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Journal of Medical Economics Volume 15, 2012 - Issue 5
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Original Article

Optimizing adherence in hypertension: a comparison of outcomes and costs using single tablet regimens vs individual component regimens

J. D. BelseyJB Medical Ltd SudburyUKCorrespondence[email protected]
Pages 897-905 | Accepted 26 Apr 2012, Published online: 24 May 2012

Citations (22)

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Susanne Roas, Felix Bernhart, Michael Schwarz, Walter Kaiser & Georg Noll. (2014) Antihypertensive combination therapy in primary care offices: results of a cross-sectional survey in Switzerland. International Journal of General Medicine 7, pages 549-556.
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Lin Xie, Feride Frech-Tamas, Elizabeth Marrett & Onur Baser. (2014) A medication adherence and persistence comparison of hypertensive patients treated with single-, double- and triple-pill combination therapy. Current Medical Research and Opinion 30:12, pages 2415-2422.
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Sverre E. Kjeldsen, Franz H. Messerli, Chern-En Chiang, Peter A. Meredith & Lisheng Liu. (2012) Are fixed-dose combination antihypertensives suitable as first-line therapy?. Current Medical Research and Opinion 28:10, pages 1685-1697.
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Articles from other publishers (19)

G. Mancia, F. P. Cappuccio, M. Burnier, A. Coca, A. Persu, C. Borghi, R. Kreutz & B. Sanner. (2023) Perspectives on improving blood pressure control to reduce the clinical and economic burden of hypertension. Journal of Internal Medicine 294:3, pages 251-268.
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N. Martell Claros. (2023) Importance of adherence in the management of hypertension. Hipertensión y Riesgo Vascular 40:1, pages 34-39.
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S. P. Radhoe, E. Boersma, M. Bertrand, W. Remme, R. Ferrari, K. Fox, S. MacMahon, J. Chalmers, M. L. Simoons & J. J. Brugts. (2022) The Effects of a Perindopril-Based Regimen in Relation to Statin Use on the Outcomes of Patients with Vascular Disease: a Combined Analysis of the ADVANCE, EUROPA, and PROGRESS Trials. Cardiovascular Drugs and Therapy.
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S. R. Gilyarevskij, N. G. Bendeliani, M. V. Golshmid, I. M. Kuz’mina & I. G. Andreeva. (2021) THE APPLICATION OF COMBINED PREPARATIONS WITH CONSTANT DOSES OF ANTIHYPERTENSIVE DRUGS AS THE INITIAL TACTICS OF TREATMENT AT HIGH BLOOD PRESSURE LEVEL: PROVEN FACTS AND EXPERT’S OPINION. Eurasian heart journal:2, pages 92-102.
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Zhen-Yu Zhang, Yu-Ling Yu, Kei Asayama, Tine W. Hansen, Gladys E. Maestre & Jan A. Staessen. (2021) Starting Antihypertensive Drug Treatment With Combination Therapy. Hypertension 77:3, pages 788-798.
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Erika Campana, Vitória Cunha, Sigita Glaveckaite, Ivan Gruev, Guillaume Lamirault, Elke Lehmann, Stefano Masi, Liliane Mfeukeu Kuate, Larysa Mishshenko, Deborah I.D. Ona, Min Zaw Oo, Oana G.F. Tautu, Anna Vachulova, Ana-Maria Vintila, Jacek Wolf, Nadezhda Zvartau, Krzysztof Narkiewicz & Stephane Laurent. (2020) The use of single-pill combinations as first-line treatment for hypertension: translating guidelines into clinical practice. Journal of Hypertension 38:12, pages 2369-2377.
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Neil R. Poulter, Claudio Borghi, Gianfranco Parati, Atul Pathak, Diana Toli, Bryan Williams & Roland E. Schmieder. (2020) Medication adherence in hypertension. Journal of Hypertension 38:4, pages 579-587.
