakely B O’Connor, Thomas Grevesse, John F Zimmerman, Herdeline Ann M Ardoña, Jorge A Jimenez, Dimitrios Bitounis, Philip Demokritou & Kevin Kit Parker. (2020) Human brain microvascular endothelial cell pairs model tissue-level blood–brain barrier function. Integrative Biology 12:3, pages 64-79.
Crossref
Hamza E Ahmed Mohamed, Shakeeb Afridi, Ali T Khalil, Muhammad Ali, Tanzeel Zohra, Ribqa Akhtar, Aamer Ikram, Zabta K Shinwari & Malik Maaza. (2020) Promising antiviral, antimicrobial and therapeutic properties of green nanoceria. Nanomedicine 15:5, pages 467-488.
Crossref
Kirsty Meldrum, Sarah Robertson, Isabella Römer, Tim Marczylo, Timothy W. Gant, Rachel Smith, Teresa D. Tetley & Martin O. Leonard. (2020) Diesel exhaust particle and dust mite induced airway inflammation is modified by cerium dioxide nanoparticles. Environmental Toxicology and Pharmacology 73, pages 103273.
Crossref
Victoria Oluwaseun Fasiku, Shesan John Owonubi, Nyemaga Masanje Malima, Daniel Hassan & Neerish Revaprasadu. 2020. Antibiotic Materials in Healthcare. Antibiotic Materials in Healthcare 261 286 .
Susheel Kumar Nethi, Vishnu Sravan Bollu, Neeraja Aparna Anand P.Chitta Ranjan Patra. 2020. Nanoparticles and their Biomedical Applications. Nanoparticles and their Biomedical Applications 1 43 .
Guoxiang You, Jun Hou, Yi Xu, Lingzhan Miao, Yanhui Ao & Baoshan Xing. 2021. Reviews of Environmental Contamination and Toxicology Volume 253. Reviews of Environmental Contamination and Toxicology Volume 253 155 206 .
Nancy Lan Guo, Tuang Yeow Poh, Sandra Pirela, Mariana T. Farcas, Sanjay H. Chotirmall, Wai Kin Tham, Sunil S. Adav, Qing Ye, Yongyue Wei, Sipeng Shen, David C. Christiani, Kee Woei Ng, Treye Thomas, Yong Qian & Philip Demokritou. (2019) Integrated Transcriptomics, Metabolomics, and Lipidomics Profiling in Rat Lung, Blood, and Serum for Assessment of Laser Printer-Emitted Nanoparticle Inhalation Exposure-Induced Disease Risks. International Journal of Molecular Sciences 20:24, pages 6348.
Crossref
Tiffany G. Kornberg, Todd A. Stueckle, Jayme Coyle, Raymond Derk, Philip Demokritou, Yon Rojanasakul & Liying W. Rojanasakul. (2019) Iron Oxide Nanoparticle-Induced Neoplastic-Like Cell Transformation in Vitro Is Reduced with a Protective Amorphous Silica Coating . Chemical Research in Toxicology 32:12, pages 2382-2397.
Crossref
Gunugunuri K. Reddy, Torin C. Peck & Charles A. Roberts. (2019) CeO 2 –M x O y (M = Fe, Co, Ni, and Cu)-Based Oxides for Direct NO Decomposition . The Journal of Physical Chemistry C 123:47, pages 28695-28706.
Crossref
Lars Leibrock, Sandra Wagener, Ajay Vikram Singh, Peter Laux & Andreas Luch. (2019) Nanoparticle induced barrier function assessment at liquid–liquid and air–liquid interface in novel human lung epithelia cell lines. Toxicology Research 8:6, pages 1016-1027.
Crossref
Beibei Chen, Judy Tsz-Shan Lum, Yingyan Huang, Bin Hu & Kelvin Sze-Yin Leung. (2019) Integration of sub-organ quantitative imaging LA-ICP-MS and fractionation reveals differences in translocation and transformation of CeO2 and Ce3+ in mice. Analytica Chimica Acta 1082, pages 18-29.
Crossref
Qiuhan Hua, Yingnan Chen, Yufei Liu, Meizhen Li, Qinqin Diao, Hainan Xue, Huixian Zeng, Lihua Huang & Yiguo Jiang. (2019) Circular RNA 0039411 Is Involved in Neodymium Oxide-induced Inflammation and Antiproliferation in a Human Bronchial Epithelial Cell Line via Sponging miR-93-5p. Toxicological Sciences 170:1, pages 69-81.
Crossref
Nachiket Vaze, Georgios Pyrgiotakis, James McDevitt, Lucas Mena, Adler Melo, Alice Bedugnis, Lester Kobzik, Mary Eleftheriadou & Philip Demokritou. (2019) Inactivation of common hospital acquired pathogens on surfaces and in air utilizing engineered water nanostructures (EWNS) based nano-sanitizers. Nanomedicine: Nanotechnology, Biology and Medicine 18, pages 234-242.
Crossref
Kirk T. Kitchin, Judy A. Richards, Brian L. Robinette, Kathleen A. Wallace, Najwa H. Coates, Benjamin T. Castellon & Eric A. Grulke. (2018) Biochemical effects of some CeO2, SiO2, and TiO2 nanomaterials in HepG2 cells. Cell Biology and Toxicology 35:2, pages 129-145.
Crossref
Jiayuan Zhao, Guillaume Suárez, Ngoc Tran, Victor Puntes & Michael Riediker. (2019) Coating aerosolized nanoparticles with low-volatile organic compound (LVOC) vapors modifies surface functionality and oxidative reactivity. NanoImpact 14, pages 100150.
Crossref
Changjian Xie, Junzhe Zhang, Yuhui Ma, Yayun Ding, Peng Zhang, Lirong Zheng, Zhifang Chai, Yuliang Zhao, Zhiyong Zhang & Xiao He. (2019) Bacillus subtilis causes dissolution of ceria nanoparticles at the nano–bio interface . Environmental Science: Nano 6:1, pages 216-223.
Crossref
Dilpreet Singh, Wendel Wohlleben, Roberto De La Torre Roche, Jason C. White & Philip Demokritou. (2019) Thermal decomposition/incineration of nano-enabled coatings and effects of nanofiller/matrix properties and operational conditions on byproduct release dynamics: Potential environmental health implications. NanoImpact 13, pages 44-55.
Crossref
Kirsty Meldrum, Sarah B. Robertson, Isabella Römer, Tim Marczylo, Lareb S. N. Dean, Andrew Rogers, Timothy W. Gant, Rachel Smith, Terry D. Tetley & Martin O. Leonard. (2018) Cerium dioxide nanoparticles exacerbate house dust mite induced type II airway inflammation. Particle and Fibre Toxicology 15:1.
Crossref
Thomas Loret, Françoise Rogerieux, Bénédicte Trouiller, Anne Braun, Christophe Egles & Ghislaine Lacroix. (2018) Predicting the in vivo pulmonary toxicity induced by acute exposure to poorly soluble nanomaterials by using advanced in vitro methods. Particle and Fibre Toxicology 15:1.
Crossref
Dennis G. Thomas, Jordan N. Smith, Brian D. Thrall, Donald R. Baer, Hadley Jolley, Prabhakaran Munusamy, Vamsi Kodali, Philip Demokritou, Joel Cohen & Justin G. Teeguarden. (2018) ISD3: a particokinetic model for predicting the combined effects of particle sedimentation, diffusion and dissolution on cellular dosimetry for in vitro systems. Particle and Fibre Toxicology 15:1.
Crossref
Daniela Schwotzer, Monika Niehof, Dirk Schaudien, Heiko Kock, Tanja Hansen, Clemens Dasenbrock & Otto Creutzenberg. (2018) Cerium oxide and barium sulfate nanoparticle inhalation affects gene expression in alveolar epithelial cells type II. Journal of Nanobiotechnology 16:1.
Crossref
Kuan-Jen Bai, Kai-Jen Chuang, Jen-Kun Chen, His-En Hua, Yen-Ling Shen, Wei-Neng Liao, Chii-Hong Lee, Kuan-Yuan Chen, Kang-Yun Lee, Ta-Chih Hsiao, Chih-Hong Pan, Kin-Fai Ho & Hsiao-Chi Chuang. (2018) Investigation into the pulmonary inflammopathology of exposure to nickel oxide nanoparticles in mice. Nanomedicine: Nanotechnology, Biology and Medicine 14:7, pages 2329-2339.
Crossref
Atul Dhall & William Self. (2018) Cerium Oxide Nanoparticles: A Brief Review of Their Synthesis Methods and Biomedical Applications. Antioxidants 7:8, pages 97.