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Anna F. Dominiczak, Martine de Champvallins, Romualda Brzozowska-Villatte & Roland Asmar. (2019) Efficacy of a new single-pill combination of a thiazide-like diuretic and a calcium channel blocker (indapamide sustained release/amlodipine) in essential hypertension. Journal of Hypertension 37:11, pages 2280-2289.
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Zh. D. Kobalava, E. A. Troitskaya, M. A. MarkovaY. V. Khruleva. (2019) Medical adherence in hypertensive patients treated by triple fixed-dose combination of amlodipine / indapamide / perindopril arginine (results of the Study DOKAZATEL’STVO). "Arterial’naya Gipertenziya" ("Arterial Hypertension") 25:3, pages 285-294.
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Kostas Tsioufis, Stella Douma, Manolis S. Kallistratos & Athanasios J. Manolis. (2019) Effectiveness and Adherence to Treatment with Perindopril/Indapamide/Amlodipine Single-Pill Combination in a Greek Population with Hypertension. Clinical Drug Investigation 39:4, pages 385-393.
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Stelina Alkagiet & Konstantinos Tziomalos. (2018) Suboptimal Adherence to Antihypertensive Treatment: Causes and Management. The Open Hypertension Journal 10:1, pages 41-45.
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Amol A. Verma, Wayne Khuu, Mina Tadrous, Tara Gomes & Muhammad M. Mamdani. (2018) Fixed-dose combination antihypertensive medications, adherence, and clinical outcomes: A population-based retrospective cohort study. PLOS Medicine 15:6, pages e1002584.
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Peter Bramlage, Stefanie Schmidt & Helen Sims. (2018) Fixed‐dose vs free‐dose combinations for the management of hypertension—An analysis of 81 958 patients. The Journal of Clinical Hypertension 20:4, pages 705-715.
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J. J. Brugts, M. Bertrand, W. Remme, R. Ferrari, K. Fox, S. MacMahon, J. Chalmers, M. L. Simoons & E. Boersma. (2017) The Treatment Effect of an ACE-Inhibitor Based Regimen with Perindopril in Relation to Beta-Blocker use in 29,463 Patients with Vascular Disease: a Combined Analysis of Individual Data of ADVANCE, EUROPA and PROGRESS Trials. Cardiovascular Drugs and Therapy 31:4, pages 391-400.
Crossref
Jean-Jacques Mourad, Celso Amodeo, Martine de Champvallins, Romualda Brzozowska-Villatte & Roland Asmar. (2017) Blood pressure-lowering efficacy and safety of perindopril/indapamide/amlodipine single-pill combination in patients with uncontrolled essential hypertension. Journal of Hypertension 35:7, pages 1481-1495.
Crossref
Alpesh Amin & Joel C. Marrs. (2016) Direct Oral Anticoagulants for the Management of Thromboembolic Disorders. Clinical and Applied Thrombosis/Hemostasis 22:7, pages 605-616.
Crossref
Katarina Hatalova, Daniel Pella, Rastislav Sidlo & Robert Hatala. (2016) Switching from a Free Association of Perindopril/Amlodipine to a Fixed-Dose Combination: Increased Antihypertensive Efficacy and Tolerability. Clinical Drug Investigation 36:7, pages 591-598.
Crossref
Tracey-Lea Laba, Beverley Essue, Merel Kimman & Stephen Jan. (2014) Understanding Patient Preferences in Medication Nonadherence: A Review of Stated Preference Data. The Patient - Patient-Centered Outcomes Research 8:5, pages 385-395.
Crossref
Giuseppe Mancia, Roland Asmar, Celso Amodeo, Jean-Jacques Mourad, Stefano Taddei, Marco Antonio Alcocer Gamba, Irina E. Chazova & Juan G. Puig. (2015) Comparison of single-pill strategies first line in hypertension. Journal of Hypertension 33:2, pages 401-411.
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