Crossref
Emily K Breitner, Katherine E Burns, Saber M Hussain & Kristen K Comfort. (2018) Implementation of physiological fluids to provide insight into the characterization, fate, and biological interactions of silver nanoparticles. Nanotechnology 29:25, pages 254001.
Crossref
Qian Zhang, Weien Lai, Ting Yin, Chunlei Zhang, Caixia Yue, Jin Cheng, Kan Wang, Yuming Yang, Daxiang Cui & Wolfgang J. Parak. (2018) Investigation of the Viability of Cells upon Co-Exposure to Gold and Iron Oxide Nanoparticles. Bioconjugate Chemistry 29:6, pages 2120-2125.
Crossref
Frank S. Bierkandt, Lars Leibrock, Sandra Wagener, Peter Laux & Andreas Luch. (2018) The impact of nanomaterial characteristics on inhalation toxicity. Toxicology Research 7:3, pages 321-346.
Crossref
O. A. Adebayo, O. Akinloye & O. A. Adaramoye. (2018) Cerium oxide nanoparticle elicits oxidative stress, endocrine imbalance and lowers sperm characteristics in testes of balb/c mice. Andrologia 50:3, pages e12920.
Crossref
Juan Beltran-Huarac, Zhenyuan Zhang, Georgios Pyrgiotakis, Glen DeLoid, Nachiket Vaze & Philip Demokritou. (2018) Development of reference metal and metal oxide engineered nanomaterials for nanotoxicology research using high throughput and precision flame spray synthesis approaches. NanoImpact 10, pages 26-37.
Crossref
S. Rajeshkumar & Poonam Naik. (2018) Synthesis and biomedical applications of Cerium oxide nanoparticles – A Review. Biotechnology Reports 17, pages 1-5.
Crossref
M. Zarezadeh Mehrizi, S. Ahmadi, R. Beygi & M. Asadi. (2018) Fabrication of Cerium Oxide Nanoparticles by Solution Combustion Synthesis and Their Cytotoxicity Evaluation. Russian Journal of Non-Ferrous Metals 59:1, pages 111-116.
Crossref
Peter Laux, Jutta Tentschert, Christian Riebeling, Albert Braeuning, Otto Creutzenberg, Astrid Epp, Valérie Fessard, Karl-Heinz Haas, Andrea Haase, Kerstin Hund-Rinke, Norbert Jakubowski, Peter Kearns, Alfonso Lampen, Hubert Rauscher, Reinhilde Schoonjans, Angela Störmer, Axel Thielmann, Uwe Mühle & Andreas Luch. (2017) Nanomaterials: certain aspects of application, risk assessment and risk communication. Archives of Toxicology 92:1, pages 121-141.
Crossref
Kizhaeral S. Subramanian & S. K. Rajkishore. 2018. Nanomaterials: Ecotoxicity, Safety, and Public Perception. Nanomaterials: Ecotoxicity, Safety, and Public Perception 319 342 .
Nagarjun V. Konduru, Ramon M. Molina, Archana Swami, Flavia Damiani, Georgios Pyrgiotakis, Paulo Lin, Patrizia Andreozzi, Thomas C. Donaghey, Philip Demokritou, Silke Krol, Wolfgang Kreyling & Joseph D. Brain. (2017) Protein corona: implications for nanoparticle interactions with pulmonary cells. Particle and Fibre Toxicology 14:1.
Crossref
Daniela Schwotzer, Heinrich Ernst, Dirk Schaudien, Heiko Kock, Gerhard Pohlmann, Clemens Dasenbrock & Otto Creutzenberg. (2017) Effects from a 90-day inhalation toxicity study with cerium oxide and barium sulfate nanoparticles in rats. Particle and Fibre Toxicology 14:1.
Crossref
Dilpreet Singh, Laura Arabella Schifman, Christa Watson-Wright, Georgios A. Sotiriou, Vinka Oyanedel-Craver, Wendel Wohlleben & Philip Demokritou. (2017) Nanofiller Presence Enhances Polycyclic Aromatic Hydrocarbon (PAH) Profile on Nanoparticles Released during Thermal Decomposition of Nano-enabled Thermoplastics: Potential Environmental Health Implications. Environmental Science & Technology 51:9, pages 5222-5232.
Crossref
Mohammad Fatouraie, W. Ethan Eagle, Dingsheng Li, Masako Morishita, James Barres, James G. Wagner, Olivier Jolliet & Margaret S. Wooldridge. (2017) Combustion synthesis of CeO 2 nanoparticles for aging and inhalation exposure studies. Journal of Aerosol Science 106, pages 24-33.
Crossref
Todd A. Stueckle, Donna C. Davidson, Raymond Derk, Tiffany G. Kornberg, Diane Schwegler-Berry, Sandra V. Pirela, Glen Deloid, Philip Demokritou, Sudjit Luanpitpong, Yon Rojanasakul & Liying Wang. (2017) Evaluation of tumorigenic potential of CeO2 and Fe2O3 engineered nanoparticles by a human cell in vitro screening model. NanoImpact 6, pages 39-54.
Crossref
Soumen Das, Philip Reed McDonagh, Tamil Selvan Sakthivel, Swetha Barkam, Kelsey Killion, Julian Ortiz, Shashank Saraf, Amit Kumar, Ankur Gupta, Jamal Zweit & Sudipta Seal. (2017) Tissue deposition and toxicological effects of commercially significant rare earth oxide nanomaterials: Material and physical properties. Environmental Toxicology 32:3, pages 904-917.
Crossref
Glen M DeLoid, Joel M Cohen, Georgios Pyrgiotakis & Philip Demokritou. (2017) Preparation, characterization, and in vitro dosimetry of dispersed, engineered nanomaterials. Nature Protocols 12:2, pages 355-371.
Crossref
Valérie Forest, Lara Leclerc, Jean-François Hochepied, Adeline Trouvé, Gwendoline Sarry & Jérémie Pourchez. (2017) Impact of cerium oxide nanoparticles shape on their in vitro cellular toxicity. Toxicology in Vitro 38, pages 136-141.
Crossref
Inese Kokina, Inese Jahundoviča, Ilona Mickeviča, Marija Jermaļonoka, Jānis Strautiņš, Sergejs Popovs, Andrejs Ogurcovs, Eriks Sledevskis, Boriss Polyakov & Vjačeslavs Gerbreders. (2017) Target Transportation of Auxin on Mesoporous Au/SiO 2 Nanoparticles as a Method for Somaclonal Variation Increasing in Flax ( L. usitatissimum L.) . Journal of Nanomaterials 2017, pages 1-9.
Crossref
N. Shandilya & I. Capron. (2017) Safer-by-design hybrid nanostructures: an alternative to conventional titanium dioxide UV filters in skin care products. RSC Advances 7:33, pages 20430-20439.
Crossref
Marie-Cecile G. Chalbot, Sandra V. Pirela, Laura Schifman, Varun Kasaraneni, Vinka Oyanedel-Craver, Dhimiter Bello, Vincent Castranova, Yong Qian, Treye Thomas, Ilias G. Kavouras & Philip Demokritou. (2017) Synergistic effects of engineered nanoparticles and organics released from laser printers using nano-enabled toners: potential health implications from exposures to the emitted organic aerosol. Environmental Science: Nano 4:11, pages 2144-2156.
Crossref
Kai Wang, Xiaoqing He, Will Linthicum, Ryan Mezan, Liying Wang, Yon Rojanasakul, Qi Wen & Yong Yang. (2017) Carbon nanotubes induced fibrogenesis on nanostructured substrates. Environ. Sci.: Nano 4:3, pages 689-699.
Crossref
Thomas Loret, Emmanuel Peyret, Marielle Dubreuil, Olivier Aguerre-Chariol, Christophe Bressot, Olivier le Bihan, Tanguy Amodeo, Bénédicte Trouiller, Anne Braun, Christophe Egles & Ghislaine Lacroix. (2016) Air-liquid interface exposure to aerosols of poorly soluble nanomaterials induces different biological activation levels compared to exposure to suspensions. Particle and Fibre Toxicology 13:1.
Crossref
C. Y. Watson, G. M. DeLoid, A. Pal & P. Demokritou. (2016) Buoyant Nanoparticles: Implications for Nano-Biointeractions in Cellular Studies. Small 12:23, pages 3172-3180.
Crossref
Glen DeLoid, Beatriz Casella, Sandra Pirela, Rose Filoramo, Georgios Pyrgiotakis, Philip Demokritou & Lester Kobzik. (2016) Effects of engineered nanomaterial exposure on macrophage innate immune function. NanoImpact 2, pages 70-81.
Crossref
Nuray Gunduz, Elif Arslan, Mustafa O. Guler & Ayse B. Tekinay. 2016. Therapeutic Nanomaterials. Therapeutic Nanomaterials 271 298 .
Georgios A. Sotiriou, Dilpreet Singh, Fang Zhang, Marie-Cecile G. Chalbot, Eleanor Spielman-Sun, Lutz Hoering, Ilias G. Kavouras, Gregory V. Lowry, Wendel Wohlleben & Philip Demokritou. (2016) Thermal decomposition of nano-enabled thermoplastics: Possible environmental health and safety implications. Journal of Hazardous Materials 305, pages 87-95.
Crossref
Sandra V. Pirela, Isabelle R. Miousse, Xiaoyan Lu, Vincent Castranova, Treye Thomas, Yong Qian, Dhimiter Bello, Lester Kobzik, Igor Koturbash & Philip Demokritou. (2016) Effects of Laser Printer–Emitted Engineered Nanoparticles on Cytotoxicity, Chemokine Expression, Reactive Oxygen Species, DNA Methylation, and DNA Damage: A Comprehensive in Vitro Analysis in Human Small Airway Epithelial Cells, Macrophages, and Lymphoblasts . Environmental Health Perspectives 124:2, pages 210-219.
Crossref
Kristen K. Comfort. (2016) The rise of nanotoxicology: A successful collaboration between engineering and biology. AIMS Bioengineering 3:3, pages 230-244.
Crossref
Dilpreet Singh, Georgios A. Sotiriou, Fang Zhang, Joey Mead, Dhimiter Bello, Wendel Wohlleben & Philip Demokritou. (2016) End-of-life thermal decomposition of nano-enabled polymers: effect of nanofiller loading and polymer matrix on by-products. Environmental Science: Nano 3:6, pages 1293-1305.
Crossref
J. Gagnon, M. J. D. Clift, D. Vanhecke, I. E. Widnersson, S.-L. Abram, A. Petri-Fink, R. A. Caruso, B. Rothen-Rutishauser & K. M. Fromm. (2016) Synthesis, characterization, antibacterial activity and cytotoxicity of hollow TiO 2 -coated CeO 2 nanocontainers encapsulating silver nanoparticles for controlled silver release . Journal of Materials Chemistry B 4:6, pages 1166-1174.
Crossref
Vicki H. Grassian, Amanda J. Haes, Imali A. Mudunkotuwa, Philip Demokritou, Agnes B. Kane, Catherine J. Murphy, James E. Hutchison, Jacqueline A. Isaacs, Young-Shin Jun, Barbara Karn, Saiful I. Khondaker, Sarah C. Larsen, Boris L. T. Lau, John M. Pettibone, Omowunmi A. Sadik, Navid B. Saleh & Clayton Teague. (2016) NanoEHS – defining fundamental science needs: no easy feat when the simple itself is complex. Environmental Science: Nano 3:1, pages 15-27.
Crossref
Dingsheng Li, Masako Morishita, James G. Wagner, Mohammad Fatouraie, Margaret Wooldridge, W. Ethan Eagle, James Barres, Ulrika Carlander, Claude Emond & Olivier Jolliet. (2016) In vivo biodistribution and physiologically based pharmacokinetic modeling of inhaled fresh and aged cerium oxide nanoparticles in rats. Particle and Fibre Toxicology 13:1.
Crossref
Donna C. Davidson, Raymond Derk, Xiaoqing He, Todd A. Stueckle, Joel Cohen, Sandra V. Pirela, Philip Demokritou, Yon Rojanasakul & Liying Wang. (2016) Direct stimulation of human fibroblasts by nCeO2 in vitro is attenuated with an amorphous silica coating. Particle and Fibre Toxicology 13:1.
Crossref
Glen M. DeLoid, Joel M. Cohen, Georgios Pyrgiotakis, Sandra V. Pirela, Anoop Pal, Jiying Liu, Jelena Srebric & Philip Demokritou. (2015) Advanced computational modeling for in vitro nanomaterial dosimetry. Particle and Fibre Toxicology 12:1.
Crossref
Nagarjun V. Konduru, Renato J. Jimenez, Archana Swami, Sherri Friend, Vincent Castranova, Philip Demokritou, Joseph D. Brain & Ramon M. Molina. (2015) Silica coating influences the corona and biokinetics of cerium oxide nanoparticles. Particle and Fibre Toxicology 12:1.
Crossref
John Martin, Dhimiter Bello, Kristin Bunker, Martin Shafer, David Christiani, Susan Woskie & Philip Demokritou. (2015) Occupational exposure to nanoparticles at commercial photocopy centers. Journal of Hazardous Materials 298, pages 351-360.
Crossref
Joel M Cohen, Glen M DeLoid & Philip Demokritou. (2015) A critical review of in vitro dosimetry for engineered nanomaterials . Nanomedicine 10:19, pages 3015-3032.
Crossref
Jane Ma, Robert R. Mercer, Mark Barger, Diane Schwegler-Berry, Joel M. Cohen, Philip Demokritou & Vincent Castranova. (2015) Effects of amorphous silica coating on cerium oxide nanoparticles induced pulmonary responses. Toxicology and Applied Pharmacology 288:1, pages 63-73.
Crossref
Esther Belade, Sandra Chrusciel, Lucie Armand, Angélique Simon-Deckers, Cyrill Bussy, Philippe Caramelle, Jean-Marie Gagliolo, Laurent Boyer, Sophie Lanone, Jean-Claude Pairon, Ali Kermanizadeh & Jorge Boczkowski. (2014) The role of p53 in lung macrophages following exposure to a panel of manufactured nanomaterials. Archives of Toxicology 89:9, pages 1543-1556.
Crossref
Anoop K. Pal, Christa Y. Watson, Sandra V. Pirela, Dilpreet Singh, Marie-Cecile G. Chalbot, Ilias Kavouras & Philip Demokritou. (2015) Linking Exposures of Particles Released From Nano-Enabled Products to Toxicology: An Integrated Methodology for Particle Sampling, Extraction, Dispersion, and Dosing. Toxicological Sciences 146:2, pages 321-333.
Crossref
Katherine M. Dunnick, Rajalekshmi Pillai, Kelly L. Pisane, Aleksandr B. Stefaniak, Edward M. Sabolsky & Stephen S. Leonard. (2015) The Effect of Cerium Oxide Nanoparticle Valence State on Reactive Oxygen Species and Toxicity. Biological Trace Element Research 166:1, pages 96-107.
Crossref
Nan Chen, Peter Kovacik, Rachel M. Howden, Xiaoxue Wang, Sunghwan Lee & Karen K. Gleason. (2015) Low Substrate Temperature Encapsulation for Flexible Electrodes and Organic Photovoltaics. Advanced Energy Materials 5:6, pages 1401442.
Crossref
Georgios A. Sotiriou, Dilpreet Singh, Fang Zhang, Wendel Wohlleben, Marie-Cecile G. Chalbot, Ilias G. Kavouras & Philip Demokritou. (2015) An integrated methodology for the assessment of environmental health implications during thermal decomposition of nano-enabled products. Environmental Science: Nano 2:3, pages 262-272.
Crossref
Enhua H ZhouChrista Watson, Richard PizzoJoel Cohen, Quynh Dang, Pedro Macul Ferreira de Barros, Chan Young Park, Cheng Chen, Joseph D Brain, James P Butler, Jeffrey W Ruberti, Jeffrey J Fredberg & Philip Demokritou. (2014) Assessing the impact of engineered nanoparticles on wound healing using a novel in vitro bioassay . Nanomedicine 9:18, pages 2803-2815.
Crossref
Olimpia Gamucci & Giuseppe Bardi. (2014) Cerium dioxide nanoparticles selectively up-regulate C-C chemokine receptor 2 and CD16 expression on human monocytes. EURO-NanoTox-Letters 5:1, pages 1-16.
Crossref
Nagarjun V Konduru, Kimberly M Murdaugh, Georgios A Sotiriou, Thomas C Donaghey, Philip Demokritou, Joseph D Brain & Ramon M Molina. (2014) Bioavailability, distribution and clearance of tracheally-instilled and gavaged uncoated or silica-coated zinc oxide nanoparticles. Particle and Fibre Toxicology 11:1.
Crossref
Joel M Cohen, Justin G Teeguarden & Philip Demokritou. (2014) An integrated approach for the in vitro dosimetry of engineered nanomaterials. Particle and Fibre Toxicology 11:1.
Crossref
Thomas Gebel, Heidi Foth, Georg Damm, Alexius Freyberger, Peter-Jürgen Kramer, Werner Lilienblum, Claudia Röhl, Thomas Schupp, Carsten Weiss, Klaus-Michael Wollin & Jan Georg Hengstler. (2014) Manufactured nanomaterials: categorization and approaches to hazard assessment. Archives of Toxicology 88:12, pages 2191-2211.
Crossref
Robert Landsiedel, Ursula G Sauer, Lan Ma-Hock, Jürgen Schnekenburger & Martin Wiemann. (2014) Pulmonary toxicity of nanomaterials: a critical comparison of published in vitro assays and in vivo inhalation or instillation studies . Nanomedicine 9:16, pages 2557-2585.
Crossref
Jana Keller, Wendel Wohlleben, Lan Ma-Hock, Volker Strauss, Sibylle Gröters, Karin Küttler, Karin Wiench, Christiane Herden, Günter Oberdörster, Bennard van Ravenzwaay & Robert Landsiedel. (2014) Time course of lung retention and toxicity of inhaled particles: short-term exposure to nano-Ceria. Archives of Toxicology 88:11, pages 2033-2059.
Crossref
Anoop K. Pal, Iraj Aalaei, Suresh Gadde, Peter Gaines, Daniel Schmidt, Philip Demokritou & Dhimiter Bello. (2014) High Resolution Characterization of Engineered Nanomaterial Dispersions in Complex Media Using Tunable Resistive Pulse Sensing Technology. ACS Nano 8:9, pages 9003-9015.
Crossref
Georgios Pyrgiotakis, Christoph O. Blattmann & Philip Demokritou. (2014) Real-Time Nanoparticle–Cell Interactions in Physiological Media by Atomic Force Microscopy. ACS Sustainable Chemistry & Engineering 2:7, pages 1681-1690.
Crossref
Antti Koivisto, Jaana Palomäki, Anna-Kaisa Viitanen, Kirsi Siivola, Ismo Koponen, Mingzhou Yu, Tomi Kanerva, Hannu Norppa, Harri Alenius, Tareq Hussein, Kai Savolainen & Kaarle Hämeri. (2014) Range-Finding Risk Assessment of Inhalation Exposure to Nanodiamonds in a Laboratory Environment. International Journal of Environmental Research and Public Health 11:5, pages 5382-5402.
Crossref
Glen DeLoid, Joel M. Cohen, Tom Darrah, Raymond Derk, Liying Rojanasakul, Georgios Pyrgiotakis, Wendel Wohlleben & Philip Demokritou. (2014) Estimating the effective density of engineered nanomaterials for in vitro dosimetry. Nature Communications 5:1.
Crossref
Christa Watson, Jing Ge, Joel Cohen, Georgios Pyrgiotakis, Bevin P. Engelward & Philip Demokritou. (2014) High-Throughput Screening Platform for Engineered Nanoparticle-Mediated Genotoxicity Using CometChip Technology. ACS Nano 8:3, pages 2118-2133.
Crossref
Georgios A. Sotiriou, Christa Watson, Kimberly M. Murdaugh, Thomas H. Darrah, Georgios Pyrgiotakis, Alison Elder, Joseph D. Brain & Philip Demokritou. (2014) Engineering safer-by-design silica-coated ZnO nanorods with reduced DNA damage potential. Environmental Science: Nano 1:2, pages 144.
Crossref
Robert A. Yokel, Salik Hussain, Stavros Garantziotis, Philip Demokritou, Vincent Castranova & Flemming R. Cassee. (2014) The yin: an adverse health perspective of nanoceria: uptake, distribution, accumulation, and mechanisms of its toxicity. Environ. Sci.: Nano 1:5, pages 406-428.
Crossref
Ramon M. Molina, Nagarjun V. Konduru, Renato J. Jimenez, Georgios Pyrgiotakis, Philip Demokritou, Wendel Wohlleben & Joseph D. Brain. (2014) Bioavailability, distribution and clearance of tracheally instilled, gavaged or injected cerium dioxide nanoparticles and ionic cerium. Environ. Sci.: Nano 1:6, pages 561-573.
Crossref
Samuel Gass, Joel M. Cohen, Georgios Pyrgiotakis, Georgios A. Sotiriou, Sotiris E. Pratsinis & Philip Demokritou. (2013) Safer Formulation Concept for Flame-Generated Engineered Nanomaterials. ACS Sustainable Chemistry & Engineering 1:7, pages 843-857.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.